LOCUS       NM_199400               3812 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Rattus norvegicus islet cell autoantigen 1-like (Ica1l), mRNA.
ACCESSION   NM_199400 XM_237197
VERSION     NM_199400.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3812)
  AUTHORS   He,J., Xia,M., Tsang,W.H., Chow,K.L. and Xia,J.
  TITLE     ICA1L forms BAR-domain complexes with PICK1 and is crucial for
            acrosome formation in spermiogenesis
  JOURNAL   J Cell Sci 128 (20), 3822-3836 (2015)
   PUBMED   26306493
  REMARK    GeneRIF: ICA1L forms BAR-domain complexes with PICK1 and is crucial
            for acrosome formation in spermiogenesis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Oct 18, 2022 this sequence version replaced NM_199400.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.50725.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-361               JAXUCZ010000009.1  68963332-68963692   c
            362-540             JAXUCZ010000009.1  68943728-68943906   c
            541-613             JAXUCZ010000009.1  68941955-68942027   c
            614-737             JAXUCZ010000009.1  68934459-68934582   c
            738-936             JAXUCZ010000009.1  68932885-68933083   c
            937-1062            JAXUCZ010000009.1  68928841-68928966   c
            1063-1161           JAXUCZ010000009.1  68926483-68926581   c
            1162-1247           JAXUCZ010000009.1  68924699-68924784   c
            1248-1291           JAXUCZ010000009.1  68922782-68922825   c
            1292-1546           JAXUCZ010000009.1  68914334-68914588   c
            1547-1621           JAXUCZ010000009.1  68912869-68912943   c
            1622-3812           JAXUCZ010000009.1  68906148-68908338   c
FEATURES             Location/Qualifiers
     source          1..3812
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q31-q32"
     gene            1..3812
                     /gene="Ica1l"
                     /note="islet cell autoantigen 1-like"
                     /db_xref="GeneID:316432"
                     /db_xref="RGD:735110"
     exon            1..361
                     /gene="Ica1l"
                     /inference="alignment:Splign:2.1.0"
     exon            362..540
                     /gene="Ica1l"
                     /inference="alignment:Splign:2.1.0"
     CDS             379..1686
                     /gene="Ica1l"
                     /note="islet cell autoantigen 1, 69kDa-like; amyotrophic
                     lateral sclerosis 2 chromosomal region candidate gene 15
                     protein homolog; Ica69-related protein"
                     /codon_start=1
                     /product="islet cell autoantigen 1-like protein"
                     /protein_id="NP_955432.1"
                     /db_xref="GeneID:316432"
                     /db_xref="RGD:735110"
                     /translation="MDSFEHLRPEDSQSVVSRMQKKYWKTKQVFIKATGKKEDEHVVA
                     SDAELDAKLEVFHSIQETCNELVKAVEKYQLRLNVISEEENELGLFLTFQAERDATQA
                     GKMMGAAGKALCSSAKQRLALCTPLSRLKQEVATFSQRAISDTSVTINRMERARTEYR
                     GALLWMKDASQELDPDTFKQVEKFRKVQIQVRNSKDCFDKLKMDVCQKVDLLGASRCN
                     MLSHSLATYQRTLLGFWEKTAQMMSQIQEACAGFHPYDFMALKQLQDTPGNLTAEDKE
                     EQTEGSCLSTNLNKVALSEEEERFEREPAVARALPRDSLEGDDFEKEFSFLSSLLSPT
                     SSRASECTQECQPACGSPSLMCQEPSLGPGPLTSSSQFLPSRLFDLGLHADGAFNSWA
                     SQEGSEHSDTLPVPSQHPKKLKYLGPLSNPDAIGHSDDELLNA"
     exon            541..613
                     /gene="Ica1l"
                     /inference="alignment:Splign:2.1.0"
     exon            614..737
                     /gene="Ica1l"
                     /inference="alignment:Splign:2.1.0"
     exon            738..936
                     /gene="Ica1l"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1062
                     /gene="Ica1l"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1161
                     /gene="Ica1l"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1247
                     /gene="Ica1l"
                     /inference="alignment:Splign:2.1.0"
     exon            1248..1291
                     /gene="Ica1l"
                     /inference="alignment:Splign:2.1.0"
     exon            1292..1546
                     /gene="Ica1l"
                     /inference="alignment:Splign:2.1.0"
     exon            1547..1621
                     /gene="Ica1l"
                     /inference="alignment:Splign:2.1.0"
     exon            1622..3812
                     /gene="Ica1l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgggcgcgg gctcgcgggc ggcggctggg ccggtgcgcg gacgagctcg gcgcggcccg
       61 agcggcgagg agcggcgcgg ctccggcggc gcggtgagcg tccggggtct ggcccgccgc
      121 tcccccaggg cggcgggcgg cggtggccaa acctggttcc catgacgacg gcgggcgggg
      181 gcgcgggccg cgcgctctcg gtgggccggc ctcaggcggc ggcctcaatg ggcctggccc
      241 ctccgcggcg ggggcgtctc ccgcgctccc tccaggggaa gccgcggcct gaggccggcc
      301 ttggagctcc ggatgggggc aaacgttcac agcccggcgt gctttcctgt tggccgcctt
      361 ttctgtttca gttactccat ggattccttt gagcacctca gaccagaaga cagccagtca
      421 gtagtgagca gaatgcagaa gaaatactgg aaaactaagc aggtctttat caaagcgaca
      481 gggaaaaagg aggatgagca cgtggttgca tctgatgcag aactggatgc taaacttgag
      541 gtttttcact ccatccagga gacatgcaat gaactcgtga aggcagttga gaaataccag
      601 ctaagactca atgttatatc agaggaagaa aatgaactag ggctcttttt aacgtttcaa
      661 gcagagcggg atgcaactca agctggcaaa atgatgggcg ccgccggcaa ggccctctgc
      721 tcttcagcca agcaaagact ggccttgtgc actcccctgt ctcgtcttaa gcaagaagtg
      781 gcaacgttca gtcagagggc catctctgac acctcagtga ccatcaaccg catggagcgg
      841 gctcgcaccg agtacagagg ggccctgctg tggatgaaag acgcatcaca ggaacttgac
      901 ccagacacct tcaaacaagt ggagaagttc agaaaagtac agattcaagt gagaaacagc
      961 aaagattgtt tcgacaagtt aaagatggat gtctgtcaga aagtggactt gctgggtgct
     1021 agtcggtgca atatgttatc tcactcactc gctacctacc agagaacatt acttgggttc
     1081 tgggagaaaa cggctcaaat gatgtcccaa atccaagagg cctgtgctgg ctttcatcca
     1141 tatgacttca tggctctcaa gcaactacaa gacactccag gcaatctcac tgcagaggac
     1201 aaagaagaac aaacagaggg cagttgtctt agtacaaacc tcaataaggt agctttgtct
     1261 gaagaggaag agagatttga gagagaacca gcagttgcac gcgctctgcc tagagactca
     1321 ctagaaggag atgattttga gaaggagttc tcatttctga gcagtctcct aagccccacc
     1381 tcttcacgtg ctagtgaatg tacacaggaa tgccagcccg cctgtgggag ccccagcctc
     1441 atgtgccagg agccttcatt aggacccggg cctctcactt cttcctccca gttccttcct
     1501 tcacggcttt ttgaccttgg ccttcatgct gatggagctt tcaacagctg ggcttcccaa
     1561 gagggatcag aacactcaga taccttgcca gtaccttcac agcatccaaa gaaattaaaa
     1621 tacctggggc cactctcaaa cccagatgcc attggacact cagatgacga gcttctgaat
     1681 gcctgactga tgtcatggtg actgacatca cagcttcagg ggtcttgagg aaccaactgt
     1741 gcaacatttg cctttctgaa gagaagttcc cactgcgacc acacacagaa gcatgtgttc
     1801 aggatagaac gtctaccagc caactctagt cacaggattg gagcacctga gcaggctgtg
     1861 gtacttcata tgctgggtgg gcaggctgtt gatagtacat ggataatttt acaaactccg
     1921 caatactgag aaaccaaact tacggctgaa tcacagaagc atggtgtgtt tctttggaag
     1981 gtgttttaca cttgttactt tgctttaagg ggataaagaa taggatagag tggctatagt
     2041 ttggggggtt ttcttgatag tgtcaggtgt tttctgttgt ggggaccagc actagaacta
     2101 taaaaagctt tctcaccaat tacaatgtag aacaagatta gagaactgtc tgctttactg
     2161 aaattaagag aaacgtgggt ttgcttttct gtacctggta actaaatgca atgttaccgt
     2221 tcattcatat gcaatcatgg atacattagt tccattatta aattttcatg gggaagacag
     2281 caggatgcaa aagccatcat ctgtagaaat gggaaaagga atctacaggt ctgtttcact
     2341 gactcttgca gtgctacttt ctctacagaa cagtgaggac aagcattgca tgtctgggca
     2401 gcaatcttgc tgaaacttcc agaaacttct atgtgaacat gcaagacact ttcaaatgcc
     2461 atcataatag ttgtattttc tcaacacaca cttgagccca gaaggatttc tgatagacat
     2521 ggaggattct acagaaagct aaggagcatc ccatgttctt cctttcagtc taactcccac
     2581 agtgccatta gagagtacta agcaaaagct attggcagag gacatagagt ctagggtttg
     2641 aagggaaggc tattcagtgg cagttgggca aactggcgaa atcataactg ctggattgct
     2701 actccttcag cttcctgtcc tttcttgtcc accctttaat ttaagggtag ttctccaagt
     2761 gttctgtcat caagtccatt gtggccagtg tcccacaggg acatcttaag ttgtttattg
     2821 tggtttttat gggcttctag tcattagcag gttgattcaa gttcaaatta catataatgt
     2881 ccaagtcatg gtatataggg agctattttt aagaaaaaaa ccagagtggg tagaatgcca
     2941 tccactccac acattcagaa acctggccta accctgtgga actgaccctg agctgtcaac
     3001 tggtgcaagg gctgcagact cacctgtggg tcagaaacaa atgcagactt gttcctaaat
     3061 atcttcagtc ttaatgaact attacctctt caaaagcact tcccttctgt tcagtgaaaa
     3121 attccagaac acaatattgt cattgttctg ccaagattga tcaccaggat tactataatg
     3181 aatcacagtc tgaggctagg gtccagagca accactgcca ttaacctcaa gaagcaataa
     3241 cttacactgt ctgtgctacc tctctttgcg aggtatcctt ccatgagtta gttcagttat
     3301 gagaacacag ttgtgaacac ttaccagaaa gacagctgat ggggaagcat aggttgtccc
     3361 agagcaactt tgtcaaaaat gggtatcttt tatatcgagt gaagaagcac ctatgttcta
     3421 ctttatttta ttccaaatta gacttcacag aaagttagac agacccaagc acagccacat
     3481 tagccttctc ctcaagagac acaagaatgg caggtcatat gatcagattg gtgtaatttg
     3541 tattttctga gattttaatt gtataatagt gttctaatat cattagaaac aaattgtatt
     3601 taaaattaga tttcattatt tgcacattga aaggagctat atttccactc tgaatattta
     3661 tttcacatta cctattgttc tgggtattta tttcatgttt cctaactaat agatctagaa
     3721 atatacaggg cttacagcat taggaagcta gtttaatgtg ttccctctct cttgagcgtc
     3781 cattaataaa gattacagat ggcataaagc aa
//
