LOCUS       NM_001143803            4441 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus inhibitory synaptic factor 2A (Insyn2a), mRNA.
ACCESSION   NM_001143803
VERSION     NM_001143803.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4441)
  AUTHORS   Uezu,A., Kanak,D.J., Bradshaw,T.W., Soderblom,E.J., Catavero,C.M.,
            Burette,A.C., Weinberg,R.J. and Soderling,S.H.
  TITLE     Identification of an elaborate complex mediating postsynaptic
            inhibition
  JOURNAL   Science 353 (6304), 1123-1129 (2016)
   PUBMED   27609886
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000001.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360190.726691.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840110 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-434               JAXUCZ010000001.1  199182366-199182799 c
            435-1596            JAXUCZ010000001.1  199162861-199164022 c
            1597-1668           JAXUCZ010000001.1  199144718-199144789 c
            1669-4441           JAXUCZ010000001.1  199127738-199130510 c
FEATURES             Location/Qualifiers
     source          1..4441
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..4441
                     /gene="Insyn2a"
                     /gene_synonym="Fam196a; Insyn2"
                     /note="inhibitory synaptic factor 2A"
                     /db_xref="GeneID:100233213"
                     /db_xref="RGD:2302685"
     exon            1..434
                     /gene="Insyn2a"
                     /gene_synonym="Fam196a; Insyn2"
                     /inference="alignment:Splign:2.1.0"
     exon            435..1596
                     /gene="Insyn2a"
                     /gene_synonym="Fam196a; Insyn2"
                     /inference="alignment:Splign:2.1.0"
     CDS             440..1852
                     /gene="Insyn2a"
                     /gene_synonym="Fam196a; Insyn2"
                     /note="protein FAM196A; family with sequence similarity
                     196, member A"
                     /codon_start=1
                     /product="inhibitory synaptic factor 2A"
                     /protein_id="NP_001137275.1"
                     /db_xref="GeneID:100233213"
                     /db_xref="RGD:2302685"
                     /translation="MVSKDTGRCILTTPEQEVEPAACLALEMRYALDPNRQIKKRNKA
                     LQVRFKDICEAQNEQRDTQLSSGPLGEKREAKAVSCRVAYRKYMTVPARRSIPNVTKS
                     TGVQTSPDLRKCYQTFPLDRKKGSLKGLPAADTFKSQNNGFLADSKEKSEAGPTEDPR
                     PCSAGRIHKTTALVFHSNEHVNALDQPSGVNCAELCKSPDVLGYPEALLQNSRPPSEE
                     PIHQLQGRAKPDRGTLDSEEPTPLTHGRVFKTEVATVYPPAKSTRAPEPGLSNSAAAS
                     QWSLCPTEEEQRRAAHLNGLQVSTGSAVACSTPVQCLSPECSEQPLQNQPSPTAGVGD
                     EERQQIVPHTEVVDLKAQLQVMENLISSSQETIKVLLGVIQELEKGEAHREGLSYRTG
                     QDTANCDTCRNSACIIYSVELDFKQQEDKLQPVLRKLHPVEETQVAPLPYTQEAHSST
                     PKQKSKTESKKHGRWKLWFL"
     exon            1597..1668
                     /gene="Insyn2a"
                     /gene_synonym="Fam196a; Insyn2"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..4441
                     /gene="Insyn2a"
                     /gene_synonym="Fam196a; Insyn2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccccgtctcc gccccctcct cccggccccg gatctcgctg aagacaattg cagtaaatga
       61 ggacatctga ggagcacgga gccgggtggc tgtggctggc tccgccgcgc cgcgatcggg
      121 cgagcgcgcg ggcgtccccg gagccggccg agccactgcc tccccgtgcg cgtcgctgag
      181 caggagccga agggactcga gctgcggcgc gggggccggc cgggccgggc ccgtggcagt
      241 ggagggggcg ggcggcgggc acgcagctgg ccaagtcccc gaagccgagc ctccttcagc
      301 gcgagccccg cgatccttgc cgtggatgct ctgccccgag tgctccgtgc cgcgccaggc
      361 ttgccagggt ccgcggcaag acatgcctga gccaggcgct gcaccgacct ccacttacca
      421 gtaagcagcc aaaggcacca tggtcagcaa ggacactggc agatgcatac tcacaacacc
      481 agagcaggaa gtggagcccg ccgcctgcct ggccctggag atgagatacg ccctggaccc
      541 caacaggcag atcaaaaagc gtaacaaagc cctgcaggtg cgctttaagg atatctgtga
      601 ggcccagaat gagcagagag acacacagtt gtcttcggga cctctggggg agaagcgaga
      661 ggccaaggct gtgtcctgca gggtggcata tcgtaagtat atgacggtgc ccgcacgccg
      721 gtccattccc aacgtcacca agagcaccgg tgttcagacc tcaccggacc ttcgcaagtg
      781 ttaccagaca ttcccgctgg accgcaagaa aggcagtctc aaaggcctgc cagctgcaga
      841 taccttcaaa agccagaaca atgggtttct agcagattca aaagagaaga gcgaggcagg
      901 gcccacggag gaccctcggc cttgcagtgc aggaaggatt cacaagacca cagcattggt
      961 tttccattcc aacgaacacg tgaatgcgct ggaccagccc tctggggtca actgtgcgga
     1021 gctctgcaag tccccggatg tgctcggcta ccctgaggct cttttgcaga actctcggcc
     1081 tccctctgag gagcccatcc accagctgca ggggagagct aagcctgaca ggggcaccct
     1141 ggactcagag gaacccactc cactcaccca tggaagggtg tttaagacag aggtcgccac
     1201 tgtgtatcca cctgccaaaa gcaccagggc ccctgagcct ggcttgtcaa actctgctgc
     1261 tgccagccaa tggtctctct gccctacaga ggaggagcag aggcgggccg cccacctcaa
     1321 tgggctgcag gtatccacag gctcggctgt ggcctgctca accccggtgc agtgcctgtc
     1381 cccagaatgt agcgaacagc ccctgcagaa ccagcctagc cccacagctg gggtagggga
     1441 tgaagaacgc caacaaattg tgcctcacac agaagtggta gacctcaagg cccagctgca
     1501 ggtgatggag aacttaatca gctccagcca ggagaccatc aaagtgctgc tgggagttat
     1561 tcaggagctg gagaaaggag aagcccatcg ggaagggctt tcatatcgga cggggcaaga
     1621 cacagctaat tgtgacacgt gcaggaacag tgcatgtatt atctatagtg tggagctgga
     1681 ttttaagcag caagaagaca aactgcagcc cgtgctgaga aaactgcacc ctgtcgagga
     1741 aactcaggtc gcccctttgc cttacactca ggaggctcac tcctccacgc ccaagcaaaa
     1801 atccaaaact gagtccaaaa agcacggaag gtggaaactc tggttccttt aatctcgtgg
     1861 gcttgggaag acccagactg tcttttaacc ccactggaat ttaagtgagt cctttcccga
     1921 aacggatagg atcaagggaa ctgcggtgcc aacgcgtgct ccctgcttct cgccctgcgt
     1981 accaaaaagg ccttcgcacc aacagataat tagcagcaag ggagtgactg tcaccccttg
     2041 ccagctgtcc tttgcagtcc actggtatgg ggtataaagt ctgaaataaa acttacgcag
     2101 ttaaagataa ggaataactc tccccccgac agtgcccctt gcctaagaag gagtgttgag
     2161 ataccagtgc cccacacggc aggctgtcct ggtagccggt gggacctctc actattttgg
     2221 ctctctatta ttatttatct ttaagtgaga agagaaagca agcctcgagt tggcaaagga
     2281 cttcattttt acctttcatt atgaaataag caggggcgag tgcagttttc agcacattca
     2341 attccggaga aagcacaatt tttttttttc aagtggtcgg agaccatgaa taatctcgaa
     2401 aaatgtgact ctatgtatat ctgccttcgt gtgctgtagc gctaagccaa gtgaccacat
     2461 ctcagtgtca cattgacacc acagatttag aaccctcttc atctccaggt ggacaacatg
     2521 tttactgttc atttcccaaa tggccagcag ccaggaacca ctcccacccc cacccgagtc
     2581 ataatatgcc ttcagtcatt gcaagctgac agggtcagag ctactggaca ctaagctttc
     2641 ttagatgttg tttttattct ttgggtaccc aaaggccaaa tgatgaatct ggcaagaatt
     2701 ggaaagcaga cagagataca cagtgggtga catagttacc tataaatcac gggtgcctgg
     2761 gctgcagcag aaagcattgg ttcgtttgtt tgtttattca ttcattcatt ttatttattt
     2821 atttatttat ttatttattt atttatttat ttattattta tctctgagcg cagccaggta
     2881 ttttatacag ttctttacgc tttgtctcta ctgggcgaga tctgaccatc acagagagaa
     2941 acagcctgtt tcccttagct gctaccaatg gccaaattta ccatcaccta catttaaccg
     3001 atcagtaaac tgtattaaat ggcatactta ggggaaagct gtgaatcaaa tggttttagg
     3061 attttaaaaa acccactgta taattgagag tattctcttg attacacatg accacgtaaa
     3121 cctccatccc cttgttttgt tttgctcatt tctttgcacc tttacaagta tcttttttat
     3181 agaaaccaaa atcctcttgt gcactaatga cgtctctcag tattctgctt ctcgtgtagg
     3241 aagcagaggg tcttttttgg ccttttgttt ttttcttttt gtataacaat gttttgaatt
     3301 gtttgtgggc gtaccagaaa gacctagggt ttggtgttgg tccagcactt tcagctggaa
     3361 ctgcacgctg atggcagcct ggcagatcag actgcaagct tgcagcggct ccgtattggg
     3421 agagggtcat gaccttcttt ggatgggtag gaactagggc tcaccacatg cttttcctca
     3481 tttagttcta aatatttgga ttatacaaca agctttaaaa gaaaaaaaaa aaggctaaaa
     3541 gaatattttg tgtgaatccc ctttggggac tactcaaacc acactagagg tatgcttatt
     3601 taaaatgcaa ggacatgtgc atgcatgcat gcacacacaa aatacacaca cacacaaata
     3661 cagacacaca cacagaacac ttgtgcccat acacgcacac acaaaacaca ctgtgcacac
     3721 acacacatac acacacacac acgcacgcac gcacgcacgc gcgcgcgcac gcaaacacat
     3781 gcctatacgg aagtactctc caagaatata aatctgcaga agagcagtaa acaagacgtg
     3841 tcgcagaaga gccctgacca agctgatcct gtaccttgac ggaagtgcaa ttgttccatg
     3901 cacactaaac tttaaacatg tgtttcatgt ttttatactg tttttaactg atgttgcaaa
     3961 ggtgttcacg acgagttttc tcttcctctg tttgaagaat cccatgttct caccgagtgg
     4021 aaggaagggt tcagcagctt tctgtccagt gctgcacaac tgtctagatg caagcctgtg
     4081 tgactacctg tgacgtcctt gtttccaacc agtctaggcc cccacacaaa aagattaaac
     4141 acctgagaac cagaaatgaa actctgaaga taaactcatt cctcctcaaa aggaaaagca
     4201 tctccccaaa ctggaaacaa aatatactgt caagttcatt tcatagctga atcacaaatt
     4261 tgccaatgac agaggatgac ccttctcccg ggaagatcga actcaaaaat ttcatacaaa
     4321 actaagtaat cagttcagtg tcccctccta tgtagatgta cacatggcat tacgtataga
     4381 gagtaaatta ttatacttgt cattaaatct ttattaattt ttaaataaaa aaaatcaaag
     4441 g
//
