LOCUS       XM_039098234           15525 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus Hydin, axonemal central pair apparatus
            protein (Hydin), transcript variant X3, mRNA.
ACCESSION   XM_039098234
VERSION     XM_039098234.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051354.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039098234.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15525
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..15525
                     /gene="Hydin"
                     /note="Hydin, axonemal central pair apparatus protein;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 7 ESTs, 4 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 13 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:292017"
                     /db_xref="RGD:1562254"
     CDS             73..15525
                     /gene="Hydin"
                     /codon_start=1
                     /product="hydrocephalus-inducing protein homolog isoform
                     X3"
                     /protein_id="XP_038954162.1"
                     /db_xref="GeneID:292017"
                     /db_xref="RGD:1562254"
                     /translation="MDTAVHEKVDHKKCRECGQRKYFKPASKRLEEPMGTVHRKMAKV
                     ISGLQSKVLPPMSPKVVTEEEVNRMMSPSEFLKEMSLTTEQKLASTRIICRPQITELL
                     DMGETTHQKFSRVDLDQALFQPFPSEIIFQNYSPCEVYEVPLVLRNNDKIPRMVKVVE
                     ESSPYFKIISPKDIGHKVAPGVPSIFRILFTPEENKDYAHMLTCITEREKFIVPVKAR
                     GARAILDFPDELNFSTCPVKYSTQKVLLVRNIGNKDSMFHLKTRSPYSVEPTGGILNV
                     GESMQLEVNFEPQTVGNHSGKLIVIYDTGEMVFVCLYGAAIDVNIRLDKNSLIMERTY
                     ISLSNQRSITIHNRTNIIAHFQWKVFATQEEEDKEKHREEKQETSMILEDCILDPSLR
                     ERLSIISRTFENQRKLVQGNSMLFLDHIFTIDPLEGDVWPNSTAEITVYFNPLEARLY
                     QQTVYCDISGREIRLPLRIRGEGMGPKIHFNFELLDIGKVFIGSAHCYEAILSNKGSI
                     DALFNVIPKTSALGACFVFNPKEGIIEPSGVQAVQIAFSSTSLGHFEEEFLIDVNGSP
                     EPVKLTIRGCVIGPTFHFNVPALHFGNVSYGFPHTLTCSLNNTSLVSMTFKLRVRGDG
                     EGMSSIPSYSQDSDSKRRSWINTEISTTKPKEFTITPNSGTIRAQGFAAIKVTLCSNT
                     VQKYELALVVDVEGIGEEVLALLITARCVVPKLQLMTTEVDFGRCFLKYPYEKTIQLV
                     NHDDLPGCYKVLPQIYETSPTMLLSSPSPCGVISPHSTVNIPLALETQVTGAHRSTVY
                     ISVFGSQEAPLACHVQSIGEGPVIFIHPTQIDFGNIYVLKDTSRILQLSNQSFIPAEF
                     RARLANKKSLWTVKPSEGSVPAEDDIPLTLTANLNDIVTFKDTVILEIKHSNTYRIPI
                     QATGIGSTIVSDKPFAPELNLGSHFSLDTHYYRFKLTNKGRRVQQLFWMNDDFNPKEK
                     QSKKGSTGSSRRQSKVSQESTDSGNPVFQLHPVRMELYPGQTIDVILEGYSATPKKVK
                     EKLVCQAIVGAQKGKSLLMSVTIICEFIAPVIQLSTRQLIYRLEKKPNMVLEPDYQPL
                     VIKNVTTLPVRMLLSTSGPFFICETDKSLLPATPKPIKLEVDEEKNFLVKFDPSYRHD
                     LNNWVAEEVLSIKYTEHPQVDNLSLRGEVHYPNLCFEVMEVDFGCILNDTEVIRYIMI
                     TNCSPLVVKFRWFFLVDDEENQIRFAPCMKPYSAFLSQMESIPATSVTASSLAAPPMP
                     EYTEMDFSDSIKTILMDDEAGPEETKKPMTSAMVSEAIKYSSAGTERSQSQPDYPECL
                     WVYDPDEMLSIGIEEVFDILPLYGVLRPYSNHQISFTFYGHCDIVARAKALCEVEGGP
                     TYEIILKGEASLVNYSFDTKDINYGLQLFDHITEREITLKNIGKVGFEFKVLTNYRSS
                     PRNLLPGMPLILPLSGFIQSNKEQVLKVYYLPGIPEVFQRNFQIQIAHLVPENITLYG
                     EGIFPRISLDLHRNLRGNEKYQHFLEQAKKNIEKEYSKYETVNHYEVITEEIPEEETA
                     ELSAHLQMEVERLIVQDYALEHQRGISSSTTEDTYFSHRSCRKLAKVQLPEYILDFGY
                     IVLGDVRTHIIKITNTSHFPVSFHAEKHVLHETGFSTELDRVKNLPYCETETFEVRCD
                     PQGANLSVGNKEVILPIKVSGGPTIHICLQATVTIPSMTLSCNKIEFATIQCGQCMVE
                     TIQLSNHLQVPCEWFVYTPKSTNKMDKHIPKYLRRKLRAEMTPKSRIFEIQPTSGVLD
                     PDERANVQVKFMPKEEKFYSQSLMFQIGQSNQKLTLLAQGQGLEPRLEFSPSVLELGP
                     LLPYASGDEAEVIVRNPCSFPIEFYSLEFDQQYLLEEKMLRQLKGYDSYNTLLLPPRN
                     PGEKLPQEVYDYFKEVKKSKEEHMKAKYLENLAQENAEEEEMNTSDQGTASTKRTSLS
                     RGISVTSNMEERHLPTEAKNYPDEDDYEESLEKLTFQTDKMQSTDSHSVEEVGEVESN
                     PVSKAIARHLGIDISAEGRLAKNRKGIAIIVYGTPVSGKTANAISMAKFYNTACLNID
                     SIVLEALSDSNNVLGIRARELCIRAAIEQSMREAEESAQESSVTQNLGAPARLSTENL
                     GRFTSDLTLLTQEYKIPKSMRGSVMLSKGKTESHWSGSQKQQGQQQQQQQQQQPQQQQ
                     QPQQQQQQQHHQHQSETPQISSSPLLGGPTQRRLSVSASIGGETGLMSCVLPDDLLIQ
                     ILAERIQLSDCFRGVVFDGLDTLFARNAPSALICLLKAIGSREHIYVINMSQDYVAMK
                     AQEKAKKELEETKRQEALAKEKERLQTLDEEEYDALTAEQKIAFDREVRQALRERKKR
                     ELERLAREMHEKKLQQELERQKEEDELKRKVKRPKPGPVAKEEPPLKKSQGPTNKQLP
                     SVAKLEMKMESIERKVSVREHGLLEETTRKKKATTEYAFGFPITQEQEESEGDFLKDS
                     DKNLAQKFKVYDTCLKDVQNILMYWDRKQGMMVPHTGPDEIPHEVDDQRQAPSGGGGR
                     KGRKDRERERLEKERAEKERLEREKAERERLEKLRAMEERSDGEGEGEEEHEGKKDLG
                     VPFINIQTPDFEGISWKQALESDKLPKGDQILNILGLGSSGPPIPPPVLFSIISYPAK
                     RQSLVATEILKHFVFVIPPNDDLPLSDEKKDMEGDSDLFLNTIVTKAQEEQPSPPAKG
                     SKQKSKDKTEQARETQKDKRRTYSGRKGLSGGASGNLAPMSDIDQNNFDGEHSQEKFI
                     RLNHFRWIVPPNGEVTLRMHFSSFDVGNYDQTFNFELLGTRRQYQLYCRGVCTYPYIC
                     KDPKIVYPQRKKDMKLKEVVVKKYVVSMDKFYFGPLLCGKSRDKYKSSLYPDNMETLT
                     ILNDSPMVVEAYFCFQHDVKASTYFLEPVNMTLKPNEKQILNVWAYPTAVGVFEDSIV
                     CCIKENPEPAIFKICCQGIRPEIEVEPRQLHFDRLLLHRKESKSLVLRNVTSLPVAWR
                     ISSLEHLGEDFTVSMMQGTMLPKGEFGLQVHFQPSKPVNIKKAIRIEVLDAENLVGVV
                     QIENILIFAESYDIALDITFPKGTEGGLDFGTLRVLEEVKQPLQLKNRGKYEIIFSFT
                     VDSVGILPTNLSSMIWIQPKRGTLASIDKPTTVQVFFRARKEVKVESQPILRCQIIEP
                     ALSEGEIIASIPIKFSVNAVYSKFTISPSSIINFGALICGTRKSITFTIENQGIIDFK
                     YALYRLTGESPILQKKATSHMRHGRTRESESFYKPGAPKMAKFSDIVQKDMNIANQAR
                     FTHGMFTVYPGFGSVSSGGQQVITVECVADPVGRCEEFLAIDISDRDPRENPAGIPYT
                     LLAEACLPAFVTDNNILIFEEHQICTSPNLYHIQQTIQSGGLFVEDENKFIFCNVLVG
                     HKAKARFKISNVGKISCDVNIIVRPISNKVVNRIIDIFDVDPNKMCIGSRSHAFATVL
                     FTPQAMQTYQCIFEATLDGLPSTLARSRGLVFDIIGEGTLPRVTVIRPTLYNQHGNPL
                     LLFKRLLLGHSEKLPLILKNNGTIPAQLHVDLRDQLGVFSLKGRPTTSYIYIMEENKP
                     NEKVKKAHTASLVVSPGDTAEFDVFFHSNKIGRMTGTIHLTVINNQYEETMIHLVGES
                     YEDDITLDNIHGLINTTSQETSEMSEVIEIAEESAMEDLVTAALLDHIQFGYCHIGIS
                     YNVSFTITNHSQANVIRFEWPLLATLSFSPQIGHLHPGCSKDVVVTLKSESPITLKKM
                     CVKCKLSKIMFQLPVDQVPDWDDRMRTVKWVDAPRNTPGNLTTKRKVIETDPEPAHSV
                     VEENYRELRIQFSANVDFASYKCETSEVFFKETLVYQTRVFEFDLVNTGQVLLEFCWI
                     SEEVSKIVSFAMPENPGSSQKDQLSQGTGSSLDSALDHWTEASPSPFSVEPSSGFVPV
                     GKTQKLKLKFSPMDIGEFESSLYCQIPNLPLGEQGPLLITKGRSVLPFCHFDLKESDY
                     ISGHRRNPELRGPGSGPLEPNTRVIEFTSVGIGGKNLRTFTILNPTNSTYSFCWTSEE
                     TESLQNPPAFVCLTEKGIIHPEKKAEIIFQFLPAHLDITEAFWTFSIPEHNISVPFLL
                     VGKTTDPLISLDKSHLNFSSLLIGREARETVKIINKEEQGFNFAFQDSSRYSEGFNNS
                     LIVCPMEGWIPPLSRFPVDIFFTPKQEGDVNFNLICNIKKKAHPLTLNVKAEGYTMNA
                     EVKCRDRMGSTTLLTSTQVNTINFYEVELNECVQCEFNFINTGKFNFSYQAELSGPKF
                     LLQYLDFTPTDNSVDVGQSEPASLSFQPYQKCVLKGLELKIKISHGPTFICNVVGCAV
                     SPAVHFSFTSHNFGTCFIYQAGMPPYKQNLVVTNREETSMSLDCLYTNTPHVEVNFSV
                     DVIKPGKTLEIPITFYPREAINYRELIPFEINGLSQQTVEIKGKGTEMKLLVLDPANR
                     IVKLGAVLPGQVVKKTVSLVNNSLAQLTFNHSIMFSIPELQEAKVITVEPFHSITMKP
                     KEVCKLEITFAPKKRVPPFSEEVFMEWMGLLRPLFLLSGCCQALEISLDQEHLPFGPV
                     VYQTQATRRILMMNTGDVGARFKWDVKKLKPHFTISPEEGYITSGTEIALEVTYHPTE
                     IGKESLYKNILCFIQGGSPLCLTLSGICVGPPVVKEVVNFNCQVRSRHTQTILLSNRS
                     NQTWNLHPIFEGEHWEGPEFITLEAHQQNKPYEITYKPRTMNLENRKHQGTLFFPLPD
                     GTGWLYALHGTAELPKAVANIYREVPCKTPYTELLPISNWLNKPQRFRVIVEILKPEK
                     PDLSVTLKGLDYIDVLSGSKKDYKLNFFAYKEGLYTAKVIFRNEVTNEFLYYTVSFRV
                     TPSGIIKSIQMTSPVRQSVSASIKLENPLPYSVTFSTECKLNDISLPSQFAVPPNSEG
                     TFSFEFQPLKAGEICGRLTLHNGDLGYYQYELLLKALPAPPEKPVHFQTVLGSSQSIL
                     AKFTNYTRLKTEYYCKTDCSDFHTEKIINAAPGAQGGTEVSVEVIFEPSHLGETKGIL
                     CLSSLIGGEYIIPLFGIALPPKPQGPFLIRAGYNIIIPFKNIFLHATNFSFIVENPAF
                     TIRAAESVRPKKINNITVYFEGNPSGSKTPITTKLIVTCPQCEGTESGIKWVYYLKGI
                     TP"
ORIGIN      
        1 tctccaatca acgttgctct tgttagagtg tgagccaccc tagcggttgc tgtggcaaca
       61 gatggtaaca agatggacac agcagtgcac gaaaaagtgg atcacaaaaa atgcagagag
      121 tgtggacaaa ggaaatattt caaaccagca agtaaaaggc ttgaggaacc catggggact
      181 gtgcatcgga agatggccaa agtgatctcc ggactgcaga gcaaagtctt gccacccatg
      241 agcccgaagg tggtcacaga ggaggaagtg aaccggatga tgtcgccctc agaattcctg
      301 aaggagatgt ccctcactac ggagcagaaa ctggcaagta cacgaatcat atgccgacca
      361 cagatcaccg aactcctaga tatgggagaa acaacgcatc aaaagttttc cagagttgac
      421 ttggatcagg ccttgttcca gccctttcca tcagaaatca tattccagaa ctattctccc
      481 tgtgaagtct atgaagtgcc attggttttg aggaacaacg acaaaatccc aaggatggta
      541 aaagttgttg aagaaagctc accttacttt aaaatcatca gccccaaaga catcggccac
      601 aaggtagccc cgggagtgcc gtccatattc cgaatcctct tcactccaga ggagaacaag
      661 gattatgccc acatgctgac ctgtatcacc gaaagagaga agttcattgt gcccgtcaaa
      721 gctagagggg ctcgagccat cctggacttt cccgatgagc tgaatttttc cacttgccct
      781 gtgaaataca gcacccagaa ggttctgctg gtccgcaaca ttggcaacaa agactccatg
      841 ttccacctca aaactcgaag cccttactca gtagagccaa cgggcgggat tcttaacgtg
      901 ggggaatcca tgcaactgga agtgaacttt gagccgcaga ctgtgggcaa tcacagtgga
      961 aaactcatcg tgatttacga cacaggggaa atggtctttg tgtgtctcta tggagctgcc
     1021 atagacgtga atataagact agacaaaaat tctttgatca tggagagaac ctacatatcg
     1081 ctgtccaacc aacggtctat caccatccac aaccgcacta atataattgc ccatttccag
     1141 tggaaggtgt ttgctaccca agaagaagag gacaaagaaa aacataggga ggaaaagcag
     1201 gaaaccagca tgatacttga agactgcatc ttggatccct cgctccgaga acgcctgtcc
     1261 attatctccc gtacgtttga gaaccagagg aagctggttc aaggaaacag catgctcttt
     1321 ctggatcaca ttttcacgat agatcccctg gaaggcgatg tctggcctaa ctcaacagct
     1381 gaaatcactg tgtactttaa ccccctagaa gccaggctct accagcagac ggtttactgt
     1441 gacatctcag gccgagagat ccgcttgccc ctccgaatca gaggagaagg aatggggccc
     1501 aagattcact tcaacttcga attactggac attggcaaag ttttcattgg atctgcccac
     1561 tgctatgagg cgatcctttc caacaaaggc agcatcgatg ccctcttcaa cgtcatcccc
     1621 aaaacttcag ccttgggggc ctgctttgtt ttcaatccta aagaaggcat cattgaaccg
     1681 agtggggtcc aagccgtcca gatcgccttc agttccacca gcctggggca cttcgaagaa
     1741 gagttcctga tcgatgtcaa cgggtcccct gagcccgtga aactgaccat tcgaggctgt
     1801 gtgattggac ctacattcca ttttaatgtc cctgctctgc actttgggaa tgtttcctat
     1861 ggatttcccc atactttgac gtgttccctc aataatacgt ctttggtctc catgaccttc
     1921 aaactgcgtg tccgtggcga tggcgaaggc atgagtagca tcccaagtta ctctcaggat
     1981 tcggacagca aacgacggtc atggattaat acagaaatat ccacaacaaa acccaaagaa
     2041 tttaccatca ctcccaacag tggcaccatc cgtgcccagg gttttgctgc catcaaggtg
     2101 accttgtgct ccaacaccgt gcagaaatac gagctggcgc tggtggtaga tgtggagggc
     2161 atcggagagg aagtgctggc gctcttgatt acagccagat gtgttgtgcc caagctccag
     2221 ttgatgacta cagaggtgga cttcgggcgc tgcttcctga agtacccata cgagaagacc
     2281 atccagcttg tcaaccatga tgaccttcct gggtgctata aggtcctgcc tcagatatat
     2341 gagacttcac ccaccatgct gctttctagc ccctccccct gtggagtcat ctccccccac
     2401 agcactgtaa acataccact agcgttggag acccaggtca ctggtgcaca cagatccacg
     2461 gtttacatct cagtcttcgg gagccaggaa gcccctctgg catgtcacgt acagagtatt
     2521 ggagaagggc ccgttatctt catacacccc actcagatcg acttcggcaa tatctacgtc
     2581 ctgaaggaca cgtccagaat tctccagctc tctaaccagt ccttcatccc tgcagaattc
     2641 cgggctcgcc tggcaaacaa aaagtccctt tggacggtta aacccagtga gggctcagtt
     2701 cctgcagaag atgacatccc actgacgctg actgccaacc tgaatgacat agtgacgttc
     2761 aaagacacgg tcatcctgga gattaagcac agtaacacct accggatccc catccaggcc
     2821 actgggattg gttcgaccat tgtttccgac aaaccgtttg ctccagaact caacttggga
     2881 tcgcatttta gcctggatac ccactattac cgcttcaagc tgaccaacaa aggacggcgg
     2941 gtccagcaac tgttctggat gaatgacgac ttcaacccca aagaaaagca gagtaagaag
     3001 ggctctactg gtagtagccg tcgccagtcc aaggtctccc aggaatccac agatagcggg
     3061 aaccccgtgt ttcaactcca ccctgtcagg atggagttgt acccagggca gacaatcgac
     3121 gtgatactcg aaggctattc cgccacgccc aagaaagtca aagaaaagct ggtgtgccag
     3181 gccatcgtcg gagcccagaa ggggaaaagc ttgttgatgt ctgtgaccat catctgcgag
     3241 tttatagctc cagtgatcca gctatccacc aggcagctca tatatcggct ggaaaagaag
     3301 cctaacatgg tcctggagcc tgactaccag cccctggtga taaagaatgt gaccaccctg
     3361 cctgtgagga tgctgctctc cacctccggg cccttcttca tctgtgaaac tgataaatcc
     3421 ctgctgcctg caactccgaa gcccataaaa ctggaggttg atgaggagaa aaacttcctg
     3481 gtcaagtttg atccgtccta cagacacgac ctgaacaact gggttgcaga agaggttcta
     3541 tccattaagt acacggaaca ccctcaggtg gacaacctga gcttgcgtgg agaagtgcat
     3601 taccccaacc tctgttttga ggtgatggag gtggatttcg gctgcatcct gaatgatacc
     3661 gaggtcattc gctacatcat gatcaccaat tgcagcccct tggttgtgaa attccgctgg
     3721 ttcttcctgg tggatgatga ggaaaatcag atcaggtttg caccatgtat gaagccctac
     3781 agcgccttct tgtcccagat ggagtccatc ccagcaacgt cagtcaccgc tagctctctg
     3841 gcggccccac cgatgccaga gtacactgag atggacttca gtgattctat caagaccatc
     3901 cttatggacg acgaagctgg acctgaagaa accaaaaagc ccatgacgtc cgctatggtc
     3961 tcagaagcaa taaaatacag ctccgcggga acagaaagaa gccagagcca gccggactac
     4021 ccagaatgcc tgtgggtcta tgacccggat gagatgcttt ctattgggat agaagaagtc
     4081 ttcgacattt tgcccctcta cggagttctg cggccctaca gcaaccatca aatatcgttt
     4141 accttctacg gacactgtga catcgtcgcc cgggccaaag ctctgtgtga agtggaagga
     4201 gggcccacct atgaaataat cctgaagggg gaggcgtccc tggtcaacta ctcctttgac
     4261 acgaaggaca ttaactatgg attgcagctg tttgaccata tcacagaacg tgaaatcaca
     4321 ctgaaaaaca tcgggaaagt tggctttgag ttcaaagttc tgactaatta ccggtcttcc
     4381 ccaaggaacc ttctccctgg aatgccactt atcctgcctc tgtcgggttt tatccagtcg
     4441 aataaggagc aggtgctgaa agtttactac ttgcctggaa taccagaagt cttccaaaga
     4501 aacttccaga tacaaatcgc ccacctggtc ccagaaaaca tcactctgta cggagagggc
     4561 atcttcccac gaatcagcct tgacctacac aggaacctcc gaggcaatga aaagtaccaa
     4621 cacttcttag aacaagcgaa gaaaaacata gaaaaagagt acagtaaata cgagactgtc
     4681 aatcactatg aggtgattac agaggaaatc cccgaggagg agaccgcaga gttaagtgct
     4741 catctccaga tggaggtaga acgacttata gtccaagact acgccctgga acaccagaga
     4801 ggcatctcct ccagtaccac agaggacacc tacttcagcc accggagctg ccgcaaacta
     4861 gccaaagtcc agctgccaga gtacatcctg gactttggct acattgtgct tggtgacgtc
     4921 cgaacccaca tcatcaagat caccaacacc agtcactttc ctgtgtcctt ccatgcagaa
     4981 aagcatgtcc ttcatgaaac aggcttcagc actgagctag accgtgtaaa gaacctacct
     5041 tactgtgaga cagaaacatt cgaagtgaga tgtgacccac aaggggctaa tctttctgtg
     5101 ggcaacaaag aagtcattct ccccatcaag gtgtctggag ggccaaccat tcacatctgc
     5161 ctccaagcca ctgtgaccat tccaagtatg accctgtcgt gcaacaaaat agaatttgct
     5221 acaatccagt gtgggcagtg catggtagaa accattcagc tttccaacca tctccaagtc
     5281 ccttgtgaat ggtttgtcta caccccgaag tctactaaca agatggataa acacatacca
     5341 aagtatttaa ggcgaaagct gcgagctgag atgacgccca agtctcggat ctttgagatc
     5401 caacccactt ccggagtctt ggatcctgac gagagggcca acgtgcaagt gaaattcatg
     5461 cctaaagaag agaaattcta cagccaatct ctgatgttcc agattggcca gagcaatcag
     5521 aagcttactc ttctagcgca gggtcaaggt ctggagccac gcctggaatt cagcccttca
     5581 gttctggaac tggggcccct cctgccttat gcatcaggag atgaggccga ggtgattgtg
     5641 aggaaccctt gcagcttccc cattgagttt tactctctag aatttgacca gcagtatctc
     5701 ttagaagaaa agatgctgcg gcagctgaaa ggctatgact cctacaacac tttgctgctg
     5761 cctccccgga acccggggga gaagctgccc caggaagtct acgattactt taaggaggta
     5821 aagaaatcaa aagaggagca catgaaggcc aagtacctgg agaacctggc gcaggagaat
     5881 gcagaagagg aagaaatgaa cacatctgac caaggaaccg ccagcacaaa gaggacatca
     5941 cttagccgag ggatctctgt cacatccaac atggaagagc ggcatcttcc gactgaagcc
     6001 aagaactacc cagatgagga cgactatgaa gaaagcctgg agaaactaac gtttcaaacc
     6061 gacaagatgc agagcacaga cagccactcc gtggaggagg ttggagaagt ggagagcaac
     6121 ccagtgagca aagcaatagc gcgccacctg ggcatcgaca tttctgcaga aggccgcctg
     6181 gccaagaacc ggaaaggaat cgccattatc gtctacggga cgccggtgtc aggaaagaca
     6241 gccaatgcca tcagcatggc caagttctac aacacagcct gcctgaacat tgactccatt
     6301 gtcttagaag ccctgtcaga ctctaacaac gtccttggga tacgggcccg ggaactgtgc
     6361 atccgagctg ccatagagca gtccatgagg gaagccgagg agtcagccca ggagtcttca
     6421 gtgactcaaa accttggggc accagcacga ctaagcactg agaacttggg caggtttacc
     6481 tccgatctca ctctactgac ccaggaatac aaaatcccga agagcatgcg tgggagcgtg
     6541 atgctctcca aaggcaagac ggaaagccac tggtctgggt ctcagaagca gcaggggcag
     6601 cagcagcagc agcagcagca gcaacaacca caacagcagc aacagccaca acagcagcaa
     6661 cagcagcaac atcatcagca ccaatctgaa acaccgcaga tctcctccag ccctctcctc
     6721 ggcggcccca cccagcggcg gctcagcgtc agcgccagta tcggagggga gactgggctg
     6781 atgagctgtg tgctcccaga tgaccttctc attcagatcc tggctgagcg gatacagctg
     6841 agcgactgtt tcagaggtgt ggtgttcgat ggcctagaca cgctctttgc acggaacgca
     6901 ccttctgccc tcatctgcct gctaaaggcc atcggtagcc gggagcacat atatgtcatc
     6961 aacatgtctc aggattatgt ggccatgaaa gcccaggaga aagctaaaaa ggagctagaa
     7021 gagaccaaac gccaggaagc tcttgcgaag gagaaggagc gtctccagac acttgatgag
     7081 gaagagtatg atgccctaac agcagaacag aaaattgcat ttgaccgcga ggttcggcag
     7141 gcactccggg agagaaagaa gagggagcta gaaagactcg ccagggagat gcatgaaaag
     7201 aagctgcagc aggagttgga gaggcagaag gaggaggacg agctaaaacg gaaggtcaaa
     7261 agacctaaac cgggccctgt ggcaaaggag gagccacccc taaagaagtc acaaggaccc
     7321 acaaacaagc agcttccctc tgtcgccaaa ttagaaatga agatggagtc aatcgaaagg
     7381 aaagtttctg tcagagagca tggattactt gaagaaacca ccaggaaaaa gaaagccacg
     7441 accgaatacg cgtttggatt cccaattacc caggaacagg aggagagcga aggagacttc
     7501 ctgaaggact ctgacaagaa cctggcacaa aagtttaaag tctatgacac gtgtctgaag
     7561 gatgtgcaaa acatcctcat gtattgggac cgcaagcaag ggatgatggt acctcacact
     7621 ggcccagatg agatcccaca cgaggttgac gaccagcgcc aggcgccttc agggggcggg
     7681 gggcgcaagg gccgcaagga ccgggagagg gagcgcttgg agaaggagag ggctgagaag
     7741 gagcgcctgg aaagggagaa ggctgagagg gagcgcctgg agaagctgcg ggccatggag
     7801 gagagaagcg atggggaagg ggaaggagaa gaggagcatg agggaaagaa ggatctcggg
     7861 gtgcccttta tcaacatcca gactccggac tttgaaggca taagctggaa gcaagccctg
     7921 gagagtgaca agcttcccaa aggagatcag atcctgaaca tcctaggcct gggatcctca
     7981 ggaccaccca tccctcctcc agtcttgttc tccatcatct cttacccagc gaagcggcag
     8041 tctttggtcg ccactgagat cctgaagcat tttgtgtttg tgattccacc aaatgatgac
     8101 ctccccctgt cggatgagaa aaaagacatg gaaggagact cagatctctt cctcaacacc
     8161 atcgtcacca aggctcagga ggaacagccc tccccacctg ctaagggaag caagcagaaa
     8221 tcgaaagaca aaacagaaca agctcgcgaa actcagaagg ataaacgtcg cacgtattcc
     8281 ggcaggaaag gcctctctgg cggggcatca gggaaccttg ctccgatgtc tgacatagac
     8341 caaaacaact tcgatggaga acactcccag gagaagttca tcaggctgaa tcacttccgg
     8401 tggattgtgc ctccaaatgg agaggtaacc ttgagaatgc acttctcctc tttcgacgtt
     8461 ggaaactatg accaaacatt taattttgag ctccttggga cccgccgtca ataccagctc
     8521 tactgccgtg gggtgtgcac ctacccatac atctgcaaag acccaaaaat tgtgtaccct
     8581 cagaggaaga aggacatgaa gttaaaggaa gtcgtcgtta agaagtatgt agtgagcatg
     8641 gataagtttt actttggccc actgctctgt ggcaagtcaa gagacaagta taagtcatcc
     8701 ttgtaccctg acaacatgga gacactgaca atcctgaatg attccccaat ggtggtagag
     8761 gcatacttct gtttccagca cgacgtaaaa gcgagcacct actttctaga gcccgtcaac
     8821 atgactctga aacccaatga aaagcagatc ctaaatgtat gggcctaccc tactgcagtc
     8881 ggtgtctttg aagacagcat tgtctgctgc atcaaggaga acccagagcc agccatcttt
     8941 aagatatgct gccaaggaat ccgcccagaa attgaagtgg agcccaggca gttacatttt
     9001 gaccggctct tgcttcatag aaaagaatcc aagtcactag ttctccgtaa tgtcacgtct
     9061 cttcctgtgg cctggaggat ctccagcctg gaacacctag gggaggactt cactgtatcc
     9121 atgatgcagg gcactatgct gcctaaggga gagtttgggc tacaagtgca cttccagccc
     9181 tccaaacctg tcaacatcaa gaaggccatt cggattgagg ttttagatgc agagaatctt
     9241 gtgggtgtcg ttcagatcga aaacatcttg atctttgcag aatcctatga tatcgctttg
     9301 gacatcacct tccccaaagg aactgaagga ggtctggact ttgggactct gagggtcctg
     9361 gaggaagtaa agcagcccct tcaactgaag aaccgtggaa aatacgagat catattcagt
     9421 ttcactgtgg actccgtagg cattttgcca acaaacttaa gttccatgat ctggatccaa
     9481 cccaaaaggg ggacactggc ctcaatagat aagcccacga ccgtgcaagt gttcttccga
     9541 gcaagaaagg aagtgaaggt cgagtcccag cccatcctgc gctgccagat tattgagcca
     9601 gctctctcag aaggtgagat cattgccagc atccctatca agttttctgt gaatgcggtg
     9661 tactccaaat tcaccatcag cccctcctcc atcatcaatt ttggggcttt gatctgcggt
     9721 acaaggaaaa gcatcacctt cactatagaa aaccaaggca taatcgactt caaatatgcc
     9781 ctctacaggc tgactgggga gagtccaatt ctccaaaaga aagcgaccag ccacatgagg
     9841 catgggagaa cccgagaaag tgagagcttc tacaagcccg gagcccctaa aatggccaag
     9901 ttctcggaca tagtccagaa agacatgaac atagcaaacc aggcccgctt cacccatggc
     9961 atgttcactg tatacccggg atttggctcc gtttcttccg gaggacaaca ggtcatcact
    10021 gtggagtgtg tggccgatcc tgtggggagg tgtgaggagt ttctggccat cgatatctct
    10081 gaccgagacc ctagagaaaa ccctgccggc atcccttaca ctctgcttgc cgaagcttgt
    10141 ctaccagcct ttgtgaccga caacaacatc ttgatatttg aagaacatca gatctgtacc
    10201 agccccaacc tgtaccacat ccaacagacc atacagagtg gggggctatt cgtggaggat
    10261 gagaacaagt tcatcttctg caatgtcctg gtgggtcata aggccaaggc tcggttcaag
    10321 atcagcaacg tgggaaagat ctcctgtgat gtcaacatta tcgtcaggcc catctccaac
    10381 aaggtagtca accgcatcat tgacatcttt gacgtggatc ccaacaagat gtgcattggg
    10441 agccgctcac atgccttcgc cacagtgttg ttcacaccac aggccatgca gacctaccag
    10501 tgcatcttcg aggccacctt ggatggcctt cccagcaccc tggcaaggag ccgaggtctt
    10561 gtgtttgata ttattggtga ggggaccctc cctcgagtga ctgtcatccg gccaactctc
    10621 tataaccaac acggaaaccc cttgctcctg tttaagaggc ttctgcttgg tcattcagag
    10681 aaactgcctc tcatcctcaa gaacaacggc accatccccg cccagcttca tgtagacctg
    10741 cgagaccaac taggagtctt ctctctgaaa gggagaccca ccacctccta tatctacatc
    10801 atggaggaaa acaaaccgaa tgaaaaagtt aaaaaagccc acacagcctc cctggtggtt
    10861 tctcctggag acacagccga attcgatgtc tttttccact ccaataagat tgggagaatg
    10921 acaggcacca tccacttaac agtgatcaac aaccagtatg aggagaccat gatccacctg
    10981 gttggagaaa gctatgaaga tgacatcacc ttggacaaca tccatgggct gatcaatacc
    11041 actagccagg agacctcgga gatgtctgag gtcatagaga ttgcagagga gagcgccatg
    11101 gaggacttag tgacagccgc cctgctggat cacatccagt ttgggtactg tcacatcgga
    11161 atcagctaca atgtgagctt caccatcacc aatcacagcc aagcgaatgt gattcgcttt
    11221 gagtggcccc ttttagcaac actgtctttc tccccacaga tagggcatct ccaccctggc
    11281 tgttccaagg acgtagtggt gaccttgaag tcagagtcgc ccatcaccct gaagaagatg
    11341 tgtgtgaagt gcaagctttc caagatcatg tttcagctcc ctgtagacca ggtccccgac
    11401 tgggatgacc gcatgcgcac agtcaagtgg gtggatgctc cccgaaatac acctgggaac
    11461 ctgactacaa aacgaaaggt catagagacg gaccccgagc cagcccactc ggtggtagaa
    11521 gaaaattacc gagagttgcg gatccagttc agtgccaacg tggattttgc ttcctataag
    11581 tgtgaaacga gtgaagtgtt ctttaaggaa acactggttt accagacccg agtatttgag
    11641 tttgaccttg ttaacacagg acaggtgctg ttagaattct gctggatctc agaagaagtc
    11701 tccaagatag tcagtttcgc catgccagag aatccaggtt ccagtcaaaa agatcagcta
    11761 agtcagggga cgggcagctc cctagacagt gccctggacc actggactga agcctctcca
    11821 tcacccttct cggtggaacc ctcctcgggc tttgtgcctg taggcaagac tcagaagctc
    11881 aaactgaagt tctccccaat ggacattgga gagttcgaga gctccctgta ctgccaaatt
    11941 cccaacctgc cactcggaga acaaggccct cttctgataa cgaaagggcg gagcgtcctt
    12001 ccattctgcc atttcgacct gaaggaatca gactacatca gtggtcatcg gcgcaaccca
    12061 gagctccgag gaccaggttc tgggcctctc gaacctaaca cccgagtgat cgagttcacc
    12121 agcgtgggca taggcggaaa gaatctcagg accttcacga ttctgaaccc aaccaacagc
    12181 acttactctt tctgctggac ctctgaagag acagagagtc tccagaatcc tccggccttc
    12241 gtgtgtctca cagagaaggg tattatccac cccgagaaga aagctgagat tatattccag
    12301 ttcctgccgg ctcacctgga catcacggaa gcattctgga ctttctctat cccagagcac
    12361 aatatctcag tgcccttcct gctggtgggc aagaccacag accccctcat ctctcttgac
    12421 aaatcacacc tcaacttcag ctctctcctc ataggcagag aagcccgaga gacggtaaag
    12481 atcatcaaca aggaggagca aggattcaat ttcgccttcc aggacagctc ccgctattct
    12541 gaaggattca acaacagcct catcgtctgt cccatggaag gctggatccc accactgtcc
    12601 aggttcccag ttgatatctt cttcacacca aagcaagaag gagatgtgaa ctttaatttg
    12661 atctgcaaca taaaaaagaa agctcaccct ctgacactca acgtcaaggc ggagggctac
    12721 actatgaacg ctgaggtcaa gtgcagagac cggatgggct ccaccaccct cctaacgtcc
    12781 acccaggtca acaccatcaa cttctacgag gtggagttga atgagtgcgt tcagtgtgaa
    12841 ttcaatttca tcaacactgg caagttcaat ttcagctacc aggcagagct ctctgggccc
    12901 aaattcctgt tgcagtattt ggacttcacg cccaccgaca atagtgtaga tgtgggtcag
    12961 tcagaaccag ccagcctgtc tttccaaccg tatcagaagt gtgtcttgaa gggcctggaa
    13021 ctcaaaatca agatcagcca tggcccaaca ttcatatgca acgtcgtagg ctgtgctgtg
    13081 agcccagctg tccatttctc cttcaccagc cacaactttg ggacttgctt catctaccaa
    13141 gctgggatgc ccccatacaa acaaaacctc gtcgtcacca acagggaaga aacatctatg
    13201 agcctagatt gtttatacac caacacccca cacgtcgagg tgaacttcag tgtggatgtg
    13261 ataaagccag ggaagacact ggagatccca atcacctttt acccccggga agctatcaac
    13321 taccgagaac tcatcccctt tgaaatcaat gggctctctc aacagacagt ggagatcaaa
    13381 gggaaaggca cagaaatgaa gcttttagtc ctagatccag ccaacaggat tgtaaagttg
    13441 ggagctgtcc tgccagggca ggtcgtaaag aaaacagttt ccctcgtcaa caatagcctt
    13501 gcccagctca cctttaatca ctcaatcatg ttctccattc cagagctcca ggaagccaag
    13561 gtcatcaccg tggagccctt ccacagtatc accatgaagc ctaaggaagt ctgtaaacta
    13621 gagattacct ttgcccccaa gaagcgagtc cctcctttct ctgaggaagt cttcatggaa
    13681 tggatggggc tactgcgtcc cctcttcctc ctcagtggct gttgtcaggc cctggagatt
    13741 tccctggacc aagaacatct tcccttcggt cctgttgtgt atcagacaca agccacacgg
    13801 cgcattctca tgatgaacac aggcgatgtg ggtgcaaggt ttaaatggga tgtcaagaag
    13861 ctcaagcccc acttcaccat tagccctgaa gaaggttaca tcacctcagg cacagagatt
    13921 gctctagaag taacctacca ccccaccgag atagggaagg agagtctcta taaaaacatt
    13981 ctctgcttca tccaaggagg aagtcctctg tgcctcaccc tgtctggaat ctgcgtggga
    14041 ccacctgtag taaaagaggt ggtgaatttc aactgccaag tgcgctccag gcacacacag
    14101 actatcctgc tctcaaaccg ttccaaccag acctggaacc tgcaccccat ctttgagggt
    14161 gagcactggg aggggcctga gttcatcacc ttggaggccc atcagcaaaa caagccctac
    14221 gagatcacct acaagccccg aaccatgaac ctggagaacc gcaagcacca gggcactcta
    14281 tttttcccac tcccggatgg gactggctgg ctatatgccc tgcatgggac tgccgaactc
    14341 cccaaagctg ttgccaatat ctaccgtgag gttccatgta agactcccta tactgagctc
    14401 ctgcccatca gcaactggct gaacaagccc cagagattcc gagtcattgt ggaaatattg
    14461 aaaccagaga agccagacct aagtgtcact ctgaagggcc ttgactacat tgatgttctg
    14521 tctggctcca agaaagacta caagctgaac ttctttgcct acaaggaggg actgtacacg
    14581 gcaaaggtga tcttccggaa cgaggtgacc aacgagttct tgtactacac tgtgagtttc
    14641 agggtcaccc cttctggcat cataaaatcc atccagatga caagcccagt ccgccagagc
    14701 gtatcagcct ccatcaagtt ggagaacccc ctgccttatt cggtgacctt ctcaacagag
    14761 tgcaagttga atgacatcag cctgccttcc cagtttgctg tacctccaaa ctctgaggga
    14821 acgttctcgt ttgaattcca gcccttgaaa gctggagaaa tctgcgggag actgaccttg
    14881 cacaatggtg acttgggcta ctaccagtat gagctcctgc tgaaggcctt gcctgcaccc
    14941 cctgagaaac ctgtccactt ccagaccgtt cttggcagca gccaaagcat cttagcgaag
    15001 ttcaccaatt atacccggct gaagactgag tactactgca agactgactg ttctgacttc
    15061 cacacagaaa aaattattaa tgcagcccca ggagcccagg gtggcactga agtcagcgtg
    15121 gaagtcatct ttgagcccag ccatctgggt gagaccaaag gcatcctgtg cctgtcgtca
    15181 ctcataggtg gggaatatat catcccactc tttggaattg ctctgccccc caagccccaa
    15241 ggccccttcc tgatcagagc tggatacaac atcatcatcc ccttcaagaa catcttcttg
    15301 catgcaacaa acttctcctt cattgtggag aacccagcct tcaccatccg ggctgcagaa
    15361 tctgtgcggc ccaagaagat caacaacatc acagtctatt ttgaggggaa cccgtcaggc
    15421 agtaaaaccc ctatcaccac taagctgatt gtcacctgcc ctcagtgtga aggcactgaa
    15481 tctggaatca aatgggttta ttatctgaag gggatcacac cttaa
//
