LOCUS       NM_053789                688 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus interleukin 17B (Il17b), mRNA.
ACCESSION   NM_053789 XM_001062716 XM_341621
VERSION     NM_053789.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 688)
  AUTHORS   Yamaguchi,Y., Fujio,K., Shoda,H., Okamoto,A., Tsuno,N.H.,
            Takahashi,K. and Yamamoto,K.
  TITLE     IL-17B and IL-17C are associated with TNF-alpha production and
            contribute to the exacerbation of inflammatory arthritis
  JOURNAL   J Immunol 179 (10), 7128-7136 (2007)
   PUBMED   17982105
REFERENCE   2  (bases 1 to 688)
  AUTHORS   Li,H., Chen,J., Huang,A., Stinson,J., Heldens,S., Foster,J.,
            Dowd,P., Gurney,A.L. and Wood,W.I.
  TITLE     Cloning and characterization of IL-17B and IL-17C, two new members
            of the IL-17 cytokine family
  JOURNAL   Proc Natl Acad Sci U S A 97 (2), 773-778 (2000)
   PUBMED   10639155
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On or before Dec 19, 2009 this sequence version replaced
            XM_001062716.1, XM_341621.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.2456249.1,
                                           SRR22582424.1451672.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN09767679
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-62                JAXUCZ010000018.1  57411532-57411593
            63-352              JAXUCZ010000018.1  57413483-57413772
            353-688             JAXUCZ010000018.1  57415568-57415903
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.1"
     gene            1..688
                     /gene="Il17b"
                     /note="interleukin 17B"
                     /db_xref="GeneID:116472"
                     /db_xref="RGD:620614"
     exon            1..62
                     /gene="Il17b"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..584
                     /gene="Il17b"
                     /codon_start=1
                     /product="interleukin-17B precursor"
                     /protein_id="NP_446241.1"
                     /db_xref="GeneID:116472"
                     /db_xref="RGD:620614"
                     /translation="MDWPHSLLFLLAISIFLVPSQPRNTKGKRKGQGRPGPLAPGPHQ
                     VPLDLVSRVKPYARMEEYERNLGEMVAQLRNSSEPAKKKCEVNLQLWLSNKRSLSPWG
                     YSINHDPSRIPEDLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPQPPRP
                     GPCRQRVVMETIAVGCTCIF"
     exon            63..352
                     /gene="Il17b"
                     /inference="alignment:Splign:2.1.0"
     exon            353..688
                     /gene="Il17b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggttcctg gccggtggca gctgcaggct gacttaatgg gatggactgg ccacacagcc
       61 tgctcttcct tcttgccatc tccatcttcc tggtgccaag ccagccccgg aacaccaaag
      121 gcaaaaggaa ggggcaaggg aggcctggcc ccttggcccc tgggcctcac caggtgccgc
      181 tggacctggt gtctcgagta aagccctacg cccgaatgga agagtacgag aggaaccttg
      241 gcgagatggt ggcccagctg aggaacagct ctgagccagc caagaagaag tgtgaagtca
      301 acttgcagct gtggttatcc aacaagagaa gcctgtctcc ctggggctac agcatcaatc
      361 acgaccccag ccgcatcccg gaggacttgc ctgaggcgcg gtgcctatgt ttgggttgcg
      421 tgaacccctt caccatgcag gaggaccgta gcatggtgag cgtgccagtg ttcagccagg
      481 tgccagtgcg ccgccgcctc tgtccgcaac ctcctcggcc cgggccctgc cgccagcgtg
      541 ttgtcatgga gaccatcgct gtgggttgca cctgcatctt ctgagccacc aaccctcaac
      601 caggtggcta ctgcaacgat cctccctccc tgcacccact gtgaccctca aggctgataa
      661 acagtaaacg ttgttctttg taaaggaa
//
