LOCUS       NM_001261404            6197 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus INO80 complex ATPase subunit (Ino80), mRNA.
ACCESSION   NM_001261404 XM_001080838 XM_039104548 XM_230473
VERSION     NM_001261404.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6197)
  AUTHORS   Miura,R., Mimura,I., Saigusa,H., Yamazaki,T., Tanemoto,F.,
            Kurata,Y., Sato,D., Tanaka,T. and Nangaku,M.
  TITLE     Chromatin remodeling factor, INO80, inhibits PMAIP1 in renal
            tubular cells via exchange of histone variant H2A.Z. for H2A
  JOURNAL   Sci Rep 13 (1), 13235 (2023)
   PUBMED   37580530
  REMARK    GeneRIF: Chromatin remodeling factor, INO80, inhibits PMAIP1 in
            renal tubular cells via exchange of histone variant H2A.Z. for H2A.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6197)
  AUTHORS   Chen,L., Cai,Y., Jin,J., Florens,L., Swanson,S.K., Washburn,M.P.,
            Conaway,J.W. and Conaway,R.C.
  TITLE     Subunit organization of the human INO80 chromatin remodeling
            complex: an evolutionarily conserved core complex catalyzes
            ATP-dependent nucleosome remodeling
  JOURNAL   J Biol Chem 286 (13), 11283-11289 (2011)
   PUBMED   21303910
REFERENCE   3  (bases 1 to 6197)
  AUTHORS   Park,E.J., Hur,S.K. and Kwon,J.
  TITLE     Human INO80 chromatin-remodelling complex contributes to DNA
            double-strand break repair via the expression of Rad54B and XRCC3
            genes
  JOURNAL   Biochem J 431 (2), 179-187 (2010)
   PUBMED   20687897
REFERENCE   4  (bases 1 to 6197)
  AUTHORS   Jiang,Y., Wang,X., Bao,S., Guo,R., Johnson,D.G., Shen,X. and Li,L.
  TITLE     INO80 chromatin remodeling complex promotes the removal of UV
            lesions by the nucleotide excision repair pathway
  JOURNAL   Proc Natl Acad Sci U S A 107 (40), 17274-17279 (2010)
   PUBMED   20855601
REFERENCE   5  (bases 1 to 6197)
  AUTHORS   Hur,S.K., Park,E.J., Han,J.E., Kim,Y.A., Kim,J.D., Kang,D. and
            Kwon,J.
  TITLE     Roles of human INO80 chromatin remodeling enzyme in DNA replication
            and chromosome segregation suppress genome instability
  JOURNAL   Cell Mol Life Sci 67 (13), 2283-2296 (2010)
   PUBMED   20237820
REFERENCE   6  (bases 1 to 6197)
  AUTHORS   Watanabe,S. and Peterson,C.L.
  TITLE     The INO80 family of chromatin-remodeling enzymes: regulators of
            histone variant dynamics
  JOURNAL   Cold Spring Harb Symp Quant Biol 75, 35-42 (2010)
   PUBMED   21502417
  REMARK    Review article
REFERENCE   7  (bases 1 to 6197)
  AUTHORS   Wu,S., Shi,Y., Mulligan,P., Gay,F., Landry,J., Liu,H., Lu,J.,
            Qi,H.H., Wang,W., Nickoloff,J.A., Wu,C. and Shi,Y.
  TITLE     A YY1-INO80 complex regulates genomic stability through homologous
            recombination-based repair
  JOURNAL   Nat Struct Mol Biol 14 (12), 1165-1172 (2007)
   PUBMED   18026119
REFERENCE   8  (bases 1 to 6197)
  AUTHORS   Bakshi,R., Mehta,A.K., Sharma,R., Maiti,S., Pasha,S. and
            Brahmachari,V.
  TITLE     Characterization of a human SWI2/SNF2 like protein hINO80:
            demonstration of catalytic and DNA binding activity
  JOURNAL   Biochem Biophys Res Commun 339 (1), 313-320 (2006)
   PUBMED   16298340
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000003.1.
            
            On or before Mar 3, 2021 this sequence version replaced
            XM_039104548.1, NM_001261404.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR26360176.725163.1 [ECO:0000331]
            RNAseq introns       :: mixed sample support SAMEA5760383,
                                    SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-137               JAXUCZ010000003.1  126919396-126919532 c
            138-323             JAXUCZ010000003.1  126902039-126902224 c
            324-493             JAXUCZ010000003.1  126901358-126901527 c
            494-561             JAXUCZ010000003.1  126901157-126901224 c
            562-723             JAXUCZ010000003.1  126898970-126899131 c
            724-844             JAXUCZ010000003.1  126896281-126896401 c
            845-1059            JAXUCZ010000003.1  126894959-126895173 c
            1060-1113           JAXUCZ010000003.1  126893146-126893199 c
            1114-1317           JAXUCZ010000003.1  126891621-126891824 c
            1318-1513           JAXUCZ010000003.1  126890333-126890528 c
            1514-1581           JAXUCZ010000003.1  126889056-126889123 c
            1582-1791           JAXUCZ010000003.1  126887086-126887295 c
            1792-1872           JAXUCZ010000003.1  126886313-126886393 c
            1873-1968           JAXUCZ010000003.1  126885391-126885486 c
            1969-2028           JAXUCZ010000003.1  126881075-126881134 c
            2029-2171           JAXUCZ010000003.1  126879949-126880091 c
            2172-2256           JAXUCZ010000003.1  126878622-126878706 c
            2257-2374           JAXUCZ010000003.1  126877656-126877773 c
            2375-2460           JAXUCZ010000003.1  126875015-126875100 c
            2461-2628           JAXUCZ010000003.1  126873793-126873960 c
            2629-2762           JAXUCZ010000003.1  126873480-126873613 c
            2763-2830           JAXUCZ010000003.1  126872527-126872594 c
            2831-2924           JAXUCZ010000003.1  126872131-126872224 c
            2925-3096           JAXUCZ010000003.1  126870893-126871064 c
            3097-3237           JAXUCZ010000003.1  126864211-126864351 c
            3238-3463           JAXUCZ010000003.1  126858434-126858659 c
            3464-3591           JAXUCZ010000003.1  126852926-126853053 c
            3592-3686           JAXUCZ010000003.1  126848707-126848801 c
            3687-3759           JAXUCZ010000003.1  126840065-126840137 c
            3760-3918           JAXUCZ010000003.1  126832452-126832610 c
            3919-4021           JAXUCZ010000003.1  126831937-126832039 c
            4022-4110           JAXUCZ010000003.1  126831254-126831342 c
            4111-4266           JAXUCZ010000003.1  126828958-126829113 c
            4267-4426           JAXUCZ010000003.1  126828531-126828690 c
            4427-4642           JAXUCZ010000003.1  126826434-126826649 c
            4643-6197           JAXUCZ010000003.1  126822280-126823834 c
FEATURES             Location/Qualifiers
     source          1..6197
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q35"
     gene            1..6197
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /note="INO80 complex ATPase subunit"
                     /db_xref="GeneID:296084"
                     /db_xref="RGD:1310969"
     exon            1..137
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            138..323
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     CDS             181..4860
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /EC_number="3.6.4.12"
                     /note="INO80 complex homolog 1; putative DNA helicase
                     INO80 complex homolog 1; INO80 homolog; INO80 complex
                     subunit"
                     /codon_start=1
                     /product="chromatin-remodeling ATPase INO80"
                     /protein_id="NP_001248333.1"
                     /db_xref="GeneID:296084"
                     /db_xref="RGD:1310969"
                     /translation="MASELGAGDDGSCTELAKPLYLQYLERALRLDHFLRQTSAIFNR
                     NISSDDSEDGLDDNNPLLPESGDPLIQVKEEPPNSLLGETSGASSSGLLNPYSLNGVL
                     QSESKSDKGNLYNFSKLKKSRKWLKSILLSDESSEADSQSEDNDDEEEELSLSREELH
                     NMLRLHKYKKLHQNKYSKDKELQQYQYYSAGLLSTCDPFYEQQRHLLGPKKKKFKEDK
                     KLKAKLKKVKKKRRRDEEFSSEESPRHHHHQTKVFAKFSHDAPPPGTKKKHLSIEQLN
                     ARRRKVWLSIVKKELPKANKQKSSARNLFLTNSRKLAHQCMKEVRRAALQAQKNCKET
                     LPRARRLTKEMLLYWKKYEKVEKEHRKRAEKEALEQRKLDEEMREAKRQQRKLNFLIT
                     QTELYAHFMSRKRDMGHDGIQEEILRKLEDSSTQRQIDIGGGVVVNITQEDYDSNHFK
                     AQALKNAENAYHIHQARTRSFDEDAKESRAAALRAADKSGSGFGESYSLANPSIRAGE
                     DIPQPTIFNGKLKGYQLKGMNWLANLYEQGINGILADEMGLGKTVQSIALLAHLAERE
                     NIWGPFLIISPASTLNNWHQEFTRFVPKFKVLPYWGNPHDRKVIRRFWSQKTLYTQDA
                     PFHVVITSYQLVVQDVKYFQRVKWQYMVLDEAQALKSSSSVRWKILLQFQCRNRLLLT
                     GTPIQNTMAELWALLHFIMPTLFDSHEEFNEWFSKDIESHAENKSAIDENQLSRLHMI
                     LKPFMLRRIKKDVENELSDKIEILMYCQLTSRQKLLYQALKNKISIEDLLQSSMGSTQ
                     QAQNTTSSLMNLVMQFRKVCNHPELFERQETWSPFHISLKPYEISKFIYRHGQIRVFN
                     HSRDRWLKVLLSPFAPDYIQQSLFHRKGINEGSCFSFLRFIDVSPAEMANLMLQGLLA
                     RWLALFLSLKASYRLHQLRSWGEPDGESHQRYLRNKDFLLGVDFPLSFPNLCSCPLLK
                     SLVFSSHCKAVSGYSDQVVHQWRSATSSLRCCLLTELPSFLCVASPRVTAVPLDSYCN
                     DRSAEYERGVLKEGGSLAAKQCLLNGAPELATDWLNRRSQFFPEPAGGLLSIRPQNGW
                     SFIRIPGKESLITDSGKLYALDILLTRLKSQGHRVLIYSQMTRMIDLLEEYMVYRKHT
                     YMRLDGSSKISERRDMVADFQTRNDIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPT
                     VDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAKEKSEIQRMVISGGNFKPDTL
                     KPKEVVSLLLDDEELEKKLRLRQEEKRQQEESNRVKERKRKREKYAEKKKKEDELDGK
                     RRKEGVNLVIPFVPAADNSNLSADGDDSFISVDSAMPSPFSEISISSELHTGSIPPDE
                     SSSDMLVIVDDPASSAPQSRATNSPASITGSVSDTVNGISIQEVPAAGRGHSARSRGR
                     PKGSGSTAKGAGKGRSRKSTAGSAAAMAGAKAGAAAASAAAYAAYGYNVSKGISASSP
                     LQTSIVRPAGLADFGPSSASSPLSSPLNKGNNIPGTPKSLHMTSSLASDPLIRKQGKG
                     TNPSGGR"
     exon            324..493
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            494..561
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            562..723
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            724..844
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            845..1059
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1113
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1317
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            1318..1513
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1581
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            1582..1791
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            1792..1872
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            1873..1968
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            1969..2028
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            2029..2171
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            2172..2256
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            2257..2374
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            2375..2460
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            2461..2628
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            2629..2762
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            2763..2830
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            2831..2924
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            2925..3096
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            3097..3237
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            3238..3463
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            3464..3591
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            3592..3686
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            3687..3759
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            3760..3918
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            3919..4021
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            4022..4110
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            4111..4266
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            4267..4426
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            4427..4642
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
     exon            4643..6197
                     /gene="Ino80"
                     /gene_synonym="Inoc1; RGD1310969"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caacgcagtc accgtccctc ggcctcagag agcgaaccgc ggctccacag tcggcggggc
       61 gacccccccc tccggacccc gcccgcaccc cgccccccct ccgccgccgc cgcggcggcg
      121 gggcccctcg gcccgagctg tgcagttgga ggtcctcgtg catgaagaca gatttgttct
      181 atggcctcgg agttgggtgc cggggacgat ggcagctgca ctgagctggc aaagcccctt
      241 tatcttcagt acctggagag ggccttgcgg ttggaccatt ttctgcgaca gacatcagcc
      301 atcttcaaca ggaatatttc tagtgatgac agtgaagatg gactggatga caataatccc
      361 ttattgcccg agtctgggga tcccttaata caagtaaaag aagaaccacc aaattcattg
      421 cttggcgaaa cttctggagc aagcagttct gggttgttga acccatattc actgaacgga
      481 gttctgcagt cagaatcaaa atctgacaag gggaatttat ataacttctc taagttgaag
      541 aaaagcagaa agtggctaaa gagcattctt ttaagtgatg agtccagtga ggcagattct
      601 cagagtgaag acaatgatga tgaagaagaa gaactcagtc tcagcagaga agaacttcac
      661 aacatgcttc gattacacaa atataagaaa cttcaccaaa ataaatatag taaagataag
      721 gagttgcagc agtaccagta ctacagtgca ggcctgctct ccacatgcga ccctttctat
      781 gagcaacagc gccacttgct tggacccaaa aaaaagaaat tcaaggaaga caagaagctt
      841 aaagccaagt tgaaaaaagt gaagaaaaaa agacggcgcg atgaggagtt ttcctctgaa
      901 gaatctccac ggcaccacca tcaccagacc aaagtctttg ctaagttttc tcatgatgca
      961 cctccccctg gaaccaagaa gaaacactta tccattgaac agctcaatgc tcgccgcagg
     1021 aaagtgtggc tgagcattgt gaaaaaggaa ctaccaaagg ctaacaagca gaagtcttca
     1081 gctcgaaact tatttcttac aaatagccga aagcttgccc atcagtgcat gaaggaggtg
     1141 cgccgcgctg ctttgcaagc acagaaaaat tgtaaggaga ccctgcctcg tgcccggcgc
     1201 ttaaccaagg agatgcttct gtactggaag aagtatgaga aggtggagaa ggagcaccgc
     1261 aaacgagcgg agaaggaagc tttggagcag cggaagttgg atgaggaaat gcgggaggcc
     1321 aagaggcaac agcgaaaact caacttctta atcactcaga cagagttgta tgctcatttc
     1381 atgagtcgga aacgtgatat gggccatgat ggaatccagg aagaaatttt aaggaaacta
     1441 gaagatagtt ctacccagag acaaatcgac attggtggag gagtggtggt taacatcacc
     1501 caggaagact atgatagtaa ccattttaaa gcccaggccc tgaagaatgc tgaaaatgct
     1561 taccatattc accaagctcg aacaaggtca tttgatgaag atgcaaagga aagtcgggca
     1621 gctgctctta gggcagcaga caagtctggc tctgggtttg gagagagtta tagcttagcg
     1681 aatccatcta tccgggccgg tgaggatatt ccacaaccca ctattttcaa tggcaagttg
     1741 aaaggttacc agctgaaagg catgaactgg ttagcaaatc tatatgaaca gggtattaat
     1801 ggaattcttg ctgatgaaat gggtcttggt aaaactgtac agagcattgc cctcctggcc
     1861 catctggctg agagagaaaa catttgggga cctttcttaa taatctcacc tgcttctaca
     1921 cttaataatt ggcaccagga gtttacaaga tttgttccta aatttaaggt gctaccatat
     1981 tggggaaatc ctcatgatag aaaagttatc cggagattct ggagtcagaa gaccttatat
     2041 actcaggatg ctcccttcca tgtggtcatc actagctacc agctggtggt ccaggatgtc
     2101 aagtatttcc agcgggtcaa gtggcagtac atggtactgg atgaagctca ggcactgaag
     2161 agtagctcca gtgttcgttg gaagattctc ttacaattcc agtgtcggaa tcggcttttg
     2221 ttgactggaa cccccattca gaataccatg gcagagctct gggctctgct acatttcatt
     2281 atgccaacac tatttgattc ccatgaagaa tttaatgaat ggttttccaa agacattgaa
     2341 agtcatgctg aaaacaaatc tgctattgat gagaatcaac tctctcgatt gcacatgatc
     2401 ttgaagccat ttatgctgag aagaatcaaa aaagatgtag aaaatgaatt gtctgacaag
     2461 attgagattc taatgtactg ccaattgacc agccgacaaa agctcttata tcaggcacta
     2521 aagaataaaa tttccattga ggacttattg cagtcttcga tgggctctac acaacaagca
     2581 cagaacacca ccagcagcct catgaattta gtcatgcaat tcaggaaggt gtgtaatcac
     2641 ccagagttat tcgaacggca agaaacgtgg tctccatttc atatttccct aaagccatat
     2701 gaaatttcaa agtttatcta tcgtcatgga cagatcaggg tcttcaacca ttcacgagat
     2761 aggtggttga aggttcttct ttctccattt gcaccagact atatccagca gtctctcttc
     2821 catagaaaag gtattaatga aggaagctgt ttttctttcc ttcgatttat tgatgtctcg
     2881 ccagcagaaa tggcaaacct catgcttcag ggacttttgg ccaggtggtt agctcttttc
     2941 ctatctctga aagcctccta caggctccat cagctgcgct cttggggaga gccagatggg
     3001 gagagtcatc agagatatct gagaaataag gattttcttc ttggagttga ttttccactt
     3061 tccttcccca atctttgcag ctgccctttg ttaaagtctc ttgttttcag cagccactgt
     3121 aaagcagtga gtggctactc agaccaggtt gtccatcaat ggagatcagc tacctcctca
     3181 cttcgttgct gcctcctcac tgagctgcca tcctttttgt gtgtggccag tccacgagtc
     3241 accgcagtgc cgttggattc ttactgtaat gacagaagtg cagagtatga gagaggagtt
     3301 ctgaaggaag gagggagtct ggctgccaag cagtgtttgt tgaatggggc tcctgagctg
     3361 gctacggatt ggctgaatcg cagatcccag ttcttcccag agccagctgg agggctgttg
     3421 agcattaggc cccagaacgg ctggtctttc atcagaatcc caggcaagga gagcctcatc
     3481 actgacagtg gaaagctgta tgcccttgat atcctgttga ctcggctcaa gtctcaagga
     3541 catagggtcc ttatctactc tcagatgacc agaatgatag acctgctgga ggaatatatg
     3601 gtatacagga aacataccta catgaggctg gatggctcat ctaagatctc agagagacgg
     3661 gacatggttg ctgactttca gaccaggaac gacatctttg tgtttctgtt aagcacgagg
     3721 gctggaggac tgggcatcaa tctcacagct gctgacacag tgattttcta cgatagtgac
     3781 tggaacccca ctgtagacca gcaggccatg gatagagccc accgcttggg gcagacaaag
     3841 caggtcactg tgtaccggct tatctgtaaa ggcacaattg aggagcgtat tctgcagaga
     3901 gccaaggaaa agagtgagat tcagcgcatg gtgatttctg gtgggaactt caaaccagat
     3961 accttgaaac ccaaagaggt ggttagcctc cttctagatg atgaagaact ggagaagaaa
     4021 ctgagactgc ggcaggaaga gaaacggcag caggaggaaa gtaaccgagt gaaagaacgc
     4081 aaacgcaagc gggagaagta cgcagaaaag aaaaaaaagg aagatgagtt ggatgggaag
     4141 aggagaaaag agggtgtgaa ccttgtgatc ccgtttgttc ctgctgctga caattccaac
     4201 ctctctgctg atggagacga ttccttcata agtgtagact cagccatgcc cagcccattc
     4261 agtgagatct caatcagcag cgaacttcac actggctcca ttccccctga tgagagcagc
     4321 agtgacatgt tagtcatcgt ggatgaccca gcctcctcag cgcctcagtc tagagccacc
     4381 aactctcctg cttccataac aggctctgtg tcagacactg tgaatggaat ttccattcag
     4441 gaagtgccag ctgcaggacg tggtcactca gctcgaagcc gaggccgccc caagggttca
     4501 ggaagcacag ccaaaggagc ggggaaaggc cgaagccgca agtccactgc aggcagcgct
     4561 gctgcgatgg caggagccaa agcaggggct gcagcggctt ctgcagctgc ttatgccgcc
     4621 tacgggtaca atgtgtctaa aggaatctct gcaagcagtc ctcttcagac atccattgtc
     4681 cgacctgctg gccttgcaga ctttggacct tcaagcgcct cttctccctt aagttcccct
     4741 ctgaacaaag gaaataatat tcctgggact cctaaaagcc tccacatgac cagcagccta
     4801 gcctcagacc ccttgatccg gaaacagggc aaaggcacca atccctctgg aggacggtaa
     4861 ccatggtaat tatctctgcc ctctagcttc cttcaaccaa accagggact gcagtcctgg
     4921 gccataggtg gtctttggat ggcttgccca gtgtggcatc ttgcatccta tttggagagt
     4981 ggaaaggacc agttgtagca ggagaggaca ggcaggtgtt tggtgtgagc acttttatca
     5041 cctgtttcca aaggaatatc ctgggttcgg ccccacagca tcctagatgt actctgcagc
     5101 cgtactctta acctctttct ggggaagggc ctgacacaac cccttttata gatgctcagg
     5161 cacactgtct ccatccccat cccttcagct ctgactatgt ccctcatgaa ggctccatgg
     5221 gtgctgtgaa gagccttccc cagtggagac ttctctaaag gttatggttt ccttcagggc
     5281 taggaaagga ggaattgatt ccctggtaca catagtctgg gagcacgcct gggtctctca
     5341 gccctatttg ccacagtgtc atcactgtgt catcactgaa gaacacaagg aatgccagag
     5401 aagatggtag ctgtgagtga gggtgacaga ggctggagca agcagaggca caggcatttc
     5461 ccagcatttc ctccactgtc cagcacggtt cacaccaggg gagctttagg tcccaccagc
     5521 aacagtagca gcagctccca ctcaagggac ttcccagaag ccagtaaaga gaccaggaac
     5581 cacctcaatc agcaggacat cctcaccacc ctcttacaga tgcccctttg cccatcctga
     5641 atgcacagcc tccctggctt tgcccttcag cccctgcttg gctgtatgca ctgtctgtat
     5701 tgcactgaga aagaagggac agcaggagtg aaatggggag ggagctggct tggcaccacc
     5761 cctccctgcc ctgcccactc gcctaagctt gctgccctct gagaggggag aggggcggct
     5821 gggagggctt tccacctgac gtccctggtg gaacaggtgc ttctgggcgg gccagcctct
     5881 aatttgcaca cctgaaatcg cggaattgag tttagataga ttgatttttt aaacactttt
     5941 tttttggggg gggggagtag gtgtagggga atcatttaat ttaaatcata aaaattcccc
     6001 tacccaaacc ctgactcctg tgtacagatg ctctttagag ggaatcagaa aatgccaagc
     6061 cttttttctc tttgaatgtg ctgtctattt ttataactga acttgtacat atgtataaag
     6121 agagacacat ctttctttta ctaactggat aaaaaatctt aaataaaatg gagtgagata
     6181 attttatgta aattaaa
//
