LOCUS       NM_001393800            1612 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus interleukin enhancer binding factor 2 (Ilf2),
            mRNA.
ACCESSION   NM_001393800 XM_006232624
VERSION     NM_001393800.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1612)
  AUTHORS   Barallobre-Barreiro,J., Oklu,R., Lynch,M., Fava,M., Baig,F.,
            Yin,X., Barwari,T., Potier,D.N., Albadawi,H., Jahangiri,M.,
            Porter,K.E., Watkins,M.T., Misra,S., Stoughton,J. and Mayr,M.
  TITLE     Extracellular matrix remodelling in response to venous
            hypertension: proteomics of human varicose veins
  JOURNAL   Cardiovasc Res 110 (3), 419-430 (2016)
   PUBMED   27068509
REFERENCE   2  (bases 1 to 1612)
  AUTHORS   Liu,X., Zhang,C., Qian,L., Zhang,C., Wu,K., Yang,C., Yan,D., Wu,X.
            and Shi,J.
  TITLE     NF45 inhibits cardiomyocyte apoptosis following myocardial
            ischemia-reperfusion injury
  JOURNAL   Pathol Res Pract 211 (12), 955-962 (2015)
   PUBMED   26573128
  REMARK    GeneRIF: Our findings establish an anti-apoptotic role of NF45 in
            response to myocardial ischemia-reperfusion injury
REFERENCE   3  (bases 1 to 1612)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 1612)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 1612)
  AUTHORS   Harashima,A., Guettouche,T. and Barber,G.N.
  TITLE     Phosphorylation of the NFAR proteins by the dsRNA-dependent protein
            kinase PKR constitutes a novel mechanism of translational
            regulation and cellular defense
  JOURNAL   Genes Dev 24 (23), 2640-2653 (2010)
   PUBMED   21123651
REFERENCE   6  (bases 1 to 1612)
  AUTHORS   Lopez-Fernandez,L.A., Parraga,M. and del Mazo,J.
  TITLE     Ilf2 is regulated during meiosis and associated to
            transcriptionally active chromatin
  JOURNAL   Mech Dev 111 (1-2), 153-157 (2002)
   PUBMED   11804788
REFERENCE   7  (bases 1 to 1612)
  AUTHORS   Andersen,J.S., Lyon,C.E., Fox,A.H., Leung,A.K., Lam,Y.W., Steen,H.,
            Mann,M. and Lamond,A.I.
  TITLE     Directed proteomic analysis of the human nucleolus
  JOURNAL   Curr Biol 12 (1), 1-11 (2002)
   PUBMED   11790298
REFERENCE   8  (bases 1 to 1612)
  AUTHORS   Reichman,T.W., Muniz,L.C. and Mathews,M.B.
  TITLE     The RNA binding protein nuclear factor 90 functions as both a
            positive and negative regulator of gene expression in mammalian
            cells
  JOURNAL   Mol Cell Biol 22 (1), 343-356 (2002)
   PUBMED   11739746
REFERENCE   9  (bases 1 to 1612)
  AUTHORS   Satoh,M., Shaheen,V.M., Kao,P.N., Okano,T., Shaw,M., Yoshida,H.,
            Richards,H.B. and Reeves,W.H.
  TITLE     Autoantibodies define a family of proteins with conserved
            double-stranded RNA-binding domains as well as DNA binding activity
  JOURNAL   J Biol Chem 274 (49), 34598-34604 (1999)
   PUBMED   10574923
REFERENCE   10 (bases 1 to 1612)
  AUTHORS   Kao,P.N., Chen,L., Brock,G., Ng,J., Kenny,J., Smith,A.J. and
            Corthesy,B.
  TITLE     Cloning and expression of cyclosporin A- and FK506-sensitive
            nuclear factor of activated T-cells: NF45 and NF90
  JOURNAL   J Biol Chem 269 (32), 20691-20699 (1994)
   PUBMED   7519613
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Mar 12, 2021 this sequence version replaced XM_006232624.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC167105.1, SRR26643288.10305.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-111               JAXUCZ010000002.1  178256927-178257037
            112-171             JAXUCZ010000002.1  178257816-178257875
            172-214             JAXUCZ010000002.1  178258214-178258256
            215-319             JAXUCZ010000002.1  178262117-178262221
            320-397             JAXUCZ010000002.1  178262535-178262612
            398-500             JAXUCZ010000002.1  178262933-178263035
            501-566             JAXUCZ010000002.1  178264087-178264152
            567-683             JAXUCZ010000002.1  178265341-178265457
            684-762             JAXUCZ010000002.1  178266319-178266397
            763-850             JAXUCZ010000002.1  178266872-178266959
            851-912             JAXUCZ010000002.1  178267695-178267756
            913-1027            JAXUCZ010000002.1  178267827-178267941
            1028-1118           JAXUCZ010000002.1  178268048-178268138
            1119-1612           JAXUCZ010000002.1  178268280-178268773
FEATURES             Location/Qualifiers
     source          1..1612
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1612
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /note="interleukin enhancer binding factor 2"
                     /db_xref="GeneID:310612"
                     /db_xref="RGD:1305734"
     exon            1..111
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..1279
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /note="liver regeneration-related protein LRRG031"
                     /codon_start=1
                     /product="interleukin enhancer-binding factor 2"
                     /protein_id="NP_001380729.1"
                     /db_xref="GeneID:310612"
                     /db_xref="RGD:1305734"
                     /translation="MRGDRGRGRGGRFGSRGGPGGGFRPFVPHIPFDFYLCEMAFPRV
                     KPAPDETSFSEALLKRNQDLAPNSAEQASILSLVTKINNVIDNLIVAPGTFEVQIEEV
                     RQVGSYKKGTMTTGHNVADLVVILKILPTLEAVAALGNKVVESLRAQDPSEVLTMLTN
                     ETGFEISSSDATVKILITTVPPNLRKLDPELHLDIKVLQSALAAIRHARWFEENASQS
                     TVKVLIRLLKDLRIRFPGFEPLTPWILDLLGHYAVMNNPTRQPLALNVAYRRCLQILA
                     AGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQTLVRILSHGGFRKILGQEG
                     DASYLASEISTWDGVIVTPSEKAYEKPPEKKEGEEEEENTEEPPQGEEEESMETQE"
     exon            112..171
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
     exon            172..214
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
     exon            215..319
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
     exon            320..397
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
     exon            398..500
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
     exon            501..566
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
     exon            567..683
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
     exon            684..762
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
     exon            763..850
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
     exon            851..912
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1027
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..1118
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1612
                     /gene="Ilf2"
                     /gene_synonym="Ab1-143"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcaggcgt ttgttgggac acgccgaccc gacgtttctc tgttaccttg attcttccaa
       61 gcgaagagcg gttgagtggt ctccattgtt caggattaag cgagccatga ggggtgacag
      121 aggacgtggt cgtggtgggc gctttggttc cagaggaggt cctggaggag ggttcaggcc
      181 ttttgtgccc cacatcccct ttgatttcta tttgtgtgaa atggcttttc cccgggtcaa
      241 accagcacct gatgagacct ccttcagtga agccttgttg aagaggaatc aagaccttgc
      301 ccccaattct gctgagcagg cttctatcct ttctttggtg acaaaaataa acaatgtgat
      361 tgacaacttg attgtggctc cagggacatt tgaagtgcaa attgaagaag tccgacaggt
      421 aggatcatat aaaaagggga caatgactac aggacacaat gtggctgacc tggtggtaat
      481 actaaagatt ctgccaacat tggaagctgt tgccgccctt gggaacaaag ttgtggaaag
      541 cctgagggca caggatccct cagaagtctt gaccatgctg actaatgaaa ctggctttga
      601 aattagctct tctgatgcta cggtgaaaat tctcattaca acagtgccac ccaatctccg
      661 gaaactggac ccagaactcc atttggacat caaggtgttg cagagtgcct tagcggccat
      721 ccggcatgcc cgctggtttg aagaaaatgc ttctcagtcc acagttaaag ttctcatcag
      781 attgctaaag gacttacgga ttcgttttcc tggttttgag cctcttacac cctggatcct
      841 tgacctactt gggcactacg ctgtaatgaa caaccccacc agacagcctt tggccctgaa
      901 cgtggcttac aggcgctgct tgcagattct ggctgcagga ctgttcctgc cagggtcagt
      961 gggcatcact gacccctgtg agagtggcaa cttcagggta cacacagtta tgaccctaga
     1021 acagcaggat atggtctgct acacagctca gactctggtt cgaattctct cccacggagg
     1081 ctttcggaag atccttgggc aggaggggga cgccagctat cttgcttctg aaatatctac
     1141 ctgggatgga gtgattgtga caccttcaga aaaggcctat gaaaagccgc ctgagaagaa
     1201 ggagggagag gaagaggaag agaacacaga agagccgcct cagggagaag aagaagaaag
     1261 catggagact caggagtgac cttccccaag ggaaaatgag cctgagccag ccaccacggg
     1321 gcttcagatg gtggcatttc tgtggtatag ggagatagca ggaaggaaaa cagactgtaa
     1381 agaaaatgtc attctagtgt tttgatagtg gccaagcagc tagaaatctc ccatttgtga
     1441 ctgcatatgc catccgtcca tctgtaatga agcagatgcc acacattccc aatatttaaa
     1501 cctaaccact cccaaccagt accttttgtt gaaatgttgt aaactgttgt tgagtgtctg
     1561 gggatttttt tttttttttc taagaaaaat gattaaagta cttcctacta gg
//
