LOCUS       NM_001108923            2825 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus inositol polyphosphate-5-phosphatase A (Inpp5a),
            mRNA.
ACCESSION   NM_001108923 XM_001058238 XM_344971
VERSION     NM_001108923.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2825)
  AUTHORS   Auethavekiat,V., Abrams,C.S. and Majerus,P.W.
  TITLE     Phosphorylation of platelet pleckstrin activates inositol
            polyphosphate 5-phosphatase I
  JOURNAL   J Biol Chem 272 (3), 1786-1790 (1997)
   PUBMED   8999861
REFERENCE   2  (bases 1 to 2825)
  AUTHORS   De Smedt,F., Boom,A., Pesesse,X., Schiffmann,S.N. and Erneux,C.
  TITLE     Post-translational modification of human brain type I
            inositol-1,4,5-trisphosphate 5-phosphatase by farnesylation
  JOURNAL   J Biol Chem 271 (17), 10419-10424 (1996)
   PUBMED   8626616
REFERENCE   3  (bases 1 to 2825)
  AUTHORS   Laxminarayan,K.M., Chan,B.K., Tetaz,T., Bird,P.I. and Mitchell,C.A.
  TITLE     Characterization of a cDNA encoding the 43-kDa membrane-associated
            inositol-polyphosphate 5-phosphatase
  JOURNAL   J Biol Chem 269 (25), 17305-17310 (1994)
   PUBMED   8006039
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Mar 4, 2011 this sequence version replaced NM_001108923.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582416.877509.1,
                                           SRR22582419.2764128.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-357               JAXUCZ010000001.1  203619983-203620339
            358-399             JAXUCZ010000001.1  203681956-203681997
            400-500             JAXUCZ010000001.1  203715235-203715335
            501-588             JAXUCZ010000001.1  203719432-203719519
            589-652             JAXUCZ010000001.1  203747820-203747883
            653-756             JAXUCZ010000001.1  203754138-203754241
            757-809             JAXUCZ010000001.1  203759349-203759401
            810-929             JAXUCZ010000001.1  203760749-203760868
            930-1014            JAXUCZ010000001.1  203773381-203773465
            1015-1110           JAXUCZ010000001.1  203788552-203788647
            1111-1185           JAXUCZ010000001.1  203788743-203788817
            1186-1259           JAXUCZ010000001.1  203797425-203797498
            1260-1371           JAXUCZ010000001.1  203805281-203805392
            1372-1440           JAXUCZ010000001.1  203807725-203807793
            1441-1528           JAXUCZ010000001.1  203808567-203808654
            1529-2825           JAXUCZ010000001.1  203808739-203810035
FEATURES             Location/Qualifiers
     source          1..2825
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..2825
                     /gene="Inpp5a"
                     /note="inositol polyphosphate-5-phosphatase A"
                     /db_xref="GeneID:365382"
                     /db_xref="RGD:1306168"
     exon            1..357
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     CDS             283..1521
                     /gene="Inpp5a"
                     /EC_number="3.1.3.56"
                     /note="type I inositol 1,4,5-trisphosphate 5-phosphatase;
                     5PTase; type I inositol 1,4,5-trisphosphate
                     5-phosphatase-like"
                     /codon_start=1
                     /product="inositol polyphosphate-5-phosphatase A"
                     /protein_id="NP_001102393.1"
                     /db_xref="GeneID:365382"
                     /db_xref="RGD:1306168"
                     /translation="MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVLHTH
                     KPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEHFT
                     ALGSFYFLHESLKNIYQFDFKAKKYKKVTGKEIYSDTLESTPMLEKEKFPQDYFPECK
                     WSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPSVYSGVRHKALGYVLDRII
                     DQRFEKVSYFVFGDFNFRLDSKSVVETLCTKATMQTVRAADTNEVVKLIFRESDNDRK
                     VVLQLEKKLFDYFNQDVFRDNNGTALLEFDKELSVFKDRLYELDISFPPSYPYSEDSS
                     QGEQYMNTRCPAWCDRILMSLSAKELVLKSESEEKVATYDHIGPNVCMGDHKPVFLAF
                     RIAPGAGKPHAHVHKCCVVQ"
     exon            358..399
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            400..500
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            501..588
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            589..652
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            653..756
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            757..809
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            810..929
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1014
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1110
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1185
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1259
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            1260..1371
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            1372..1440
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            1441..1528
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
     exon            1529..2825
                     /gene="Inpp5a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggcggcggc tgcgggaact ttcccggcgg gtctaatggc tgcgcgcggg ccgctgtgag
       61 gcgcggcggc gagcgggcgc ggggccgcgg agcaacgaag agccagcgac cgcaaggctg
      121 gagtcccggc caggcccggt ccgacccgcc aagcccgcga tgcgccccag tgctgtccct
      181 cggcgcagct gacgccccgc ggccccgcga gaccccagcc ctaccggccc cgcaggaagc
      241 ggccgccgcc acccagtcca gagcccgctc cgcccgggca ccatggcggg gaaggcggcc
      301 gcccccggca ccgcggtcct gctggtcacg gccaacgtgg gctcgctctt cgacgaccca
      361 gaaaacctgc agaagaactg gcttcgggaa ttttaccagg tcctgcacac acacaagcct
      421 cacttcatgg ccttgcactg ccaagaattc ggagggaaaa actatgaggc ctccatgtct
      481 catgtggaca aatttgtcaa ggaactactg tccagtgatg caatgaaaga atacaacagg
      541 gctcgtgtct acctggatga aaactacaag tcccaggagc acttcacggc actaggaagc
      601 ttttattttc ttcatgaatc cttaaaaaac atctaccagt ttgactttaa agctaagaag
      661 tataaaaaag tcactggcaa ggagatctat tcggacactt tggagagcac acccatgctg
      721 gagaaggaga agttcccaca ggactacttt cccgagtgca aatggtcaag aaaaggcttc
      781 atcaggacgc ggtggtgcat tgctgactgt gccttcgact tggtgaacat ccatcttttt
      841 catgatgcat ccaacttagt ggcctgggag acaagcccct ctgtgtactc gggtgtcagg
      901 cacaaggctc tgggctatgt gctcgacaga atcatcgacc agcgatttga aaaagtttcc
      961 tactttgtct tcggtgattt caacttccgc ctggattcca agtctgttgt agagacactt
     1021 tgcacaaagg ccacaatgca gacagtccgg gctgctgata ccaatgaagt tgtaaagttg
     1081 atatttcggg agtcagacaa tgaccgtaag gtcgtgctcc agttggaaaa gaagctcttc
     1141 gactacttca accaggacgt cttccgggac aacaatggca ctgcgctctt ggaatttgac
     1201 aaggagttgt ctgtctttaa ggacagactg tatgaactgg acatctcatt cccccccagc
     1261 tacccgtaca gtgaggactc cagccaggga gaacagtaca tgaacacgag atgccccgct
     1321 tggtgtgatc gaatcctcat gtccttgtct gccaaggagc tggttcttaa gtcagagagc
     1381 gaggagaagg ttgccaccta cgaccacatc gggcctaacg tctgcatggg agaccacaag
     1441 ccggtgttcc tggccttccg aatcgcaccc ggggcaggta aacctcacgc ccatgtacac
     1501 aagtgttgtg tcgtgcagtg acgtggtggg aagaggtgcc agcgccatga gaggatcctc
     1561 gagagacctc cctgtagcag tgtatcgaac tcatcctcct aacagctgca tcggaaccgc
     1621 ccaagcatca cctgctagaa ggccggcccc acacttcgct tcagcctccg gacctccgga
     1681 aagcctcaca tacctcactg tcgtgtctgt cacgtgacat tgtagacata ttgggtttaa
     1741 tcaagccaca gtcctattgc caaaactcta acagacagca gagcgcctgt attttagact
     1801 tcacagtttt ccatttttaa tgattgtctg tggaggaagc ttctccattt agagccccag
     1861 gtgtccagcg tccctctctg ccaggaggaa tgtgccgggc actagcccag gcagcaagac
     1921 tgccctgtgc tcaagcccga ggccccgagg tctgactctc ctgccatgtt acgtggcgtg
     1981 agaatcacac tgcagctgct ttccattttt atatataaat acatataaat atatactttt
     2041 taaaaataat ttataaatct taccaaaact tatgctgaat atactttcca gtatgagtgc
     2101 acgagtgtcc tgagcaggca gaaccgcagt ctagttgaat ggcgagtcca tcagcagtca
     2161 gcacctgttc ctgagacaag acctagcact tgcccagggc gaggggccct gtggtatgcc
     2221 tggactagca gcttgtcact cttctgcctt tttctgtgta atattaagaa ctgaatgtga
     2281 agtttatagc tagcctgggt gtacctttta agaattttgt aaaccgtttt gtctgtcttt
     2341 tgttaccgtt ttatggtgcc aagtagccta cattaaaacc ataatcttgt gggagaatta
     2401 gaagtagcct cgtccacttc ccacagattg cttctagcat gggctgtgtg taaacccggc
     2461 agaaaagcga cggtgatgct gggcacagcc tgtgccggac tcgcacccag cactgagaac
     2521 cgcggaaggt gcctgcggag cctgctgagg aaacacagcg tgcttttatt gatttacttc
     2581 tgaacactac agttcctgga tggggcggag gcgcgagtta acgtcggttt ccctagaaat
     2641 cactcaaggc cagcctgtgt ccttgatgcc agggtcgggt ctgtgactgc catggtcgct
     2701 gcttgccaat gtgccatgtc cgaagcggtt gtcctccgtg ggttccagct gtgggtcctt
     2761 ccttcgaagg cctctggaag tgactgctcg gttcctaagc aataaaattg atcatggtga
     2821 aaaca
//
