LOCUS       NM_001025045            3921 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Rattus norvegicus intraflagellar transport 56 (Ift56), mRNA.
ACCESSION   NM_001025045 XM_575437
VERSION     NM_001025045.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3921)
  AUTHORS   Xin,D., Christopher,K.J., Zeng,L., Kong,Y. and Weatherbee,S.D.
  TITLE     IFT56 regulates vertebrate developmental patterning by maintaining
            IFTB complex integrity and ciliary microtubule architecture
  JOURNAL   Development 144 (8), 1544-1553 (2017)
   PUBMED   28264835
REFERENCE   2  (bases 1 to 3921)
  AUTHORS   Swiderski,R.E., Nakano,Y., Mullins,R.F., Seo,S. and Banfi,B.
  TITLE     A mutation in the mouse ttc26 gene leads to impaired hedgehog
            signaling
  JOURNAL   PLoS Genet 10 (10), e1004689 (2014)
   PUBMED   25340710
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3921)
  AUTHORS   Ishikawa,H., Ide,T., Yagi,T., Jiang,X., Hirono,M., Sasaki,H.,
            Yanagisawa,H., Wemmer,K.A., Stainier,D.Y., Qin,H., Kamiya,R. and
            Marshall,W.F.
  TITLE     TTC26/DYF13 is an intraflagellar transport protein required for
            transport of motility-related proteins into flagella
  JOURNAL   Elife 3, e01566 (2014)
   PUBMED   24596149
  REMARK    Erratum:[Elife. 2014 Apr 01;3:e02897. doi: 10.7554/eLife.02897..
            PMID: 24692455]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3921)
  AUTHORS   Zhang,Q., Liu,Q., Austin,C., Drummond,I. and Pierce,E.A.
  TITLE     Knockdown of ttc26 disrupts ciliogenesis of the photoreceptor cells
            and the pronephros in zebrafish
  JOURNAL   Mol Biol Cell 23 (16), 3069-3078 (2012)
   PUBMED   22718903
REFERENCE   5  (bases 1 to 3921)
  AUTHORS   Follit,J.A., Xu,F., Keady,B.T. and Pazour,G.J.
  TITLE     Characterization of mouse IFT complex B
  JOURNAL   Cell Motil Cytoskeleton 66 (8), 457-468 (2009)
   PUBMED   19253336
REFERENCE   6  (bases 1 to 3921)
  AUTHORS   Schumacher,J.M., Artzt,K. and Braun,R.E.
  TITLE     Spermatid perinuclear ribonucleic acid-binding protein binds
            microtubules in vitro and associates with abnormal manchettes in
            vivo in mice
  JOURNAL   Biol Reprod 59 (1), 69-76 (1998)
   PUBMED   9674995
REFERENCE   7  (bases 1 to 3921)
  AUTHORS   Bryan,J.H.
  TITLE     Spermatogenesis revisited. V. Spermiogenesis in mice homozygous for
            two different male-sterile mutations (ps and hpy)
  JOURNAL   Cell Tissue Res 221 (1), 169-180 (1981)
   PUBMED   7317942
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Mar 18, 2021 this sequence version replaced NM_001025045.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085935.1, SRR26643287.10752.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               JAXUCZ010000004.1  68057580-68057687
            109-246             JAXUCZ010000004.1  68058144-68058281
            247-339             JAXUCZ010000004.1  68061359-68061451
            340-454             JAXUCZ010000004.1  68063248-68063362
            455-504             JAXUCZ010000004.1  68065261-68065310
            505-650             JAXUCZ010000004.1  68073324-68073469
            651-822             JAXUCZ010000004.1  68076654-68076825
            823-897             JAXUCZ010000004.1  68085749-68085823
            898-1000            JAXUCZ010000004.1  68088309-68088411
            1001-1056           JAXUCZ010000004.1  68090551-68090606
            1057-1110           JAXUCZ010000004.1  68091701-68091754
            1111-1174           JAXUCZ010000004.1  68093223-68093286
            1175-1263           JAXUCZ010000004.1  68097430-68097518
            1264-1347           JAXUCZ010000004.1  68098741-68098824
            1348-1417           JAXUCZ010000004.1  68099725-68099794
            1418-1524           JAXUCZ010000004.1  68109823-68109929
            1525-1658           JAXUCZ010000004.1  68111569-68111702
            1659-3921           JAXUCZ010000004.1  68113230-68115492
FEATURES             Location/Qualifiers
     source          1..3921
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q23"
     gene            1..3921
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /note="intraflagellar transport 56"
                     /db_xref="GeneID:500086"
                     /db_xref="RGD:1561363"
     exon            1..108
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..1770
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /note="tetratricopeptide repeat protein 26; TPR repeat
                     protein 26; tetratricopeptide repeat domain 26"
                     /codon_start=1
                     /product="intraflagellar transport protein 56"
                     /protein_id="NP_001020216.1"
                     /db_xref="GeneID:500086"
                     /db_xref="RGD:1561363"
                     /translation="MMLSRAKPAVGGESPHTDKRKKKGRKIPKLEDLLSQRDFTGAIT
                     LLEFKRHVGEQEEDTNLWIGYCAFHLGDYKRALEEYENAAKEENCNPEVWVNLACTYF
                     FLGMYKQAEAAGFKAPKSRLQNRLLFHLAHKFNDEKKLMNFHQNLQDIKEDQLSLASI
                     HYMRSHYQEAIDIYKRILLDNREYLALNVYVALCYYKLDYYDVSQEVLAVYLQQIPDS
                     TIALNLKACNHFRLYNGKAAEAELKSLMDNASSPFEFAKELIRHNLVVFRGGEGALQV
                     LPPLVDVIPEARLNLVIYYLRQDDVQEAYNLIKDLEPTTPQEYILKGVVNAALGQEMG
                     SRDHMKIAQQFFQLVGGSASECDTIPGRQCMASCFFLLKQFDDVLIYLNSFKSYFYND
                     DIFNFNYAQAKAATGNTSEGEEVFLLIQSEKLKNDYIYLSWLARCYIMNKKPRLAWEL
                     YLKMETSGESFSLLQLIANDCYKMGQFYYSAKAFDVLERLDPNPEYWEGKRGACVGIF
                     QMILAGREPKETLREVLHLLRSTGNTQVEYIIRIMKKWAKENRVPI"
     exon            109..246
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            247..339
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            340..454
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            455..504
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            505..650
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            651..822
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            823..897
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            898..1000
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1056
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1110
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1174
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            1175..1263
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..1347
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            1348..1417
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            1418..1524
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            1525..1658
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
     exon            1659..3921
                     /gene="Ift56"
                     /gene_synonym="Ttc26"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggcgttgcc gtggagacgg agctctctgt gtggatgtgg caactcgccg aagcacagct
       61 tttgcagact atcttcagcc gggggctcac aggaccaacg ccaagatgat gctttcaagg
      121 gccaaacccg ctgtgggtgg ggagtcacca cacactgaca aaagaaagaa gaaagggagg
      181 aagattccaa aactagagga tctactttcg caaagagatt tcactggcgc tattacccta
      241 ttggagttca aacgccatgt tggggagcaa gaagaggaca ctaacttatg gattggctac
      301 tgtgcttttc acctgggtga ctacaagaga gctttggagg aatacgaaaa cgcggcgaag
      361 gaggagaatt gcaacccgga agtgtgggta aacttggcct gcacctactt tttccttgga
      421 atgtataaac aagcagaagc tgctgggttt aaagctccaa aaagccgact ccaaaaccgc
      481 ctactattcc atctggctca caagtttaat gatgagaaga aattaatgaa ctttcatcag
      541 aatcttcagg atatcaaaga agaccagctt agcttggcct caatccacta catgcgatct
      601 cattaccaag aagctattga tatatacaag cggatactgc tggataacag ggaatacctg
      661 gccctcaatg tgtatgtggc cctctgctac tacaaattgg attactatga tgtgtctcaa
      721 gaagtcctgg ctgtttacct tcagcaaatt cctgatagca ccatcgccct caaccttaag
      781 gcctgcaatc actttcgcct ttataatggc aaagcagctg aggcagagct caaaagcttg
      841 atggacaatg cctcttcacc atttgaattt gctaaagaac tcatcagaca caatctggtt
      901 gttttccgag gaggagaagg ggctttgcag gttttacctc ccctagttga tgtcattcct
      961 gaagctaggc taaacctagt gatttactac cttcgtcaag atgatgtgca ggaagcctat
     1021 aatttgatca aggacctgga acctactaca cctcaggagt atattctcaa gggagttgtc
     1081 aatgcagccc ttggccagga aatgggttca agggatcata tgaaaattgc ccaacagttt
     1141 ttccagttgg taggaggatc agctagtgaa tgtgatacaa taccaggaag gcagtgcatg
     1201 gcttcctgtt tcttcctgct taaacaattt gatgatgtct tgatttacct caactctttt
     1261 aagagttact tctacaacga cgacatcttt aactttaatt atgcccaagc caaagctgca
     1321 acaggcaaca ccagtgaggg tgaggaggtt ttcctcttga tccaaagtga gaaattgaaa
     1381 aatgattaca tttaccttag ttggttagct cgctgctata ttatgaacaa gaaaccaaga
     1441 ctagcttggg aactttatct caagatggaa acctccggcg agtccttcag cctcttacag
     1501 ctcattgcca atgactgtta caagatgggc cagttctact attcagccaa ggcttttgat
     1561 gtcctagaga ggctggatcc caaccctgaa tactgggaag gcaagagggg tgcctgtgtg
     1621 ggaattttcc agatgatttt agctgggaga gaacccaaag agaccctccg agaagtgctg
     1681 catttgctga gaagcacagg aaacacccaa gtggagtata tcatcaggat catgaagaag
     1741 tgggccaagg agaatagagt gcccatctaa gcagccgggc tttaggccag gaccagcttc
     1801 ctctcacatc aaattggaac tgttttcctg cacttgaata tgcgatccag gaccctgttt
     1861 gattgacatt tccttccttg ctcttcgagc gttaggatga gcgggtggtt atgtgtggac
     1921 ttagccatca ggcagcacaa atctccctgg tctgtgctga cacctaatgt aatctactgg
     1981 tgaaagtact ttgggcttcc ctggtgcctt tcttccagaa tcattccgaa tactcttaca
     2041 taacttactg gcttttagga ataggtaata gttttgtttt tctttctgtt acatttcagg
     2101 acattttctt ctagctgcag tgacaagtac ctttatacta aagaattgcc atcatttgat
     2161 catcttgtgc attagcccat ccatgaatac atttctgagt cctgagggaa gtctttcgag
     2221 ctatgtgatt ctcaggatgg ccatgaggcc ctctagtgaa aggctgtcag tagtagatag
     2281 ttggcgtatg ggaccactgc cttagtgagt aaagcgctgc ttgtgtagtt tgttacagcg
     2341 agacaagtgg agtatgtgcg tttttaaaac atgaatgaaa ggaagaactt ggcatctctg
     2401 aaggtacgca aagccagggc caggttctta atatctgctt aatggacagc agctttgaac
     2461 atacgactgg gaaagttttc atgaaacata tatacgtaac tttttttttt ctgagacagg
     2521 gtttctccat gtagccctgg ctgtcctgga actcactctg tagaccaggc tggccttgaa
     2581 ctcagacatc cgcctgcctc tgccttccga gtgctgggat caaaggcgtg ctcaccactg
     2641 ctcagcacat gtacatgttt gtattgcaca cacacgagca tggtgtaggg atttattgat
     2701 acaattataa accagggtcc tttgaagaga ccgctctatc gcatctcagc ctcgtgtctc
     2761 tgagctgtcg tcacataaac ttctttcaac aaactattgt caggtttata tcccactttc
     2821 agaaaacaga cccacatctc tttgtgtttc agataacctg tttatatgct ctataatttt
     2881 cttctgtaag tctgagaccc atcctcgtag agcaaagact gcacaaagga agaagtggag
     2941 gagtttttag aaacactagt tcttcctcct gccccagccc ccagctgcag atggcactct
     3001 gcacagacag ggaaacctgt acagggtgaa acagctgaag caataggacc tgctggacgc
     3061 agcttctcgc tgaccaatgc caaggcgggc tccagctctg cctagaggat ggccagtgtg
     3121 ccatctttta cattaggctc agatatgatt ggtccaaaac acaaatcaca atacaggtct
     3181 gacaggactg caggaaacaa agatgcacca tgtctttatg ccagagcttc tcctagtctt
     3241 gttctggtat tcccactctt tcaatagaac ctggttctct ttgtcaaagg tactaggtgg
     3301 atcagatgac ccaacctgct ttatagttct gtggatcctt cttaggaaac ttacttttgc
     3361 tttaaatact tgtaagccga agagtgggaa ggcagatgaa gtcccaggag ttggcatctt
     3421 ccagtgaagc gctgttcagt tccagctcct cattcctgaa agacactcat tcacactgat
     3481 gtacttacca atgagaattt ttcagtttac aactcagtag tctctatgac attttccttg
     3541 acagaaggat gtctgttccc aacagcagaa ttttagatta ctctttaaag ttttttaatc
     3601 tacaggattg aaacgaaaaa tatgaaggaa agttgaagag aagcacatgc agttctgtta
     3661 ggagggataa ttgtttctga ttgtcttgac agggtgtcaa ggttcggagc tgttttctct
     3721 acagatgaca gcccagagaa gaagggcccc aggctgggaa tgtgtaattt atacagtcta
     3781 tagtatcaat gtactattta aaaataatct gcaggttata cttacaaatg gaaaaacact
     3841 tttacagtta ttttttatat gacaaaagaa tcacatacca ctgtcctata tttaaattaa
     3901 aatttatttt ttggttcttt t
//
