LOCUS       NM_001107093            2548 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus intraflagellar transport 57 (Ift57), mRNA.
ACCESSION   NM_001107093 XM_001058583 XM_221496
VERSION     NM_001107093.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2548)
  AUTHORS   Karam,A., Tebbe,L., Weber,C., Messaddeq,N., Morle,L., Kessler,P.,
            Wolfrum,U. and Trottier,Y.
  TITLE     A novel function of Huntingtin in the cilium and retinal ciliopathy
            in Huntington's disease mice
  JOURNAL   Neurobiol Dis 80, 15-28 (2015)
   PUBMED   25989602
REFERENCE   2  (bases 1 to 2548)
  AUTHORS   Liew,G.M., Ye,F., Nager,A.R., Murphy,J.P., Lee,J.S., Aguiar,M.,
            Breslow,D.K., Gygi,S.P. and Nachury,M.V.
  TITLE     The intraflagellar transport protein IFT27 promotes BBSome exit
            from cilia through the GTPase ARL6/BBS3
  JOURNAL   Dev Cell 31 (3), 265-278 (2014)
   PUBMED   25443296
REFERENCE   3  (bases 1 to 2548)
  AUTHORS   Ishikawa,H., Ide,T., Yagi,T., Jiang,X., Hirono,M., Sasaki,H.,
            Yanagisawa,H., Wemmer,K.A., Stainier,D.Y., Qin,H., Kamiya,R. and
            Marshall,W.F.
  TITLE     TTC26/DYF13 is an intraflagellar transport protein required for
            transport of motility-related proteins into flagella
  JOURNAL   Elife 3, e01566 (2014)
   PUBMED   24596149
  REMARK    Erratum:[Elife. 2014 Apr 01;3:e02897. PMID: 24692455]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2548)
  AUTHORS   Wang,C., Low,W.C., Liu,A. and Wang,B.
  TITLE     Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting
            cytoplasmic retention of transcription factor GLI3 and affecting
            ciliogenesis
  JOURNAL   J Biol Chem 288 (41), 29518-29529 (2013)
   PUBMED   23955340
REFERENCE   5  (bases 1 to 2548)
  AUTHORS   Howard,P.W., Jue,S.F. and Maurer,R.A.
  TITLE     Interaction of mouse TTC30/DYF-1 with multiple intraflagellar
            transport complex B proteins and KIF17
  JOURNAL   Exp Cell Res 319 (14), 2275-2281 (2013)
   PUBMED   23810713
REFERENCE   6  (bases 1 to 2548)
  AUTHORS   Follit,J.A., Xu,F., Keady,B.T. and Pazour,G.J.
  TITLE     Characterization of mouse IFT complex B
  JOURNAL   Cell Motil Cytoskeleton 66 (8), 457-468 (2009)
   PUBMED   19253336
REFERENCE   7  (bases 1 to 2548)
  AUTHORS   Luby-Phelps,K., Fogerty,J., Baker,S.A., Pazour,G.J. and
            Besharse,J.C.
  TITLE     Spatial distribution of intraflagellar transport proteins in
            vertebrate photoreceptors
  JOURNAL   Vision Res 48 (3), 413-423 (2008)
   PUBMED   17931679
REFERENCE   8  (bases 1 to 2548)
  AUTHORS   Houde,C., Dickinson,R.J., Houtzager,V.M., Cullum,R., Montpetit,R.,
            Metzler,M., Simpson,E.M., Roy,S., Hayden,M.R., Hoodless,P.A. and
            Nicholson,D.W.
  TITLE     Hippi is essential for node cilia assembly and Sonic hedgehog
            signaling
  JOURNAL   Dev Biol 300 (2), 523-533 (2006)
   PUBMED   17027958
REFERENCE   9  (bases 1 to 2548)
  AUTHORS   Baker,S.A., Freeman,K., Luby-Phelps,K., Pazour,G.J. and
            Besharse,J.C.
  TITLE     IFT20 links kinesin II with a mammalian intraflagellar transport
            complex that is conserved in motile flagella and sensory cilia
  JOURNAL   J Biol Chem 278 (36), 34211-34218 (2003)
   PUBMED   12821668
REFERENCE   10 (bases 1 to 2548)
  AUTHORS   Gervais,F.G., Singaraja,R., Xanthoudakis,S., Gutekunst,C.A.,
            Leavitt,B.R., Metzler,M., Hackam,A.S., Tam,J., Vaillancourt,J.P.,
            Houtzager,V., Rasper,D.M., Roy,S., Hayden,M.R. and Nicholson,D.W.
  TITLE     Recruitment and activation of caspase-8 by the
            Huntingtin-interacting protein Hip-1 and a novel partner Hippi
  JOURNAL   Nat Cell Biol 4 (2), 95-105 (2002)
   PUBMED   11788820
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473967.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_221496.4, XM_001058583.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760434 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2548
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     gene            1..2548
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /note="intraflagellar transport 57"
                     /db_xref="GeneID:303968"
                     /db_xref="RGD:1305947"
     exon            1..256
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..1334
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /note="estrogen-related receptor beta like 1;
                     intraflagellar transport 57 homolog"
                     /codon_start=1
                     /product="intraflagellar transport protein 57 homolog"
                     /protein_id="NP_001100563.1"
                     /db_xref="GeneID:303968"
                     /db_xref="RGD:1305947"
                     /translation="MAAAAAVIPPSGLDDGVSRARGEGAGEAVVERGPGAAYHMFVVM
                     EDLVEKLKLLRYEEELLRKSNLKPPSRHYFALPTNPGEQFYMFCTLAAWLINKTGRAF
                     EQPQEYDDPNATISNILSELRSFGRTADFPPSKLKSGYGEHVCYVLDCLAEEALKYIG
                     FTWKRPSYPVEELEEETVPEDDAELTLSKVDEEFVEEETDNEENFIDLNVLKAQTYRL
                     DTNESAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHKSGIE
                     SALKETKGFLDKLHNEISRTLEKIGSREKYINNQLEHLVQEYRGAQAQLSEARERYQQ
                     GNGGVTERTRLLSEVTEELEKVKQEMEEKGSSMTDGTPLVKIKQSLTKLKQETVQMDI
                     RIGVVEHTLLQSKLKEKCNMTRDMHAAVTPESAIGFY"
     exon            257..419
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            420..538
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            539..629
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            630..698
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            699..821
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            822..893
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            894..1025
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1088
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1155
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..2548
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gatcctagcc cgggtccagc ccggccctgt ggatctgagc agcgatggct gccgcggccg
       61 cggtgatccc gccgtcgggc ttggacgatg gggtgtctcg ggctcgcggg gaaggcgctg
      121 gggaggcggt ggtggagcgc gggccgggag cggcctacca catgttcgtg gtgatggaag
      181 acttagtgga gaagctgaag ctgctccgct acgaggagga gctactccga aagagcaatc
      241 tgaagccccc gtccagacac tactttgctc tgcctaccaa tcccggtgag cagttctaca
      301 tgttttgcac tcttgctgcc tggctgatca acaagactgg ccgtgccttt gagcagcctc
      361 aggaatatga cgatcccaat gcaactatat ctaacatcct gtctgagctc cgctcttttg
      421 ggagaactgc agattttcct ccttcaaaat taaagtctgg ttatggagaa catgtatgct
      481 atgttcttga ttgtttagct gaagaagcat taaaatatat tggtttcact tggaaaaggc
      541 catcataccc agtggaagag ttagaagaag aaactgttcc ggaagatgat gcggagttaa
      601 cattaagtaa agtggatgaa gagtttgtgg aagaggagac agataatgaa gaaaacttta
      661 ttgatctcaa cgttttaaag gcccagacct atcgcttgga cacaaacgag tctgccaaac
      721 aagaagatat tttggaatct acgacagatg ctgcggaatg gagtctagaa gtggaacgtg
      781 tactacccca gctgaaagtc acgatcagga ctgacaacaa ggattggaga atccacgttg
      841 accaaatgca ccagcacaaa agtggaattg aatctgctct aaaggagacc aaggggttct
      901 tggacaagct ccataatgaa attagcagga ctctggaaaa gatcggcagc cgggaaaagt
      961 acattaacaa tcaacttgag cacttggttc aagaatatcg tggggcccag gcccagctaa
     1021 gtgaggcaag ggaacgctac cagcagggca atggcggagt aactgaacgg accagactcc
     1081 tgtctgaggt gacagaagaa ttagaaaagg taaaacaaga aatggaagag aagggcagca
     1141 gcatgacgga tggcactcct ttggtgaaga ttaagcagag cttaaccaag ctgaagcaag
     1201 aaactgttca gatggacatt agaatcgggg ttgtggagca cacgctgctt cagtcaaagc
     1261 tcaaggagaa gtgtaacatg accagagaca tgcatgcggc tgtcacccca gagtcagcaa
     1321 tcggcttcta ttaaacacat ggtgttcctg cgtctgatga tttgtttttt atatcaaatg
     1381 atttttttaa tgttgcatgg atttccaaac agtttatact tcttcaagca tatccagtgg
     1441 gtatttttgc acatgttcta tcatggtgac tatgatggct aaagccttta caatgaatat
     1501 agtatttaat aaagtactta aaattatcct gttcagagaa gctttcactg gcattgccaa
     1561 tggcctactg ctgcctggtg gttcattcct tatgagaatg acccttgtgt catgtgtatc
     1621 ccatggcact ctggacgacc gacagaagac tggtacgtct ggtgatgccc agagctggtg
     1681 ccattctgta atgaccacta gtacttacgt attagaggag ctgagaatag gtgttagagt
     1741 tcatcggaag ccaaatttcc cttgcctcat ctctacagtt acatgatatt actacctcct
     1801 taactataaa aataaaaagt ccagcatcca tgttaacaag tgaaacctag tattgaaata
     1861 gtagttcagc catatttggt tcagctgcta taatgaggaa agatgcctga gcctgtatct
     1921 gcatcccacc cgttcacacg aagtcagcca tgctaagcac agtcaggtag aagccaccat
     1981 aatgagtctc atggttgtcg actagcatga cattcttttc ttaggcaccc tactcagcag
     2041 tttttctaga ctaggatttc taaatcagcc ataagcatta ttgaagagta gcttttctgg
     2101 gctatggctc agttcttgtg tagcagattt gatcttcagc actgtataaa ccagtcggta
     2161 atgcacacct ataatgtaga ctcatggtga ggcaggagag tctgaagttc aaactcatgg
     2221 acctgcacga tggctcagtg gggaaaggct cttgctacta agcctgatat ctagagtttt
     2281 atgcccaggt cctaaagttt gtccacaggt gtgtacacct agatgtgtac aaacatagac
     2341 acacacacaa tagatagata gatagataga tagatagata gatagataga tagatagata
     2401 gatagataat agacagatac ctttcattag ctttaagaaa taaaagcact tcatagtaaa
     2461 ttttgactta aaaatgctta tgtttatttt atacttagga acaacattaa ttaattttta
     2521 atataacaac aatattaatt tttaatcc
//
