LOCUS       XM_006256260            3467 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus inducible T-cell co-stimulator ligand
            (Icoslg), transcript variant X1, mRNA.
ACCESSION   XM_006256260
VERSION     XM_006256260.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051355.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006256260.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006256260.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3467
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3467
                     /gene="Icoslg"
                     /note="inducible T-cell co-stimulator ligand; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 19 ESTs, 5 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     102 samples with support for all annotated introns"
                     /db_xref="GeneID:499415"
                     /db_xref="RGD:1562791"
     CDS             208..1155
                     /gene="Icoslg"
                     /codon_start=1
                     /product="ICOS ligand isoform X1"
                     /protein_id="XP_006256322.1"
                     /db_xref="GeneID:499415"
                     /db_xref="RGD:1562791"
                     /translation="MQLNRFFSGPGLFLLLFCSLCVEAEVKEVNAMVGSDVELRCVYP
                     RRSHFSLDDLYVYWQIVDEAKTVVTYYLPSANESSTIHVSNSYKNRAHLSPDLMKEGD
                     FSLHLQNVTPQDTQEFKCLVFRMSTVLGKALEEVVRLRVAANFSTPVISTSGSSDPGQ
                     ERTFTCMSKNGYPEPNLYWINRTDNTLIDETLQNNTVYLNELGLYDVVSTLRIPWTPH
                     VDVICCVENVALHQNITSISRADSFTGSMNTERPQEIHREATKVLFYVLAALLAVVVV
                     IFIIVLYRCRRRPCQSYTGPRAVQLELTGECTCGERPVG"
ORIGIN      
        1 gattgtgccc aattggccag gcgcgcagcg cttgcgagcg cagttacagc ctgtctcctg
       61 ccggcgaagc ctcaacaacc ccagatttcc gcgccccaaa tccttgaagc cccccaaatt
      121 ctccgtgggc tccgaggact tcggaacccc agcagctgca gctctccact ctccgaggtc
      181 cagcaccccg aagtctgctc tcgcactatg cagctaaaca ggttcttttc cggtcctggt
      241 ctgtttttgc tgctattttg cagtctctgt gtcgaggctg aagttaaaga agtcaatgca
      301 atggtgggga gcgatgtgga gctccgctgc gtttatcctc ggagaagcca tttcagcttg
      361 gatgatctgt atgtctactg gcaaatcgtc gatgaagcta aaactgtggt gacgtattac
      421 ctgcccagtg ctaacgagtc ttcgacaatc catgtgagca actcctacaa gaacagggcc
      481 catctgtcac cggacctcat gaaggagggc gacttctccc tgcacctgca gaatgtcacc
      541 cctcaggata cccaggagtt caagtgcttg gtctttagga tgtccacagt gttaggcaag
      601 gccttggaag aggtggtcag actgcgtgtg gcagcaaact tcagtacgcc tgtcatcagc
      661 acctctggca gctctgaccc tggccaggaa cgcaccttca cttgcatgtc caagaatggc
      721 tacccagagc ccaacctgta ttggatcaac aggacggaca ataccctaat agacgagact
      781 ctgcagaata acacggtcta cttgaacgag ttgggcctgt atgacgtcgt cagcacactg
      841 aggatccctt ggacacccca tgtggatgtt atctgctgtg tagagaatgt ggctctccac
      901 cagaacatta ctagtatcag ccgggcagat agtttcactg gaagcatgaa cacagagagg
      961 ccacaggaaa tccacagaga ggctacaaag gtccttttct acgtcctagc tgcacttctg
     1021 gcggtagtgg ttgtcatttt catcatcgtg ctgtacagat gcaggcgtcg tccctgccag
     1081 agctatacag gacccagggc tgtacagctt gaactcacag gtgagtgtac ctgtggggag
     1141 aggccggttg gctgagtggt cgtgaccttt cacacctccg gtgggcagtt ttccatactt
     1201 gatgattcca gagttgcaga aaccctgtcc tgtggcagaa gctcttggac cgtgcatagc
     1261 agacagcctg tcataggtcc ctgggtccct cctgcctctg ctctgcagaa cccatagact
     1321 gtgactctgg cagtccagag tcccttggtg gaggtgtaca ctctgtaatt ggaaggacag
     1381 tcgcaggtgg attccgcaat ctccagaggt gtggattcac atcctgattt tagaaaaaca
     1441 cctcagaggt tttggttgac cactaagaga tacatatccc tggctctaag tatttttact
     1501 acctcaaagt gactgcacct tcctgaaccc ggcttttcca cggtagagat gtcggtatgt
     1561 gtggtcccct cggtgcgttg gggcctgttg gctgacaccc accacccccc actccctttg
     1621 aagcctgaat tctgggccac ctcgtcctta cccagtcatg aggctgtact agccagctgt
     1681 ttctagttat cagcctgagt cccgggaaga atcatttcat tgtctccaaa attaaaactt
     1741 tgcatggttc cagtagagtg agcttaccag gcaggcacga ggaagcaggg cctgccttca
     1801 tctttctctc tcttccttcc aagaccattc ctgacagaac tctgcccagg atgtggacag
     1861 ggtttctaat ggactcccgc aggcctggtg acagaggaca atgagctgtc tgcttacgtg
     1921 ctgtgatgaa ggccaggaat ccctggcttt ccgaggcttg atcccagaaa cccccgaggg
     1981 agatctcttc cagtgggcgg tgtcatcaga ctgtggagcc tcccgtgagc acagagagga
     2041 agcagcttgt gagaagatcc ttctcctgcc agatactcag tcccaggatc tttgaaagag
     2101 ggcatttgag ccactccgaa agcacctaca aaatctactg gagactgttt ccctgcagga
     2161 ccttccgtga gggaggaagc ttgactttat ttcagtctca agctcgttgg gcctcctaga
     2221 ggatatgtat ggggttctgt ctacagaaaa cctgctgctg gctgacaatg actgggctca
     2281 gagattaggg gcactcggcc ttgcaacatc aacgggacat gcctcaaggc aaaatatggc
     2341 ccgtctgcca cacacaagtg cttctccatc attgaaggcc ctcaaacctg acttgtggtg
     2401 gatataaaag cttctcgaaa gccttgagct ctttcagtct gaacacaaaa cgggaggtca
     2461 gctccactca gtctcagcag cccatggaga cctcagctcc tgtgtcctgg gtctctccac
     2521 gttgttggcc aaaatagagc tagatgtttt gttttccaga tggttccgca aagttggctg
     2581 cttggaaaca taggtgtgca caagctccag gttgacgcat taggcagcat ggactcacca
     2641 atgggacaca gttccttccc acccagaggc tggacatcct agacagtcgg ggcctgctat
     2701 atggctgggg ctcagtgctg acggatatga gaaatcttcg gaacgaggag tgagaaccct
     2761 gggctcgggc tcaaggggac cagtattatg aagacctgtc cacatggact ctttcttctt
     2821 cgtgtcgact tcttcaatga aacgtctccc tgcaaatgaa gcattactta aacccgtaga
     2881 acagcaactg tccttgtggg tcttgagttg acagctacag taaacgaccg taaggagcag
     2941 ttggggtgca aggagctggg gtgcagtgcc cctaggacag atgtttggga atcagcggcc
     3001 tccccgaggc ccatagttcc aggacacagc catgtctcag ctgtcccagg aactctggtg
     3061 catctatagg gctcttctgt ctactttcac tcccccccac cccccatcag gggtagttta
     3121 gggttagaag aggtcaaccc agtgagccag ccagctgccg tggggcacca gtcactgcac
     3181 ccccccttcc ccatgcctcc tgcttatgtc acactgggaa ccctttatag accactggcc
     3241 ctgtagtcac catcacctgc tgatcccaac agtcccccac cttcctgtgg aatcctggga
     3301 gcaccccccc ccccttaccc ttagcacatc agcattcgtg agacttgccc ttgtaacccc
     3361 tgactccttc agcccagaac cttgcggtca ctctttatct aagtttgtag atggggcata
     3421 gtgacttcca gaaacccggc aagggaataa acataagatg tgctgtc
//
