LOCUS       NM_001024760            1569 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Rattus norvegicus intraflagellar transport 46 (Ift46), mRNA.
ACCESSION   NM_001024760 XM_217120
VERSION     NM_001024760.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1569)
  AUTHORS   Liew,G.M., Ye,F., Nager,A.R., Murphy,J.P., Lee,J.S., Aguiar,M.,
            Breslow,D.K., Gygi,S.P. and Nachury,M.V.
  TITLE     The intraflagellar transport protein IFT27 promotes BBSome exit
            from cilia through the GTPase ARL6/BBS3
  JOURNAL   Dev Cell 31 (3), 265-278 (2014)
   PUBMED   25443296
REFERENCE   2  (bases 1 to 1569)
  AUTHORS   Ishikawa,H., Ide,T., Yagi,T., Jiang,X., Hirono,M., Sasaki,H.,
            Yanagisawa,H., Wemmer,K.A., Stainier,D.Y., Qin,H., Kamiya,R. and
            Marshall,W.F.
  TITLE     TTC26/DYF13 is an intraflagellar transport protein required for
            transport of motility-related proteins into flagella
  JOURNAL   Elife 3, e01566 (2014)
   PUBMED   24596149
  REMARK    Erratum:[Elife. 2014 Apr 01;3:e02897. doi: 10.7554/eLife.02897..
            PMID: 24692455]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1569)
  AUTHORS   Lai,C.K., Gupta,N., Wen,X., Rangell,L., Chih,B., Peterson,A.S.,
            Bazan,J.F., Li,L. and Scales,S.J.
  TITLE     Functional characterization of putative cilia genes by high-content
            analysis
  JOURNAL   Mol Biol Cell 22 (7), 1104-1119 (2011)
   PUBMED   21289087
REFERENCE   4  (bases 1 to 1569)
  AUTHORS   Follit,J.A., Xu,F., Keady,B.T. and Pazour,G.J.
  TITLE     Characterization of mouse IFT complex B
  JOURNAL   Cell Motil Cytoskeleton 66 (8), 457-468 (2009)
   PUBMED   19253336
REFERENCE   5  (bases 1 to 1569)
  AUTHORS   Gouttenoire,J., Valcourt,U., Bougault,C., Aubert-Foucher,E.,
            Arnaud,E., Giraud,L. and Mallein-Gerin,F.
  TITLE     Knockdown of the intraflagellar transport protein IFT46 stimulates
            selective gene expression in mouse chondrocytes and affects early
            development in zebrafish
  JOURNAL   J Biol Chem 282 (42), 30960-30973 (2007)
   PUBMED   17720815
  REMARK    GeneRIF: Characterization of a similar gene in mouse and zebrafish.
REFERENCE   6  (bases 1 to 1569)
  AUTHORS   Hou,Y., Qin,H., Follit,J.A., Pazour,G.J., Rosenbaum,J.L. and
            Witman,G.B.
  TITLE     Functional analysis of an individual IFT protein: IFT46 is required
            for transport of outer dynein arms into flagella
  JOURNAL   J Cell Biol 176 (5), 653-665 (2007)
   PUBMED   17312020
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097954.1.
            
            On Jun 13, 2005 this sequence version replaced XM_217120.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097954.1, BC079388.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1569
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q22"
     gene            1..1569
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /note="intraflagellar transport 46"
                     /db_xref="GeneID:300675"
                     /db_xref="RGD:1307682"
     exon            1..214
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /inference="alignment:Splign:2.1.0"
     exon            215..311
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /inference="alignment:Splign:2.1.0"
     exon            312..388
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /inference="alignment:Splign:2.1.0"
     CDS             347..1252
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /note="intraflagellar transport protein IFT46;
                     intraflagellar transport 46 homolog"
                     /codon_start=1
                     /product="intraflagellar transport protein 46 homolog"
                     /protein_id="NP_001019931.1"
                     /db_xref="GeneID:300675"
                     /db_xref="RGD:1307682"
                     /translation="MADNSSDEYEEDNKEKKKPSQLTPQQGFSENDDDDDDDSSETDS
                     DDDDDDEEHGAPLEGAYDPADYEHLPVSAEIKELFEYISRYTPQLIDLDHKLKPFIPD
                     FIPAVGDIDAFLKVPRPDGKPDHLGLLVLDEPSTKQSDPTVLSLWLTENSKQHNITQH
                     MKVKSLEDAEKNPKAIDTWIESISELHRSKPPATVHYTRPMPDIDTLMQEWSPEFEEL
                     LGKVSLPTVEIDCSLAEYIDMICAILDIPFYKSRIQSLHLLFSLYSEFKNSQHFKALA
                     EGKKTFTPPSNSASQAGDAETLSFL"
     exon            389..522
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /inference="alignment:Splign:2.1.0"
     exon            523..597
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /inference="alignment:Splign:2.1.0"
     exon            598..691
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /inference="alignment:Splign:2.1.0"
     exon            692..820
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /inference="alignment:Splign:2.1.0"
     exon            821..942
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1009
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1070
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1156
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1545
                     /gene="Ift46"
                     /gene_synonym="RGD1307682"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggcgaagg gagtaggggg cggggccgta ggtctcgcga tcattcctct tggctctcgc
       61 tttgttttgt tttatttatc tttttgccta acgactgaca actggcggct tgttgagctt
      121 agggatcctt gaagtggccg ggcctgagag tgagacccca gtcctaggct ggggttcttt
      181 ccaaatagag gaaacggatc ccgaagggct acagaccaaa attgttgaga accagacata
      241 tgatgagcgt ctagagatta acgactcgga agaggttgcc agtattagca ctccaacccc
      301 aggacatcaa ggccctcctt tttctgccgc tcttcccagc aaggtgatgg ctgataacag
      361 cagtgatgag tacgaggagg acaacaagga gaagaagaag ccctcacagc tgacccctca
      421 gcaaggcttc agtgagaatg atgacgacga tgacgatgac tcctctgaga ccgactctga
      481 tgacgatgac gacgacgagg agcatggagc acccctggaa ggggcctatg atcctgcgga
      541 ctatgagcat ctgccagtct cggctgagat caaggagctc tttgagtaca ttagccggta
      601 cacacctcag ttgattgatc tggaccacaa actgaaacct ttcattcctg attttatccc
      661 agctgttggg gatatcgatg catttttaaa ggtgccgcgt cctgatggaa agcctgacca
      721 cctgggcctc ttggttttag atgaaccgtc taccaagcag tcggacccta ccgtgctttc
      781 cctgtggtta acagagaatt ccaagcagca taacattacg caacatatga aagtaaagag
      841 cctagaggat gcagaaaaga atcccaaagc cattgacacc tggattgaga gcatctctga
      901 gttacaccgt tccaagcccc ctgcgactgt gcactacacc aggcccatgc ctgacattga
      961 cactctgatg caggagtggt cccctgagtt tgaagagctc ctgggaaagg tgagtctgcc
     1021 cactgtcgag atcgattgca gcctggctga gtacattgac atgatctgtg ccatcctgga
     1081 cattcctttc tacaagagcc ggattcagtc cctccacctg ctcttttccc tctactcaga
     1141 attcaagaat tcccagcatt ttaaagctct tgctgaaggc aagaaaacat tcactcctcc
     1201 atccaactct gcctcccagg ctggagatgc ggagacactg agtttcctct gagcctcctc
     1261 ttggggctgt gcttcaaagt caggtgaaca tggtctctgt tggcagctta acatctccct
     1321 gctccacagt tgggccctgg ccacacaagt cctgctgcct tgtctttgag agcagggcac
     1381 acctgggcta cacctgcctc cctttgcctt tcccgaggaa ggatgtgtcc acactgctgt
     1441 gggcagctga gttggaagaa ctgggactcc gagagcctca gaacttccag agacacacag
     1501 actgttctgt caggttatga tggaatatat attggttttc acccaaaaaa aaaaaaaaaa
     1561 aaaaaaaaa
//
