LOCUS       NM_001131002             735 bp    mRNA    linear   ROD 14-APR-2024
DEFINITION  Rattus norvegicus intraflagellar transport 25 (Ift25), transcript
            variant 1, mRNA.
ACCESSION   NM_001131002 XM_001060588 XM_001066126
VERSION     NM_001131002.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Desai,P.B., San Agustin,J.T., Stuck,M.W., Jonassen,J.A., Bates,C.M.
            and Pazour,G.J.
  TITLE     Ift25 is not a cystic kidney disease gene but is required for early
            steps of kidney development
  JOURNAL   Mech Dev 151, 10-17 (2018)
   PUBMED   29626631
REFERENCE   2  (bases 1 to 735)
  AUTHORS   Liu,H., Li,W., Zhang,Y., Zhang,Z., Shang,X., Zhang,L., Zhang,S.,
            Li,Y., Somoza,A.V., Delpi,B., Gerton,G.L., Foster,J.A., Hess,R.A.,
            Pazour,G.J. and Zhang,Z.
  TITLE     IFT25, an intraflagellar transporter protein dispensable for
            ciliogenesis in somatic cells, is essential for sperm flagella
            formation
  JOURNAL   Biol Reprod 96 (5), 993-1006 (2017)
   PUBMED   28430876
REFERENCE   3  (bases 1 to 735)
  AUTHORS   Ishikawa,H., Ide,T., Yagi,T., Jiang,X., Hirono,M., Sasaki,H.,
            Yanagisawa,H., Wemmer,K.A., Stainier,D.Y., Qin,H., Kamiya,R. and
            Marshall,W.F.
  TITLE     TTC26/DYF13 is an intraflagellar transport protein required for
            transport of motility-related proteins into flagella
  JOURNAL   Elife 3, e01566 (2014)
   PUBMED   24596149
  REMARK    Erratum:[Elife. 2014 Apr 01;3:e02897. PMID: 24692455]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 735)
  AUTHORS   Keady,B.T., Samtani,R., Tobita,K., Tsuchya,M., San Agustin,J.T.,
            Follit,J.A., Jonassen,J.A., Subramanian,R., Lo,C.W. and Pazour,G.J.
  TITLE     IFT25 links the signal-dependent movement of Hedgehog components to
            intraflagellar transport
  JOURNAL   Dev Cell 22 (5), 940-951 (2012)
   PUBMED   22595669
REFERENCE   5  (bases 1 to 735)
  AUTHORS   Follit,J.A., Xu,F., Keady,B.T. and Pazour,G.J.
  TITLE     Characterization of mouse IFT complex B
  JOURNAL   Cell Motil Cytoskeleton 66 (8), 457-468 (2009)
   PUBMED   19253336
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC162011.1.
            
            On or before Aug 15, 2008 this sequence version replaced
            XM_001066126.1, XM_001060588.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC162011.1, FM089040.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132264
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q34"
     gene            1..735
                     /gene="Ift25"
                     /gene_synonym="Hspb11"
                     /note="intraflagellar transport 25"
                     /db_xref="GeneID:685284"
                     /db_xref="RGD:1596413"
     exon            1..84
                     /gene="Ift25"
                     /gene_synonym="Hspb11"
                     /inference="alignment:Splign:2.1.0"
     exon            85..163
                     /gene="Ift25"
                     /gene_synonym="Hspb11"
                     /inference="alignment:Splign:2.1.0"
     exon            164..276
                     /gene="Ift25"
                     /gene_synonym="Hspb11"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..610
                     /gene="Ift25"
                     /gene_synonym="Hspb11"
                     /note="Hspb11 heat shock protein family B (small), member
                     11; heat shock protein beta-11"
                     /codon_start=1
                     /product="intraflagellar transport protein 25 homolog"
                     /protein_id="NP_001124474.1"
                     /db_xref="GeneID:685284"
                     /db_xref="RGD:1596413"
                     /translation="MRKVDLCSSTEGTEVILATSSDEKHPPENIIDGNPETFWTTTGM
                     FPQEFIICFHKHVKIEKLVIQSYLVRTLRIEKTTSKEPLDFEQWVEKDLVHTEGQLQN
                     EEIMARDGYATFLRFIIVSAFDHFASVHSISAEGLTVSSLP"
     exon            277..383
                     /gene="Ift25"
                     /gene_synonym="Hspb11"
                     /inference="alignment:Splign:2.1.0"
     exon            384..452
                     /gene="Ift25"
                     /gene_synonym="Hspb11"
                     /inference="alignment:Splign:2.1.0"
     exon            453..496
                     /gene="Ift25"
                     /gene_synonym="Hspb11"
                     /inference="alignment:Splign:2.1.0"
     exon            497..710
                     /gene="Ift25"
                     /gene_synonym="Hspb11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcgagcgga ctgggtcctt tcgcagagct actcgaggcc caagcgagcg ggtctgtgca
       61 gcacggtggg cgggcaccga agaggtcatt cggtagagtt tgggagtctt tcctgcactc
      121 gttttgctgc tggggacaca acccaggact tcttgcatat aaggctacac attttgagat
      181 gaggaaggtg gatctctgct cgagcactga agggacagaa gtgattctgg ccacgtcgag
      241 tgatgaaaag cacccgcctg aaaacatcat tgacgggaat ccagaaacct tttggaccac
      301 cacaggcatg tttccccagg agttcattat ttgtttccac aaacacgtaa agattgaaaa
      361 gcttgtgatt caaagttact tggtgcggac tttgaggatt gaaaagacca catctaaaga
      421 gccattggat tttgagcagt gggttgaaaa agatttagta cacacagagg ggcagcttca
      481 aaatgaagaa attatggcac gagatggcta cgccactttc ttgagattca ttattgtctc
      541 agcgtttgat cattttgcat ctgtgcacag catttctgca gagggactga cagtctcaag
      601 tcttccttag tgattacaac agcatgctct gaactacttt tagaatatat ttattgaaac
      661 acaaagctat ctttgatatg tttactatta aatagatttg tatcactctg aaaaaaaaaa
      721 aaaaaaaaaa aaaaa
//
