LOCUS       NM_001105815            1126 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus intraflagellar transport 20 (Ift20), mRNA.
ACCESSION   NM_001105815 XM_001080863 XM_213403
VERSION     NM_001105815.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1126)
  AUTHORS   Schmid FM, Schou KB, Vilhelm MJ, Holm MS, Breslin L, Farinelli P,
            Larsen LA, Andersen JS, Pedersen LB and Christensen ST.
  TITLE     IFT20 modulates ciliary PDGFRalpha signaling by regulating the
            stability of Cbl E3 ubiquitin ligases
  JOURNAL   J Cell Biol 217 (1), 151-161 (2018)
   PUBMED   29237719
REFERENCE   2  (bases 1 to 1126)
  AUTHORS   Zhang Z, Li W, Zhang Y, Zhang L, Teves ME, Liu H, Strauss JF 3rd,
            Pazour GJ, Foster JA, Hess RA and Zhang Z.
  TITLE     Intraflagellar transport protein IFT20 is essential for male
            fertility and spermiogenesis in mice
  JOURNAL   Mol Biol Cell 27 (23), 3705-3716 (2016)
   PUBMED   27682589
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   3  (bases 1 to 1126)
  AUTHORS   Onnis A, Finetti F, Patrussi L, Gottardo M, Cassioli C, Spano S and
            Baldari CT.
  TITLE     The small GTPase Rab29 is a common regulator of immune synapse
            assembly and ciliogenesis
  JOURNAL   Cell Death Differ 22 (10), 1687-1699 (2015)
   PUBMED   26021297
REFERENCE   4  (bases 1 to 1126)
  AUTHORS   Ferraro S, Gomez-Montalvo AI, Olmos R, Ramirez M and Lamas M.
  TITLE     Primary cilia in rat mature Muller glia: downregulation of IFT20
            expression reduces sonic hedgehog-mediated proliferation and
            dedifferentiation potential of Muller glia primary cultures
  JOURNAL   Cell Mol Neurobiol 35 (4), 533-542 (2015)
   PUBMED   25504432
  REMARK    GeneRIF: IFT20 ablation impairs the dedifferentiation capacity of
            Muller cells induced by Shh and by glutamate.
REFERENCE   5  (bases 1 to 1126)
  AUTHORS   May-Simera HL, Petralia RS, Montcouquiol M, Wang YX, Szarama KB,
            Liu Y, Lin W, Deans MR, Pazour GJ and Kelley MW.
  TITLE     Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the
            cochlea
  JOURNAL   Development 142 (3), 555-566 (2015)
   PUBMED   25605782
REFERENCE   6  (bases 1 to 1126)
  AUTHORS   Yoshimura S, Egerer J, Fuchs E, Haas AK and Barr FA.
  TITLE     Functional dissection of Rab GTPases involved in primary cilium
            formation
  JOURNAL   J Cell Biol 178 (3), 363-369 (2007)
   PUBMED   17646400
REFERENCE   7  (bases 1 to 1126)
  AUTHORS   Hou Y, Qin H, Follit JA, Pazour GJ, Rosenbaum JL and Witman GB.
  TITLE     Functional analysis of an individual IFT protein: IFT46 is required
            for transport of outer dynein arms into flagella
  JOURNAL   J Cell Biol 176 (5), 653-665 (2007)
   PUBMED   17312020
REFERENCE   8  (bases 1 to 1126)
  AUTHORS   Follit JA, Tuft RA, Fogarty KE and Pazour GJ.
  TITLE     The intraflagellar transport protein IFT20 is associated with the
            Golgi complex and is required for cilia assembly
  JOURNAL   Mol Biol Cell 17 (9), 3781-3792 (2006)
   PUBMED   16775004
  REMARK    GeneRIF: This work suggests that IFT20 functions in the delivery of
            ciliary membrane proteins from the Golgi complex to the
            cilium.[IFT20]
REFERENCE   9  (bases 1 to 1126)
  AUTHORS   Jurczyk A, Gromley A, Redick S, San Agustin J, Witman G, Pazour GJ,
            Peters DJ and Doxsey S.
  TITLE     Pericentrin forms a complex with intraflagellar transport proteins
            and polycystin-2 and is required for primary cilia assembly
  JOURNAL   J Cell Biol 166 (5), 637-643 (2004)
   PUBMED   15337773
REFERENCE   10 (bases 1 to 1126)
  AUTHORS   Baker SA, Freeman K, Luby-Phelps K, Pazour GJ and Besharse JC.
  TITLE     IFT20 links kinesin II with a mammalian intraflagellar transport
            complex that is conserved in motile flagella and sensory cilia
  JOURNAL   J Biol Chem 278 (36), 34211-34218 (2003)
   PUBMED   12821668
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_213403.4, XM_001080863.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BP483765.1, FM074465.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1126
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q25"
     gene            1..1126
                     /gene="Ift20"
                     /gene_synonym="RGD1309400"
                     /note="intraflagellar transport 20"
                     /db_xref="GeneID:287541"
                     /db_xref="RGD:1309400"
     exon            1..181
                     /gene="Ift20"
                     /gene_synonym="RGD1309400"
                     /inference="alignment:Splign:2.1.0"
     exon            182..413
                     /gene="Ift20"
                     /gene_synonym="RGD1309400"
                     /inference="alignment:Splign:2.1.0"
     CDS             341..814
                     /gene="Ift20"
                     /gene_synonym="RGD1309400"
                     /note="intraflagellar transport 20 homolog"
                     /codon_start=1
                     /product="intraflagellar transport protein 20 homolog"
                     /protein_id="NP_001099285.1"
                     /db_xref="GeneID:287541"
                     /db_xref="RGD:1309400"
                     /translation="MTYLLIDTITPSKQNFSREPGRETAMAKDILGEAGLHFDELNKL
                     RVLDPEVTQQTTELKEECKDFVDKIGQFQKIVGGLIELVDQLAKEAENEKMKAIGARN
                     LLKSIAKQREAQQQQLQALIAEKKMQLERYRVEYEALCKVEAEQNEFIDQFIFQK"
     exon            414..542
                     /gene="Ift20"
                     /gene_synonym="RGD1309400"
                     /inference="alignment:Splign:2.1.0"
     exon            543..628
                     /gene="Ift20"
                     /gene_synonym="RGD1309400"
                     /inference="alignment:Splign:2.1.0"
     exon            629..732
                     /gene="Ift20"
                     /gene_synonym="RGD1309400"
                     /inference="alignment:Splign:2.1.0"
     exon            733..1126
                     /gene="Ift20"
                     /gene_synonym="RGD1309400"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgtgttgcct ctatttccca gcaaacacct cggggagggc ggatagtagt gcttctggtc
       61 ttgggagtga cgtgtggttt ataggtccag tatccgtggc agccgccgat tgcagttact
      121 gaagagaagc ttctaccgac agtcgtctgg gccgcagcgc gctgtcgaga cggctcggca
      181 gctaaactgt gctgctccag ggcaggcacc atgctgcatt catctttaca ccccagcatc
      241 tagcagtgtc ggcatgtagt aggcactcaa gaaatgtatg ctgaatgaac gatgcctgtg
      301 acaagcaact ggactttatt ctttcctgac ccttgctcct atgacatacc tcctgattga
      361 cactatcacc ccttcaaagc agaacttctc tagggagcct ggaagggaaa cagctatggc
      421 caaggacatc ttgggtgagg cagggctgca cttcgatgag ctgaacaagc ttcgggtgtt
      481 ggacccagag gttacccagc agaccacaga gctcaaggaa gagtgcaagg actttgtgga
      541 caaaattggc cagtttcaga aaatcgttgg tggtctgatt gagcttgttg atcagcttgc
      601 caaagaagca gagaacgaga aaatgaaggc cattggtgct cgaaacttgc tgaaatccat
      661 agcgaagcag agagaagccc agcaacagca actgcaggca ctgatagcag aaaagaagat
      721 gcagctagaa aggtatcggg ttgaatatga agctttgtgt aaagtagaag cagaacaaaa
      781 tgaatttatt gaccaattta tttttcagaa atgaactgaa aatttcagtt ttatagcagg
      841 aaggcaaaaa aaaaaaaaaa aaaaaaaaaa gaaaagaaaa aaaagaaaga aaaaaagcac
      901 ctcaaccaaa aaacaaagac caaacctcta ccattccagt gatttgatgt atgtcacggc
      961 agtgctccag gggcagctgg taaactgtgc agccactgct agtggccaag cagcacaggg
     1021 ccttactctt ctcagcacaa actaagtgtc tgtaaatgct gatccacttt tttgggagag
     1081 gtagttaaat tcacaaggaa aagcaataaa taccaaataa atactt
//
