LOCUS       NM_001106823            2504 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus hydroxylysine kinase (Hykk), mRNA.
ACCESSION   NM_001106823 XM_001072720 XM_236254
VERSION     NM_001106823.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2504)
  AUTHORS   Veiga-da-Cunha M, Hadi F, Balligand T, Stroobant V and Van
            Schaftingen E.
  TITLE     Molecular identification of hydroxylysine kinase and of
            ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and
            phosphoethanolamine
  JOURNAL   J Biol Chem 287 (10), 7246-7255 (2012)
   PUBMED   22241472
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473975.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001072720.1, XM_236254.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00155321,
                              SAMEA5756307 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2504
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..2504
                     /gene="Hykk"
                     /gene_synonym="Agphd1; RGD1308677"
                     /note="hydroxylysine kinase"
                     /db_xref="GeneID:300723"
                     /db_xref="RGD:1308677"
     exon            1..593
                     /gene="Hykk"
                     /gene_synonym="Agphd1; RGD1308677"
                     /inference="alignment:Splign:2.1.0"
     exon            594..944
                     /gene="Hykk"
                     /gene_synonym="Agphd1; RGD1308677"
                     /inference="alignment:Splign:2.1.0"
     CDS             599..1729
                     /gene="Hykk"
                     /gene_synonym="Agphd1; RGD1308677"
                     /EC_number="2.7.1.81"
                     /note="aminoglycoside phosphotransferase domain-containing
                     protein 1; aminoglycoside phosphotransferase domain
                     containing 1"
                     /codon_start=1
                     /product="hydroxylysine kinase"
                     /protein_id="NP_001100293.1"
                     /db_xref="GeneID:300723"
                     /db_xref="RGD:1308677"
                     /translation="MSSGDDQQSQAFTKPTFTEAQASALVESIFGFKVSKIQPLPSYD
                     DQNFHVHISRSQETTDDPVEYVLKISNTKSSQTPDLIEMQNHIIMFLRAAGFPTASVC
                     RTKGDNTISLMSIDSGSEIKSYLVRMLTYLPGRPIAEVATSHQQLYEIGRLAARLDKA
                     LEDFHHPKLNLLHRENFIWNLKNVPLLENYMGALSQSRNREIVEQVIQLFKEEVMTKL
                     SHFRECINHGDLNDHNILVDLSKSASGDAVYQVSGILDFGDMSYGYYVFEVAITIMYM
                     MIESTSPIQVGGHVLAGFESVIPLTAVERDALFLLVCARFSQSLVMATYSCQLYPENK
                     EYLMITAKTGWKHLQQMFDMGKKAVEEIWFETAKSYEAGISM"
     exon            945..1084
                     /gene="Hykk"
                     /gene_synonym="Agphd1; RGD1308677"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1268
                     /gene="Hykk"
                     /gene_synonym="Agphd1; RGD1308677"
                     /inference="alignment:Splign:2.1.0"
     exon            1269..2504
                     /gene="Hykk"
                     /gene_synonym="Agphd1; RGD1308677"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcaaccgatt gctgactgag ggaagagagc cttcggcctc aggaagtctg gtcattgtgc
       61 gtgagaagag cggggaggct gaagcgagac aagcatctct ctgaggggga catccctgag
      121 agagggtggc gggctccggc gacccttgcg ctccccaaac tcgctgcatg cttacggggc
      181 aggtcactgt ccagccacaa ccctgctgag atttcagtgc gcaattttga gggtcccacc
      241 ttcggcgggc ctgcatgcgt gcagggtgga agccattcta agactcccct agacctgaca
      301 cagggctgag aaccggctgt gggccacctc cctcccatcg gtgtctttcg ctccgcagca
      361 agacccactg gaggtgagtc ttgcttccaa tcgcccttgg aagacgacgg tgtagagttc
      421 ctggagcctg tgaactgtga gtggcgccaa ccgttgactt acgaaaataa gtgcagggaa
      481 tatcactgcc tgcttcccaa ccttggaagc tcacagcaga agggttgctg aagacagacc
      541 tggaagaagt gctaaggcag aagttacgag attttgtaac actttaggaa aagacatcat
      601 gtcaagtgga gatgaccagc agtcacaggc ttttaccaag cccactttta ctgaggcaca
      661 agcctctgca ctggtggaat ccatatttgg gttcaaagtg tctaagatcc agccccttcc
      721 cagctatgat gaccaaaact ttcacgttca catttcaaga agccaagaga ctacagatga
      781 cccagttgaa tatgtcctca aaataagcaa cacgaagtct agtcaaactc cagacctgat
      841 tgaaatgcag aaccatatca tcatgtttct gagagcagct ggatttccaa cagcctctgt
      901 gtgccgaact aaaggggata atacgatctc tctcatgtcc attgacagtg gatctgaaat
      961 caaaagctac ctggtcagaa tgctcactta cctcccagga agaccaatcg ctgaggttgc
     1021 caccagccac cagcagttat atgaaatagg aaggctggct gcccgattgg ataaagccct
     1081 ggaggacttc caccatccaa agttaaatct tcttcatcgg gagaacttca tctggaatct
     1141 gaaaaacgtc cctcttctag agaactacat gggtgccctg agccaaagtc gaaaccggga
     1201 gattgttgaa caggtcattc agctgttcaa ggaagaagtg atgaccaaat taagtcattt
     1261 tcgagaatgt attaatcatg gtgaccttaa tgaccataac attttagtag acctcagcaa
     1321 gtcagcctct ggagatgccg tgtatcaagt ctctgggatt ttagacttcg gagacatgag
     1381 ctatggctac tatgtgtttg aagtggccat caccatcatg tacatgatga tcgaaagcac
     1441 aagccctata caagtaggag gtcacgtcct cgcggggttt gaaagtgtga tccccctgac
     1501 cgctgtggag agggatgctt tgttcttact ggtgtgtgcg cgttttagtc agtctcttgt
     1561 catggccaca tactcctgcc agctgtaccc agagaacaaa gagtacctca tgatcacagc
     1621 gaaaaccgga tggaagcatt tacagcagat gtttgacatg ggcaagaaag ccgtagaaga
     1681 aatctggttt gaaactgcca agtcctatga agctgggatc tccatgtgac agatgtggta
     1741 aaaaattaaa gtgctcaaaa ctccctgatg ggtgcacacc cactcatcac tacccactct
     1801 caatgctccg gactcccaag tgaaagacac acactgacag cctaattttt aatatgccct
     1861 aagcaggtca atggctgggc cactccctaa cgccacttgg ctaacacaga ctcccctcca
     1921 atatacctga gttagtactt actaaaatct gtattttgtc tttgctaccc tggaccttgc
     1981 tgggcagccc tcctgggccg cttcccccgt gtacctactt gtcagcaatc gctcccttct
     2041 gcatctttcc gagtggcctg tctcccatgc cctcgttatg gtggcagaat cctctcttcc
     2101 tctctgtccc tctccaggaa tcctaaaagt ccccccgctg tctctctgcc ctggtaattt
     2161 tattggtcac tggtaatttt attgaccagt caaagattgg gacaggattc ctttagtcct
     2221 acctgtggga cactatatac aggtttcgtt tttttttttt tttttgtaac ttaattagaa
     2281 taattacaag ccactacatg tgactgtaga aaagtttgcg ttagctaaaa ctccgttggg
     2341 cctagatcaa atttatgaag gatttttgtg cagagttaaa actgaaatgg tagaacagcc
     2401 actctatgaa ttggcgaggg aagatctagc ttttccagca ctcttaggac cgtcttttac
     2461 acgtaagaaa gtactgcctg gtgaaccctc aacctcagca ctac
//
