LOCUS       XM_008769938            3106 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus alpha-L-iduronidase (Idua), transcript
            variant X3, mRNA.
ACCESSION   XM_008769938
VERSION     XM_008769938.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051349.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_008769938.4.
            
            On Jan 21, 2021 this sequence version replaced XM_008769938.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3106
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3106
                     /gene="Idua"
                     /note="alpha-L-iduronidase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 25
                     ESTs, 3 long SRA reads, 2 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 55 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:360904"
                     /db_xref="RGD:1310943"
     CDS             304..1953
                     /gene="Idua"
                     /codon_start=1
                     /product="alpha-L-iduronidase isoform X3"
                     /protein_id="XP_008768160.1"
                     /db_xref="GeneID:360904"
                     /db_xref="RGD:1310943"
                     /translation="MEERLKSSGQGLIYNFTHLDAFLDLLMENQLLPGFELMGSPSGY
                     FTDFEDKQQVFEWKDLVSLLARRYIGKYGLTNVSKWNFETWNEPDHHDFDNVSMTTQG
                     FLNYYDACSEGLRIASPTLRLGGPGDSFHPLPRSPMCWSLLGHCANGTNFFTGEVGVR
                     LDYISLHKKGAGSSIAILEQEVAVVEQIQQLFPKFKDTPIYNDEADPLVGWSLPQPWR
                     ADVTYAALVVKVIAQHQNLLFANSSSSMRYILLSNDNAFLSYHPYPFSQRTLTARFQV
                     NNTHPPHVQLLRKPVLTVMGLMALLDGEQLWAEVLKAGAVLDSNHTVGVLASTHHPEG
                     PSEAWRTTVLIYTSDDTHIHPNDSIPVILHLRGVPPGLELVYVVLYLDNQLSSPYSAW
                     QHMGQPVFPSAEQFRQMRMVEDPVAEAPRPFPARGRLTLYRKLPVPSLMLVHLCARPL
                     EPPGQVSRLRALPLTRGQLVLVWSDEHVGSKCLWTYEIQFSQKGEVYAPINRRPSTFN
                     LFVFSPDTAVVSGFYRVRAVDYWARPGPFSDPVTYLDTPAS"
ORIGIN      
        1 gaccaggctg accagtacga ccttagttgg gaccagcaac tgaaccttgc ctacataggt
       61 gctgtgcctc acagtggcat tgagcaggtc cggatacact ggctgctgga cctcatcaca
      121 gccagggcat ggtggtgact attggagcca attgtgcctg gcctgggtac tgggatagca
      181 gcttccccag tgcggtggtt gttcaacagg catcctagct cttgaggaac attatgagag
      241 caatgacaca taagggtcat tgaacacccg aggctcaccc caagtgtcta ggggctcagt
      301 tgtatggaag aaagactgaa gtcatcaggc cagggattga tctacaactt cacccacttg
      361 gatgcattcc tggacctcct catggaaaac cagcttctcc cgggatttga gctaatgggc
      421 agtccttctg ggtacttcac ggactttgag gacaagcagc aggtgtttga atggaaagac
      481 ctggtttctc tcttggccag gagatacatt ggtaagtatg ggctgacaaa tgtttccaag
      541 tggaactttg aaacttggaa cgaaccagac caccatgact ttgacaacgt gtccatgacc
      601 acacaaggct tcctgaatta ctatgacgct tgctctgagg ggctgcgcat tgccagccct
      661 actttgaggc tgggtggtcc tggggattcc ttccaccccc tgccaaggtc accaatgtgc
      721 tggagcctcc tgggacactg tgccaacgga accaacttct tcactggtga ggtgggcgtc
      781 cgcctagatt acatctccct gcacaagaag ggtgcaggca gctccatcgc catcctggag
      841 caggaggtgg cagtcgtgga gcagatccag cagctcttcc ccaagttcaa ggacacccct
      901 atttataatg acgaggcaga ccctctggta ggctggtccc tgccgcaacc ttggagagcc
      961 gatgtgactt atgccgccct agtggtgaag gtcatcgcac agcaccagaa cctgctgttt
     1021 gccaacagca gctcctccat gcgctacata ctcctcagca atgacaatgc cttcctgagc
     1081 taccacccgt accctttctc ccagcgtaca cttactgctc gcttccaggt caacaatact
     1141 cacccacccc acgtgcagtt gctgcggaag ccagtactca cagtcatggg gctgatggcc
     1201 ctgttggatg gagagcaact ctgggcagag gtcttgaagg ctggggctgt gttggacagc
     1261 aaccatacag tgggtgtcct ggccagcacc catcaccctg aaggtccctc agaggcctgg
     1321 agaaccactg tcctgatcta cactagtgat gacacccaca tacaccctaa cgacagtatc
     1381 cctgttattc ttcatctgcg tggagtacct cctggcttgg agcttgtcta cgtagtactc
     1441 tacttagaca atcaactcag cagcccctac agtgcatggc agcacatggg ccagccagtc
     1501 ttcccctctg cagagcagtt ccgacaaatg cgcatggtgg aggacccagt ggctgaggca
     1561 ccgcgcccat ttcctgctag gggccgcctg accctgtacc gtaaacttcc agtgccatct
     1621 ctcatgctgg ttcatttatg cgcacgcccc ttggagccac cagggcaggt cagccggctc
     1681 cgtgcactgc ccctgacacg tgggcagctg gttctggtct ggtcggatga gcatgtgggc
     1741 tccaagtgcc tgtggacata tgagatccag ttttcccaga agggtgaagt atatgcccca
     1801 atcaacagga ggccgtctac ttttaaccta tttgtgttca gccccgacac agctgtggtc
     1861 tctggcttct accgagtgcg agcagtggac tactgggccc ggccgggccc cttctccgac
     1921 cctgtgactt acctggatac ccctgcctcc tgaaaaccac tgactcccag agactggtga
     1981 aaggagtcag ccaggatgag ctagactgcc atcaactaag cagctgacta gtagcttctt
     2041 ttgttgtccc cctatttcct ttaaggtgtc tttctctacc tcagacttgg ggtcagcctt
     2101 tgtggatgag cactttactg gcccacttgg agtgaccttt gcccaccttc ctcctgggga
     2161 gatggctcag tgggtaaagt gcttgctgtg caggcacgag gacttgtgtt cagagatcta
     2221 gcactcatgt aaagtagggc atggcaatat atgcctagtg ccctagtgtt ggtggaaggg
     2281 acagggacag gccagagctc actggccatc tagtctaccc gaaactgcaa gttccgggtt
     2341 cagtaagaaa ccctgtttta gaaaaatcaa gtagagagct tggtgtacac gtgcgcacac
     2401 acacgcacac aaacacacac atgcacacac atacatcaca ccatgcacgc agtctgaatt
     2461 ctgtaattaa aaaataaatg caaacacgtc tttctgaaat acaattgcat agagtaaaca
     2521 tttccaacag gtcaaataaa tgacagggga ggatttaaat gaaacaagac caaaacacgg
     2581 caagacaaac attaaatcct gcagatccat tctcagcact ggggcacatg ttattgtgat
     2641 atgagctcta acgtgctgga cagtctgtgt ctgtggtgtg tcattttcag cccctctgac
     2701 ctttctccta ggctggtgtc ttaggcgttc tattgatgtg ataaaacatg atgagcttaa
     2761 gcagctggag tagaaaagca tttattgtac tcttatttct acattatagt ctatcatcga
     2821 aggaagtcag gcaggagctt ggaggcagga agtcatgtag aggccatggc tgctcactct
     2881 caagggctcg ctcagactat gttcttacac actccaggat caccaaccaa agggcaggcc
     2941 ccacccacaa tggtctggac cctcccacat caacctaatt aagaaaacag gctcacccat
     3001 aggtcagtcc tgttggggca tttttctcaa ctgaggttcc ttcttcccaa atgactgtag
     3061 cttgtcacaa attgaaataa aaccatccca accatgccac acatta
//
