LOCUS       NM_001106335            3154 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus inner centromere protein (Incenp), mRNA.
ACCESSION   NM_001106335 XM_001074188 XM_215184
VERSION     NM_001106335.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3154)
  AUTHORS   Parra,M.T., Gomez,R., Viera,A., Llano,E., Pendas,A.M., Rufas,J.S.
            and Suja,J.A.
  TITLE     Sequential assembly of centromeric proteins in male mouse meiosis
  JOURNAL   PLoS Genet 5 (3), e1000417 (2009)
   PUBMED   19283064
REFERENCE   2  (bases 1 to 3154)
  AUTHORS   Qi,W., Tang,Z. and Yu,H.
  TITLE     Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is
            required for the kinetochore localization of Plk1
  JOURNAL   Mol Biol Cell 17 (8), 3705-3716 (2006)
   PUBMED   16760428
REFERENCE   3  (bases 1 to 3154)
  AUTHORS   Vader,G., Kauw,J.J., Medema,R.H. and Lens,S.M.
  TITLE     Survivin mediates targeting of the chromosomal passenger complex to
            the centromere and midbody
  JOURNAL   EMBO Rep 7 (1), 85-92 (2006)
   PUBMED   16239925
REFERENCE   4  (bases 1 to 3154)
  AUTHORS   Parra,M.T., Viera,A., Gomez,R., Page,J., Carmena,M., Earnshaw,W.C.,
            Rufas,J.S. and Suja,J.A.
  TITLE     Dynamic relocalization of the chromosomal passenger complex
            proteins inner centromere protein (INCENP) and aurora-B kinase
            during male mouse meiosis
  JOURNAL   J Cell Sci 116 (Pt 6), 961-974 (2003)
   PUBMED   12584241
REFERENCE   5  (bases 1 to 3154)
  AUTHORS   Uren,A.G., Wong,L., Pakusch,M., Fowler,K.J., Burrows,F.J.,
            Vaux,D.L. and Choo,K.H.
  TITLE     Survivin and the inner centromere protein INCENP show similar
            cell-cycle localization and gene knockout phenotype
  JOURNAL   Curr Biol 10 (21), 1319-1328 (2000)
   PUBMED   11084331
REFERENCE   6  (bases 1 to 3154)
  AUTHORS   Ainsztein,A.M., Kandels-Lewis,S.E., Mackay,A.M. and Earnshaw,W.C.
  TITLE     INCENP centromere and spindle targeting: identification of
            essential conserved motifs and involvement of heterochromatin
            protein HP1
  JOURNAL   J Cell Biol 143 (7), 1763-1774 (1998)
   PUBMED   9864353
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_215184.4, XM_001074188.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3154
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..3154
                     /gene="Incenp"
                     /note="inner centromere protein"
                     /db_xref="GeneID:293733"
                     /db_xref="RGD:1305292"
     exon            1..131
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            132..282
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     CDS             143..2830
                     /gene="Incenp"
                     /note="inner centromere protein antigens 135/155kDa"
                     /codon_start=1
                     /product="inner centromere protein"
                     /protein_id="NP_001099805.1"
                     /db_xref="GeneID:293733"
                     /db_xref="RGD:1305292"
                     /translation="MGTTAPGPANLLDLCDQKLLDFVYNVDNKDFMWLKEIEEEAERM
                     FVREFNNEPELMPKTPSQKNRRKKRRVSNIQDENRDPVRKRLSRRKSRSSQVGPRHRR
                     SKLGAVVEENGSPVLRRITRAAAAAAAAAASTSASVASASSSPTTVSPIVLIKKAVVE
                     VSTGEQLSAELQLIKLKGGLPQSSVPAPATSSVSQGTLTSEEEATPKKSEAGRLDSAT
                     DSVAVNSLKATPQSPKNRGVGEARSVSKLKIARASRGLQDSPGSTDSPWQERVLSPIL
                     PNNILSTTAKNPLGSIQSVQQSLISQDSQVPLAKKYCLVTQQENASRRSSRIAKKAGK
                     EPEASARIICHSYLERLLNVEVPQNVGLEKEPVEVAEPEEAVEEQEVSKNSGCSSKPH
                     SATKMAISTPTSKPVATGQATAVEEQDAELDQTDGHREPPQSVRRKRSYKQAMSELDE
                     EHLEDEELQPPRNKTPSPPCPASKVVRPLRTFLHTVQKNQMLMTPTLASRSSVMKSFI
                     KRNTPLRVDPKEKERQRLESLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVL
                     QARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEKAKKKAAAKKMEEMEARRKQ
                     EEEARRLKWLQQEEEERRHQEMLQRKKEEEQERRKAAEARRLAEQREQERRREQERRE
                     QERREQERREQERREQERREQERREQERREQERLRAKREMQEREKALRLQKERLQREL
                     EEKKKKEEQQRLAEQQLQEEQAKKAKEVAAGKALNMTVDVQSPVCTSYQMTPQGPKSF
                     PKISMDDYGMDLNSDDSTDDEAHPRKPIPSWAKGTQLSQAIVHQYYHPPNILELFGSI
                     LPLDLEDIFKKRKTRYHKRTSSAVWNSPPLKATIPSSGD"
     exon            283..396
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            397..1172
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1224
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..1282
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            1283..1397
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            1398..1449
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1564
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            1565..1699
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            1700..1809
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            1810..1930
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            1931..2050
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            2051..2301
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            2302..2380
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            2381..2485
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            2486..2636
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
     exon            2637..3154
                     /gene="Incenp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttcccggttg gttctcgcct gcggcgagct cgctgtaccg ggagtcctgc gggcttggct
       61 tggcgggaag ctttatctga ggaagccgcg gactggaatc ggagtggtcc gggcagacgt
      121 ggcgccgccg gacagtgcca ccatggggac cacagcccca gggcctgcta accttctgga
      181 cctatgtgac cagaaactcc tggactttgt ctacaatgtg gacaacaagg acttcatgtg
      241 gcttaaggag attgaggagg aggccgagcg aatgtttgtc agagaattca acaatgagcc
      301 agagctgatg cccaaaactc cttctcagaa aaaccgtcgg aagaagaggc gggtgtctaa
      361 cattcaggat gaaaacagag atcctgtgag gaaaaggttg tcccgcagaa agtctcggag
      421 cagtcaggta ggcccccggc accgccgcag caagctgggt gctgttgttg aggagaatgg
      481 ttcgcctgtg ttgcgtcgga taacccgggc agcagctgca gcagcagcag cggcagcatc
      541 aacgtcagcg tctgtggcat cagcttcttc ttctcccact acggtgtctc ccatagtgct
      601 aatcaaaaaa gctgtggtag aggtaagcac cggtgagcaa ctgagtgcag agcttcaact
      661 cattaagctc aaaggtggcc ttcctcagtc ttcagtccca gctccagcca catcttcagt
      721 ttcccaaggc accctgacct cagaagagga agcaacaccc aagaaatcag aggctgggag
      781 gctggactct gccacagact ccgttgcagt gaactccctc aaggctaccc ctcagagccc
      841 caagaaccga ggggttgggg aagcacgttc tgtttccaag ctcaagattg ctcgggcctc
      901 caggggcctg caggactctc ctggctctac ggactctcca tggcaagagc gggtgctttc
      961 tcctattctg ccgaataaca tcttgtccac cacagccaag aaccctcttg ggagtattca
     1021 gtcagtgcag caaagcctga tttcccagga ttcccaagtg ccattagcca aaaagtattg
     1081 tttggtgact caacaagaaa atgccagtcg cagatcaagc aggattgcta agaaggctgg
     1141 caaagagcca gaggcctctg ctcgcatcat ttgtcacagt tacctggaga ggctcctgaa
     1201 tgttgaagtg cctcagaatg ttggcctgga aaaggagcct gttgaggtgg ccgagcctga
     1261 ggaggcagta gaggagcaag aggtctccaa gaacagtgga tgttcctcca aaccccacag
     1321 tgccaccaag atggcgatca gtacgcctac ctcgaagcct gtggccactg gccaggcaac
     1381 agctgttgaa gagcaagacg ctgagcttga ccaaacagat ggacacagag aaccacccca
     1441 gagtgtcagg aggaaacgca gttacaagca ggccatgagt gaactggatg aggagcatct
     1501 ggaggatgaa gagctgcagc ctccccggaa caagacccct tccccaccct gtccagccag
     1561 caaggtggta cggcccctcc ggactttctt gcacacagtg cagaagaacc agatgctcat
     1621 gacccctact ctggcctccc gcagcagtgt catgaagtcc tttattaaac gcaacactcc
     1681 actccgtgtg gaccctaagg agaaggagcg ccagcgccta gagagcctgc ggcggaagga
     1741 ggaggccgag cagctgcgca gacagaaggt agaggaagac aagcggcggc gcctggagga
     1801 ggtgaagctg aagcgtgaag agcgcctccg caaggtattg caggctcgtg agcgggtgga
     1861 acagatgaag gaggaaaaga agaagcagat tgagcagaag tttgctcaga ttgatgagaa
     1921 gacagagaag gctaaggagg agcggctggc agagaaggcc aagaagaagg cggccgccaa
     1981 gaagatggaa gagatggagg cgcgcaggaa gcaggaggag gaggcgcgca ggctcaagtg
     2041 gctccagcag gaggaagagg agcggcggca tcaagaaatg ctacagcgga agaaggagga
     2101 agaacaggag cgccgcaaag cagctgaggc caggcgactg gcagaacagc gtgagcaaga
     2161 gcggcggaga gagcaagaac ggagagagca ggaacggaga gagcaggagc ggagagagca
     2221 ggagcggaga gagcaggagc ggagggagca ggagcggaga gagcaggaac ggagggagca
     2281 ggaacgactt cgggccaaga gggagatgca ggagagagag aaggccctgc ggctccaaaa
     2341 ggaacgactt cagagggaac tggaagagaa gaagaagaag gaagagcagc agcgcctggc
     2401 tgagcagcaa ctgcaggagg agcaggcaaa gaaagctaag gaggtggccg ccggcaaagc
     2461 actgaacatg actgtggatg tgcagtctcc tgtttgtacc tcatatcaga tgactccaca
     2521 aggacccaag tcctttccca agatcagcat ggatgactat gggatggacc tgaatagcga
     2581 tgactccaca gatgatgagg cccatccccg gaaacccatc ccttcctggg ccaaaggcac
     2641 tcagctcagc caggccatcg tccaccagta ctaccacccc ccaaacattc tagagctctt
     2701 cggatctatt ctcccactgg acttggagga catctttaag aagaggaaga ctcgctacca
     2761 caagcgcacc agctctgctg tttggaactc accacctctg aaagccacca tccccagcag
     2821 tggggactaa cctatagcct gaagaagcca tgaggcaagc cctcaatcct tttggcagta
     2881 cagggcccat gtgtgtcttt ctgtttgtct ttctgtctgt ttctgtgttg gactggtgtc
     2941 cttctgtctg acttgccatt gttcaagtgg atatcaatgt tctctgtcag gtattcccag
     3001 acctctttgg aggatgggct ttatgcctgg ggaagaacca ggttcagcac tgatcaatct
     3061 ggaggcagta ctctgtaaat agattgttac agttcagttg aatgaatttt agtttctagt
     3121 gtttgtgagg tagtttaata aagtatatag cctg
//
