LOCUS       NM_001109022            1062 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus indolethylamine N-methyltransferase (Inmt), mRNA.
ACCESSION   NM_001109022 XM_001061063 XM_347233
VERSION     NM_001109022.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Glynos NG, Carter L, Lee SJ, Kim Y, Kennedy RT, Mashour GA, Wang MM
            and Borjigin J.
  TITLE     Indolethylamine N-methyltransferase (INMT) is not essential for
            endogenous tryptamine-dependent methylation activity in rats
  JOURNAL   Sci Rep 13 (1), 280 (2023)
   PUBMED   36609666
  REMARK    GeneRIF: Indolethylamine N-methyltransferase (INMT) is not
            essential for endogenous tryptamine-dependent methylation activity
            in rats.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  AUTHORS   Thompson MA, Moon E, Kim UJ, Xu J, Siciliano MJ and Weinshilboum
            RM.
  TITLE     Human indolethylamine N-methyltransferase: cDNA cloning and
            expression, gene cloning, and chromosomal localization
  JOURNAL   Genomics 61 (3), 285-297 (1999)
   PUBMED   10552930
REFERENCE   3  (bases 1 to 1062)
  AUTHORS   Mozier NM, McConnell KP and Hoffman JL.
  TITLE     S-adenosyl-L-methionine:thioether S-methyltransferase, a new enzyme
            in sulfur and selenium metabolism
  JOURNAL   J Biol Chem 263 (10), 4527-4531 (1988)
   PUBMED   3350800
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474011.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001061063.1, XM_347233.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ214615.1, DV720539.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494, SAMN16676788
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     gene            1..1062
                     /gene="Inmt"
                     /note="indolethylamine N-methyltransferase"
                     /db_xref="GeneID:368066"
                     /db_xref="RGD:1597087"
     exon            1..212
                     /gene="Inmt"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..850
                     /gene="Inmt"
                     /EC_number="2.1.1.49"
                     /codon_start=1
                     /product="indolethylamine N-methyltransferase"
                     /protein_id="NP_001102492.1"
                     /db_xref="GeneID:368066"
                     /db_xref="RGD:1597087"
                     /translation="MAGKVYMGGEDYEKEFTPKDYLTTFYSFDSGTVAEQEIVKFSLQ
                     NLYQTFSTGGVGGDVLIDIGSGPTIYQLLSACEVFREIIATDYTPQNLQELQKWLKKE
                     PGAYDWSSIVQHVCELEGDRSRWQEKEAKLRRTVTRVLRCDVTKTPPLGSAQVPLADC
                     VLTFLAMECACPDVDTYRAALRRLAGLLKPGGHLVTLVTLRFQHYMVGPKKFSGVYLE
                     KETVEKAIQDAGFQVLRCNCVSLSYSEAYCVNDGLYFVVARKGPSA"
     exon            213..420
                     /gene="Inmt"
                     /inference="alignment:Splign:2.1.0"
     exon            421..1062
                     /gene="Inmt"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagtgagcat tctgcaggga caaaggaata caggcagctg tggaggctga ctagaatggc
       61 aggcaaggta tacatgggag gtgaggacta tgaaaaagag ttcactccca aagactacct
      121 gaccaccttc tacagcttcg actctggcac ggtggcagaa caggaaattg taaaattcag
      181 cctgcagaac ctctaccaga ccttctctac aggaggtgta gggggagatg tcttgattga
      241 cattggctct ggccccacca tctaccagct gctttcagca tgcgaggtct tccgggagat
      301 catcgccact gactacaccc cacagaacct gcaggagctg cagaaatggc tgaagaagga
      361 gccaggagcc tatgactggt cctccattgt acaacatgtg tgtgagctgg agggagacag
      421 aagcagatgg caggagaagg aggccaagct ccgaaggaca gtcactcgtg tactgaggtg
      481 tgatgtgacc aagacacccc cactggggtc agctcaagtg cctctggccg actgcgtgct
      541 gacctttctg gccatggagt gtgcctgtcc tgatgtagat acctaccggg cagccttgcg
      601 cagactggct ggcctgctga agccaggagg gcatctggtt accttggtta ctctgcgctt
      661 ccagcactat atggtgggcc ccaagaagtt ctctggggtc tacctggaga aggagacggt
      721 agaaaaggct attcaagatg ctggtttcca ggtgctaagg tgcaactgtg tctccctcag
      781 ctactcagag gcctactgtg tcaacgatgg tttatacttc gtggttgccc gaaagggtcc
      841 cagtgcctga ggccaccggc agagaattgc cttccctgag gaagttatag caatcatttg
      901 taaagccttg ctccatagcc tcctaacact gaccatgttg cttctctcta taacctggtc
      961 accagttcac aagggaaaac tcaaggttca gcaccaaaat ccatccccct tactcctttt
     1021 gtaccctgat caaagctcat taaaataaag tggtttctct gg
//
