LOCUS       NM_001398704             790 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus inner mitochondrial membrane peptidase subunit 2
            (Immp2l), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001398704 XM_002729645
VERSION     NM_001398704.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 790)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 790)
  AUTHORS   Mossmann,D., Meisinger,C. and Vogtle,F.N.
  TITLE     Processing of mitochondrial presequences
  JOURNAL   Biochim Biophys Acta 1819 (9-10), 1098-1106 (2012)
   PUBMED   22172993
  REMARK    Review article
REFERENCE   3  (bases 1 to 790)
  AUTHORS   Ma,Y., Mehta,S.L., Lu,B. and Li,P.A.
  TITLE     Deficiency in the inner mitochondrial membrane peptidase 2-like
            (Immp21) gene increases ischemic brain damage and impairs
            mitochondrial function
  JOURNAL   Neurobiol Dis 44 (3), 270-276 (2011)
   PUBMED   21824519
REFERENCE   4  (bases 1 to 790)
  AUTHORS   Lu,B., Poirier,C., Gaspar,T., Gratzke,C., Harrison,W., Busija,D.,
            Matzuk,M.M., Andersson,K.E., Overbeek,P.A. and Bishop,C.E.
  TITLE     A mutation in the inner mitochondrial membrane peptidase 2-like
            gene (Immp2l) affects mitochondrial function and impairs fertility
            in mice
  JOURNAL   Biol Reprod 78 (4), 601-610 (2008)
   PUBMED   18094351
REFERENCE   5  (bases 1 to 790)
  AUTHORS   Burri,L., Strahm,Y., Hawkins,C.J., Gentle,I.E., Puryer,M.A.,
            Verhagen,A., Callus,B., Vaux,D. and Lithgow,T.
  TITLE     Mature DIABLO/Smac is produced by the IMP protease complex on the
            mitochondrial inner membrane
  JOURNAL   Mol Biol Cell 16 (6), 2926-2933 (2005)
   PUBMED   15814844
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Dec 21, 2021 this sequence version replaced XM_002729645.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM092161.1, SRR26643288.26547.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                JAXUCZ010000006.1  63797229-63797257
            30-102              JAXUCZ010000006.1  63797663-63797735
            103-239             JAXUCZ010000006.1  63845705-63845841
            240-343             JAXUCZ010000006.1  63897802-63897905
            344-409             JAXUCZ010000006.1  64388906-64388971
            410-512             JAXUCZ010000006.1  64478223-64478325
            513-790             JAXUCZ010000006.1  64696629-64696906
FEATURES             Location/Qualifiers
     source          1..790
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q21"
     gene            1..790
                     /gene="Immp2l"
                     /note="inner mitochondrial membrane peptidase subunit 2"
                     /db_xref="GeneID:100359529"
                     /db_xref="RGD:2323665"
     exon            1..29
                     /gene="Immp2l"
                     /inference="alignment:Splign:2.1.0"
     exon            30..102
                     /gene="Immp2l"
                     /inference="alignment:Splign:2.1.0"
     exon            103..239
                     /gene="Immp2l"
                     /inference="alignment:Splign:2.1.0"
     CDS             105..632
                     /gene="Immp2l"
                     /note="IMP2 inner mitochondrial membrane peptidase-like;
                     rCG61688-like"
                     /codon_start=1
                     /product="mitochondrial inner membrane protease subunit 2"
                     /protein_id="NP_001385633.1"
                     /db_xref="GeneID:100359529"
                     /db_xref="RGD:2323665"
                     /translation="MAQSQGWVRRCFKAFCKGFFVAVPVAVTFLDRVVCVARVEGSSM
                     QPSLNPGGSQSSDVVLLNHWKVRNFEVQRGDIVSLVSPKNPEQKIIKRVIALEGDIIR
                     PIGYKNQLVKVPRGHMWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPERWQKLE
                     SVLPPERSPVHTSEE"
     exon            240..343
                     /gene="Immp2l"
                     /inference="alignment:Splign:2.1.0"
     exon            344..409
                     /gene="Immp2l"
                     /inference="alignment:Splign:2.1.0"
     exon            410..512
                     /gene="Immp2l"
                     /inference="alignment:Splign:2.1.0"
     exon            513..790
                     /gene="Immp2l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacttcccct gggttgaact tcgccgcggg attttggcca aattgggcga gggtacaata
       61 ttaccactta ccccttctca ccgaggaaga gcgggagaaa gggtatggca cagtcacaag
      121 gctgggtgcg aagatgcttc aaggcctttt gcaaaggctt ctttgtggcg gtgcctgtgg
      181 cagtcacttt cttggatcgg gtggtctgtg tggctcgagt ggagggatcg tcgatgcagc
      241 cttctttgaa tcctggggga agccagtcct cagatgtggt acttctgaac cactggaaag
      301 tgaggaattt tgaagtacag cgtggtgaca ttgtgtcatt ggtgtctcct aaaaacccag
      361 agcagaaaat cattaagaga gtgatcgctc ttgaaggaga tattataaga cccattggat
      421 acaaaaacca gttggtcaaa gtcccccgtg gtcacatgtg ggttgaagga gatcatcatg
      481 gacacagttt tgatagtaat tcttttggac cggtttctct gggactcctg catgcccatg
      541 ctacacatat cttgtggcct ccagagcgct ggcagaaact ggaatctgtt cttcctccgg
      601 agcgctcccc agtccatact agtgaggagt aactgcatga gagcccacca caggaggagt
      661 ggaacacacc agaagcctcc tcgagaaggg agaagttcca gtgatgcgga acaagaggcc
      721 tctgtgtgtc ttttaagatt gtctggaatt gtaaagcaag attttctata ttaaacagta
      781 ataaatgaca
//
