LOCUS       NM_024395               2218 bp    mRNA    linear   ROD 05-OCT-2024
DEFINITION  Rattus norvegicus 5-hydroxytryptamine (serotonin) receptor 5B
            (Htr5b), mRNA.
ACCESSION   NM_024395 XM_001055046 XM_341111
VERSION     NM_024395.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2218)
  AUTHORS   Serrats,J., Raurich,A., Vilaro,M.T., Mengod,G. and Cortes,R.
  TITLE     5-ht5B receptor mRNA in the raphe nuclei: coexpression with
            serotonin transporter
  JOURNAL   Synapse 51 (2), 102-111 (2004)
   PUBMED   14618677
  REMARK    GeneRIF: In the central superior nucleus , the level of
            coexpression of 5-ht(5B) receptor mRNA with serotonin transporter
            mRNA was high in the intermediate portions of the nucleus
REFERENCE   2  (bases 1 to 2218)
  AUTHORS   Szpirer,C., Van Vooren,P., Riviere,M., Scohy,S., Collau,G. and
            Szpirer,J.
  TITLE     Localization of 54 rat genes, and definition of new synteny groups
            conserved in the human and the rat
  JOURNAL   Mamm Genome 11 (9), 729-735 (2000)
   PUBMED   10967130
REFERENCE   3  (bases 1 to 2218)
  AUTHORS   Wisden,W., Parker,E.M., Mahle,C.D., Grisel,D.A., Nowak,H.P.,
            Yocca,F.D., Felder,C.C., Seeburg,P.H. and Voigt,M.M.
  TITLE     Cloning and characterization of the rat 5-HT5B receptor. Evidence
            that the 5-HT5B receptor couples to a G protein in mammalian cell
            membranes
  JOURNAL   FEBS Lett 333 (1-2), 25-31 (1993)
   PUBMED   8224165
REFERENCE   4  (bases 1 to 2218)
  AUTHORS   Erlander,M.G., Lovenberg,T.W., Baron,B.M., de Lecea,L.,
            Danielson,P.E., Racke,M., Slone,A.L., Siegel,B.W., Foye,P.E.,
            Cannon,K. et al.
  TITLE     Two members of a distinct subfamily of 5-hydroxytryptamine
            receptors differentially expressed in rat brain
  JOURNAL   Proc Natl Acad Sci U S A 90 (8), 3452-3456 (1993)
   PUBMED   7682702
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Nov 27, 2020 this sequence version replaced NM_024395.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: L10073.1, SRR22582424.367631.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680422, SAMN06680429
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1076              JAXUCZ010000013.1  35251511-35252586   c
            1077-2218           JAXUCZ010000013.1  35239662-35240803   c
FEATURES             Location/Qualifiers
     source          1..2218
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q11"
     gene            1..2218
                     /gene="Htr5b"
                     /gene_synonym="5Ht5b; REC17"
                     /note="5-hydroxytryptamine (serotonin) receptor 5B"
                     /db_xref="GeneID:79247"
                     /db_xref="RGD:62388"
     exon            1..1076
                     /gene="Htr5b"
                     /gene_synonym="5Ht5b; REC17"
                     /inference="alignment:Splign:2.1.0"
     CDS             300..1412
                     /gene="Htr5b"
                     /gene_synonym="5Ht5b; REC17"
                     /note="MR22; 5-HT-5B; serotonin receptor 5B; 5-HT5B"
                     /codon_start=1
                     /product="5-hydroxytryptamine receptor 5B"
                     /protein_id="NP_077371.1"
                     /db_xref="GeneID:79247"
                     /db_xref="RGD:62388"
                     /translation="MEVSNLSGATPGIAFPPGPESCSDSPSSGRSMGSTPGGLILSGR
                     EPPFSAFTVLVVTLLVLLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVA
                     ALVMPLSLVSELSAGRRWQLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHL
                     QYTLRTRRRASALMIAITWALSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFST
                     CGAFYVPLAVVLFVYWKIYKAAKFRFGRRRRAVVPLPATTQAKEAPQESETVFTARCR
                     ATVAFQTSGDSWREQKEKRAAMMVGILIGVFVLCWIPFFLTELVSPLCACSLPPIWKS
                     IFLWLGYSNSFFNPLIYTAFNKNYNNAFKSLFTKQR"
     exon            1077..2218
                     /gene="Htr5b"
                     /gene_synonym="5Ht5b; REC17"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcccagtgtg caggcatcag tccccagttc tgcaggcggt tggttactct gaagaccaca
       61 aagagactgg gagaggttga tgcgctggac aaagctagac taaggagtct caactggaaa
      121 aaagggtcta cgaaaacctc aaaaaagaag cgcctacagt ttggaaaaag aacaaaggtg
      181 gcgcggctta gacttctttt tgtgttgctg ggctcgcgca gtgcccctcc tgcctcgcca
      241 cctaaccaca gttcatgcaa tcacgggcac atctgccaga gagcccgagt ccctgaacaa
      301 tggaagtctc taacctctca ggcgccaccc ctggcattgc ctttcctccg ggacccgaga
      361 gctgcagtga cagcccaagt tccggcagaa gcatgggatc caccccaggg gggctcatct
      421 tgtccggccg cgagccgccc ttctctgcct tcaccgtact cgtggtaact ctactggtgt
      481 tgctgatcgc tgccactttc ttatggaatc tgctagttct ggtgactatc ctgcgcgtcc
      541 gcgccttcca ccgtgtgcca cataacttgg tagcctcgac cgccgtctcg gacgtcctgg
      601 tggcggctct ggtgatgcca ctgagcctgg tgagcgagtt gtcggctggg cgacgttggc
      661 agctgggcag gagtctgtgc cacgtgtgga tctccttcga cgtgttgtgc tgcacagcca
      721 gcatctggaa cgtggcggcc atcgccctgg atcgctactg gactatcacg cgccacctgc
      781 agtacacgct gcgcacccgg cgccgcgctt cagcacttat gatcgcgatc acctgggcac
      841 tgtccgccct catcgcgctc gccccgctgc tctttggctg gggcgaagcc tacgatgctc
      901 ggctgcagcg ttgccaggtg agccaggagc cttcgtacgc cgtcttctcc acctgcggag
      961 ctttctacgt gcctctggcc gtggtgctct tcgtctactg gaagatatac aaagccgcca
     1021 agtttcgatt cggccgcaga cggcgggcgg tagtgcccct gcccgccacc acgcaggcaa
     1081 aggaagcacc tcaggagtct gagacggtat tcaccgcgcg ttgcagagcg acagtggcct
     1141 tccagacaag tggagactcc tggcgggagc agaaggagaa gcgagccgcc atgatggtgg
     1201 ggatcttgat cggtgtgttt gtgctgtgct ggatcccctt cttcctgacg gagctcgtca
     1261 gcccgctctg cgcctgcagc ctgccaccca tctggaaaag catattcctg tggcttggct
     1321 attcaaattc gttcttcaat cccttaatct acacggcctt taataagaac tacaacaatg
     1381 ccttcaagag cctctttact aagcagagat aagcagggct ggggagataa aaaggaagac
     1441 cggggaagag aaaggggatc tgccgtcctc atttcaccag agacctgggg gcttctcccc
     1501 gccgcccaca cccccctaac gacactccag aaatcacacc gtagggcctg gaatgttgag
     1561 ttctcacgaa ggtagacaac ggtttggcaa atacatccat gccttctacg cgtcgtgaca
     1621 gacattgcta gtgaattgtg ctacatttct gcaccaggca ggaaccccgc caaacccttt
     1681 ccgggtgtat tttaggtatt attgctcatt tgtcagactc cacatgtggc agagttgatt
     1741 tgcttttgcg ttagtactat gtccctcagt gagggtctct tggggctctc ctgagactga
     1801 ctccttgaca tagcctctcc tctacccctt atccatcaga gcactttacc tttcttagcc
     1861 tcacacagga cctccacaag gcaatgattc tcagtttagg aagagatgtc ctcgcctgaa
     1921 gctttgttaa aaagtgttcc acacagacgt cgtcaagatg gctcagtaga gggggttggg
     1981 gatttagctc agtggtagag cccttgccta gggagcgcaa ggccctgggt tcggtcccca
     2041 gctccgaaaa aaagaaccaa aaaaaaaaaa aaaaaaaaga tggctcagta gatgaaggcg
     2101 cctgtcccca agcctggtgg cctgcttttg agatacatgt aatggaagga aataaaatga
     2161 ttgcaagttg tctctgacct ccagatatgt gccatcagcc ctctccccca tgtgcaca
//
