LOCUS       XM_039096594           25711 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus insulin 2 (Ins2), transcript variant
            X6, mRNA.
ACCESSION   XM_039096594
VERSION     XM_039096594.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25711
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..25711
                     /gene="Ins2"
                     /gene_synonym="CP-II"
                     /note="insulin 2; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 912 ESTs, 18 Proteins,
                     and 100% coverage of the annotated genomic feature by
                     RNAseq alignments, including 2 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:24506"
                     /db_xref="RGD:2916"
     CDS             25292..25651
                     /gene="Ins2"
                     /gene_synonym="CP-II"
                     /codon_start=1
                     /product="insulin-2 isoform X1"
                     /protein_id="XP_038952522.1"
                     /db_xref="GeneID:24506"
                     /db_xref="RGD:2916"
                     /translation="MPSCGHCSNMALWIRFLPLLALLILWEPRPAQAFVKQHLCGSHL
                     VEALYLVCGERGFFYTPMSRREVEDPQVAQLELGGGPGAGDLQTLALEVARQKRGIVD
                     QCCTSICSLYQLENYCN"
ORIGIN      
        1 cacacacacc cagacacact cacctgaatt ttagtaacca aatagatatc cttggttttc
       61 ctgaactgcc attttgaata gttcccaagg aatacatgta aaacacaatt ttcattatta
      121 caatttcaac tatctttgtt tactatgtct tctgagaaga caggactctc aggaaaaaca
      181 aaacagtata agtaattaag gagagtacaa gcaaaggttt tacacaacaa aaacatacag
      241 gaaagggaag tatggacaca ggagctagaa aggttgctag aacaaagctt ccgaacttca
      301 tatatcagac ccaagaacag agaaataaca ataaattttg gaagctgagc ctagagaacg
      361 gtttagaggt tgaaaattaa aattagggag atacagagag aaacaatgac aaatttggaa
      421 gagagaggga tagggagaga gagaaagaga gagaggcaaa agaaaagaac cggtgagaac
      481 atagagagct gtagtagtat gcagtccttt tatacaaaac ccatgagtag tacaattggt
      541 ggcagtgatg tctttgggct ccagtgagta ttggggatga cattaaaccc ctttgagata
      601 acagggaagt ctttcagaca cagccttcct gaaaaccttg gaaagcctta agtccagaaa
      661 tatacttggt cagaattgag gtgccaacgt gaatttcaga aactctgtag aaggaagaaa
      721 ctccttaggg gaaggtctta ggtcccacgg agatcctgag aaggtctgag cactgaagta
      781 gaaccttagg aaggaatcca tagaggtccg agtactgagg acggccctgg atccctgtga
      841 ctccctaaag aggtcttagt gaatggtgag aggtaaaggc cttctcatac tctcagaaac
      901 ttggaaaccc tctgggaaca gatgagtact caagagacat tattctgcaa ggaagtccag
      961 tgagagtctc aaaatattta cattcatgtt agcatcttat gacggccatg agccccagtg
     1021 agtgtcatga gcagggagga aggtatttgt cttcttagca aaagacaagt ggtcatcctg
     1081 aggttctcca cccatggttc ccacaagttc ctaaccacta tgctattcct ccctgttcaa
     1141 ggctgctcag tctatggcag ttccaagttt tccttacgat ctatagcccc caggtggttg
     1201 tacctgaatc caagaacttc cgcagtatga caaacataat ttttgaaaaa gcctttgagt
     1261 cataagataa aaaagcttaa attctggaaa cccacagtgc ccagcctgtg cctgataatc
     1321 agactgcagg tatatcaatt actagagata atctgacatg tgacagaaca aagtgacaat
     1381 gccacctccc cacttgagag tatataatca gagaacaaaa gtaatgcata gtactttgcc
     1441 cttacaggac tgctgaagac tttgaaaggg actatgttgg tcttccctac ggatggaggg
     1501 tttcctgcga tcttaaccat tcaactgcct ccttccgtga aataattgag ccaagattca
     1561 gataagattc ttcaggcagg acacagaaca gccagacctg ctgtacagaa ggcttgcact
     1621 gcagacagcc ccagatcgca gcacatagtg ccagcaggcg tgcaaacaga catggctcag
     1681 aaggcttggg tccttctcca attagctcgt gcctgcatat aaaagatttg gagagtactg
     1741 cggtgttctg aatggaaaag agagagaata agagaaaggc actagaactc tgaatcagga
     1801 ctgctgaaga ctttgaaagg gactatgttg gtcttcccta cggatggagg gtttcctgcg
     1861 atcttaacca ttcaactgcc tccttccgtg aaataattga gccaagattc agataagatt
     1921 ctccaggcag gacacagaac agccagacct gctgtacaga cggcttgcac tgcagacagc
     1981 cccagatcgc agcacatagt gccagcagcc gtgcaaacag agatggctca gaaggcttgg
     2041 gtccttctcc aattagctcg tgcctgcata taaaagattt ggagagtact gcggtgttct
     2101 gaatggaaaa gagagagaat aagagaaagg cactagaact ctgaatcagg actgctgaag
     2161 actttgaaag ggactatgtt ggtcttccct acggatggag ggtttcctgc gatcttaacc
     2221 attcaactgc ctccttccgt aaaataattg agccaagatt cagataagat tcttcaggca
     2281 ggtgagacgc ttgggaagat agatttatga ccttagttag ggacttggcc atatacctat
     2341 gggaagacac tcagcataag aaactacatc ttttcttcta gcaactgtgc ataccgaccg
     2401 tcgagatcaa aacaggcagg gaattactgg gtaggcctta ggtgtccatg agatcctggg
     2461 atggcatgag gctccaggta gacacaggag actgctcaga acctagtttc aatctggcat
     2521 attattggac atcagtgaga ctctgacaga agaaaaggta ccggatacat tctcctgaca
     2581 acgtgacacc tcaatggtaa tttagagaat gtactagtcc tctgaaaata cctgggaaaa
     2641 gctttggacc ctagaaacat catagaaatg gaacaggttc cagtgagaaa ctggagcagg
     2701 attgagtcca agagagaacc aaggaaaaca ttcgagtcca aggaagtcct aaggaagact
     2761 ttaagcctta atgagaacct aagacagact ttagatccga aggaaaatct ctggtaagct
     2821 atagccatga gtgagaagga ggggaatgat ttcttcctca gtgagaatgt ggaagactgt
     2881 tagaaccagt gaaaaaccac agtttggatt tggtgaggcc ttaggtttcc gtgaatacct
     2941 tttgaaagcc ttgggtcgca gtaagaacgc caaaagctct tctatcccgg ggaggtattg
     3001 cagaagactt taaatgctgt gtgatcctgg ggaccttctt agactgacag agaatctagg
     3061 caaaacctta ggttcaactt tgcaatattg taggacacac atcgaaccct gtcaaggcct
     3121 gagaccttgt gtttctcagg aaggcctaac atgccagtgt aatcttgcca gaagttcacg
     3181 acacactgag agtctctaag atcctttctt tttcacaaag aacctaggga aaacagaggt
     3241 ctcaataaca ctttgaagaa ggccttaacc atatggagat cttttggaat gttgtacgtc
     3301 gcatttcgaa catgaagaaa gccttcattc ccatccctac attccatgag aaattgagaa
     3361 atatattggc ccacttgata ccccgtatag gctctagcaa gatgctgtgc aaggaattag
     3421 gccacagata cgacttggaa agccacaggg gtaacctggg aacccttgtg ggtcttgcgc
     3481 cataggcttc attgcgtctt tggagggagg tcttaaagca tacgttgtgt tcccatttaa
     3541 attatccatc cagtcctgct ttttgtatta tgatgctaat tctgtcccca gacagcagac
     3601 caccaagtac ccaggtgatc tcatgggaac cgtcttccta tattaacctg tcaataaatc
     3661 tagggcatgt gattggagac tagaagggaa aggtgagact ggaggtttga cagtgatagc
     3721 attaggagag aaagaagggc aaaagagcaa ggagagtggc ctgtagagga ggagctgaga
     3781 ttgacctgat tgcattggat tgtatgttct atatatggtc tcatttgctt tggaaattag
     3841 agcaacaaaa tggctccaaa cctggggatt agaacccaag caacttgagg gaaaattcac
     3901 tcctccccac tataggcaag tagggctggg ctgtaaagtt gcctcggggt gaaaaatgat
     3961 acacctagtg ggtctacaag tttctataga tctactgaga acctccctcc catgccccat
     4021 tcagaccatg acagtaaccc atctctgagc tcagatttag ccccagtacc aatgtcacaa
     4081 catagttggg gttcgttgag cctaaaagga ccaaggacgc tggggtaggt cttcctgtga
     4141 aacatcagag cttagcatca agaggtgaga agcttgggaa gatagattta tgaccttagt
     4201 tagggacttg gccatatacc tatgggaaga cactcagcat aagaaactac atcttttctt
     4261 ctagcaactg tgcataccga ccgtcgagat caaaacaggc agggaattac tgggtaggcc
     4321 ttaggtgtcc atgagatcct gggatggcat gaggctccag gtagacacag gagactgctc
     4381 agaacctagt ttcaatctgg catattattg gacatcagtg agactctgac agaagaaaag
     4441 gtaccggata cattctcctg acaacatgac acctcaatgg taatttagag aatgtactag
     4501 tcctctgaaa atacctggga aaagctttgg accctagaaa catcatagaa atgtaacagg
     4561 ttccaatgag aaactggagc aggattgagt ccaagagaga accaaggaaa acattcgagt
     4621 ccaaggaggt cctaaggaag actttaagac ttaatgagaa cctaagacag actttagatc
     4681 cgaaggaaaa tctctggaca cagaacagcc agacctgctg tacagacggc ttgcactgca
     4741 caccgcccca gattgctgca tatgcagcca gcagctgttc aaataaacag acatggctca
     4801 gaaggcttgg gtccttctcc aattagctcg tgcctgcata taaaagattt ggagagtact
     4861 gcggtgttct gattgtaaaa gagagagagt aagagaaagg cactagaact ctgaatcagg
     4921 actgctgaag actttgaaag ggactatgtt ggtcttccct acggatggag ggtttcctgc
     4981 gatcttaacc attcaactgc ctccttccgt taaagaattg agccaacatt cagataacat
     5041 tcttcaggca ggacacagaa cagccagacc tgctgtacag acggcttgca ctgcacaccg
     5101 ccccagattg ctgcatatgc agccagcagc tgttcaaata aacagacatg gctcagaagg
     5161 cttgggtcct tctccaatta gctcgtgcct ccatataaaa gatttggaga gtactgcggt
     5221 gttctgaatg gaaaagagag agagtaagag aaaggcacta gaactctgaa acaggactgc
     5281 tgaagatttt gaaagggact atgttggtct tccctaggga tggagggttt cctgcgatct
     5341 taaccattca actgcctcct tccctgaaag aattgagcca agattcagat aagattcttc
     5401 aggcagcaac tgtgcatacc gaccgtcgag atcaaaacag gcagggaatt actgggtagg
     5461 ccttaggtgt ccatgatcct gggatggcat gaggctccag gtagacacag gagactgctc
     5521 agaacctagt ttcaacctgg gatattatta gacatcagtg agactctgac agaagaaaag
     5581 gtaccggata cattctcctg acaacatgac acctcaatgg taatttagag aatgtactag
     5641 tcctctgaaa atacctggga aaagctttgg accctagaaa catcatagaa atggaacagg
     5701 ttccagtgag aaactggagc aggattgagt ccaagagaga accaaggaaa acattcgagt
     5761 ccaaggaggt cctaaggaag actttaagcc ttaatgaaaa tctaagacag actttagatc
     5821 tgaaggaaaa tctctggtaa gctatagcca tgagtgagaa ggaggggaat gatttcttcc
     5881 tcagtgagaa tgtggaagac tgttagaacc agttaaaaac cacagtttgg atttggtgag
     5941 gccttaggtt tccgtgaata ccttttgaaa gccttgggtc gcagtaagaa cgccaaaagc
     6001 tcttctatcc cggggaggta ttgcagaaga cgttaaatgc tgtgtgatcc tggggacctt
     6061 cttagactga cagagaatct aggcaaaacc ttaggttcaa ctttgcaata ttgtaggaca
     6121 cacatcgaac cctgtcaagg cctgagacct tgtgtttctc aggaaggcct aacatgccag
     6181 tgtaatcttg ccagaagttc acgacacact gagagtctct aagaaccttt ctatttcaca
     6241 aagaacctag ggaaaacaga ggtctcaata acactttgaa gaaggcctta accatatgga
     6301 gatcttttgg aatgttgtac gtcgcatttc gaacatgaag aaagtcttca ttcccatccc
     6361 tacattccat gagaaattga ggaatatatt ggcccacttg ataccccgta taggctctag
     6421 caagatgctg tgcaaggaat taggccacag atacgacttg gaaagccaca ggggtaacct
     6481 gggaaccctt gtgggccttg cgccataggc ttcattgcgt ctttggaggg aggtcttaaa
     6541 gcatacgtag tgttcccatt taaattatcc atccagtcct gctttttgta ttgtgatgct
     6601 aattctgccc ccagacagca gaccaccaag tacccaggtg atctcatggg aaccgtcttc
     6661 ctatattaac ctgtcaataa atctagggca tgtgattgga gactagaagg gaaagttgag
     6721 actggaggtt tgacagtgat agcattagga gagagagaag ggcaaaagag caaggagagt
     6781 ggcctgtaga ggaggagctg agattgacct gattgcattg gattgtatgt tctatatatg
     6841 gtctcatttg ctttggaaat tagagcaaca aaatggctcc aaacctgggg attagaaccc
     6901 aagcaacttg agggaaaatt cactcctccc cactataggc aagtagggct gggctgtaaa
     6961 cttgcctcgg ggtgaaaaat gatacaccta gtgggtctac aagtttctat agatctactg
     7021 agaacctccc tcccatgccc cattcagacc atgacagtaa cccatctctg agctcagatt
     7081 tagctccatt accaatgtca caacatagtt ggggttcgtt gagcctaaaa ggaccaagga
     7141 cgctggggta ggtcttcctg tgaaacatca gagcttagca tcaagaggtg aaaaaatggt
     7201 agcccacttt gcaaaggctt ctcacgggca caggaagctg atcaggtgtc tccaccaaag
     7261 caagccttcc tgtgctcgct ttcctttctc tcccatgtct caacaggaca cagaacagcc
     7321 agacctgctg tacagacggc ttgcactgca caccgcccca gatcgctgca tatgcagcca
     7381 gcagctgttc aaataaacag acatggctca gaaggcttgg gtccttctcc aattagctcg
     7441 tgcctgcata taaaagattt ggagagtact gcggtgttct gaatggaaaa gagagagagt
     7501 aagagaaagg cactagaact ctgaatcagg actgctgaag actttgaaag ggactatgtt
     7561 ggtcttccct acggatggag ggtttcctgc gatcttaacc attcaactgc ctccttccct
     7621 gaaagaattg agccaagatt cagataagat tcttcaggca ggatacagaa caggctgacc
     7681 tgctgtacag acgacttgca ctgcacacag ccccagatcg ctgcacatgc agccagcaac
     7741 aatgcaaaca aacagagatg gctcagaagg cttgggtcct tctccaatta gctcgtgcct
     7801 gcatataaaa gatttggaga gtactgcggt gttctgaatg gaacaagaga gagagtgaga
     7861 gaaaggcact agaactctgg atcagtctct acgtgctgag aaggttcacg gcttagctga
     7921 agtcctgact ataacagtct ggcaggctgg atggctgagc tagctgttct ggaactgtcc
     7981 tggaagcaag gctttagagg aaacagcttc gatgtagtgg aggtaaaatc aagctaggac
     8041 ctagaataga aggtcccaga atctcagcat ctcagaatat gagttttgtc aggactgtct
     8101 ttctcttctt ccattctgca atatacaaac cttacaagca acaaacagct ctgtaaagac
     8161 attcatatag aacatgtaga gtccacagat taaggaagat caataaagac agacaactgc
     8221 atttcaatag aggttagttt gatcacataa tcaaactaac tgttcattca taccatttac
     8281 aggatgatat gtaacaagtc atgagaattt tgaacccaat aagtgttatt ggcagtagat
     8341 agacatttaa gcctcatctg gtcccatctg tctctgtgta cagatatata tacatcacct
     8401 atcttgttga tcttgtcagt cttcctcttg gctgtaagcc aaggttttca agggggtctc
     8461 cctttgtcaa gtctgatcgt tatcaactta gaaggaactc aaagcttttc ttttcctgtg
     8521 gaaatacaga cataatctct ctccagcata accatttcct gctttccatt ctgattttag
     8581 aacttcctta aaataaacag gctggtcagt tcagtccttt ccacaatcca atgtcttaca
     8641 gcagctgttt ttgtccatta gcattttaaa aatgtaaagt tagtaaagtg ctatgtcttt
     8701 atctcctgaa tatgtgacta tagtgtgatg cacatattta actttaccaa actctgtaaa
     8761 atggaacaca atccatttgc caaatttcat ttctttgcgt acttttaggg ttactgcctg
     8821 tagttaatgg agtttggtta tattatgagc aagtaggcca ttgcctcaaa ttctgtgcat
     8881 agagattctt taaacctttg ctgtttgaga tggtgttctt tatggaatgc tgaagcctct
     8941 ggttgataga agatagccac ttcctgtcaa tggctggtta gtttcaggat tgccttgtgc
     9001 ccgagagcct ggcagacctg taagggatct tatgtgtgtg aagacagcag gtgactccta
     9061 ttcctgattg attgttgtag ctgaattatc ctgagtaagt tcagcagtct ctgcgtatat
     9121 tacagaaagg gttttctgca aattgagaat cagctactat atcaagagaa tctggaaaat
     9181 ctgataactc cataagtatt gcatataatt ttaatatttg aactgactta cagggactct
     9241 cagccacctt acatcttctg atttatatcc tgcctttcct gatttactgg catcagtgta
     9301 atatttagtg gcttcaggaa ttggagttct ttttactata ctagggagac tccaattagt
     9361 tctttttata aactaaagtt acttgctttt agggtatttg gtgtcaatct ctccccaaaa
     9421 gttacttcat gctctttgca aacgttcatc ttgtgtccac aatgagtcaa tatctgcctt
     9481 agtaaaaggt accacaatct aagctgaatc cattccagat aattaatgga agtctcattt
     9541 tcccttttag tatcaaatca gaaacctttt ctatgtaggt ttttaatttc ttactctgtt
     9601 tatgtgctaa aattttccat tctgagatat aatcctccct ctgcgagaga attcctgtag
     9661 gggaatgggt agaaggaaag atgactaaga tgcaggccat ctttagataa atacaatgta
     9721 gttgtgtatc ctgcaacttc ctttctacca gagctaactc tttctcagcc tccactgata
     9781 atttcctcag gctatttaaa tctttatcac cttgtaaggt ttgaaataaa tcactcagct
     9841 cttgagttgc caatccaatt gcaggccata gcctgcttat atctcctagt agcttctgga
     9901 aatcattaag agtccttaat tgttttcttc tgttttacac cctttgtggc ctaaactttt
     9961 gtagacttat tctagataat taattaatag aatcccctct ttgtattttt cagggacgat
    10021 ttacagttcc cagcaaagca aggttttttt tttttcttta cttcatcatt ctttccagga
    10081 tatttatgtc tgaatcagcc aataggatat catccatcta ataataaata atggatcgag
    10141 gaaattgttt gccagtcgtc tccagtggct attgtataaa acattgagac aaggcaaggc
    10201 catttccctg gggcaggact ttccaatgat atctttttat tggacaaatt ctattaaagg
    10261 taggtactga ggaaacaaac ctttccttat tatgttcatc tagaggaatt gtgaaaaaaa
    10321 gtcttttaga tcaatcacta tgataggcca ttccttagac aacaaggaag gtgatgggaa
    10381 cccattggct gaataatctt aactgttctg agatctgtca acatcctcca ttttgccaga
    10441 ctttttttaa tgacaaataa gggctggtgg actgctcttt atgctgcttc tggactagct
    10501 gttctagtgc ctgtagtttt tcttttgtca tagaccgttc atcaatccaa ataggttggt
    10561 cagtcaacca ccttagtggt gaggctgttg gtgttttaaa agcagtggat ctttgaagta
    10621 aagctgaatt gtcagcccct gctgggcctt atttttggac agtccgaaac tgtctttaat
    10681 aacattcctt agctaatttg attttttttt tattagaaat ctgactggtt ttgcgtctag
    10741 cctctaaaac tgaagggata ttgactagtg ttttccactg ttgtaacagt tctcttcccc
    10801 ataagtttat ggctatatca ggctatattg aggctatgta tggccttaac tttcctatct
    10861 gaccctcagg ccctgtacat tcaagccatc tggtattttg ctttatttgg gacaaagtac
    10921 caactccttg aaattggatg catacttctt cttgaagtgg ccaatctgca gaccaatgtt
    10981 ttggagagat aatggtgcat ctgccccgtg ttgaccattc cttcaatttc agcttcgttt
    11041 actaatattc caagcttggg cctttgatcc tctatagaag tttgccaaaa tattcatttt
    11101 gggacccctt ataggttttc taaattgttt gtagaatttg cctcagcctt gttatctggt
    11161 ctcaaaactt ctgttttcag agtagtggtg tttaattgtc ttgaggaaaa gaactctctc
    11221 agtctggcat tggggtctgc aagaggaccc tctgggagtc ttttggtaag atgttgtctc
    11281 atttgtctgt cattgctcca cattccctag tccagtgttg ccctttgcca catcttttgc
    11341 atattccaga aagcatagac tcacttttgg gattaatttg attttctctg cagtttattc
    11401 tgaaatgacc ctgttcacca caattaagac attagaaatt ttgggtcatc tcaaggcctc
    11461 tagtggcagt ttctcctact aacgttatat caggcaaatg aggtctaaga tcagctgtaa
    11521 tgtaatccac tcatcaaccg atgccttctg aggtctgatc acttgcattc agcatttgca
    11581 ttttcaaaag ctaaggactc gattagtgcc tttcttgcta atagatccta tatcttccct
    11641 tccacagcag aagttaacgt ttgcaaaaag tcagagaagt tagaccttgc ataacttgga
    11701 aaaaatggtt caagtctttt tcctgtctct gtgactttgt cccagaagtg taaggctgcc
    11761 aagtgacaca aggtcaagtt tcttccatca tagacaccct gcacttctac caggcagctg
    11821 acctttagaa acacctaccc cgtctctttc ctccaccatg ggaaccctca tgaatgtgac
    11881 ccaggttcta ctactgcttt gccaccatag tcttccaggc ttggatcatt ctacttttaa
    11941 tagcccaaga agtcaggact ggttttacaa acagcaaatg tatcccaaaa ttagtgacac
    12001 ttcccttaaa tgtcctcagt tctagcacat ccatgagttg ccattcaagt tcctgataac
    12061 cctgtggatg atcatctggg ggtctttgtt gtacactaac cggataaact aaagtttgtt
    12121 ttctaacgac cttggttgac tttctctaat tttatctttt atctatacct gaatattttc
    12181 cctaaccgat cttttaagtt cctcccttaa ggtctgtgct cttgcttcat agctctgctt
    12241 tggttgttca tcctgttcta taagttcctc cattccctgt tcaaggttct gtttccacat
    12301 cttaattttt ttctctatat cacaattatt ttgattgatt aatttcaaaa ggttctcctc
    12361 caagccttgc ttccaatcct cattatttcc ctctgccact cagtctgatg ggcgagctgt
    12421 tgcatcgttt gttctagtgt ctcttccagc tcctgtctcc aaccttcatt ttcttctctc
    12481 tgtcacctat tgtgacctat caattcctgt ggctttagtt ctagtgtctc ctctcagcca
    12541 tgtcgcccag tcttaaattt cttctgttgt tcatgctgct ctgtaaattc ctgtatcttc
    12601 tgttctaggc cctgcttctg taatttcaat ttctcattat gttgtaattc tattattgta
    12661 taatctacct tctagcttag gaaattatcc tctctactct gctttcaaat tttatctcta
    12721 tctctttgcc attcagtcag atctatgaat ttctagcatc ttttccagtt cctgtctcca
    12781 accttcattt tcttttctct gtcacctatt ttgacctata cattcctgtc cctttagttg
    12841 aagtgtttcc tctaatccct tttctaaggc tcataatgtt tatctagggc cctgtctttt
    12901 gagaagacat gataaataag atagtaaaca ttgtaatgct aactggcaat gtgtccattt
    12961 ccttttaatc catacatgtc aaaccatgca aaatatcatc ctacaaaacc caaaattgta
    13021 tttttaagct ttaagtattt taaaattgta tgtaaatcaa tgtatatata atacttatta
    13081 cctgatccag accttcttgt acctctttct ccctctgctg ttcaaattgg gacactgcag
    13141 ttcacttctg ggctgtcctg cctttgtttg aatcatggct gctgatctga gagcagatct
    13201 gactgtcctg agcctattta gacctggtga agagagggaa ccaggaagca agcacaagaa
    13261 ggttctctgg gccagagatg cgtagatcaa catgctgtgc ctgtgagaag gctacctcac
    13321 aggcagtctc acccagggtc tctgagccct ccctaggctc agggaaccca aaccatgttg
    13381 caacaccagt gctacccaag tcccacctag ggctggggtg ttgcccctgg ctgccatggg
    13441 gctctgggag ggagcctctc agaagctctc tgtagacccc cttagactca ctcagcgttt
    13501 catccacaca ctgctgcagc cctagatcac agcctagcat ttcacactgc acaaagggaa
    13561 cttttttctc aggttagttg ggttctaaac ctatcatcta tctatttgtg gtagtaattt
    13621 ccaatcccat aagcctttat aaaaaatgca caatccatat attatattca tcaactatat
    13681 gcctagattg ggcagatcta aaactatact aacttgattc ctctgctact tgcagtttct
    13741 cctggccatg tgttctatag tttcatgaag tctcatttat taattgtcga tcttagagcc
    13801 tgagccattg gtgttctgtt caggaacttg tctcctgtac aaatgcgtgg gtatttccca
    13861 ctttctcttc tttgaaattc agtgtattca gttctgtgtt gaggtctttg atccacctgg
    13921 acttgagttt tgtgcggggt gatgaatatg gtctattttc actcttctac atgtaggcat
    13981 ccagttagtc cagcaccatt tgttgaagat gctttcattc tttgtaaaat tgttttattt
    14041 acatttcaaa tgttgcctcc ctttcttgtc ccccctcaag acttctttac tccattcccc
    14101 ctcccctttg cctctgagag ggtgctcacc acctcaccac cacacccttt ttcaggggca
    14161 tcaagtttct acaggattag gtgcatcctc tcccactgag gccagacaag gcaatcttgt
    14221 gctacatgtg tgcctagggc catggaccag cccctgcttg ttctttatgg tagcttagtc
    14281 tctgggagtt cccaggggtc caggttagtt gagcattggt cttcatatgg tgtcaatatc
    14341 aaccatcagc tccttcagtc cttgccctaa atgttccata ggggtcccag acctcagtcc
    14401 aatggttgac tgtaagtatc tgcatctgtc tcagttagct gctggtagaa cctctcagag
    14461 gacagtcatg caggagtgca actgactgcg aggtagtttt caggcagaca cagtgagcca
    14521 tctatgcctg agggaacctt tccgtgcttg ctcccccata cgcccaaagt ctacccagga
    14581 catctgacag ccaggcctgc tctccctact gcttgtgctg caggctgcct gaggtcagcg
    14641 cacaggctgc ctgctgaaac ccaaagatag agagccagct cagaagtaca gaagctgcga
    14701 tctttctaca gtcagccact ccctgtgaat aaaagaatct aagaggactg cagtgtcctg
    14761 aattgaacag cagagggaga caaatgtaca aaaggctctg gatcagataa taaggattat
    14821 acattgataa tatatacata cacctaccta aagaatcaca ataaataaca ccttttgggc
    14881 tttatgggat gatattttga acagttcaac agggatggat ttaaaggaaa tagatacctt
    14941 gtcgtttaac acaactgcaa tatttattct cttgatttgc tatgtcttct caaaagacag
    15001 ggccctggat aaaacattat gtgccttaga aaagggatta gagcaaccac tagagaagtt
    15061 catagatgag actgagcaac agagagataa acttaagact tggcaacaca gcctggagga
    15121 aactctagaa ctgaaggcac aggaaattgc aggtcataat aagcaagagg ttggagacag
    15181 gagctggaaa agatactagg aaaaaagata aagaatttca tagatcagat tgaacaacaa
    15241 ggggatagag ataaaatttg gaagcagagt ctaggggttg gggatttggc tcagtggtag
    15301 agcgcttgcc tagcaagcac aaggccctgg gttcagtccc cagctccgaa aaaaaaaaaa
    15361 aaaaaaaaga aagaaaagaa aaggaagcag agtctagaga ataatttact aaagctagta
    15421 aatcaaaata aggtagaggc tgcaacatca gaatgacaac ataagtttta aaatgtggaa
    15481 gaagagctgt gagcagagag caaaggaact cagggaacag gaagaaggga caagaggaga
    15541 gatatgaggc atgggcacag accttaaggg aggaatttaa aatttcaatt aaggaaaata
    15601 ctcaggtaga cacagaagat aaattagaga aagccaacca aggttgttag aaaacaaact
    15661 ttagtttatc tggttatcgt acaacaaaat ccccagatga tcatccacag ggttatcagg
    15721 aactcgaatg gcaatctgtg gatgtggtag aactgaggaa atttaaggaa agagtcacta
    15781 attttgggat gcattcacca tttgtaaaac aaatcctgac ttcttgggct attaaaaaca
    15841 gaatgatcca agcctggaag gctatggcaa gagcagtagt agaacctggg tcacatttac
    15901 aatggttccc atggtagaga gaagagggga aggagacacc acaacaaaat agggccagga
    15961 gcagacgcag caaacattaa gctcctcaga agggagaggt tagggacact gaatgggtaa
    16021 atgtttcagg gaagatctga gaaagtctta ccaggacaat tcgtcagggt ctttgaacat
    16081 ggcctactca tgggagttat gggatttctt tacctggtat gacaaataga gcctggaaat
    16141 agacttatac gcaagtagac tgatattaaa caatcattta ggccttgatc tcgtgaaggt
    16201 tggggcagaa gacagcagaa atgctgtctc agcagttaac atttgttcag actgctttat
    16261 ttgctttggg ttgttttttt tttttttatc aaatgagtgt ggttctgagt ctagtattgt
    16321 acaattcctc tgggagagcg atcaagttaa acatttaatg atttccagtt actggcccaa
    16381 ggacttgttt tattttctct tgttttgttt ttcttttctt ttcttttgtt tggaaggaag
    16441 cctctacgtt ttgacaggaa aggcgaatag gctctgaccc cttctagagt gatatggatc
    16501 agaaaatgca aggggagacc cccctgaaga actagaaaat ttaagagaat caaacaggac
    16561 agttaaagat tctttgcgcc atcctcacat ggcatgaatg aagactcact acaattggtt
    16621 attaataaaa ttaagtcata aaaaagacag ctgtctttct cctgctcaaa caaggagaat
    16681 ttcatcttgc acaatccata caaatatctt agtgatgcta aaaatttggt tgtgagattc
    16741 atatattaca gaatgtacag ctttggtgag attcatcctc agagatgcag aactgacctg
    16801 cctggccccc tgattcagtt gctgttcaaa acagcttcag ggactgccat gggttccagg
    16861 ccaccttgcc tcatccaacc tttcagacaa tccagtcaga acttcagtca agttctgaac
    16921 cttccagata tgcaaagact ggataacaga tgctaaagct agctttctca aatttaacca
    16981 aattttctaa ttttcttacc cttcctcacc cctttaaaga attttttgtc acttctattc
    17041 agcaggaaga agttatagag catcatcaac ccaagtccct tagattgggg tggatggttc
    17101 tggttatttt atgaattata gctatgttgt cattttaagg tatactttac aaatgttata
    17161 gctttggaca gggaggaaac tagagagctt aaactcaggg atttctacct tcttcttctc
    17221 tgtccttcct tcttaggtaa agaaaagagg ggatgaaaaa gaaaagaggg tatatagtaa
    17281 tataaaaatt agaggaataa caaaacattg tatagccata tcttacattg gcagaaatct
    17341 ttataattaa gcaaattgaa gttataagtt tacattggta cagaatttat agactgatgc
    17401 aggtttaagg tttttgttgg tgtgaatttc ttgatacaag atttgaaatt aatactgtta
    17461 ctctttgata ggcattgtac ctatgcaact catctaagaa tacaaggctt agacccagtc
    17521 cttctaatac ctgccattac aaactgttta ggatgaataa gtaacagaag ttaagggcca
    17581 gatagtaaac tcatggttat attagattct aatttaatta taataaatgt ttttaattta
    17641 ctcaaataga aatgactaag aataattaag gtctaagagt tcagatatac ttcgtataaa
    17701 tagtcttcaa aggtgtcaga agtccacaga aaacaacatt taaggccatt tcatttttaa
    17761 agatcatttc actagagaca taccctgata gcaccccttc ttggttcaaa gaagaaattg
    17821 agcatcagtg gagttgttcc agttgtggcg agatagccac taggcaagaa ttgcctcaac
    17881 tcatctatag acaaaaatac tgtccaggaa aaaggcacag tatgcaaaat agtcgactga
    17941 tagctctgcc aatacagggt aagcagtcct tcctaattct gctttacaaa ggtcatcaga
    18001 tgatcctggc cagagggctg aaggctgatg ctccaacgtt ttaaggaatg agggactgtc
    18061 caggtagtca acatctctac aaattggtta agtcttggaa gctatgtttt gtgcttccta
    18121 tattttcaag taatatttaa attgttctca gatttctgac agaggtgaag actggtcata
    18181 gtctcataga caactcaagc tatttagcat tgagaaaaat gatatagatt tgagaggatg
    18241 attttcagat gataatacaa gctgaaacta ggacataatt catgtataga attgcaagct
    18301 ttttaagcta ggatgataga gtgctttatc taaattgaca aatatgatgg actgagtgtt
    18361 cctatacttt ataatttact aattgtaaat tataagttgt gctcaattta tatcttcaaa
    18421 aaaggaacct tttaactgga cagaaagaga gaaatgttgt gggttaccct ggtgctgttt
    18481 gtattctgat gttaattctg cttcctcaag aggacctgcc ctgacaagga gtggatacca
    18541 tactcaggtc atttcatgtg aaccttttcc ccatttaaac tggtcaagta aaggctagac
    18601 ccgtgattgg gcagtggaag gaaaaagatg gagctggagg ttttagagag gtgtcggggg
    18661 agaagggaag gagagagaaa gaggaggtag aaggaagatg gaacaaaacc acatggcccc
    18721 gagaagcctc aagtagcaag ggatctcata gctgaggaat agagtagtat agtggtaaat
    18781 ctgcccaatc taagggcact gggttgtgtg tttttacacg ggtttttgga gttgaagatt
    18841 tactgcagtg cccatcccat gggcaagcat caatccctaa cactattaat gatactctgt
    18901 tttgcttgta gacagagaat gttgtcctct ttgagaaacc cccccttcac ccctagcagc
    18961 tgactcagac agatacagtg gatgaagctt tggaactctt atggaagaat aggaggaagg
    19021 atttcgagct ccaaagggga taggagttcc acaggaaggc cgacagagtc aacaaacttg
    19081 gatccttggt gctttcagag tctgaagcac catccaaaga gcacacccaa gctgcactta
    19141 ggcctcccca ctcacatgta gcaatcatgc agcttgatca tcatgtgggt tctgaacaac
    19201 aggaacaggg gctattttaa aagctgttgc ctggaaagga ttgaaggagt tgaaggggat
    19261 ggcataagaa caacaacagt atcaactaac ctggatccct gggcgctccc agaaactgaa
    19321 ctaacaatca aagatataca ctggttaata aggctatcag catatatgta acagaggacc
    19381 accttgtctg gcctcaatgg gaaagtatgc acaatctggc ctcagtggga gataatcttc
    19441 ttgtgcactc tgtacagatt gtctctattg tttcaagtgt tgatttctgg accagcagaa
    19501 tgctttctga actgttattt ttatgaagca tcacctatct cgttgttttc taaacattct
    19561 tctgcagcac attctgactt gtttaataaa gagctgatgg cctatatcag agcaggagag
    19621 agaaaatgga acatcagaaa agagagagga actctaggaa ggagtcaggt ggagggattc
    19681 accagtcaaa cacagaggaa ggagcaggtg ccagaactga aggggagaga acgtgataca
    19741 tggcagaact tagattagaa aattaattaa aagaaggtta attaaattat acaagccagt
    19801 taggaacaag cctaagctaa ggcctgagat taataagtct gtcattattg gaagaggtca
    19861 ggttgagaca gtctggtggt actcttgagc tgaagggctt cgcttagagg aaatcagcaa
    19921 gcagtttttc tttttttatg gagacttcct ttttggcaaa tcatagaagc cttgttagag
    19981 ttagcatttt gtgaccattt cctgcctggt ttctcgactc tggctgcaca gtactccatc
    20041 taatgaatgg ggagaacctg atgtggtttg tatatccctg ttcaggccag agacatccca
    20101 ttgccctctc gttctttctg gttagatagt acaaacttgg agtcatgtag atgccctggt
    20161 aagaccaggg ggagcttagt tcaatagagt tccaaaggct aggaactgta aggtattctg
    20221 tgagattagg ggcaaaagct aaagatttgg atagacccag catgagattt gggaactggg
    20281 gaagactcag agccacccag cctttgatgg gtgcctagca tctggatggt acaagaaaga
    20341 attgttaaat gtcattgtcc gtgtactcta ttgtcattgg ctctgttttc tgttgttgct
    20401 tgggccttat gtcttgtgtg tctggtctat cttcatgttt ctgacttgag atggtatgga
    20461 aaccttgcac ccataagcca ggcaccaatg attccacccc acctcctacc ctgggtctag
    20521 ttggaatgag gtcggatcat gctatctgca agctgctttt ggaaaagtca ctcccaatat
    20581 ggagttttga gggagtagga tttgcttgga acctgtaggc ttagattttt tttttcaaaa
    20641 cctactttaa ttagggttct ttaacccttc aatatcgggt tggggattta gctcagtggt
    20701 agagcgcttg cctagcaagc acaaggtcct gggttcagtc ctcagctcca gaaaaaaaaa
    20761 aagtcacaaa cccttcaata tcccttctag cggacctacc agaggtaggg ggaaagaaag
    20821 gttaatagga aacagaggtc gtagacctgt ttagaagtaa ccctttgggg gatatcccag
    20881 tctttgttgt caggatataa gcagcccagt ccaaaacatc aaacgtcagt cggtagtggc
    20941 aatgcagtct aattggcaaa caccaaacat gaatcagtag cagcagctca atccagccga
    21001 aatagcatga aaagtttttg gcaagtttct atgaagtcac aagcaaaggt ccttgacttg
    21061 gtacaaagca aaccaataca agagcctggt ctctctgtta tatttgtatt ctttctaatc
    21121 atcacgtgtc ctttcatgtg tctgcctcaa caacacattc cttcacctat ctacttcagc
    21181 aaaacagcct ctcacctgtc tgcttcagca aaacatcaca tgacataact gagtctccaa
    21241 agaaaccagg aacttccact ttagggacca gtggttattg tttaaaaacc cagagtccca
    21301 tgaggaaaac agcggccaat cctattacag caccactgtc cctgagaaaa tgggattcag
    21361 cagctgtgag gagcgcctac gctgaaattc cagcactgga ggaggactac ttaacaaaca
    21421 aactgcaacc aatggcatca accaccaatc taccaacctg tgcctcctgc atcaaggcca
    21481 taacatttat atatctataa ataaaactat tattcatctg atgtaattgt cttctcagag
    21541 gtttacacca aatttgaaga acgtattcta cctctttggg tggtcccagg aaattgttgc
    21601 tttctgtctc atgtctcctg tcctctgcaa catttttgtc agataacctc tgcgttctgc
    21661 aatgtgggtt ggttttcatt tttctccaat catgttaggt tttccctcca accacaatga
    21721 gtgccagaag caaaagtatc ttttattcac atgatataat tgtcatcttc aaggcttact
    21781 gcttccacct gctaatctag gcctagtcct ggaggtttct agtctccata caatctaatc
    21841 taggcctaga atgttttcag ccttgagact tgttgctgag taaacttact ccttctagct
    21901 ctttctgaac tctggctgac tattcaactt agttgttctg gcccaaactc ctctctaagc
    21961 tctctatttg gcttctctct acttcttgta tattactctg tttgttctca tactaacttt
    22021 ataatctgtt ctaatcttct ggttccttct cattccttaa cccatttgtc ttcacctgtt
    22081 tttagctttt tcacgttctg caaccttaca actgttctta caacttgact cttacacttt
    22141 gtctcttaca aacaccctga taaaactgcc ctctcccttt ctgcactgag atcttttctc
    22201 tttgttcttg tgagaactga gcatctattc tgtcaaatct ttctttgact cattactttg
    22261 tctgccactc aattatgtaa ggaagcatga gtgcttcctt ctacatatta actttaccct
    22321 cattgtttgg attaaaggta tatattaaaa gcgtctctgt attccatcaa aagggattaa
    22381 aggtatggac taagactgag ccgcaccaca actagaaaca agttttccag taagaggtac
    22441 agtctcaagg ttgacagtgt gatcaaatat cctgcaacat cctcagacca gcaagaacct
    22501 tggtcctctg gaaagggcct ctgtcaccac tgaaacttaa agaaggcctt agattgcagt
    22561 ggatatattg gagaaggcct aaagttgcag ttagaagttt taaaataaat tgtgctccag
    22621 tgaggaccaa agaaagacct aagatcttca ctagattttg agaagacctt tgacttaagt
    22681 gaaaacctag agaaggactt gggccccaat gattatctgc agaaaaattt aggcgaaatt
    22741 ctccaaacat agtaaaaaac tgttgatgac tttgtagaac ctgtgaggac tttgggctat
    22801 ttgggggcaa taatgattct tgggtactga cttatcctac agtgattaaa ctagactcca
    22861 gtgagtactt gcaggaggcc atggacacca ggaataatca tggcaagtct caggctcaga
    22921 gagaatctgg aaaagtcctc agtcatcaat gagactttgg agaaatgcct tagattggca
    22981 ttgagtacct ggagaaagcc tcaaggcaca gaagggttag aatgttttgt gctctagaga
    23041 ggaccaaggt aaggctgaaa gtcttcacaa gactgttgta aagacccttg acttaaatga
    23101 gaatctggag aaggctctaa gttctgttta gaaaggttag aaagctttgt gctccagtga
    23161 gaccctgaga aagacctcag gtcctaggga taatatacaa aaggcctaag atctcagcaa
    23221 ggacctgaag gtttcccttc tgcccaaatg ggaagctgat gaaagttgta agagacagaa
    23281 cataaggaag gcattcagaa ctaatgaagg cctgatggag gccttagaga acctgtgaga
    23341 ctagggcaat tttttaggcc cagtgagacc ctggataatg ctttaggatc cattgagaaa
    23401 tgaagaccca aggagaacat ggagaaggct ttagacatca gtgactatct aagagaacct
    23461 caaatctgag tgagcatgta aagaacttaa aaccaaatga taatctggga aaggccttat
    23521 taggctccag gcagagccta ataagaatat atagaaaact tgatgagaat atatagaaaa
    23581 tctgatgcct actgtagttc ctggataatg ccttcatacc aaggaaaaat tttaggtgct
    23641 ggaccattgt gagaatctct ggtaggccta atgccttgtt gtgacttgca aaggccttag
    23701 atccaagtca taaggcagag aaggtcttta gtcacagaaa gaacttgttg aggcttaagt
    23761 ccaggtgaga aacaggcctt ggggtccaag aaaaacttgg gtaaaaattt aagacccaga
    23821 gagaatatgg gcaattcttt aaagttctta aaaaacctgg gaagactttt gcctattata
    23881 ataatatccc aagaaactcc ttacacacca caagaatctg gaaacatctt tatctccact
    23941 tataccctgg aaagggatta gactcaagtg atagcatgtg gtagcccttg gatcccaatg
    24001 agaacctgag gaatccctta gtcttcactg aaactttggg taaggcctta ggtcactgtc
    24061 agaaccttga gaatccataa gttccaatga gaatgtggta gtttcttggc tccaaattct
    24121 gggctccagt aactacctag gaacgatgta aactctgagg agactttgca gaaggtctta
    24181 gataccagtc agagcctaaa gaaggttctt ggtcccagtg agaatattca gaaagtttta
    24241 ggtcacagtg agaactagga aaaattcttc agatacattg caaacacaga gatgacttta
    24301 tagaacctgt aaggtgttgg gaatattttt aggccacagt acatcctttg gtcatttctt
    24361 aatatacaga gagaacctag acaagacttt aagaccctgc aacagactca gaagctccta
    24421 ggccccagtg acaaagaatg ccctagatac cagaaacaat ccagaaaacc ttaagaccca
    24481 ttgagtatct gggaaagtct caatgagact ttgaagaagg ccttagatta cagtgagtac
    24541 ctggagtacc ttaagttcca gtaaaacata ttagaatgtt tttggctcca gtgagaacct
    24601 gggaaaggcc tgagttctca aatagacttt ggggaagtcc tttgaatacc atgaaatcat
    24661 agaggaggtt ttaagtccca ttgagatcct gcagaaagtt ttaggccaca gcaagaatat
    24721 gtggaaggtc tccagactct gtcaaaaccc atcaaagacc ttattgaatt tttgagaact
    24781 tgtacaaatt ttgggcctag tgagaactgg ttaatgcctt agacgctcat gagaatctgg
    24841 ataaggattt gagacagtca taacatgggg aaagtcttgg tcctgagtta atactggatg
    24901 gttttaggtc ccagtgactt cctggaaagg cattaggata cactcataac ttctgaaagc
    24961 cataggctcc tgtgagtaca ctgtaaaact ttaagaccca atgaaaatat gttaaaagtc
    25021 tgttaccatt gagtagctga ggaatcccat aagctctagt ggaaacctgt aaaaagaaat
    25081 ttaggccaca gtgagaacct gttcaagacc taaggcttca atgaatcttt ggataagtcc
    25141 ttagacccaa ataagaacct gcaaacagtc tttagtccaa ttgagaagct acagattcag
    25201 taagaacctg gagaactcct tagactctga ggtcctgagt tcaaatccca gcaaccacat
    25261 ggaggctcac aaccgtccgt cgtgagatct gatgccctct tgtggtcatt gttccaacat
    25321 ggccctgtgg atccgcttcc tgcccctgct ggccctgctc atcctctggg agccccgccc
    25381 tgcccaggct tttgtcaaac agcacctttg tggttctcac ttggtggaag ctctctacct
    25441 ggtgtgtggg gagcgtggat tcttctacac acccatgtcc cgccgcgaag tggaggaccc
    25501 acaagtggca caactggagc tgggtggagg cccgggggca ggtgaccttc agaccttggc
    25561 actggaggtg gcccggcaga agcgcggcat cgtggatcag tgctgcacca gcatctgctc
    25621 tctctaccaa ctggagaact actgcaacta ggcccaccac taccctgtcc acccctctgc
    25681 aatgaataaa acctttgaaa gagcactaca a
//
