LOCUS       NM_001372112            2361 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus insulin-like growth factor 2 mRNA binding protein
            3 (Igf2bp3), mRNA.
ACCESSION   NM_001372112 XM_003749741 XM_003753893
VERSION     NM_001372112.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2361)
  AUTHORS   Okazaki,Y., Nagai,H., Chew,S.H., Li,J., Funahashi,S., Tsujimura,T.
            and Toyokuni,S.
  TITLE     CD146 and insulin-like growth factor 2 mRNA-binding protein 3
            predict prognosis of asbestos-induced rat mesothelioma
  JOURNAL   Cancer Sci 104 (8), 989-995 (2013)
   PUBMED   23621518
  REMARK    GeneRIF: The overexpression of CD146 and/or IMP3 was proportionally
            correlated with shortened survival.
REFERENCE   2  (bases 1 to 2361)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 2361)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 2361)
  AUTHORS   Chao,J.A., Patskovsky,Y., Patel,V., Levy,M., Almo,S.C. and
            Singer,R.H.
  TITLE     ZBP1 recognition of beta-actin zipcode induces RNA looping
  JOURNAL   Genes Dev 24 (2), 148-158 (2010)
   PUBMED   20080952
REFERENCE   5  (bases 1 to 2361)
  AUTHORS   Nielsen,J., Christiansen,J., Lykke-Andersen,J., Johnsen,A.H.,
            Wewer,U.M. and Nielsen,F.C.
  TITLE     A family of insulin-like growth factor II mRNA-binding proteins
            represses translation in late development
  JOURNAL   Mol Cell Biol 19 (2), 1262-1270 (1999)
   PUBMED   9891060
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1 and AA998402.1.
            
            On or before Aug 14, 2019 this sequence version replaced
            XM_003749741.4, XM_003753893.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY724479.1, SRR26643299.19199.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-416               JAXUCZ010000004.1  79525315-79525730   c
            417-477             JAXUCZ010000004.1  79524293-79524353   c
            478-526             JAXUCZ010000004.1  79477800-79477848   c
            527-578             JAXUCZ010000004.1  79439679-79439730   c
            579-642             JAXUCZ010000004.1  79439529-79439592   c
            643-924             JAXUCZ010000004.1  79423006-79423287   c
            925-1059            JAXUCZ010000004.1  79417176-79417310   c
            1060-1182           JAXUCZ010000004.1  79415543-79415665   c
            1183-1318           JAXUCZ010000004.1  79413651-79413786   c
            1319-1444           JAXUCZ010000004.1  79411824-79411949   c
            1445-1561           JAXUCZ010000004.1  79401372-79401488   c
            1562-1636           JAXUCZ010000004.1  79396935-79397009   c
            1637-1768           JAXUCZ010000004.1  79394507-79394638   c
            1769-1882           JAXUCZ010000004.1  79393880-79393993   c
            1883-2344           JAXUCZ010000004.1  79393067-79393528   c
            2345-2361           AA998402.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..2361
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     gene            1..2361
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /note="insulin-like growth factor 2 mRNA binding protein
                     3"
                     /db_xref="GeneID:312320"
                     /db_xref="RGD:1306512"
     exon            1..416
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     CDS             242..1981
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /note="insulin-like growth factor 2, binding protein 3"
                     /codon_start=1
                     /product="insulin-like growth factor 2 mRNA-binding
                     protein 3"
                     /protein_id="NP_001359041.1"
                     /db_xref="GeneID:312320"
                     /db_xref="RGD:1306512"
                     /translation="MNKLYIGNLSDHAGPADLESVFKDAKIPVAGPFLVKTGYAFVDC
                     PDEGWALKAIEALSGKMELHGKPMEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLV
                     QYGVVESCEQVNTDSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDETAA
                     QQSPSPQLRGRRGPGQRGSSRQTSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATI
                     RNITKQTQSKIDVHRKENTGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEE
                     IPLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVE
                     TCAKAEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSA
                     MTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDAK
                     VRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVKLEAHIRVPSFAAGRVIGKGGK
                     TVNELQNLSSAEVVVPRDQTPDENDQVVVKITGHFYACQVAQRKIQEILTQVKQHQQQ
                     KALQSGAPQSRRK"
     exon            417..477
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     exon            478..526
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     exon            527..578
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     exon            579..642
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     exon            643..924
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1059
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1182
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1318
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..1444
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..1561
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     exon            1562..1636
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..1768
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     exon            1769..1882
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
     exon            1883..2345
                     /gene="Igf2bp3"
                     /gene_synonym="Ab2-255; RGD1306512"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaagactcg acgctgggct cgtcgctagg tttttttctt tctctctctt ttttttaata
       61 cccagaagag gaaaaaggac cctgggatct ggttttcgcc cgccgctccc gtgcttgggt
      121 cactgtgtgt gggtttgaaa ggcgagggga gaagaacaaa atccaccggc tccatcctcc
      181 gccgtgggtg ctttttaatt tagcattttt cctcgggttt taaaacaacc ccctcttcac
      241 aatgaacaaa ttgtacatcg ggaacctcag cgaccacgcc ggccccgcgg acctggaaag
      301 tgtcttcaag gacgctaaga tcccggtggc cggccccttc ctggtgaaga cgggctacgc
      361 gttcgtggac tgcccggacg agggctgggc cctcaaggcc atcgaggcgc tttcaggtaa
      421 aatggaacta catgggaaac cgatggaagt tgagcactcg gtccccaaac ggcagaggat
      481 tcggaaactt cagatacgaa atatcccacc ccacttacaa tgggaggtgc tggatagttt
      541 actagtccag tatggagtgg tggagagctg tgagcaagtg aacacggact cggaaacagc
      601 agttgtaaat gtaacctatt ccagtaagga ccaagctaga caagccttag acaaactgaa
      661 tggattccag ttagagaact tcaccttgaa ggttgcctac atcccagatg aaactgctgc
      721 ccagcaaagc ccctcacctc agctccgagg gcgccggggg ccagggcagc ggggctcatc
      781 caggcagacg tctccaggat ccgtgtccaa gcagaagccc tgtgacctgc cgctgcgcct
      841 gctggtgccc acccagtttg ttggagccat tataggaaaa gaaggtgcca ccattcgcaa
      901 catcaccaaa cagacccagt ctaagatcga tgtccatcgt aaggagaata caggggccgc
      961 ggagaagtcc attactatcc tctctacccc tgaaggcact tctgcagctt gtaagtctat
     1021 tctggagatt atgcataagg aagcgcaaga tataaaattc acagaggaga tccccttgaa
     1081 gattttagct cacaataact ttgtaggccg tctcattggt aaagaaggaa ggaaccttaa
     1141 aaaaattgag caagacacgg acactaaaat cacgatatct ccattgcagg aactgacgtt
     1201 gtacaatccg gagcgtacca ttacagttaa aggcaatgtt gagacgtgtg ccaaggctga
     1261 ggaggaaata atgaagaaga tcagggagtc ctatgaaaat gacattgctt ccatgaatct
     1321 tcaagcacat ttaatccctg gattaaatct gaatgccttg ggtctgttcc cacccacttc
     1381 agggatgcca cctcccacct cagggccccc ttcagccatg actcctccct accctcaatt
     1441 tgagcaatca gagacggaga ccgtgcacct gttcatcccc gccctgtcgg tcggtgccat
     1501 cattggcaag cagggtcaac acatcaaaca gctttctcgt tttgcaggag cttcgattaa
     1561 gatcgcgcca gccgaagcac cagatgctaa agtgaggatg gtgatcatca ctggaccacc
     1621 agaggctcag ttcaaggctc aggggagaat ttatggaaaa attaaagaag aaaactttgt
     1681 gagtcctaag gaagaggtga aacttgaagc tcacatcaga gtgccgtcct ttgctgctgg
     1741 cagagtcatt gggaaaggag gcaaaacggt gaatgaactc cagaatttat caagtgctga
     1801 ggttgttgtc ccccgtgacc agacacctga tgagaatgat caagtcgttg tcaaaataac
     1861 tggccacttc tatgcttgcc aggttgccca gaggaaaatt caggaaattc tgactcaggt
     1921 aaagcagcac caacagcaga aagctctgca gagtggagca cctcagtcaa ggcggaagta
     1981 aaggctcagg agacagccac cacagaggca ggcgccaaac caaagacaga tctgcttaac
     2041 caacagacgg gcgctgaccc acccagaatc acatgcacga gtttttacct agctggttgt
     2101 ttgtgaggac caggcaactc gaactcctgt ctctgtgaga atgtatactt tatgctctct
     2161 gaaatatatg acacccagct ttaaaaaaag aaaaaaagtg ggggtaggga acgagaactc
     2221 tgcacttccc ttgtgatatc agagtataac aaatgtgcta atttttctta atatccttcc
     2281 ataatgccaa aaattggcat aaatggtaca ttcactaaat ttatcaaata aatttaaaac
     2341 taggaaaaaa aaaaaaaaaa a
//
