LOCUS       NP_001100563             429 aa            linear   ROD 03-APR-2024
DEFINITION  intraflagellar transport protein 57 homolog [Rattus norvegicus].
ACCESSION   NP_001100563 XP_001058583 XP_221496
VERSION     NP_001100563.1
DBSOURCE    REFSEQ: accession NM_001107093.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 429)
  AUTHORS   Karam,A., Tebbe,L., Weber,C., Messaddeq,N., Morle,L., Kessler,P.,
            Wolfrum,U. and Trottier,Y.
  TITLE     A novel function of Huntingtin in the cilium and retinal ciliopathy
            in Huntington's disease mice
  JOURNAL   Neurobiol Dis 80, 15-28 (2015)
   PUBMED   25989602
REFERENCE   2  (residues 1 to 429)
  AUTHORS   Liew,G.M., Ye,F., Nager,A.R., Murphy,J.P., Lee,J.S., Aguiar,M.,
            Breslow,D.K., Gygi,S.P. and Nachury,M.V.
  TITLE     The intraflagellar transport protein IFT27 promotes BBSome exit
            from cilia through the GTPase ARL6/BBS3
  JOURNAL   Dev Cell 31 (3), 265-278 (2014)
   PUBMED   25443296
REFERENCE   3  (residues 1 to 429)
  AUTHORS   Ishikawa,H., Ide,T., Yagi,T., Jiang,X., Hirono,M., Sasaki,H.,
            Yanagisawa,H., Wemmer,K.A., Stainier,D.Y., Qin,H., Kamiya,R. and
            Marshall,W.F.
  TITLE     TTC26/DYF13 is an intraflagellar transport protein required for
            transport of motility-related proteins into flagella
  JOURNAL   Elife 3, e01566 (2014)
   PUBMED   24596149
  REMARK    Erratum:[Elife. 2014 Apr 01;3:e02897. PMID: 24692455]
            Publication Status: Online-Only
REFERENCE   4  (residues 1 to 429)
  AUTHORS   Wang,C., Low,W.C., Liu,A. and Wang,B.
  TITLE     Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting
            cytoplasmic retention of transcription factor GLI3 and affecting
            ciliogenesis
  JOURNAL   J Biol Chem 288 (41), 29518-29529 (2013)
   PUBMED   23955340
REFERENCE   5  (residues 1 to 429)
  AUTHORS   Howard,P.W., Jue,S.F. and Maurer,R.A.
  TITLE     Interaction of mouse TTC30/DYF-1 with multiple intraflagellar
            transport complex B proteins and KIF17
  JOURNAL   Exp Cell Res 319 (14), 2275-2281 (2013)
   PUBMED   23810713
REFERENCE   6  (residues 1 to 429)
  AUTHORS   Follit,J.A., Xu,F., Keady,B.T. and Pazour,G.J.
  TITLE     Characterization of mouse IFT complex B
  JOURNAL   Cell Motil Cytoskeleton 66 (8), 457-468 (2009)
   PUBMED   19253336
REFERENCE   7  (residues 1 to 429)
  AUTHORS   Luby-Phelps,K., Fogerty,J., Baker,S.A., Pazour,G.J. and
            Besharse,J.C.
  TITLE     Spatial distribution of intraflagellar transport proteins in
            vertebrate photoreceptors
  JOURNAL   Vision Res 48 (3), 413-423 (2008)
   PUBMED   17931679
REFERENCE   8  (residues 1 to 429)
  AUTHORS   Houde,C., Dickinson,R.J., Houtzager,V.M., Cullum,R., Montpetit,R.,
            Metzler,M., Simpson,E.M., Roy,S., Hayden,M.R., Hoodless,P.A. and
            Nicholson,D.W.
  TITLE     Hippi is essential for node cilia assembly and Sonic hedgehog
            signaling
  JOURNAL   Dev Biol 300 (2), 523-533 (2006)
   PUBMED   17027958
REFERENCE   9  (residues 1 to 429)
  AUTHORS   Baker,S.A., Freeman,K., Luby-Phelps,K., Pazour,G.J. and
            Besharse,J.C.
  TITLE     IFT20 links kinesin II with a mammalian intraflagellar transport
            complex that is conserved in motile flagella and sensory cilia
  JOURNAL   J Biol Chem 278 (36), 34211-34218 (2003)
   PUBMED   12821668
REFERENCE   10 (residues 1 to 429)
  AUTHORS   Gervais,F.G., Singaraja,R., Xanthoudakis,S., Gutekunst,C.A.,
            Leavitt,B.R., Metzler,M., Hackam,A.S., Tam,J., Vaillancourt,J.P.,
            Houtzager,V., Rasper,D.M., Roy,S., Hayden,M.R. and Nicholson,D.W.
  TITLE     Recruitment and activation of caspase-8 by the
            Huntingtin-interacting protein Hip-1 and a novel partner Hippi
  JOURNAL   Nat Cell Biol 4 (2), 95-105 (2002)
   PUBMED   11788820
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473967.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_221496.3, XP_001058583.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760434 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     Protein         1..429
                     /product="intraflagellar transport protein 57 homolog"
                     /note="estrogen-related receptor beta like 1;
                     intraflagellar transport 57 homolog"
                     /calculated_mol_wt=48650
     Region          44..401
                     /region_name="IFT57"
                     /note="Intra-flagellar transport protein 57; pfam10498"
                     /db_xref="CDD:463118"
     CDS             1..429
                     /gene="Ift57"
                     /gene_synonym="Esrrbl1"
                     /coded_by="NM_001107093.1:45..1334"
                     /db_xref="GeneID:303968"
                     /db_xref="RGD:1305947"
ORIGIN      
        1 maaaaavipp sglddgvsra rgegageavv ergpgaayhm fvvmedlvek lkllryeeel
       61 lrksnlkpps rhyfalptnp geqfymfctl aawlinktgr afeqpqeydd pnatisnils
      121 elrsfgrtad fppsklksgy gehvcyvldc laeealkyig ftwkrpsypv eeleeetvpe
      181 ddaeltlskv deefveeetd neenfidlnv lkaqtyrldt nesakqedil esttdaaews
      241 levervlpql kvtirtdnkd wrihvdqmhq hksgiesalk etkgfldklh neisrtleki
      301 gsrekyinnq lehlvqeyrg aqaqlseare ryqqgnggvt ertrllsevt eelekvkqem
      361 eekgssmtdg tplvkikqsl tklkqetvqm dirigvveht llqsklkekc nmtrdmhaav
      421 tpesaigfy
//
