LOCUS       NM_001415057            3091 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus interleukin 17 receptor B (Il17rb), transcript
            variant 2, mRNA.
ACCESSION   NM_001415057 XM_006252603
VERSION     NM_001415057.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3091)
  AUTHORS   Beale,J., Jayaraman,A., Jackson,D.J., Macintyre,J.D.R.,
            Edwards,M.R., Walton,R.P., Zhu,J., Man Ching,Y., Shamji,B.,
            Edwards,M., Westwick,J., Cousins,D.J., Yi Hwang,Y., McKenzie,A.,
            Johnston,S.L. and Bartlett,N.W.
  TITLE     Rhinovirus-induced IL-25 in asthma exacerbation drives type 2
            immunity and allergic pulmonary inflammation
  JOURNAL   Sci Transl Med 6 (256), 256ra134 (2014)
   PUBMED   25273095
REFERENCE   2  (bases 1 to 3091)
  AUTHORS   Rickel,E.A., Siegel,L.A., Yoon,B.R., Rottman,J.B., Kugler,D.G.,
            Swart,D.A., Anders,P.M., Tocker,J.E., Comeau,M.R. and Budelsky,A.L.
  TITLE     Identification of functional roles for both IL-17RB and IL-17RA in
            mediating IL-25-induced activities
  JOURNAL   J Immunol 181 (6), 4299-4310 (2008)
   PUBMED   18768888
REFERENCE   3  (bases 1 to 3091)
  AUTHORS   Tian,E., Sawyer,J.R., Largaespada,D.A., Jenkins,N.A., Copeland,N.G.
            and Shaughnessy,J.D. Jr.
  TITLE     Evi27 encodes a novel membrane protein with homology to the IL17
            receptor
  JOURNAL   Oncogene 19 (17), 2098-2109 (2000)
   PUBMED   10815801
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On Dec 20, 2022 this sequence version replaced XM_006252603.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643287.32123.1,
                                           SRR26643288.54912.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-158               JAXUCZ010000016.1  5200500-5200657     c
            159-183             JAXUCZ010000016.1  5198549-5198573     c
            184-324             JAXUCZ010000016.1  5197709-5197849     c
            325-452             JAXUCZ010000016.1  5195949-5196076     c
            453-579             JAXUCZ010000016.1  5195288-5195414     c
            580-627             JAXUCZ010000016.1  5194227-5194274     c
            628-770             JAXUCZ010000016.1  5192787-5192929     c
            771-836             JAXUCZ010000016.1  5192379-5192444     c
            837-936             JAXUCZ010000016.1  5191327-5191426     c
            937-1032            JAXUCZ010000016.1  5189878-5189973     c
            1033-3091           JAXUCZ010000016.1  5186961-5189019     c
FEATURES             Location/Qualifiers
     source          1..3091
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p16"
     gene            1..3091
                     /gene="Il17rb"
                     /note="interleukin 17 receptor B"
                     /db_xref="GeneID:306247"
                     /db_xref="RGD:1311392"
     exon            1..158
                     /gene="Il17rb"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..1598
                     /gene="Il17rb"
                     /note="isoform 2 precursor is encoded by transcript
                     variant 2"
                     /codon_start=1
                     /product="interleukin-17 receptor B isoform 2 precursor"
                     /protein_id="NP_001401986.1"
                     /db_xref="GeneID:306247"
                     /db_xref="RGD:1311392"
                     /translation="MLLVLLSLAAMCRSALSREPTIQCGSETGPSPEWMVQHTLTPGD
                     LRDLRVELVKTSVATEEFSILMNISWILRADASIRLLKATKICVSGKNNMHSYSCVRC
                     NYTETFQSQTRPSGGKWIFSYVGFPVELSTLYLIGAHNIPNANMNEDSPSLSVNFTSP
                     GCLNHVMKYKKQCIEAGSLWDPNITACKKNEKTVEVNFTTNSLGNRYMVLIRRDTMLG
                     VSIVLENKLTRTSVVIPVNDESEGALVELTPYLHTCDNDCIRRKGTVVLCSETSAPFP
                     PDDNRSMLRGWLPLLLVLLVATWVLAVGIYLTWRQGRSTKTSFPITAMLLPLVKVLVV
                     YPSEICFHHTVCRFTDFLQNYCRSEVILEKWQKKKIAEMGPVQWLTTQKQAADKVVFL
                     LPSDAPSLCDSACGHKEGSATENSQDLFPLAFNLFCSDFSSQTHLHKYLVVYLGGADL
                     KGDYNALRVCPQYHLMKDAPAFHTELLKATQSMPLKKRPQACHGSCSPL"
     exon            159..183
                     /gene="Il17rb"
                     /inference="alignment:Splign:2.1.0"
     exon            184..324
                     /gene="Il17rb"
                     /inference="alignment:Splign:2.1.0"
     exon            325..452
                     /gene="Il17rb"
                     /inference="alignment:Splign:2.1.0"
     exon            453..579
                     /gene="Il17rb"
                     /inference="alignment:Splign:2.1.0"
     exon            580..627
                     /gene="Il17rb"
                     /inference="alignment:Splign:2.1.0"
     exon            628..770
                     /gene="Il17rb"
                     /inference="alignment:Splign:2.1.0"
     exon            771..836
                     /gene="Il17rb"
                     /inference="alignment:Splign:2.1.0"
     exon            837..936
                     /gene="Il17rb"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1032
                     /gene="Il17rb"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..3091
                     /gene="Il17rb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcggaggcg gagcccggag agttgccgcg ggctcctgga taagaggacc ctggatctcc
       61 cgccccagct ccgcgtggtg gtgggcggtg gccgggccat gttgctagtg ttgctgagcc
      121 tggctgctat gtgcaggagc gccctgtccc gagagccgac tattcagtgt ggctctgaga
      181 cagggccatc tccagagtgg atggtccaac atacactcac tccgggagac ctgagggacc
      241 tccgagtgga acttgtcaag acaagtgtgg caacagagga gttttcaatt ctgatgaaca
      301 taagctggat actccgggca gacgccagca tccgcttgtt gaaggccacc aagatctgcg
      361 tgagtggcaa aaacaacatg cattcataca gctgcgtgag gtgcaactac acagagacct
      421 tccaaagcca gaccagacct tccggcggca aatggatctt ctcctatgtc ggcttccctg
      481 tggagctgag cacgctctat ctcatcgggg cccataacat ccccaatgct aacatgaacg
      541 aggacagccc ttctttgtct gtgaacttca cctcgccagg ctgcctaaac catgtaatga
      601 aatataagaa gcagtgcatt gaagcaggaa gcctgtggga cccaaacatc acagcttgta
      661 agaagaatga gaagaccgtt gaagtgaatt ttacaaccaa ttcccttgga aacagataca
      721 tggttctcat tcgacgggac acaatgttgg gggtttctat agtgctggag aacaaactga
      781 cgaggacatc tgtagtcatt ccggtcaatg atgagagtga aggtgccttg gttgagctga
      841 ccccatattt acacacctgc gacaatgact gcattcgacg caaagggaca gtggtgcttt
      901 gctcagagac aagtgctccc ttccctccag atgacaacag aagcatgctg agaggctggc
      961 tgcctctcct cctggtgctg ctggtggcta catgggtgct ggcagttggg atctacctaa
     1021 cttggaggca aggaaggagc acaaagacat cttttcctat caccgccatg ctcctgcccc
     1081 tcgttaaggt cctggtggtt tacccatccg agatatgttt ccatcacaca gtctgtcgct
     1141 ttactgactt tcttcaaaac tactgcagaa gtgaggtcat ccttgaaaaa tggcagaaaa
     1201 agaaaatcgc cgagatgggg cccgtgcagt ggcttaccac tcagaagcaa gcagcagata
     1261 aagtcgtctt ccttcttccc agtgacgccc cttccctttg tgacagtgcc tgtggccaca
     1321 aggagggcag tgccacggag aattctcagg atctgttccc tcttgccttt aacctctttt
     1381 gtagcgattt cagcagccag actcatctgc acaaatacct ggtggtctat cttgggggag
     1441 cagacctcaa aggggactat aatgccctga gagtctgccc ccagtatcat ctcatgaagg
     1501 acgccccagc tttccacaca gaacttctca aggctacgca aagcatgccg ctgaagaaac
     1561 ggccacaggc ctgccacggc agctgttcac ccttgtagtc cacccaggag gagagggacc
     1621 tgaagccttc ctactctacc ttccagtgac aaaacacctt gtgacgaccc tgaaatgtac
     1681 tgtataggct gtgtgtaggt agtgctatgt acagaacttg ctctaaaact ggagtttaca
     1741 gtcagagctt gagcacagat gcctgaggct agtcattagc tggctttatg aagacattag
     1801 tgagtggaac ctaaatgttt gaatataccc aaagccgggt gctgattatc accatgaact
     1861 cagcactctg gccaggaagg aatgaggcat ttcccagtca ggtgtctggt cttacactgc
     1921 ccacgctcta tgctgcacat aggactgtgg actcctgaag attttaatct attaatgagt
     1981 aacccctctg ggaggctctc actaatgtgt agcttcctaa gagaacaagc ctattacaca
     2041 cacaagctgc ctgaccagat gatccagtgt ctatgtaacc actgcgctgt ctgatgtttg
     2101 cacagtgctt tccctcacca cacttttgga caggtaacct ttacttttta tcttatgagt
     2161 gccaggaatt gaacccaggg tattatgcgc actagacaaa cgccctgcca ctgaaataca
     2221 tccccgtccc tcacaggtgt cacaccttta atccagcact caagtagaag aggcaggagg
     2281 atctctgtct gaggccagcc agagacacac agtggggctc cgtctcaaat gaacaagttg
     2341 ttacccataa atctagtgtc tacttttgtc cagttaacct gtccactgtt gtggttccca
     2401 gagttcttgg ttattaccta agatttcctg ttcaaaacta attcttaaag tgaaattagc
     2461 tctcttgaag taattaatct tctctgtaat caatcgctta aataaaaaac taccaagaag
     2521 gaaggacagc tcacagactc agctctggac tcgggttgtt tccagcaccc acacggctgc
     2581 tcataaccat cttagctcta gtttgggaat ccgacaacct tctttggctt ttgaggacac
     2641 tctacatgca ttttaaaaac acactgtata tatcgcagtg ttttgcttgc atgtatgtct
     2701 gtgtaccatg tgtgcttggt gcctgaggtc agattaccag cttggtgctg gattacctgg
     2761 aactggaatt acagacacat gtgagccacc aggtggatgc tgggaatcaa acctgggtct
     2821 tctgcaagaa caaatgctct ttaactgctg aactctctct ttacaccccc taacataaat
     2881 aaatcttatt taaaaacaaa aatgaaaaca aaaaaatctg accagaaaca gtaacagtat
     2941 atagacttgt aacatctttg agccttctag attgttactt tctcaaagca gctttttctt
     3001 aatgtagaaa ctacaaaaaa atgtatataa tagcatatgt atttgtctag tatggcttca
     3061 tacagcataa taaatctgtt ttgtaatggg a
//
