LOCUS       NM_001038591            1240 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus inhibitor of growth family, member 1 (Ing1),
            mRNA.
ACCESSION   NM_001038591 XM_225039
VERSION     NM_001038591.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1240)
  AUTHORS   Shi X, Hong T, Walter KL, Ewalt M, Michishita E, Hung T, Carney D,
            Pena P, Lan F, Kaadige MR, Lacoste N, Cayrou C, Davrazou F, Saha A,
            Cairns BR, Ayer DE, Kutateladze TG, Shi Y, Cote J, Chua KF and
            Gozani O.
  TITLE     ING2 PHD domain links histone H3 lysine 4 methylation to active
            gene repression
  JOURNAL   Nature 442 (7098), 96-99 (2006)
   PUBMED   16728974
REFERENCE   2  (bases 1 to 1240)
  AUTHORS   Watanabe-Fukunaga R, Iida S, Shimizu Y, Nagata S and Fukunaga R.
  TITLE     SEI family of nuclear factors regulates p53-dependent
            transcriptional activation
  JOURNAL   Genes Cells 10 (8), 851-860 (2005)
   PUBMED   16098148
REFERENCE   3  (bases 1 to 1240)
  AUTHORS   Ha S, Park S, Yun CH and Choi Y.
  TITLE     Characterization of nuclear localization signal in mouse ING1
            homolog protein
  JOURNAL   Biochem Biophys Res Commun 293 (1), 163-166 (2002)
   PUBMED   12054579
REFERENCE   4  (bases 1 to 1240)
  AUTHORS   Gunduz M, Ouchida M, Fukushima K, Hanafusa H, Etani T, Nishioka S,
            Nishizaki K and Shimizu K.
  TITLE     Genomic structure of the human ING1 gene and tumor-specific
            mutations detected in head and neck squamous cell carcinomas
  JOURNAL   Cancer Res 60 (12), 3143-3146 (2000)
   PUBMED   10866301
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY624102.1.
            
            [WARNING] On Oct 11, 2024 this sequence was replaced by
            NM_001038591.2.
            
            On Jan 6, 2006 this sequence version replaced XM_225039.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY624102.1, AY624101.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132305, SAMN06680435
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1240
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.5"
     gene            1..1240
                     /gene="Ing1"
                     /gene_synonym="p33ING1b; p33ING1c"
                     /note="inhibitor of growth family, member 1"
                     /db_xref="GeneID:306626"
                     /db_xref="RGD:1306330"
     exon            1..176
                     /gene="Ing1"
                     /gene_synonym="p33ING1b; p33ING1c"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..880
                     /gene="Ing1"
                     /gene_synonym="p33ING1b; p33ING1c"
                     /codon_start=1
                     /product="inhibitor of growth protein 1"
                     /protein_id="NP_001033680.1"
                     /db_xref="GeneID:306626"
                     /db_xref="RGD:1306330"
                     /translation="MLSPANGEQIHLVNYVEDYLDSIESLPFDLQRNVSLMREIDAKY
                     QEILKELDDYYEKFKRETDSTQKRRVLHCIQRALIRSQELGDEKIQIVSQMVELVENR
                     SRQVDSHVELFEAHQDISDGTGGGGKAGQDKSKSEAITQADKPNNKRSRRQRNNENRE
                     NASNNHDHDDITSGTPKEKKAKISKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQV
                     SYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGESEKTMDKALEKSKKERA
                     YNR"
     exon            177..1240
                     /gene="Ing1"
                     /gene_synonym="p33ING1b; p33ING1c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggaaagccg ccgagtcgcc ggggacctcc ggggtgaacc atgttgagtc ctgccaacgg
       61 ggagcagatc cacctggtga actatgtgga ggattacctg gactcaatcg agtcactgcc
      121 tttcgacctg cagaggaacg tctcgctgat gcgggagatc gacgccaaat accaagagat
      181 cctgaaggag ttggatgact actatgagaa gttcaagcgg gagacggaca gcacccagaa
      241 gaggcgggtg ctgcactgca tccagagggc cctgatccga agccaggagc tgggcgacga
      301 gaagatccag atcgtgagtc agatggtgga gctggtggag aaccgcagca ggcaggtgga
      361 cagtcatgta gagctcttcg aagcacacca ggacatcagt gatggcactg gtggtggcgg
      421 caaggcaggc caggacaagt caaagagtga agcgatcaca caggcagata agccaaataa
      481 caagcggtcc cggaggcagc gaaacaacga gaaccgagaa aacgcctcga acaatcacga
      541 ccatgacgac atcacctcag gaacgcccaa ggagaagaaa gcaaaaatct caaagaagaa
      601 gaaacgctct aaggccaaag cagagaggga ggcgtccccc gcggacctcc ccatcgaccc
      661 caacgagccc acgtactgtc tgtgcaacca ggtctcctat ggagagatga tcggctgtga
      721 caacgacgag tgtcccatcg agtggttcca cttttcttgt gtgggactca accataaacc
      781 aaagggcaag tggtactgcc ccaagtgccg tggggagagt gaaaagacaa tggacaaggc
      841 cctggagaag tccaagaaag agagggctta caacaggtag ttagcgcaca tttgcccacg
      901 atccagagta acaaaaccca ccagtgtatt tatgatgtcg ctgccttttc ggaagtatga
      961 ggacggtcag acaagtgttt ttatagagtg ttagcaatgg atcctctcct tgggatggcg
     1021 gagacagccc gtgtcttcat ggtatacctt gtttccacac agggtctgcc ggtcagcaat
     1081 ttagaaacca caaatacagg tccgaattaa acgtgtccac aagtgtcaga ctgatttttg
     1141 gggttgggga gtgacttgga agtaacctaa catatataaa gaagagattt aatttggctg
     1201 ttttaacaaa aatgttacgg tttacaaaaa aaaaaaaaaa
//
