LOCUS       NM_001014787            2226 bp    mRNA    linear   ROD 26-APR-2024
DEFINITION  Rattus norvegicus immunoglobulin superfamily, member 8 (Igsf8),
            mRNA.
ACCESSION   NM_001014787 XM_222900
VERSION     NM_001014787.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2226)
  AUTHORS   Apostolo,N., Smukowski,S.N., Vanderlinden,J., Condomitti,G.,
            Rybakin,V., Ten Bos,J., Trobiani,L., Portegies,S., Vennekens,K.M.,
            Gounko,N.V., Comoletti,D., Wierda,K.D., Savas,J.N. and de Wit,J.
  TITLE     Synapse type-specific proteomic dissection identifies IgSF8 as a
            hippocampal CA3 microcircuit organizer
  JOURNAL   Nat Commun 11 (1), 5171 (2020)
   PUBMED   33057002
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2226)
  AUTHORS   Ray,A. and Treloar,H.B.
  TITLE     IgSF8: a developmentally and functionally regulated cell adhesion
            molecule in olfactory sensory neuron axons and synapses
  JOURNAL   Mol Cell Neurosci 50 (3-4), 238-249 (2012)
   PUBMED   22687584
REFERENCE   3  (bases 1 to 2226)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (bases 1 to 2226)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 2226)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   6  (bases 1 to 2226)
  AUTHORS   Werner,H.B., Kuhlmann,K., Shen,S., Uecker,M., Schardt,A.,
            Dimova,K., Orfaniotou,F., Dhaunchak,A., Brinkmann,B.G., Mobius,W.,
            Guarente,L., Casaccia-Bonnefil,P., Jahn,O. and Nave,K.A.
  TITLE     Proteolipid protein is required for transport of sirtuin 2 into CNS
            myelin
  JOURNAL   J Neurosci 27 (29), 7717-7730 (2007)
   PUBMED   17634366
REFERENCE   7  (bases 1 to 2226)
  AUTHORS   Stipp,C.S., Kolesnikova,T.V. and Hemler,M.E.
  TITLE     EWI-2 is a major CD9 and CD81 partner and member of a novel Ig
            protein subfamily
  JOURNAL   J Biol Chem 276 (44), 40545-40554 (2001)
   PUBMED   11504738
REFERENCE   8  (bases 1 to 2226)
  AUTHORS   Clark,K.L., Zeng,Z., Langford,A.L., Bowen,S.M. and Todd,S.C.
  TITLE     PGRL is a major CD81-associated protein on lymphocytes and
            distinguishes a new family of cell surface proteins
  JOURNAL   J Immunol 167 (9), 5115-5121 (2001)
   PUBMED   11673522
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Mar 18, 2021 this sequence version replaced NM_001014787.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC092192.1, SRR22582416.37573.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-73                JAXUCZ010000013.1  87302767-87302839
            74-176              JAXUCZ010000013.1  87303534-87303636
            177-554             JAXUCZ010000013.1  87307031-87307408
            555-1016            JAXUCZ010000013.1  87308442-87308903
            1017-1424           JAXUCZ010000013.1  87309207-87309614
            1425-1838           JAXUCZ010000013.1  87309724-87310137
            1839-1969           JAXUCZ010000013.1  87310384-87310514
            1970-2226           JAXUCZ010000013.1  87310685-87310941
FEATURES             Location/Qualifiers
     source          1..2226
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q24"
     gene            1..2226
                     /gene="Igsf8"
                     /note="immunoglobulin superfamily, member 8"
                     /db_xref="GeneID:304979"
                     /db_xref="RGD:1311500"
     exon            1..73
                     /gene="Igsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            74..176
                     /gene="Igsf8"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..1954
                     /gene="Igsf8"
                     /codon_start=1
                     /product="immunoglobulin superfamily member 8 precursor"
                     /protein_id="NP_001014787.1"
                     /db_xref="GeneID:304979"
                     /db_xref="RGD:1311500"
                     /translation="MGVPSPTPLSSLLLLLLILGARCYARQVHVPKGPLYRVAGTAVS
                     ISCNVSDYEGPSQQDFEWFMYRPEAPATSLGIISTKDSQFSYAVFGPRVASGDLQVQR
                     LKGDSVVLKIARLQAQDSGFYECYTPSTDTQYLGNYSAKVELRVLPDELQVSAAPPGP
                     RGRQVATSPSRLTVHEGQELALGCLAQTKTKKHTHLSVSFGRAIPEAPVGRATLQEVV
                     GLRSDMAVEAGAPYAERLVAGELRLSKEGTDRYRMVVGGAQAGDSGTYHCTAAEWIQD
                     PDGSWVQVAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAG
                     RHAAYSVGWEMAPAGAPGPGRLVAQLDTEGIGSLGPGYEDRHIAMEKVASRTYRLRLE
                     AARPADAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGGTV
                     YRGETASLLCNISVRGGPPGLRLAASWWVERPEEGELSSGPAQLVGGVGQDGVAELGV
                     RPGGSPVSVELVGPRSHRLRLHSLGPEDEGIYHCAPSAWVQHADYSWYQAGSARSGPV
                     TVYPYTHALDTLFVPLLVGTGVALVTGASILATITCCFMKRLRKR"
     exon            177..554
                     /gene="Igsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            555..1016
                     /gene="Igsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1424
                     /gene="Igsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            1425..1838
                     /gene="Igsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            1839..1969
                     /gene="Igsf8"
                     /inference="alignment:Splign:2.1.0"
     exon            1970..2226
                     /gene="Igsf8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgcaacaaa cgtctgtgca ggatctcagt taatagtcgc cgtaactact tgagtgttta
       61 cagtctctgt tccagctcat accgccccca ggaatctccc cagaatcacc tacgcagaat
      121 gggcgtccct agccccacgc cgctgagttc gctgctgctg ctgctgctaa tacttggagc
      181 caggtgctac gcccggcagg tgcacgtccc caaggggcct ctttaccgtg tggctggcac
      241 cgctgtctct atctcctgca atgtgagtga ctatgagggc ccttcccagc aagacttcga
      301 gtggttcatg tacagacccg aggccccagc tacgtcacta ggcatcatca gcaccaagga
      361 cagccagttc tcctatgctg tctttgggcc tcgagtggca tctggtgacc tgcaggtgca
      421 gcgcctgaag ggggactccg tggtgctcaa gattgctcgc ctgcaggccc aggactctgg
      481 cttttatgag tgctacaccc cctctacgga tactcagtac ctgggcaact acagtgccaa
      541 ggtggagctg agagttcttc cagatgagct gcaggtatct gctgcccctc cagggccccg
      601 aggacgccag gtggcaacct ccccgtcacg cctcacagta catgaggggc aagagctggc
      661 gctgggctgc ctggctcaga ccaaaacgaa gaaacacaca cacctgtcgg tgtcttttgg
      721 gagagccatt cctgaggcgc cagtggggcg agccacccta caggaagtag tgggactgcg
      781 ctctgacatg gctgtggagg ccggagctcc ctatgctgag aggctggttg ccggggagct
      841 tcggctgagc aaggaaggga ctgatcggta ccgcatggtg gttgggggtg cccaggctgg
      901 agactccggc acctaccact gcactgccgc tgagtggatt caagatcctg atggctcctg
      961 ggttcaggtc gcagagaaga gggcagtcct ggctcatgtg gatgtgcaga cactgtccag
     1021 ccagctagca gtgacagtgg gacctggtga acggcggatt ggcccagggg aacccttgga
     1081 actgctgtgt aatgtgtcgg gggcattgcc cccagcaggc cgtcatgctg catactctgt
     1141 gggctgggag atggcccctg caggggctcc agggcctgga cgcctggtgg cccagctgga
     1201 cacagaaggt ataggcagcc tgggccctgg ctatgaagac aggcacattg ccatggagaa
     1261 agtagcatcc agaacctacc gactacggct ggaggctgcc aggcccgctg acgcgggcac
     1321 ctaccgctgc ctcgccaaag cctacgttcg aggctctggg acccggcttc gtgaagcagc
     1381 cagtgctcgt tcccggcctc tcccggtgca tgtgagagaa gaaggcgtgg tgctagaggc
     1441 cgtggcgtgg ctagcagggg gcactgtgta ccggggagag accgcctccc tgctgtgtaa
     1501 catctctgtg cggggcggcc ccccggggct gcgactagca gccagctggt gggtggagag
     1561 accagaggag ggcgaactga gctctggtcc tgctcagctt gtgggtggag tgggtcagga
     1621 cggtgtggca gagctgggag tccggcctgg agggagtcct gtcagtgtgg agctggtggg
     1681 acccagaagt catcggctga gactgcacag cttggggccc gaggacgaag gcatatacca
     1741 ctgtgcgccc agcgcctggg tgcagcacgc tgactatagc tggtaccagg caggcagtgc
     1801 gcgctccggg cccgtcacgg tctaccccta cacgcatgct ctggataccc tgtttgtgcc
     1861 cttgttggtg ggtacaggag tcgccctagt tacgggagcc agcatcctcg ctaccatcac
     1921 ctgctgtttt atgaagaggc tgaggaagcg gtgatctgta gcaccccagt tcttgcaggt
     1981 gtcaactgtc ttccagtcag tgccacccct cctctggttg cctggatacc ctctccctcc
     2041 gtccagccct cctttaattt atttgaccgg tctgtctgtc gccacctggg agcgggagac
     2101 atggctcccc tcttcccacc ttccgtcaag tttcctggtt cttagtttca cactcatgtt
     2161 gtaggaaggc cagttcctgc cctcaaacta gtttttctaa aatgtgaata aactggtttt
     2221 ataaaa
//
