LOCUS       NM_001106554             869 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus interleukin 36, alpha (Il36a), mRNA.
ACCESSION   NM_001106554 XM_001077031 XM_231099
VERSION     NM_001106554.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 869)
  AUTHORS   Vigne S, Palmer G, Lamacchia C, Martin P, Talabot-Ayer D, Rodriguez
            E, Ronchi F, Sallusto F, Dinh H, Sims JE and Gabay C.
  TITLE     IL-36R ligands are potent regulators of dendritic and T cells
  JOURNAL   Blood 118 (22), 5813-5823 (2011)
   PUBMED   21860022
REFERENCE   2  (bases 1 to 869)
  AUTHORS   Martin U, Scholler J, Gurgel J, Renshaw B, Sims JE and Gabel CA.
  TITLE     Externalization of the leaderless cytokine IL-1F6 occurs in
            response to lipopolysaccharide/ATP activation of transduced bone
            marrow macrophages
  JOURNAL   J Immunol 183 (6), 4021-4030 (2009)
   PUBMED   19717513
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474001.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001077031.1, XM_231099.3.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..869
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p13"
     gene            1..869
                     /gene="Il36a"
                     /gene_synonym="Il1f6"
                     /note="interleukin 36, alpha"
                     /db_xref="GeneID:296541"
                     /db_xref="RGD:1306869"
     exon            1..119
                     /gene="Il36a"
                     /gene_synonym="Il1f6"
                     /inference="alignment:Splign:2.1.0"
     exon            120..177
                     /gene="Il36a"
                     /gene_synonym="Il1f6"
                     /inference="alignment:Splign:2.1.0"
     CDS             162..644
                     /gene="Il36a"
                     /gene_synonym="Il1f6"
                     /note="interleukin 1 family, member 6"
                     /codon_start=1
                     /product="interleukin-36 alpha"
                     /protein_id="NP_001100024.1"
                     /db_xref="GeneID:296541"
                     /db_xref="RGD:1306869"
                     /translation="MNKDKELSAATPWFRHIQDLSSRVWVLQDNILTAVPRKEQTVPV
                     TITLLPCQYLDTLEKNKGDPMYLGVKKPQSCLSCTKNGEQPVLQLREGNILDMYHQKE
                     RVKASLFYHKKSGTTSTFESAAFPGWFIAVCSKGSCPLVLTQELGKTFITDFEMTVVH
                     "
     exon            178..291
                     /gene="Il36a"
                     /gene_synonym="Il1f6"
                     /inference="alignment:Splign:2.1.0"
     exon            292..431
                     /gene="Il36a"
                     /gene_synonym="Il1f6"
                     /inference="alignment:Splign:2.1.0"
     exon            432..645
                     /gene="Il36a"
                     /gene_synonym="Il1f6"
                     /inference="alignment:Splign:2.1.0"
     exon            646..869
                     /gene="Il36a"
                     /gene_synonym="Il1f6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 taatctcctc ccttcatgtt ttggataaaa ggcctggacc ctagcagagc ttgtcagaga
       61 agctgagcac agtagtggct gtagttctgt agtgtgcaga tacattcctc tgcaatcagg
      121 atcagtctgc agattggcag ttcagaaaca acatcaccat aatgaataag gataaagaac
      181 taagtgcagc aacaccttgg tttagacata ttcaggatct tagtagtcgt gtgtgggtcc
      241 ttcaagacaa tattcttact gcagtcccaa ggaaagagca aacggttcca gtcactatca
      301 ccttactccc atgccaatat ctggacactc ttgagaagaa caaaggggat cccatgtacc
      361 tgggagtgaa gaaacctcaa agttgtctgt cctgcacaaa gaatggggag cagcctgtac
      421 tacaacttcg ggaagggaac atactggata tgtaccacca gaaggaacgt gtaaaagcct
      481 ctctcttcta tcacaagaag agtggtacaa cctctacatt cgagtctgca gccttccctg
      541 gttggttcat tgctgtctgc tccaaaggga gctgcccact cgttttgacc caagaacttg
      601 ggaaaacctt catcactgat tttgagatga ctgtagtaca ttaagattgc tctgcagcac
      661 tctctgaaga tctctcggat tctaacaagc aaccaaacac acccccaaca aaatacaaga
      721 ctgaaaagaa agctgagccc tccctgggct tttttccctt ggcaggtgga tcagatgcag
      781 aacttcttac catgttttca tccaaagcat ttactgatgg tttttacaag aagaaaacgt
      841 ttttaattaa aatcatttat ctcacttgc
//
