LOCUS       NM_020096               2174 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus interferon-induced protein with tetratricopeptide
            repeats 1 (Ifit1), mRNA.
ACCESSION   NM_020096
VERSION     NM_020096.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2174)
  AUTHORS   Fensterl V and Sen GC.
  TITLE     Interferon-induced Ifit proteins: their role in viral pathogenesis
  JOURNAL   J Virol 89 (5), 2462-2468 (2015)
   PUBMED   25428874
  REMARK    Review article
REFERENCE   2  (bases 1 to 2174)
  AUTHORS   Archambaud C, Nahori MA, Soubigou G, Becavin C, Laval L, Lechat P,
            Smokvina T, Langella P, Lecuit M and Cossart P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   3  (bases 1 to 2174)
  AUTHORS   Pichlmair A, Lassnig C, Eberle CA, Gorna MW, Baumann CL, Burkard
            TR, Burckstummer T, Stefanovic A, Krieger S, Bennett KL, Rulicke T,
            Weber F, Colinge J, Muller M and Superti-Furga G.
  TITLE     IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA
  JOURNAL   Nat Immunol 12 (7), 624-630 (2011)
   PUBMED   21642987
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2174)
  AUTHORS   Daffis S, Szretter KJ, Schriewer J, Li J, Youn S, Errett J, Lin TY,
            Schneller S, Zust R, Dong H, Thiel V, Sen GC, Fensterl V, Klimstra
            WB, Pierson TC, Buller RM, Gale M Jr, Shi PY and Diamond MS.
  TITLE     2'-O methylation of the viral mRNA cap evades host restriction by
            IFIT family members
  JOURNAL   Nature 468 (7322), 452-456 (2010)
   PUBMED   21085181
REFERENCE   5  (bases 1 to 2174)
  AUTHORS   Li HT, Su YP, Cheng TM, Xu JM, Liao J, Chen JC, Ji CY, Ai GP and
            Wang JP.
  TITLE     The interaction between interferon-induced protein with
            tetratricopeptide repeats-1 and eukaryotic elongation factor-1A
  JOURNAL   Mol Cell Biochem 337 (1-2), 101-110 (2010)
   PUBMED   19856081
REFERENCE   6  (bases 1 to 2174)
  AUTHORS   Burckstummer T, Baumann C, Bluml S, Dixit E, Durnberger G, Jahn H,
            Planyavsky M, Bilban M, Colinge J, Bennett KL and Superti-Furga G.
  TITLE     An orthogonal proteomic-genomic screen identifies AIM2 as a
            cytoplasmic DNA sensor for the inflammasome
  JOURNAL   Nat Immunol 10 (3), 266-272 (2009)
   PUBMED   19158679
REFERENCE   7  (bases 1 to 2174)
  AUTHORS   Kitamura Y, Spleiss O, Li H, Taniguchi T, Kimura H, Nomura Y and
            Gebicke-Haerter PJ.
  TITLE     Lipopolysaccharide-induced switch between retinoid receptor (RXR)
            alpha and glucocorticoid attenuated response gene (GARG)-16
            messenger RNAs in cultured rat microglia
  JOURNAL   J Neurosci Res 64 (6), 553-563 (2001)
   PUBMED   11398178
REFERENCE   8  (bases 1 to 2174)
  AUTHORS   Bluyssen HA, Vlietstra RJ, Faber PW, Smit EM, Hagemeijer A and
            Trapman J.
  TITLE     Structure, chromosome localization, and regulation of expression of
            the interferon-regulated mouse Ifi54/Ifi56 gene family
  JOURNAL   Genomics 24 (1), 137-148 (1994)
   PUBMED   7896268
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AJ276893.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ276893.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2174
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q53"
     gene            1..2174
                     /gene="Ifit1"
                     /gene_synonym="Garg16"
                     /note="interferon-induced protein with tetratricopeptide
                     repeats 1"
                     /db_xref="GeneID:56824"
                     /db_xref="RGD:620599"
     CDS             92..1483
                     /gene="Ifit1"
                     /gene_synonym="Garg16"
                     /function="unknown"
                     /note="glucocorticoid-attenuated response gene 16 product"
                     /codon_start=1
                     /product="interferon-induced protein with
                     tetratricopeptide repeats 1-like protein"
                     /protein_id="NP_064481.1"
                     /db_xref="GeneID:56824"
                     /db_xref="RGD:620599"
                     /translation="MGENAGGDQVMENLLQLRCHFTWGLLFEKNDIPDLEVRISEQVQ
                     FLDIKNSLGMHNLQAYVRHLKGEQEEALQSLKEAEALIEGEQLGKRSLVTWGNCAWVH
                     YHRGSLAEAQIYLDKVENVCREFSSPFRYRMECAEIDCEEGWALLKCGGSNYMRAMAC
                     FAKALQVDPENPEYNAGYAVVAYRQDFDDNHVSLEPLRKAVRLNPEDPHLKVLLALKL
                     QDLGEQDEAETHIEEALSSTSCQSYVFRYAAKYFRRKGDINEALHLLHRALQTSPSSG
                     YLHYQKGLCYKQQMIQLKTSGNRQARRQENIQELAHQAICEFQETLNLRPTFEMAYVC
                     MAEMQAEIGQYEEAEGNFQEALNLNNLVAHIEQDIHFRYGRSQQFHKKSEDKAITHYL
                     KGLKLEEKSFAWRKLLTALEKVAERRVRQNVRLVESTSLLGLVFKLKGQEMKALLYYE
                     KALRLSGEMNPAF"
ORIGIN      
        1 tacggggggg ggggggccag agagcagagt caaggccagt ctctgaagag tcctcctccg
       61 ctcttgaaca gctaccacct tcacagcaac catgggagag aatgctggtg gtgaccaggt
      121 catggagaat ctgcttcagc tgagatgtca cttcacatgg ggcctgctct tcgaaaaaaa
      181 tgacatacct gatttggaag tgaggatctc agagcaggtc cagttccttg acatcaagaa
      241 ctcactgggg atgcacaacc tccaggccta cgtgagacac ctgaaaggtg agcaggagga
      301 agccctgcag agcttgaaag aggctgaagc cttgatcgag ggagagcagt tgggcaagag
      361 aagcctggtg acctggggca actgtgcctg ggtgcattac cacaggggca gcttggcaga
      421 agcccagatc tacctggaca aggtggagaa tgtttgcagg gaattctcaa gtcccttccg
      481 ctacaggatg gagtgtgctg agatagactg tgaggaaggc tgggccttgc tgaagtgtgg
      541 aggaagtaac tatatgcgag ccatggcctg ctttgcaaag gctctgcagg tggacccaga
      601 aaaccctgag tacaatgctg gctatgcagt tgtggcctat cgccaagatt tcgatgacaa
      661 ccatgtttct ctagaacctc taaggaaggc tgtcaggtta aatccagaag atccacacct
      721 taaagttctc cttgctctaa agcttcagga tttaggggaa caagatgaag cagaaacaca
      781 cattgaagaa gccctcagca gcacatcttg ccaaagctat gtctttcgct acgcagccaa
      841 atatttccgc cggaaaggtg acataaacga agctcttcat cttctacaca gggccttgca
      901 gacgtcacct tcctctggct acctacatta ccaaaaaggg ctctgttaca agcaacagat
      961 gatccaactg aagacatctg gaaacaggca ggccagaagg caggagaata tacaggaatt
     1021 ggcacatcag gccatttgtg aatttcaaga gactttgaat ctgaggccca catttgagat
     1081 ggcttacgtt tgcatggctg aaatgcaggc agaaattggc caatatgaag aagcagaggg
     1141 aaatttccag gaggccctga acctcaacaa ccttgtagcc cacatagagc aggatattca
     1201 tttccgctac ggccgttccc aacaatttca taagaagtca gaagacaagg caatcactca
     1261 ctacttaaaa ggtctaaaac tagaagagaa gtcctttgcc tggaggaaac tactcacagc
     1321 tttggagaaa gtggctgaaa gacgtgttcg ccagaatgtc cggcttgtgg agagcaccag
     1381 ccttcttgga ctggtcttca aactgaaagg gcaggagatg aaggccctgc tttactatga
     1441 gaaggccctg aggctctctg gggaaatgaa ccctgcattt tgaatgcagc ttacctttgt
     1501 gaagttaata tactcacaac taagtgttct aatgctccct cctgacttct tttcccagat
     1561 ctgctttgct gaaatgccac gtagctaagt acattttctc ctgcgacttc tttatggctc
     1621 tcgtgatcct gtctaaaggc actttccctt cccttaagac acctgctcac tttaaagaat
     1681 cattgacccg attccttggt gttcccaact tccttggtga gtaacaaaaa tcaagaacct
     1741 ttttccccta tgtctgggcc tttggaacaa atattttttc ccactgccaa atgtcttgga
     1801 ccaaaaaacc ttcgctgaaa aaggtttcgg gttttcttgg ttgttgtttt ttctttttta
     1861 tgtcacaaga aacactcatt accatacaat ttcaggcaaa acaaataagc aaagaggaaa
     1921 gtttgaaagc aaaagaggtc acccttactg gaaaaatatt aacaaccaag aagacgtttg
     1981 gcttactgga gaattaaaat gaaaactctt cttaggtagt aaagcctgaa aattgcataa
     2041 gtaacttctt ttaatatttg aatgctaaaa atattccttg aaagtgaccc agtaacaaat
     2101 ttggtagagt ctgctggtgc cattgtaaag gacgcacctc tatgtttgca tggtttcttg
     2161 gttatctttc atcc
//
