LOCUS       NM_001107814            3025 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus interleukin 36 receptor antagonist (Il36rn),
            mRNA.
ACCESSION   NM_001107814 XM_001077078 XM_231101
VERSION     NM_001107814.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3025)
  AUTHORS   Luo,C., Xie,X., Feng,X., Lei,B., Fang,C., Li,Y., Cai,X., Ling,G.
            and Zheng,B.
  TITLE     Deficiency of Interleukin-36 Receptor Protected Cardiomyocytes from
            Ischemia-Reperfusion Injury in Cardiopulmonary Bypass
  JOURNAL   Med Sci Monit 26, e918933 (2020)
   PUBMED   32048631
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3025)
  AUTHORS   Gresnigt,M.S., Rosler,B., Jacobs,C.W., Becker,K.L., Joosten,L.A.,
            van der Meer,J.W., Netea,M.G., Dinarello,C.A. and van de
            Veerdonk,F.L.
  TITLE     The IL-36 receptor pathway regulates Aspergillus fumigatus-induced
            Th1 and Th17 responses
  JOURNAL   Eur J Immunol 43 (2), 416-426 (2013)
   PUBMED   23147407
REFERENCE   3  (bases 1 to 3025)
  AUTHORS   Vigne,S., Palmer,G., Lamacchia,C., Martin,P., Talabot-Ayer,D.,
            Rodriguez,E., Ronchi,F., Sallusto,F., Dinh,H., Sims,J.E. and
            Gabay,C.
  TITLE     IL-36R ligands are potent regulators of dendritic and T cells
  JOURNAL   Blood 118 (22), 5813-5823 (2011)
   PUBMED   21860022
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474001.2.
            
            [WARNING] On Oct 24, 2024 this sequence was replaced by
            NM_001107814.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_231101.3, XM_001077078.1.
FEATURES             Location/Qualifiers
     source          1..3025
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p13"
     gene            1..3025
                     /gene="Il36rn"
                     /gene_synonym="Il1f5"
                     /note="interleukin 36 receptor antagonist"
                     /db_xref="GeneID:311783"
                     /db_xref="RGD:1311212"
     exon            1..171
                     /gene="Il36rn"
                     /gene_synonym="Il1f5"
                     /inference="alignment:Splign:2.1.0"
     exon            172..299
                     /gene="Il36rn"
                     /gene_synonym="Il1f5"
                     /inference="alignment:Splign:2.1.0"
     exon            300..352
                     /gene="Il36rn"
                     /gene_synonym="Il1f5"
                     /inference="alignment:Splign:2.1.0"
     CDS             321..791
                     /gene="Il36rn"
                     /gene_synonym="Il1f5"
                     /note="interleukin-1 family member 5; interleukin 1
                     family, member 5 (delta)"
                     /codon_start=1
                     /product="interleukin-36 receptor antagonist protein"
                     /protein_id="NP_001101284.1"
                     /db_xref="GeneID:311783"
                     /db_xref="RGD:1311212"
                     /translation="MMVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEIS
                     VVPNRALDASLSPVILGVQGGSQCLSCGTEKEPILKLEPVNIMELYLGTKESKSFTFY
                     RRDLGLTSSFESAAYPGWFLCTSPEADQPVRLTQISEDPAWDAPITDFYFQQCD"
     exon            353..438
                     /gene="Il36rn"
                     /gene_synonym="Il1f5"
                     /inference="alignment:Splign:2.1.0"
     exon            439..566
                     /gene="Il36rn"
                     /gene_synonym="Il1f5"
                     /inference="alignment:Splign:2.1.0"
     exon            567..3025
                     /gene="Il36rn"
                     /gene_synonym="Il1f5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggactgaagg aagggaaaga gaaagagaga gaagaaagaa ggttgctctg actttctgga
       61 tctactttct gaagtagctg agtgtacctg gagaattgga aaggccagag aaagtccttc
      121 tgaatctttg gaagaaggct gactgttgaa gcttccttca ttgagagata ggaccacggc
      181 atcttggaga agcaagcagt catccacagg ctcctatctg gagaaagggg agatctgatg
      241 gatgctttgt ggggtctttc ctaacttcca gatccagaat ctcctccttc acacaggctg
      301 gtctacatat cgtggagctc atgatggttc tgagtggggc actatgcttc cgaatgaagg
      361 attcagcctt gaaggtactg tatctgcaca ataaccagct gctggctgga ggattgcatg
      421 cggggaaggt aattaaaggt gaggagatca gcgttgtccc aaatcgggca ctggatgcca
      481 gtctgtcccc tgtaatcctg ggtgttcaag gaggaagcca gtgcctgtcc tgtgggacag
      541 agaaagagcc aattctgaaa cttgagccag tgaacattat ggagctctac ctcgggacca
      601 aggaatcaaa gagcttcacc ttctaccggc gcgatctggg tcttacctct agcttcgagt
      661 ctgctgccta cccaggctgg tttctctgta cctcacccga agctgaccaa cccgtcaggc
      721 tcactcagat ctctgaggac cccgcctggg atgctcccat cacagacttc tactttcaac
      781 agtgtgacta gggctgtgtg gttccccaaa ctccctaagc agaggtggtc gtagaggagc
      841 cccatattgg gtaacttact cctctccttc ctcacaggac tactgcttct gacttctaag
      901 gcacataggc actctcttct cctgtgtccc agtgctggca aatcttctgg tatttggagc
      961 ccaatgtgta gattctttcc aattagatgg tactgcctct ggtatggaat ccaacagaaa
     1021 ccacaaagga ccaacacaga gcaacataaa aatagtcttg ggtgagggag aggtgggaat
     1081 tattcatgca tagtaagatc tgacacagta cctcagaagt cctgccatcc ccatctgtcc
     1141 aggagaacaa gggggcacca agacttttct gactggctgg gccctttccc ttgatcttgc
     1201 tgctgacatc tgctgcctgt ctcatccttg ccttcatttt ctggccttgg actgagagga
     1261 tgatgtcagg atagaggaca gaaggtggcc aggcacactg tcctggtttg aaaccagagg
     1321 tacaataaaa attcatgatt cttgtctcca ctcacataag aagaagcttg tgaacaatag
     1381 gtggggagag attgctacta aataactcat cttgtaattt catcttaatt aaaatatact
     1441 tatctatatt atacatttta aaggtggtct ggagtgttta catcaattgt agccatgtcc
     1501 aagtgagagc aagacaggtg acttttcctt ttatctgtgt ctattacctt ttcccttatg
     1561 gaggtgggtc gtttgtataa taataaaaaa ggaatcaata tagagggaag tgaaacagac
     1621 aaagtttctg gtcatcctca ccatctgctg agtgaaatcc aaactgagct cggctactct
     1681 aagtggcaag gagcagggag caaggggcag accctagaaa agctaggaag aatgtgatgg
     1741 gttcgtgcta gaatctcctg ggtaaggtat ttacagaaga aataaaggaa agaagaaagg
     1801 agtggaggga gggaaaagaa ggaagggaag gaaaggaaag gggaaagact atcctgtgct
     1861 ttaacctggg atggtgacaa actcctggaa ttccaaggaa tcacagctaa cttcctagag
     1921 ggctactgtg ctggtttgaa agtttcctcc tcaaatttat gtccctccca aatctactat
     1981 gatcttaaac gtaaagtgct ggactgatgt cttttgaaaa taatgtagac acagaagggg
     2041 cagaggggaa aggcccacat gagacagagg caaaggttga agtgacttgg ctgccacagc
     2101 cagagggcca cggactgtgc aaaccaccag cagcaagaaa gaggagagaa tccagagagt
     2161 acagatggag agacccctgg ctccagctgc atgtgaaaca gaagatggcc ttgctgggca
     2221 ccaatggaag gagaagccct tggtcctgac aagactcgac acccagtata gaggaatgtc
     2281 agggtgggga ggccagaagg ggtgggtgga tgggtggaag aacaccctca tagaaggagg
     2341 aggggataga ggatttacgg atgggaaacc aggaaagggg ataacatttg aaatgcaaaa
     2401 aaaaaaaatt aaaaatcctc tgggggagaa agggggtggg gaggaaaggt tcctttctag
     2461 ggcatctgag agagcgctgc cttgctgaca ccttagtctc aaccttctgg tcccctgcac
     2521 agaatacact gccactgctc taagttacta agtgtgaagt cattggtgct agcagctgga
     2581 gggactgaat ggagctggta gtggtctcta cttcctcaag tctactccct ctgatgctct
     2641 gccatattac ctctgggcta gtgaaatatg gcagaggtgc cagcaggcta ctacagagag
     2701 tggttctgaa agacacttta atggctttgg agggcctggt ctttctcttc acactggggc
     2761 aagccagttt ctatgctata agcaacccct tagagagagc atatgaggga agctagtcac
     2821 ccatggacaa cagctgaatg tatgagctca ggagcatggc ctgccctgca gccattgcaa
     2881 gccagatgct gtcttgattg cagcctcata agaaactgaa gcagcactgc ccccacccag
     2941 ctgctccaag gcaaaggttt ccccacagaa accccatgaa ctaaacatgt tgcttttaga
     3001 ttctgcagaa agttgataag ctgca
//
