LOCUS       NM_001008765            2125 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus interferon gamma induced GTPase (Igtp), mRNA.
ACCESSION   NM_001008765 XM_001075220 XM_220451
VERSION     NM_001008765.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2125)
  AUTHORS   Han L, Ni Y, Cao M, Zhu L, Dai A, Xu Z, Liu X, Chen R, Ning X and
            Ke K.
  TITLE     A New Role Discovered for IGTP: The Protective Effect of IGTP in
            ICH-Induced Neuronal Apoptosis
  JOURNAL   Cell Mol Neurobiol 36 (5), 713-724 (2016)
   PUBMED   26242173
  REMARK    GeneRIF: Interferon gamma-induced GTPase was also observed to be
            co-localized with PCNA in astrocytes and active-caspase-3 in
            neurons
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC129105.1.
            
            On or before May 31, 2008 this sequence version replaced
            XM_220451.4, XM_001075220.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC129105.1, CK367508.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2125
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..2125
                     /gene="Igtp"
                     /note="interferon gamma induced GTPase"
                     /db_xref="GeneID:303163"
                     /db_xref="RGD:1306896"
     exon            1..180
                     /gene="Igtp"
                     /inference="alignment:Splign:2.1.0"
     exon            181..406
                     /gene="Igtp"
                     /inference="alignment:Splign:2.1.0"
     CDS             368..1693
                     /gene="Igtp"
                     /note="Ac2-233"
                     /codon_start=1
                     /product="interferon gamma induced GTPase"
                     /protein_id="NP_001008765.1"
                     /db_xref="GeneID:303163"
                     /db_xref="RGD:1306896"
                     /translation="MDLVMKLPQMIRKVFTPFINMAKPLKPPLFKSITAGESSYSSQN
                     SSSPEVIEKVGKAVAEGDLQKVIYTVKEEMQSKSRYTVKIAVTGDSGNGMSSFVNALR
                     LIGHEEEDSAPTGVVRTTQKPACYSSFHFPYVELWDLPGTGVTAQSMESYLDEMQFSA
                     YDLIIIIASEQFSSNHVKLAEAMQRMRKRFYVVWTKLDRDISTSTFPEPQLLQSIQKN
                     IRENLQKAQVRDPPIFLVSCFSPSFHDFLDLRETLRKDIHNIRYRDPLETLSQVCDKC
                     INNKALSLKEDLMFTKHLEAAVSPPYDIADLERSLDTYQKLFGVDNESLRRVAQSTGR
                     PEMSTRALQFQDLIKMDRRLRLMMCFVVNILLRVLGSPWWFGLWDVVTRYFRHQRQKR
                     IIEIVAKNTKTSLRRALEDYTLPPEILCEGSGVPSSGIQAASGSFCIEP"
     exon            407..2108
                     /gene="Igtp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgcatcagg gccaagatag agcagggtct gagaggtaac ccaggagctc aggctggcct
       61 tcggaagctc caggctcttc tagtcgctct tccccacagg accctgcccc ttcaaacttc
      121 tgttttcttc ctcctggctg tcctgggccc ggattgcagt tttgtaaggc ttctgaacag
      181 gttctgaaga agagtaaaga tcacaaggcc tgtaacagac ccacgggttc aggtccacgg
      241 gtatagacct tcatactcca ttaagtcgaa gggagaagga agaaccagag gaacaccagc
      301 tcagccattt gagttaagac tacagagtgt tcacacagac agcagagagc tgtgtagaga
      361 gcgtcccatg gatttagtca tgaagttgcc acaaatgata cggaaggttt ttaccccttt
      421 cataaacatg gcgaaacctc tcaagccgcc attgtttaaa tccatcactg ctggtgagtc
      481 atcctatagc agccagaact cttcttctcc agaagtcatt gagaaggtcg gtaaggctgt
      541 ggcagagggg gatttacaga aagtgatata cacagtcaaa gaggaaatgc agagtaagtc
      601 tagatacacg gtaaaaatcg ccgtgactgg ggactctggc aatggcatgt catctttcgt
      661 caacgccctt aggctcattg gacatgagga ggaggattca gctcccactg gggtggtgag
      721 gaccacccag aaaccagcct gttactcctc tttccacttt ccctatgtgg agctgtggga
      781 cctgcctggc accggggtca cagcccagag catggagagc tacctggatg agatgcagtt
      841 cagcgcatat gaccttatca tcatcattgc ttctgagcag ttcagctcga atcatgtgaa
      901 gctggccgaa gccatgcaga ggatgagaaa gaggttctat gtcgtctgga ccaagctgga
      961 cagggacatc agcacaagta ccttccctga accccagctc ctgcagagta tccaaaagaa
     1021 tatcagggag aatctccaga aggctcaggt gagggacccc cccatatttc tggtctcctg
     1081 ctttagtcca tcttttcacg acttcctaga ccttagagag acactgcgaa aagacatcca
     1141 caacatcagg tacagagatc ccttagagac cctttctcaa gtctgcgaca agtgcatcaa
     1201 caataaggcg ctctctctga aggaggacct gatgttcacg aaacacctgg aggcagctgt
     1261 cagccccccg tatgatattg ctgacctgga gaggagtctg gacacctacc agaagctctt
     1321 tggtgtggat aatgagtcac ttaggagggt agctcagagt acagggagac cagagatgag
     1381 caccagggcc ttgcagttcc aggacttgat caagatggac aggagactga ggttgatgat
     1441 gtgttttgtc gtgaacatac tcctcagggt tcttggaagt ccatggtggt tcggcttgtg
     1501 ggatgtcgtt acccgatact tcagacacca gagacagaag cgcatcattg aaatagttgc
     1561 taagaacacc aagacctcct tgaggagagc tctagaggac tatacacttc ctcctgaaat
     1621 cctttgtgaa gggtctggcg taccctcaag tggaatccag gctgcctcag ggtctttttg
     1681 catagagccc tagctattcg ccagaaaaca agaactgcag caacaccttg taacaatgct
     1741 taataaattt agaggacttc aggaaaccgc tctccttcct gtcttcaatt ctaataccct
     1801 gttccttcaa agtgtcaagt acttgccgag acaatcagcc aagccttgtt agctcggtac
     1861 ttagattctt atgctttcag tcttcttggt aacgcatgtt taaatcaaat cttttccctc
     1921 gggctggaga gatggcttag tagttaagag taatggctcc tcttccaggg gtcctgagtt
     1981 caattcccag caaccacgtg gtggctcaca accatctgta atgggatctg atgccctctt
     2041 ctgatctatc tgaagacaca gtgtgttcat atataaaaat aaataaataa atgaatcttt
     2101 aaaaaaaaaa aaaaaaaaaa aaaaa
//
