LOCUS       NM_001106285            2341 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus INSC, spindle orientation adaptor protein (Insc),
            mRNA.
ACCESSION   NM_001106285 XM_001074874 XM_218982
VERSION     NM_001106285.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2341)
  AUTHORS   Yuzawa,S., Kamakura,S., Iwakiri,Y., Hayase,J. and Sumimoto,H.
  TITLE     Structural basis for interaction between the conserved cell
            polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched
            protein (LGN)
  JOURNAL   Proc Natl Acad Sci U S A 108 (48), 19210-19215 (2011)
   PUBMED   22074847
REFERENCE   2  (bases 1 to 2341)
  AUTHORS   Izaki,T., Kamakura,S., Kohjima,M. and Sumimoto,H.
  TITLE     Two forms of human Inscuteable-related protein that links Par3 to
            the Pins homologues LGN and AGS3
  JOURNAL   Biochem Biophys Res Commun 341 (4), 1001-1006 (2006)
   PUBMED   16458856
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473956.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_218982.4, XM_001074874.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN16676784,
                              SAMN16676787 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2341
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q34"
     gene            1..2341
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /note="INSC, spindle orientation adaptor protein"
                     /db_xref="GeneID:293166"
                     /db_xref="RGD:1311379"
     exon            1..258
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /inference="alignment:Splign:2.1.0"
     CDS             163..1902
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /note="inscuteable homolog"
                     /codon_start=1
                     /product="protein inscuteable homolog"
                     /protein_id="NP_001099755.1"
                     /db_xref="GeneID:293166"
                     /db_xref="RGD:1311379"
                     /translation="MRRPPGDGDSTGEGPGNWGLWGAQESRRLCCVGPDRCGQALLQI
                     GMNMMALPGGRHLGSIPLQEQRLHFMQVDSVQRWMEDLKLMTECECMCVLQAKPISLE
                     EDTQSDLILAGGPGPGDPLQLLLKRGWVISTELRRIGQKLAQDRWARVHSMSVRLTCH
                     ARSMVSEYSTISRTTSQEMGQAEKLLMEKCSELSAVTERCLQVENEHVLKSMKACVSE
                     TLSMLGQHFGQLLELALTREVQALVRKIDTSDNIYITESTTGNLFSLTQEGAPLCRII
                     AKEGGVVALFKVCRQDTFRCLYPQALRTLASICCVEEGVHQLEKVDGILCLTDILTDD
                     SHSEATRAEAAAVVAQVTSPHLSFTQHLTSFLENMEEIVTALIKLCQEASSGEVFLLA
                     SAALANITFFEKMACEMLLQLNAIRVLLEACGDKQRVDTPYTRDQIVTILANMSVLEQ
                     CASDIIQENGVQLIMGMLSEKPRSGTPAEVAACERVQQKAAVTLARLCRDPDVAREAV
                     RLSCMSRLIELCRSPSERNSSDAVLVACLAALRRLAGVCPEGLQDSDFQQLVQPRLVD
                     SFLLCSNMEESFV"
     exon            259..359
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /inference="alignment:Splign:2.1.0"
     exon            360..705
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /inference="alignment:Splign:2.1.0"
     exon            706..758
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /inference="alignment:Splign:2.1.0"
     exon            759..882
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /inference="alignment:Splign:2.1.0"
     exon            883..996
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /inference="alignment:Splign:2.1.0"
     exon            997..1122
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1294
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1473
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /inference="alignment:Splign:2.1.0"
     exon            1474..1540
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /inference="alignment:Splign:2.1.0"
     exon            1541..1696
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..1773
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /inference="alignment:Splign:2.1.0"
     exon            1774..2341
                     /gene="Insc"
                     /gene_synonym="RGD1311379"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagccttag tcctgagcag ccttgagagt ctgcccattg gcctttgctt tgaatctcag
       61 gccttctcag gtccatggcc cagaaggatg ggtggagaga atgaagctgc tcacaggggc
      121 ctccgtaaga acacctaaat cactatagcc cagactgtga ccatgaggcg gcccccaggg
      181 gatggagact ccaccggaga aggcccagga aactggggct tatggggagc ccaggagtcc
      241 aggaggctgt gctgtgttgg gccagaccgc tgtgggcagg cactactgca gattggaatg
      301 aacatgatgg cactacctgg aggccggcac ctgggttcca ttcctctgca agagcagagg
      361 ctacacttca tgcaggtgga ctcggttcag cgctggatgg aggatctgaa gctcatgacc
      421 gagtgtgagt gcatgtgcgt cttgcaggca aagcccatca gcctggagga agacacgcag
      481 agtgacctta tcctagcagg tggtcctgga ccaggagatc ctctgcagct gctcctgaag
      541 cggggctggg tcatcagcac agagcttcga aggatcgggc agaagctggc ccaggaccgc
      601 tgggcacgcg tgcacagcat gagtgtgcgt ctgacgtgcc atgcacgttc catggtcagc
      661 gagtacagca ccatcagcag gacaacctcg caggaaatgg gccaggcaga gaagctgctc
      721 atggagaaat gctccgagct ctctgcggtc actgagaggt gcctccaagt ggaaaatgag
      781 catgttctga agtcaatgaa ggcctgcgtg agtgagaccc tgagcatgtt gggccagcac
      841 tttggccagc tactggaact ggccctcaca cgggaagtgc aggcacttgt gagaaaaatc
      901 gatacctcag acaatatcta catcacggaa tctaccacag ggaacctctt cagcctgacc
      961 caggaggggg ctcctttgtg ccgcatcata gccaaggaag gtggggttgt agccctcttc
     1021 aaggtctgcc ggcaggacac cttccggtgt ttgtaccccc aggcgctccg cacactggcc
     1081 tctatctgct gtgtggaaga gggtgtccat cagctggaaa aggtggatgg tatcctgtgc
     1141 ttgacggaca tcttgactga tgatagccac tcagaggcca ctcgagctga ggctgcagcc
     1201 gtggtagccc aggttacctc tccacatctg tctttcaccc agcacctcac tagctttctg
     1261 gagaacatgg aggagattgt gacagcccta atcaaactgt gccaagaggc ctcatcaggg
     1321 gaagtcttcc tgctggcttc tgcggccctt gccaatatca ccttcttcga aaaaatggcc
     1381 tgtgagatgc ttctgcagtt gaatgcaatc cgtgtccttc tggaagcctg tggtgacaaa
     1441 cagagagtag acacacctta tactcgggac cagattgtga ccatcttggc aaacatgtct
     1501 gtgctggagc agtgtgcctc tgacatcatt caggagaatg gtgtccagct catcatgggc
     1561 atgctgtcgg agaagccaag gtctgggacg cctgctgaag tggcagcctg tgagagagta
     1621 cagcagaaag ctgcagtgac cctggcccgc ctctgccgag acccagatgt ggcccgggag
     1681 gctgtgcggc tcagctgtat gtctcgcctg attgagctct gcagatcccc ctctgagagg
     1741 aacagcagcg atgccgtcct ggtagcctgc ctggctgcct tgcgtcgctt ggctggggtc
     1801 tgccccgaag gccttcagga ctctgacttc cagcagctgg tccagcctcg gcttgtggat
     1861 tccttcttgc tgtgtagcaa tatggaggag agttttgttt agtgagcatg ggagaggata
     1921 cacactgtgc gcactcaaca tgctagccct cctcagctcc ctatttatac ataatttatt
     1981 tttttacatg aaatagaaag ggaaatcatc agtgagtagc gggtcctcag gcatactctc
     2041 tctctctctc tctctctctc tctctcttct gtggctgtgt aggtacagag gttgaattgt
     2101 gtcaaggcta acatgacagg ttgtcacagg tgactcccct ttctaatgct tcctttctct
     2161 tgaatatatt cttgcctatt taaaaacaca aaacaaaaca gctcaacttt gaaccagggc
     2221 attttaactg cccagcattt tttaaaagtt agttttactc ttttcagaaa tttaaagtga
     2281 attatgcagt tgaaaagaca tactgtaagg aaatgttttt ctttaataaa tggaatcatg
     2341 a
//
