LOCUS       NM_001257278            2442 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus interleukin 31 receptor A (Il31ra), mRNA.
ACCESSION   NM_001257278 XM_002725901
VERSION     NM_001257278.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2442)
  AUTHORS   denDekker,A.D., Xu,X., Vaughn,M.D., Puckett,A.H., Gardner,L.L.,
            Lambring,C.J., Deschenes,L. and Samuelson,D.J.
  TITLE     Rat Mcs1b is concordant to the genome-wide association-identified
            breast cancer risk locus at human 5q11.2 and MIER3 is a candidate
            cancer susceptibility gene
  JOURNAL   Cancer Res 72 (22), 6002-6012 (2012)
   PUBMED   22993404
REFERENCE   2  (bases 1 to 2442)
  AUTHORS   Shen,M., Siu,S., Byrd,S., Edelmann,K.H., Patel,N., Ketchem,R.R.,
            Mehlin,C., Arnett,H.A. and Hasegawa,H.
  TITLE     Diverse functions of reactive cysteines facilitate unique
            biosynthetic processes of aggregate-prone interleukin-31
  JOURNAL   Exp Cell Res 317 (7), 976-993 (2011)
   PUBMED   21182835
REFERENCE   3  (bases 1 to 2442)
  AUTHORS   Perrigoue,J.G., Zaph,C., Guild,K., Du,Y. and Artis,D.
  TITLE     IL-31-IL-31R interactions limit the magnitude of Th2
            cytokine-dependent immunity and inflammation following intestinal
            helminth infection
  JOURNAL   J Immunol 182 (10), 6088-6094 (2009)
   PUBMED   19414760
REFERENCE   4  (bases 1 to 2442)
  AUTHORS   Ghilardi,N., Li,J., Hongo,J.A., Yi,S., Gurney,A. and de
            Sauvage,F.J.
  TITLE     A novel type I cytokine receptor is expressed on monocytes, signals
            proliferation, and activates STAT-3 and STAT-5
  JOURNAL   J Biol Chem 277 (19), 16831-16836 (2002)
   PUBMED   11877449
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from JQ013736.1.
            
            On Feb 25, 2013 this sequence version replaced NM_001257278.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: JQ013736.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5756307,
                                           SAMEA5760383 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2442              JQ013736.1         1-2442
FEATURES             Location/Qualifiers
     source          1..2442
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q14"
     gene            1..2442
                     /gene="Il31ra"
                     /note="interleukin 31 receptor A"
                     /db_xref="GeneID:688622"
                     /db_xref="RGD:1586478"
     exon            1..50
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     exon            51..129
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..2231
                     /gene="Il31ra"
                     /note="interleukin-31 receptor subunit alpha"
                     /codon_start=1
                     /product="interleukin-31 receptor subunit alpha precursor"
                     /protein_id="NP_001244207.1"
                     /db_xref="GeneID:688622"
                     /db_xref="RGD:1586478"
                     /translation="MWILALWLLPLLCKFSLAGLPPKPENISCIFYFDRNLTCTWSPE
                     KETNDTSYTVRMTYSYGKSSCTVNATEASCSFPSYCAIAPDNCSVEVEAQNNDGKAIS
                     AITYWDLSSIVKTEPPIILSVNPISNRMFQIRWEPWEKIHVFPLTCMIQFRTVNSSHW
                     TEVNLEDCERVFNLTGLQAFTQYVLALRFRFSDSRYWSKWSKEETRMTMEEVPHVLDL
                     WRILEPADVNGDRKVLLLWKKARGAPVLEKTFGYNIQYSAENSTNVTEINSITTQHYE
                     LLLLGQTHCVSVTSFNSLGKSQEAILRIPDAHEETFQCINGMQAYIAEPLLVVNWQSS
                     IPEVDTWIVEWIPETAESKFPALCWESVSRVTNWTIEQDKLEPFTCYNISVYPVLGHH
                     VGEPYSIQAYAKEKAPTSGPNTTVNNIGLKTAVVTWKEIPKSIRNGFIHNYTIFYQAE
                     GGKKLSKTVNSHTLQYDLESLTRRTSYTVSVMASTRAGGTIGSSINFKTSSISVFEIV
                     LLTTLIGGGLLLLSIKTVTFGLRKPNSRLTHLCCPDVPNPAESSLATWFGDDFKKKSN
                     MKETENSGNTEDQVLKPCPVPADLTDKLVVNFENFLEVVSTAEAGKGQESVLGGEANE
                     YVTSPSRADCPPGKSFKEPSVLTEAASEDCHSRTPGMAEETYSELDNQPLPSCQSPGL
                     EPPCEERAQNPYLKNSVTTREFLMHENIPEYSKGEI"
     exon            130..247
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     exon            248..411
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     exon            412..554
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     exon            555..708
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     exon            709..788
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     exon            789..1005
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1191
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     exon            1192..1293
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1440
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     exon            1441..1581
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     exon            1582..1675
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     exon            1676..1760
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
     exon            1761..2442
                     /gene="Il31ra"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tggtgctggg aactgtttaa agcttcattt tagactctcg cagataacag cctctaggtg
       61 tgaattctgg gacaatgtgg atcttggcac tgtggctact ccctctactc tgcaaattca
      121 gcctagcagg tctaccacct aagccagaga acatttcctg catcttttac tttgacagga
      181 atctgacttg cacttggagt ccagagaagg aaaccaatga taccagctac accgtgagga
      241 tgacttactc ctatgggaag agcagttgca ctgttaatgc tacagaggct tcgtgttctt
      301 ttccctccta ctgtgcaata gccccagaca actgcagtgt tgaagtagaa gctcaaaaca
      361 acgatggtaa agctatatct gccatcacat attgggattt aagctccata gtgaaaaccg
      421 aaccacctat aattttaagt gtgaatccaa tttcaaatag aatgttccag atacgatggg
      481 aaccctggga aaagattcat gtgtttcctt taacatgcat gattcagttc aggactgtca
      541 acagtagcca ctggacggaa gtcaatttag aggactgcga acgggtcttc aacctcacag
      601 ggcttcaggc tttcacacaa tatgtcctgg ctctacgatt caggttcagt gactcaagat
      661 actggagcaa gtggagcaaa gaagaaacca gaatgactat ggaggaagtt ccccatgtcc
      721 tggacctgtg gagaattctg gagccagcag atgtgaatgg agacaggaaa gtgttactgc
      781 tgtggaagaa ggcgagagga gccccagtct tggagaaaac atttggctac aacatacagt
      841 actctgcaga aaacagcact aacgtcacgg agataaacag catcactacc cagcactatg
      901 aactgcttct gttgggccag acgcactgtg tgtctgtgac ttcttttaac tctcttggca
      961 agtcccaaga ggccatactg aggatcccag atgcccatga ggagaccttc cagtgcatca
     1021 acggcatgca ggcctacata gctgagcccc tgctggtggt gaactggcag agttccattc
     1081 ctgaggtgga cacttggata gtggagtgga tcccagaaac ggctgagtcg aagttccctg
     1141 ctctttgctg ggaatctgtg tctcgggtca ccaactggac catcgagcaa gataaattag
     1201 aacctttcac atgctataat atatcagtgt atccagtgtt gggacaccac gtaggagagc
     1261 catattccat ccaagcttat gccaaagaaa aagctccaac atctggtccc aataccacgg
     1321 tgaacaacat tggtttgaag acagccgtgg tcacatggaa agagattccc aagagtatta
     1381 gaaatggatt tatccacaat tacacgatat tttaccaagc tgaaggtgga aaaaaactct
     1441 ccaagactgt taactcccac acccttcagt atgacctgga gtctctgaca cgaaggacct
     1501 cttacactgt ttctgtcatg gccagcacca gagctggagg taccatcggg tcgagcataa
     1561 acttcaagac atcgtcaatc agtgtctttg aaattgtcct tctaacgact ctaattggag
     1621 gaggccttct tctacttagc atcaaaacag tgacttttgg tctcaggaag ccaaacagcc
     1681 gattgactca tctgtgctgt cctgatgttc ccaaccctgc tgaaagtagt ttagctacct
     1741 ggtttggaga tgatttcaag aagaagtcaa atatgaagga gactgaaaac tctgggaaca
     1801 cagaagacca ggtcctaaaa ccatgtcctg tccccgctga cctcactgat aagctggtag
     1861 tgaactttga gaattttctg gaagtagttt cgacagcgga agctggaaag ggtcaggaga
     1921 gcgttttggg aggagaagcg aatgagtatg tgacctcccc atccagggct gactgtcccc
     1981 cagggaaaag ttttaaggag ccctcagttt taactgaggc tgcttctgaa gactgccata
     2041 gccggactcc gggaatggcg gaagagacat actcagaact tgacaaccaa cctttacctt
     2101 cctgtcagag tccaggactg gagcccccct gtgaagagcg agctcagaat ccatatctga
     2161 aaaattcagt gacaaccagg gagtttctta tgcatgaaaa tattccagag tacagcaagg
     2221 gagaaatcta agtgctgcta tggtctggaa ccctcggaga ctgaatggat ctcttcccta
     2281 gcaaagacat ggaaacttcc agaagcctcc ttctaccctg gcctgttcag tttgctgctg
     2341 agctgcccag aaattggtga tgcagctgtg gacttatgtc gggaagaatg gaatgcttta
     2401 cagggagaca gaagttactt ctgtgtgctc tcacagacgc cc
//
