LOCUS       XM_039100540            4930 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus iduronate 2-sulfatase (Ids),
            transcript variant X2, mRNA.
ACCESSION   XM_039100540
VERSION     XM_039100540.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051356.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039100540.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4930
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4930
                     /gene="Ids"
                     /note="iduronate 2-sulfatase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 152
                     ESTs, 7 long SRA reads, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 137
                     samples with support for all annotated introns"
                     /db_xref="GeneID:363513"
                     /db_xref="RGD:1560491"
     CDS             473..1735
                     /gene="Ids"
                     /codon_start=1
                     /product="iduronate 2-sulfatase isoform X2"
                     /protein_id="XP_038956468.1"
                     /db_xref="GeneID:363513"
                     /db_xref="RGD:1560491"
                     /translation="MSVGKVFHPGISSNHSDDYPYSWSFPPYHPSSEKYENTKTCKGQ
                     DGKLHTNLLCPVDVADVPEGTLPDKQSTEEAIRLLEKMKTSVSPFFLAVGYHKPHIPF
                     RYPKEFQKLYPLENMTLAPDPHVPDSLPPVAYNPWMDIREREDVQALNISVPYGPIPV
                     DFQRKIRQSYFASVSYLDTQVGHLLSALDDLRLAHNTIIAFMSDHGWALGEHGEWAKY
                     SNFDVTTRVPLMFYVPGKTALLPAAGEKLFPYQDPFDPASELMGAGRRTEDLVELVSL
                     FPTLAGLAGMPVPPWCPIPSFHVELCREGHNLQRYLQLHDLEEDPYLFGNPRELIAYS
                     QYPRPADFPQWNSDKPSLKDIKVMGYSIRTIDYRYTVWVGFSPTEFLANFSDIHAGEL
                     YFVDSDPLQDHNVYNDSQHGGLLLSLRP"
ORIGIN      
        1 gcgttcaagc cagcgcccgg gccttcgggc ccgaggcgtc gcgtcggtgt cgcgcagtct
       61 tctctgagac agtcgcgggc tgtggaggcc gcgacgacgg cagcggcggc ggcggcggcg
      121 gcggcggcgg cggcggcggc ggcggctacg gctacctaat ggtcctgatg tagccgtacc
      181 ttctcgcaag gctgtgctga ggaagaaatg tcgccgccgc cgccgccgcc accaactacc
      241 tggcgccagc ttagcttcag cttgttgcta ggcttcttct gtatcgccct ggtgtccgca
      301 gcgcaaggca actctgctac agcaagcagt gtgtgcacca agtcgagttt ccttcctcac
      361 cgggaggagg cctgacacca cccgcctgta tgacttcaat tcctactgga gggtacactc
      421 tggaaatttt tccaccatcc cccaatactt caaggagaat ggctacgtga ccatgtcggt
      481 tgggaaagtc tttcaccctg gtatatcttc caatcacagt gatgattatc catatagttg
      541 gtcttttcca ccttatcatc catcctccga gaagtatgaa aacactaaga catgtaaggg
      601 acaagatgga aaactccaca ccaacctgct ttgtcctgtg gatgtggcag atgtgcctga
      661 gggtaccttg cctgacaaac agagcacaga ggaagccatt cgattgttgg aaaagatgaa
      721 aacgtcagtc agtcctttct tcctggcggt cgggtatcac aagccacaca tccccttcag
      781 ataccctaag gaatttcaga agttgtatcc cctggaaaac atgaccctgg ctcctgatcc
      841 ccatgttcct gatagcctac cacctgtagc ctacaacccg tggatggaca tcagggagcg
      901 ggaagatgtc caagccttaa acatcagtgt tccctatgga ccaattcctg tggattttca
      961 gcggaaaatc cgccagagct actttgcttc tgtgtcctat ttggatacac aggtcgggca
     1021 tcttttgagt gctttggatg atctccgtct ggcccacaac acaattattg ctttcatgtc
     1081 tgatcatgga tgggccctag gtgaacacgg agaatgggcc aaatacagca actttgatgt
     1141 cactacccgt gtaccactga tgttttatgt tcctggaaag acagccctcc ttcctgcagc
     1201 aggagagaag ctctttcctt accaggaccc ttttgatccc gcttcagaat tgatgggtgc
     1261 aggcaggcgc actgaggacc tcgtagaact tgtgtctctc ttccccacgc tcgctggact
     1321 tgcaggaatg ccagttcctc cttggtgccc catcccttct tttcatgttg agctgtgcag
     1381 agaaggccat aatctccaga ggtatttgca gctccatgac ttggaagagg atccatactt
     1441 gtttggtaat ccccgggagt tgattgccta cagccagtat ccccggcctg cagatttccc
     1501 tcagtggaat tctgacaagc caagcttaaa agatataaag gtcatgggat actccatacg
     1561 caccatagac tataggtata ctgtgtgggt tggcttcagt cctactgagt ttctggctaa
     1621 cttttctgat atccatgctg gggaactcta ttttgtcgat tctgacccac tgcaggatca
     1681 caatgtatat aatgactccc aacatggagg tcttctcctc tcactgagac cttgagttct
     1741 gccagcctca gagagcagat atgcgtcccc ttccccgtct ttatggtgaa aggaggcatt
     1801 agagatggta tcttttccta cccgttgtat tagacataac ctgagtggga aacaatcaaa
     1861 acatgaatca gcaatctggc ctatgagtag gtggcaatgg atcttttcct atagtcctta
     1921 agttagattt tgccattgga tttgggctaa gctaaaactt ccatttttaa aagctcccat
     1981 agctcattac tatacaagtg caaagtgaac taaagtaaaa tcatatcttt atatctaaag
     2041 accatgctaa ccagacataa tactttactc aagaaattgt ttgcttattg aatttaatgc
     2101 ttttcatata gtaaccatat gtcttaagta gcccagtgtg tcaagcatgt taacatgtga
     2161 ttcatttctt tctcatatgt aaaattaaag ttgtttctag aattattact tagttcctaa
     2221 gactacagat ttcaaaatca atggtaaaat acccatgaga tgatcaatgc agtgttttgt
     2281 cattaaataa tgcttagtaa attatagtta aagctaggaa attcagttaa ctattttgat
     2341 attctctggc ctaaataata atttattagt aaatagtaca actattgaac tcagaggcta
     2401 tctgccaaaa attctattat tcacaatgaa aagcatttaa aatggaagta ttaccatgat
     2461 ttgaatcatt cagaattgta ttcatattcc tatttagaga attgcagata tctatgtatc
     2521 ctggaggcag gaggtattct actttttgct aaagaaaaca tgtttatgaa atgtaaatta
     2581 tcttgaggct tatggaaact tttcactaat aaggtataag taatgtccag aatgtagttc
     2641 taaattcgca agtacaaaag taagtagaag ggtatgtagt gaggataaag ttatttcatt
     2701 gctgtcatca aagagaagcc ctttgtctaa catggtgaga actgctccat taccagctgt
     2761 ccacagcttt ctaaatcaac attctttgta tttgcttttg tatttaaatg agtaatttca
     2821 ataattttct taaaaatgcc cgtgttcaag gcaaatgttt ttaaaacaaa aatacaacaa
     2881 atagctagtt aaattattga catgtattaa attgtaacca aaaagtcaag gtattacttt
     2941 gaacagtgta aaatttcaga gacagcgttg tttttcccag ttgcctgtag aagactggta
     3001 gctgacaatc cattgttttc ccctgagcaa ttaagtagct gtcttggcaa cagcagtttg
     3061 cattgctggt ttgggattga tggtcccatt catctctcct gatccccaga ttggtctgtt
     3121 gtctagaaac tgactgttgc accgtctttt cttgttcttg atctttatgg ctctcatgat
     3181 gtccactcag catcagtttt acaatttagt ttagaaattt ctcacagcat gctttcattt
     3241 tgtttagctc tgtttgtttc tcctacttga tggttagagg gacagatttt gacacaagtt
     3301 tttatctttt atctatttat tatttctgtt tgatcatagt atatatactt catttttttt
     3361 aatgtcccaa agcacagttt tagtgttaaa ctcacctgaa ttctgttttc attgtagtta
     3421 taaggccagt ggtggccaca tgatatatat ggctatttaa atttaaatta gttgacacaa
     3481 aataacattt gaaaagattt ctggtatgtt ataatttaca cttagaacct tcccatcata
     3541 gcagactgga cagagatgcc ctggattcga gctagaagtg ttcaccgtga ttggcaggtt
     3601 cctactgtcg tgtatttgcc cacagtgagc aaactctatt tggtttaggc agagtcggcc
     3661 tagagtgtgt tgtggccatc agcttcttcc ttccactctc atcaccattg cttttgtcct
     3721 tctttctttc cttcccaaga aatttacctc ccttcctttt tcctcccccg ttcctgaagg
     3781 aatccatgtg tcttcctaaa atccctcttg acccctgccc tttaagaaca ccgtcagtgc
     3841 ctactaaggg tctagcaaga cctccgctga gcagtcagag tcttccctgg ctccacaatg
     3901 ccccttccct tggctgactc tccttgccaa tccttacctc cctggtcctt ccagcctttg
     3961 tcccttcttc tttgctccaa ccccttcatt gccattcttc ataacctggc tcccttaccc
     4021 ccctgcttag aggctgaggc tgtcaggact ctctagactg tatgaggggg gaatttgagt
     4081 acatcttaaa aaatgtggta tttgcttcac tttttaaaag gcatttttct ctcattatga
     4141 gtttgatatg ttaattatac aacaattgga aagcagaaat gcatttaaag gcaagaaaat
     4201 gtctgagtgc tttatactaa gattgccata tcttgtcctt tttggggtat gaatgtttta
     4261 catttattga tcctctatgt ttttttataa tacaacttct gctcttactt tctctctaaa
     4321 catcatgtat ggctactagt gatttttgca gatatttcat attgctggta atatatgtta
     4381 ttgcattgat ttattgtaat tttctcaacc ttctttcagt tgttagaaat ttaggttatt
     4441 tccaagtttt cagtattacg aatagtgctg tgatcaattt tgtgaataca gtgtttttat
     4501 atattttaaa gtattcccat acgctaattt ctcagtacca agtcatcaaa aacagctctg
     4561 ttttctcttt gcttgctatg atagcatatt aaacttagaa aagaaactca aaagacctat
     4621 attaaaaaac tataatacca aaaaagaaac tctgtagtcc cataataata agtgaaagtt
     4681 gtattctgtt ttgacgtctg attctttgtt gattaataac atgaaccatt attctctctg
     4741 tatggtagtt gtgcagttgc atttccagtt gtgtgactgt gtggaaatgt tatgagtctt
     4801 attacctttt agtgtaataa agtaaatttc ttttttcctg tgtgatagtt tttcctgtat
     4861 atttgttcta agcacagaac aactccattt gcgttgaata aaaatgaata aatactcatt
     4921 ttcctttgaa
//
