LOCUS       NM_001014786             579 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus interferon, alpha 5 (Ifna5), mRNA.
ACCESSION   NM_001014786 XM_216443
VERSION     NM_001014786.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 579)
  AUTHORS   Hu,G., Xue,J., Duan,H., Yang,Z., Gao,L., Luo,H., Mu,X. and Cui,S.
  TITLE     IFN-gamma induces IFN-alpha and IFN-beta expressions in cultured
            rat intestinal mucosa microvascular endothelial cells
  JOURNAL   Immunopharmacol Immunotoxicol 32 (4), 656-662 (2010)
   PUBMED   20214528
  REMARK    GeneRIF: IFN-gamma is able to activate rat intestinal mucous
            microvascular endothelial cells, thereby leading to upregulated
            expressions of IFN-alpha/beta.
REFERENCE   2  (bases 1 to 579)
  AUTHORS   van der Meide,P.H., Dijkema,R., Caspers,M., Vijverberg,K. and
            Schellekens,H.
  TITLE     Cloning, expression, and purification of rat IFN-alpha 1
  JOURNAL   Methods Enzymol 119, 441-453 (1986)
   PUBMED   3020354
REFERENCE   3  (bases 1 to 579)
  AUTHORS   Dijkema,R., Pouwels,P., de Reus,A. and Schellekens,H.
  TITLE     Structure and expression in Escherichia coli of a cloned rat
            interferon-alpha gene
  JOURNAL   Nucleic Acids Res 12 (2), 1227-1242 (1984)
   PUBMED   6320120
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X00336.1.
            
            On Apr 20, 2005 this sequence version replaced XM_216443.2.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..579
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q32"
     gene            1..579
                     /gene="Ifna5"
                     /gene_synonym="IFN-alpha1; Ifna1; Ifna1l1"
                     /note="interferon, alpha 5"
                     /db_xref="GeneID:298210"
                     /db_xref="RGD:1359312"
     CDS             1..579
                     /gene="Ifna5"
                     /gene_synonym="IFN-alpha1; Ifna1; Ifna1l1"
                     /note="interferon-alpha 1; interferon-alpha 1-like 1"
                     /codon_start=1
                     /product="interferon alpha-1 precursor"
                     /protein_id="NP_001014786.1"
                     /db_xref="GeneID:298210"
                     /db_xref="RGD:1359312"
                     /translation="MARLCAFLMSLVVVSYWSACCLGCDLPHTHNLRNKRVFTLLAQM
                     RRLSPVSCLKDRKYFGFPLEKVDGQQIQKAQAIPVLHELTQQILSLFTSKESSTAWDA
                     TLLDSFCNDLQQQLSGLQACLMQQVGVQESPLTQEDSLLAVREYFHRITVYLRENKHS
                     PCAWEVVKAEVWRALSSSANLMGRLREERNES"
     exon            1..579
                     /gene="Ifna5"
                     /gene_synonym="IFN-alpha1; Ifna1; Ifna1l1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggctcggc tctgtgcttt cttgatgtcc ctggtggtgg tgagctactg gtcagcctgc
       61 tgtctaggat gtgacctgcc tcatactcat aacctcagga acaagagagt cttcacactc
      121 ctggcacaaa tgaggagact ctcccctgtc tcatgcctga aggacagaaa gtactttggg
      181 ttccctttgg agaaggtgga tggccagcag atccagaagg ctcaagctat ccctgtcctg
      241 catgagctga cccagcagat cctcagcctc ttcacatcaa aggagtcatc tactgcttgg
      301 gatgcaaccc tcctagactc attctgtaat gacctccagc agcagctgag tggtctgcaa
      361 gcctgtctga tgcagcaggt aggggtgcag gaatctcccc tgacccagga agactcccta
      421 ctggctgtga gggaatactt ccacagaatc actgtgtacc tgagagagaa taaacacagc
      481 ccctgtgcct gggaggtggt caaagcagaa gtctggagag ccctgtcttc ctcagccaac
      541 ttgatgggaa gactgagaga agaaagaaat gagtcctga
//
