LOCUS       NM_001007694            2042 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus interferon-induced protein with tetratricopeptide
            repeats 3 (Ifit3), mRNA.
ACCESSION   NM_001007694 XM_220059
VERSION     NM_001007694.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2042)
  AUTHORS   Fensterl V and Sen GC.
  TITLE     Interferon-induced Ifit proteins: their role in viral pathogenesis
  JOURNAL   J Virol 89 (5), 2462-2468 (2015)
   PUBMED   25428874
  REMARK    Review article
REFERENCE   2  (bases 1 to 2042)
  AUTHORS   Archambaud C, Nahori MA, Soubigou G, Becavin C, Laval L, Lechat P,
            Smokvina T, Langella P, Lecuit M and Cossart P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   3  (bases 1 to 2042)
  AUTHORS   Liu XY, Chen W, Wei B, Shan YF and Wang C.
  TITLE     IFN-induced TPR protein IFIT3 potentiates antiviral signaling by
            bridging MAVS and TBK1
  JOURNAL   J Immunol 187 (5), 2559-2568 (2011)
   PUBMED   21813773
REFERENCE   4  (bases 1 to 2042)
  AUTHORS   Pichlmair A, Lassnig C, Eberle CA, Gorna MW, Baumann CL, Burkard
            TR, Burckstummer T, Stefanovic A, Krieger S, Bennett KL, Rulicke T,
            Weber F, Colinge J, Muller M and Superti-Furga G.
  TITLE     IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA
  JOURNAL   Nat Immunol 12 (7), 624-630 (2011)
   PUBMED   21642987
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2042)
  AUTHORS   Stawowczyk M, Van Scoy S, Kumar KP and Reich NC.
  TITLE     The interferon stimulated gene 54 promotes apoptosis
  JOURNAL   J Biol Chem 286 (9), 7257-7266 (2011)
   PUBMED   21190939
REFERENCE   6  (bases 1 to 2042)
  AUTHORS   Burckstummer T, Baumann C, Bluml S, Dixit E, Durnberger G, Jahn H,
            Planyavsky M, Bilban M, Colinge J, Bennett KL and Superti-Furga G.
  TITLE     An orthogonal proteomic-genomic screen identifies AIM2 as a
            cytoplasmic DNA sensor for the inflammasome
  JOURNAL   Nat Immunol 10 (3), 266-272 (2009)
   PUBMED   19158679
REFERENCE   7  (bases 1 to 2042)
  AUTHORS   Huang X, Shen N, Bao C, Gu Y, Wu L and Chen S.
  TITLE     Interferon-induced protein IFIT4 is associated with systemic lupus
            erythematosus and promotes differentiation of monocytes into
            dendritic cell-like cells
  JOURNAL   Arthritis Res Ther 10 (4), R91 (2008)
   PUBMED   18706081
REFERENCE   8  (bases 1 to 2042)
  AUTHORS   Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A,
            Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala
            S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW,
            Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver
            P, Ingram DK, de Cabo R and Sinclair DA.
  TITLE     Resveratrol improves health and survival of mice on a high-calorie
            diet
  JOURNAL   Nature 444 (7117), 337-342 (2006)
   PUBMED   17086191
REFERENCE   9  (bases 1 to 2042)
  AUTHORS   Xiao S, Li D, Zhu HQ, Song MG, Pan XR, Jia PM, Peng LL, Dou AX,
            Chen GQ, Chen SJ, Chen Z and Tong JH.
  TITLE     RIG-G as a key mediator of the antiproliferative activity of
            interferon-related pathways through enhancing p21 and p27 proteins
  JOURNAL   Proc Natl Acad Sci U S A 103 (44), 16448-16453 (2006)
   PUBMED   17050680
REFERENCE   10 (bases 1 to 2042)
  AUTHORS   Smith JB and Herschman HR.
  TITLE     The glucocorticoid attenuated response genes GARG-16, GARG-39, and
            GARG-49/IRG2 encode inducible proteins containing multiple
            tetratricopeptide repeat domains
  JOURNAL   Arch Biochem Biophys 330 (2), 290-300 (1996)
   PUBMED   8660659
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JACYVU010000047.1.
            
            [WARNING] On Mar 28, 2024 this sequence was replaced by
            NM_001007694.3.
            
            On Nov 27, 2020 this sequence version replaced NM_001007694.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079079.1, FQ182240.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-156               JACYVU010000047.1  19134959-19135114
            157-2042            JACYVU010000047.1  19138219-19140104
FEATURES             Location/Qualifiers
     source          1..2042
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q53"
     gene            1..2042
                     /gene="Ifit3"
                     /note="interferon-induced protein with tetratricopeptide
                     repeats 3"
                     /db_xref="GeneID:309526"
                     /db_xref="RGD:1359681"
     exon            1..156
                     /gene="Ifit3"
                     /inference="alignment:Splign:2.1.0"
     CDS             152..1387
                     /gene="Ifit3"
                     /codon_start=1
                     /product="interferon-induced protein with
                     tetratricopeptide repeats 3"
                     /protein_id="NP_001007695.1"
                     /db_xref="GeneID:309526"
                     /db_xref="RGD:1359681"
                     /translation="MSEVNKESLEKILPQLKCHFTWNLFKEGSISSHMEDRVCNQIEN
                     LNSEHKATMYDLLAYIKHLDGENEAALECLGQAEDLRKSERSDRAEIKCLVTWGNYAW
                     IYYRIGQLSEAQAYADKVRQVCQKFANPYSMECPELDCEEGWTRLKCGRNERAKMCFE
                     KALEEKPEDPECRAGMAIAMYRLQEKPEKQFSVDALKQAMELNSQNQYEKVLLALKLQ
                     KMGEEAEAERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSP
                     LYSLVMCRYREKLKQLQNTGEADKSERRQTMEELRRLTMEYMNKALQRRPSPLNSYSD
                     LIDFPEVEKCYQMVFSEESPRAEDQELFERYCNLQEYHRKSEGLKALKDLMQFPRPEK
                     STEKEEVKQQTQNGDLNLQ"
     exon            157..2042
                     /gene="Ifit3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagaaacagc aggacatcag ctgatgagtt tctcccccac cctctgcccc cttatataat
       61 cgtctgagtg cccactttcg gtgaactgag atttctgaac tgttcagccc acacccagct
      121 tttcacagca gcatagaaac agatcgccgt catgagtgag gtcaacaagg agtctctgga
      181 aaaaatcctt cctcaactta agtgccattt cacctggaat ttattcaagg aaggaagcat
      241 ctcaagtcat atggaagaca gggtgtgtaa ccagatcgaa aatttaaact ctgagcacaa
      301 agcgacaatg tatgacttac tggcctatat aaagcaccta gatggtgaga acgaggccgc
      361 cctggaatgc ttagggcaag ctgaagattt acggaagtca gagcgcagtg atcgagcaga
      421 gattaaatgt ctggtcacct ggggaaacta tgcttggatc tactaccgca ttggccagct
      481 ctcagaagct caggcgtacg ctgacaaggt gagacaagtt tgccaaaagt ttgcaaatcc
      541 ttacagcatg gaatgcccag aacttgactg tgaggaagga tggacacgcc taaagtgtgg
      601 aagaaatgaa cgagctaaga tgtgcttcga aaaggctcta gaggagaagc ccgaggatcc
      661 agagtgcagg gctggaatgg ccattgccat gtaccgccta caggaaaaac cggagaagca
      721 gttctctgtg gatgctctga aacaggccat ggagttgaat tctcagaacc agtacgagaa
      781 ggttctcctg gctctgaaac tgcagaagat gggggaagaa gctgaagcag agcggttggt
      841 tgaagatgcc ttggaaaagg gtcctaatca aacagacgtc ctccaaaagg cagctcagtt
      901 ctataggaaa aagggtaacc tagacagagc tattgaattc cttggaaaag cactgagatc
      961 cacagcaaac aacagtcccc tctacagctt ggtcatgtgc cgttacaggg aaaaactgaa
     1021 gcaactgcag aatacaggag aggctgacaa gagtgagaga agacagacta tggaagaact
     1081 gagaagatta actatggagt acatgaataa ggctcttcag aggaggccaa gtcctctgaa
     1141 ctcctactca gacctcatcg atttcccgga agtagagaaa tgctatcaga tggtcttcag
     1201 cgaggagagc cctcgcgctg aggaccaaga actctttgag cgctattgca acctccagga
     1261 gtatcacagg aagtctgaag gcctcaaagc cctgaaggat ctcatgcagt ttcccagacc
     1321 tgaaaaatcc accgagaagg aagaagttaa acagcaaacg cagaacggag atcttaacct
     1381 gcagtaggaa tttttgctgg attgttggca tttccaggga aaaaatgaga agctggatgg
     1441 gtgagggatg tgggaggcaa cacgatttgg ggtgcaggca gcctattcct gacatcctat
     1501 gagcctgata acaaccggaa gtgtgtcagc gtgcagacac tcagccctga gctgtgagag
     1561 agatgtgctg tgaagtgatg catacagaga ggaaagggct ggaaaagcag gagccttcct
     1621 gccaaggatc catgacaagc agctcttgac tgtttcttta aaaacctgct ttctctccct
     1681 gactcctctg ctcatcctaa ctgtagaatt ttccactcag tagatcttat tactaatcat
     1741 gtagggaaat ggggcttaag gcttaaagtg caccttttga tcacaatttt tctctgcaat
     1801 atatggcaac agccaacaaa atttagtctg gtttcttcat tccatttcac tgtagtcact
     1861 taaacctgaa ggattcactt ttgcccaacc ctagaatatt ctgtgcatat catccttata
     1921 ttctaccgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtatcccta
     1981 acagtgatcc tgcagtatgc caaattgaaa ttgtagaata aatttaaaag tttcaactaa
     2041 aa
//
