LOCUS       NM_001308389            2083 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus intraflagellar transport 52 (Ift52), mRNA.
ACCESSION   NM_001308389
VERSION     NM_001308389.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2083)
  AUTHORS   Dharmat,R., Eblimit,A., Robichaux,M.A., Zhang,Z., Nguyen,T.T.,
            Jung,S.Y., He,F., Jain,A., Li,Y., Qin,J., Overbeek,P., Roepman,R.,
            Mardon,G., Wensel,T.G. and Chen,R.
  TITLE     SPATA7 maintains a novel photoreceptor-specific zone in the distal
            connecting cilium
  JOURNAL   J Cell Biol 217 (8), 2851-2865 (2018)
   PUBMED   29899041
REFERENCE   2  (bases 1 to 2083)
  AUTHORS   Zhang,W., Taylor,S.P., Nevarez,L., Lachman,R.S., Nickerson,D.A.,
            Bamshad,M., Krakow,D. and Cohn,D.H.
  CONSRTM   University of Washington Center for Mendelian Genomics Consortium
  TITLE     IFT52 mutations destabilize anterograde complex assembly, disrupt
            ciliogenesis and result in short rib polydactyly syndrome
  JOURNAL   Hum Mol Genet 25 (18), 4012-4020 (2016)
   PUBMED   27466190
REFERENCE   3  (bases 1 to 2083)
  AUTHORS   Liew,G.M., Ye,F., Nager,A.R., Murphy,J.P., Lee,J.S., Aguiar,M.,
            Breslow,D.K., Gygi,S.P. and Nachury,M.V.
  TITLE     The intraflagellar transport protein IFT27 promotes BBSome exit
            from cilia through the GTPase ARL6/BBS3
  JOURNAL   Dev Cell 31 (3), 265-278 (2014)
   PUBMED   25443296
REFERENCE   4  (bases 1 to 2083)
  AUTHORS   Ye,X., Zeng,H., Ning,G., Reiter,J.F. and Liu,A.
  TITLE     C2cd3 is critical for centriolar distal appendage assembly and
            ciliary vesicle docking in mammals
  JOURNAL   Proc Natl Acad Sci U S A 111 (6), 2164-2169 (2014)
   PUBMED   24469809
REFERENCE   5  (bases 1 to 2083)
  AUTHORS   Ishikawa,H., Ide,T., Yagi,T., Jiang,X., Hirono,M., Sasaki,H.,
            Yanagisawa,H., Wemmer,K.A., Stainier,D.Y., Qin,H., Kamiya,R. and
            Marshall,W.F.
  TITLE     TTC26/DYF13 is an intraflagellar transport protein required for
            transport of motility-related proteins into flagella
  JOURNAL   Elife 3, e01566 (2014)
   PUBMED   24596149
  REMARK    Erratum:[Elife. 2014 Apr 01;3:e02897. PMID: 24692455]
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2083)
  AUTHORS   Sedmak,T. and Wolfrum,U.
  TITLE     Intraflagellar transport molecules in ciliary and nonciliary cells
            of the retina
  JOURNAL   J Cell Biol 189 (1), 171-186 (2010)
   PUBMED   20368623
REFERENCE   7  (bases 1 to 2083)
  AUTHORS   Follit,J.A., Xu,F., Keady,B.T. and Pazour,G.J.
  TITLE     Characterization of mouse IFT complex B
  JOURNAL   Cell Motil Cytoskeleton 66 (8), 457-468 (2009)
   PUBMED   19253336
REFERENCE   8  (bases 1 to 2083)
  AUTHORS   Follit,J.A., Tuft,R.A., Fogarty,K.E. and Pazour,G.J.
  TITLE     The intraflagellar transport protein IFT20 is associated with the
            Golgi complex and is required for cilia assembly
  JOURNAL   Mol Biol Cell 17 (9), 3781-3792 (2006)
   PUBMED   16775004
REFERENCE   9  (bases 1 to 2083)
  AUTHORS   Liu,A., Wang,B. and Niswander,L.A.
  TITLE     Mouse intraflagellar transport proteins regulate both the activator
            and repressor functions of Gli transcription factors
  JOURNAL   Development 132 (13), 3103-3111 (2005)
   PUBMED   15930098
REFERENCE   10 (bases 1 to 2083)
  AUTHORS   Baker,S.A., Freeman,K., Luby-Phelps,K., Pazour,G.J. and
            Besharse,J.C.
  TITLE     IFT20 links kinesin II with a mammalian intraflagellar transport
            complex that is conserved in motile flagella and sensory cilia
  JOURNAL   J Biol Chem 278 (36), 34211-34218 (2003)
   PUBMED   12821668
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1 and BC162007.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.20024.1,
                                           SRR26643284.5127.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                JAXUCZ010000003.1  172092025-172092077
            54-178              JAXUCZ010000003.1  172095349-172095473
            179-266             JAXUCZ010000003.1  172096241-172096328
            267-396             JAXUCZ010000003.1  172096533-172096662
            397-472             JAXUCZ010000003.1  172097206-172097281
            473-544             JAXUCZ010000003.1  172099170-172099241
            545-671             JAXUCZ010000003.1  172100826-172100952
            672-761             JAXUCZ010000003.1  172102399-172102488
            762-830             JAXUCZ010000003.1  172104841-172104909
            831-985             JAXUCZ010000003.1  172107616-172107770
            986-1073            BC162007.1         986-1073
            1074-1182           JAXUCZ010000003.1  172113179-172113287
            1183-2083           JAXUCZ010000003.1  172115592-172116492
FEATURES             Location/Qualifiers
     source          1..2083
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..2083
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /note="intraflagellar transport 52"
                     /db_xref="GeneID:362265"
                     /db_xref="RGD:1311004"
     exon            1..53
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /inference="alignment:Splign:2.1.0"
     exon            54..178
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /inference="alignment:Splign:2.1.0"
     CDS             60..1340
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /note="intraflagellar transport 52 homolog"
                     /codon_start=1
                     /product="intraflagellar transport protein 52 homolog"
                     /protein_id="NP_001295318.1"
                     /db_xref="GeneID:362265"
                     /db_xref="RGD:1311004"
                     /translation="MEKELRSTILFNAYKKEVFTTNTGYKSLQKRLRSNWKIQSLKDE
                     ITSEKLIGVKLWITAGPREKFTAAEFEVLKKYLDSGGDILVMLGEGGESRFDTNINFL
                     LEEYGIMVNNDAVVRNVYYKYFHPKEALVSDGVLNREISRAAGKAVPGVIDEENSGNN
                     AQALTFVYPYGATLSVMKPAVAVLSTGSVCFPLNRPILAFYHSKNQGFGKLAVLGSCH
                     MFSDQYLDKEENSKIMDVVFQWLTTGDIHLNQIDAEDPEISDYTMVPDTATLSEQLRV
                     CLQEGDENPRDFTTLFDLSIYQLDTTCLPKVIKAHEELNVKHEPLQLVQPQFEMPLPA
                     LQPAVFPPSFRELPPPPLELFDLDETFSSEKARLAQITNKCTDEDLEFYVRKCGDILG
                     VTSKLPKDQQDAKHILEHIFFQVVEFKKLNQEAH"
     exon            179..266
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /inference="alignment:Splign:2.1.0"
     exon            267..396
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /inference="alignment:Splign:2.1.0"
     exon            397..472
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /inference="alignment:Splign:2.1.0"
     exon            473..544
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /inference="alignment:Splign:2.1.0"
     exon            545..671
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /inference="alignment:Splign:2.1.0"
     exon            672..761
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /inference="alignment:Splign:2.1.0"
     exon            762..830
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /inference="alignment:Splign:2.1.0"
     exon            831..985
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1073
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /inference="alignment:Splign:2.1.0"
     exon            1074..1182
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..2083
                     /gene="Ift52"
                     /gene_synonym="RGD1311004"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agccacgcct tctcggcgcg cggccttgga tacctggcgg cctctggcct caggtaacca
       61 tggagaagga gctgaggagt accattcttt tcaatgcata caaaaaggag gtgtttacca
      121 ccaacactgg ctacaaatct ttgcagaaaa gacttcggag taattggaag attcagagct
      181 taaaagatga aatcacttct gagaagttaa ttggggtgaa actatggatc acagctggac
      241 caagggaaaa gtttactgct gcagagtttg aagtcctgaa gaagtacctt gacagtggtg
      301 gggacatcct tgtgatgctg ggagaagggg gagaatccag atttgatacc aatattaact
      361 tccttctaga agaatatgga atcatggtta ataatgatgc tgtggttaga aatgtgtatt
      421 acaagtattt ccatcctaag gaagctctgg tttcagacgg agtgttgaac agagagatta
      481 gccgagctgc agggaaggct gtgcctggag tcattgatga agagaacagt ggaaacaatg
      541 cccaggctct cacctttgtc tacccttatg gtgccacatt gagcgtcatg aaaccagcag
      601 tggctgttct gtccacaggc tctgtctgct tcccactgaa caggcccatt ctggctttct
      661 atcactcaaa gaaccaaggt tttggaaagc tggcagtgct gggctcgtgt catatgttca
      721 gtgaccaata tttagataaa gaagaaaata gcaaaattat ggacgttgtg ttccagtggc
      781 tcacaacagg agacatccac ctaaaccaga ttgatgctga ggacccagag atttccgact
      841 acacgatggt gccagacaca gccacccttt cagagcagct ccgagtgtgt ctccaggaag
      901 gcgatgagaa cccccgtgac tttaccaccc tctttgacct gtccatttac cagctggaca
      961 ccacctgcct ccccaaggtc atcaaggctc acgaggaact aaatgtgaag catgaaccac
     1021 tgcagctcgt ccaacctcag tttgagatgc cgctgccagc ccttcagcct gcggtcttcc
     1081 ctccaagttt ccgggagctg ccaccccctc ccctggagct gtttgaccta gatgaaacat
     1141 tctcttctga gaaggcacgc cttgctcaga tcaccaacaa gtgtactgat gaagacctgg
     1201 aattctatgt caggaagtgt ggtgacattc ttggagtaac aagcaaactt ccaaaagatc
     1261 aacaggatgc caaacatatc cttgagcaca tcttcttcca agtggtggag ttcaagaaac
     1321 tgaaccagga ggcccactga ggtggcagcc cttcaggtga tgttacccac tgttggcaac
     1381 cttcattagt tcttcagtgc ttactaagtg tctcccagat gagcaacaga tgatgatccc
     1441 ttcgagaata gaactcctgt tctagctgga gggtcccaac aaacagtacc aaaatatgta
     1501 agcaaacact tagataccag gtaagtgccc tggtatagaa acaatagagc caggccggag
     1561 ggatctagtg tgccagcatt cagcagagtg agcagagctg gctcagagtc tgctgtgctg
     1621 tctgtgtcag agccttcaac agcacttgtg tgacacgtgg ttgctgtctg tggtcgtgag
     1681 cagagtccgt cctggagtgt gagaacttca tcctgggctt agaatcagcc ttcaggccgg
     1741 ctaaccccac ttgtccagct aacggtgatt ctgaatgtcg aattaatgtt ccaaatacca
     1801 aagagttcct atttcaggct cggacctgaa ataaaatgaa attctgtttc ctgtctcatc
     1861 ctggaacgtg acgttgatgt ggctgaagtg acattccaga acttccgagg actatagagc
     1921 agcttctgcc cgccgagctc tgtgcttctg aattcttctc acgaaagtat ctgtacttgg
     1981 ttttctctaa cgctgtggat ggtttgccca tcctctgtag tgccagatgg aagagatgat
     2041 tcatttgctt aaattaaatc tgtgattgaa cttttgtaat tta
//
