LOCUS       XM_006245037            1075 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus inducible T-cell co-stimulator (Icos),
            transcript variant X1, mRNA.
ACCESSION   XM_006245037
VERSION     XM_006245037.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051344.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006245037.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006245037.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1075
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..1075
                     /gene="Icos"
                     /gene_synonym="Ailim"
                     /note="inducible T-cell co-stimulator; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 4 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 39 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:64545"
                     /db_xref="RGD:620123"
     CDS             291..941
                     /gene="Icos"
                     /gene_synonym="Ailim"
                     /codon_start=1
                     /product="inducible T-cell costimulator isoform X1"
                     /protein_id="XP_006245099.1"
                     /db_xref="GeneID:64545"
                     /db_xref="RGD:620123"
                     /translation="MKPYFSCVFVFCFLIKLLTGELNDLANHRMFSFHDGGVQISCNY
                     PETVQQLKMQLFKDREVLCDLTKTKGSGNTVSIKNPMSCPYQLSNNSVSFFLDNADSS
                     QGSYFLCSLSIFDPPPFQEKNLSGGYLLIYESQLCCQLKLWLPVGCAAFVAALLFGCI
                     FIVWFAKKKYRSSVHDPNSEYMFMAAVNTNKKSRLAGTAPLRALGRGEHSSCQDRN"
ORIGIN      
        1 agggtcagtc tgacgaggca ggatagagcc tttcccagga agcctttcac ttcctgccga
       61 tccggaggga agaggatgga gttacaagga ccttctgaca gtcaaacaat ggtcctttga
      121 ggtcacagat aaaataattt ctgagcagag aagttagact tctttcccaa gttcctggac
      181 ctggtaaatg atggagccga ctctagaata aaacagaaaa caactgagaa catgatttca
      241 ctgccacttt tgagcactgg aggggaagag tgcagctgtt cctggcagac atgaagccct
      301 acttctcgtg cgtctttgtc ttctgcttcc taatcaaact tttaacagga gaactcaatg
      361 acttggccaa tcacaggatg ttttcgtttc acgatggagg tgtacagatt tcttgtaact
      421 accctgagac tgtccagcag ttaaaaatgc agttgttcaa agacagagaa gtcctctgcg
      481 acctcaccaa gaccaaggga agcggaaaca ccgtgtccat caagaatccg atgtcctgtc
      541 catatcagct gtccaacaac agtgtctctt ttttcctaga caacgcagac agctcccagg
      601 gcagctactt tttatgcagc ctgtcgattt tcgacccacc cccttttcaa gaaaagaacc
      661 ttagtggagg atatttgctt atttatgaat cccagctttg ttgccagctg aagctttggt
      721 tacccgtagg gtgtgcagct tttgtggcag cgctcctttt tggatgcata tttatcgtct
      781 ggtttgcaaa aaagaagtac agatccagtg tgcacgaccc taatagcgag tacatgttca
      841 tggcggcagt caacacaaac aaaaagtcca gacttgcagg tacagcaccc cttagggctt
      901 tggggagagg agaacactct tcatgtcaag accggaatta atttgtttat ttctatttta
      961 aaagaaagac attttttccc ctaaagataa tttttgtatt tttatgtgaa agtctgaatc
     1021 ttcattttaa ctgcacttat atactctgtg gtatattaaa aataatgttt gtgaa
//
