LOCUS       NM_031750                741 bp    mRNA    linear   ROD 04-DEC-2024
DEFINITION  Rattus norvegicus heat shock protein family B (small) member 3
            (Hspb3), mRNA.
ACCESSION   NM_031750
VERSION     NM_031750.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 741)
  AUTHORS   den Engelsman,J., Boros,S., Dankers,P.Y., Kamps,B., Vree
            Egberts,W.T., Bode,C.S., Lane,L.A., Aquilina,J.A., Benesch,J.L.,
            Robinson,C.V., de Jong,W.W. and Boelens,W.C.
  TITLE     The small heat-shock proteins HSPB2 and HSPB3 form well-defined
            heterooligomers in a unique 3 to 1 subunit ratio
  JOURNAL   J Mol Biol 393 (5), 1022-1032 (2009)
   PUBMED   19715703
  REMARK    GeneRIF: Despite the high level of sequence homology within the
            small heat-shock proteins (sHSPs) family the biochemical properties
            of the HSPB2/B3 complex are distinctly different from those of
            other sHSPs.
REFERENCE   2  (bases 1 to 741)
  AUTHORS   Vos,M.J., Kanon,B. and Kampinga,H.H.
  TITLE     HSPB7 is a SC35 speckle resident small heat shock protein
  JOURNAL   Biochim Biophys Acta 1793 (8), 1343-1353 (2009)
   PUBMED   19464326
  REMARK    Erratum:[Biochim Biophys Acta. 2009 Dec;1793(12):1929-30]
REFERENCE   3  (bases 1 to 741)
  AUTHORS   Sugiyama,Y., Suzuki,A., Kishikawa,M., Akutsu,R., Hirose,T.,
            Waye,M.M., Tsui,S.K., Yoshida,S. and Ohno,S.
  TITLE     Muscle develops a specific form of small heat shock protein complex
            composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation
  JOURNAL   J Biol Chem 275 (2), 1095-1104 (2000)
   PUBMED   10625651
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF203374.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AF203374.1, FM110794.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..741
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q14"
     gene            1..741
                     /gene="Hspb3"
                     /note="heat shock protein family B (small) member 3"
                     /db_xref="GeneID:78951"
                     /db_xref="RGD:68345"
     exon            1..715
                     /gene="Hspb3"
                     /inference="alignment:Splign:2.1.0"
     CDS             147..605
                     /gene="Hspb3"
                     /note="heat shock 27kD protein 3; heat shock 27kD protein
                     family, member 3; heat shock 27kDa protein 3; heat shock
                     protein 3; heat shock protein B3"
                     /codon_start=1
                     /product="heat shock protein beta-3"
                     /protein_id="NP_113938.1"
                     /db_xref="GeneID:78951"
                     /db_xref="RGD:68345"
                     /translation="MAKIILRHLIETPVRYQEEFEARGLEDCRLDHALYALPGPTIED
                     LRKARGTPKALAEDSDSAETPPGEGKSRFQILLDVVQFLPEDIIIQTFEGWLLIKAQH
                     GTRMDEHGFISRSFTRQYKLPDGVETKDLSAILCHDGILVVEVKDPLETK"
ORIGIN      
        1 gctggtctga ttcagcccca attaagctgc tgtctgggca ggactgtaaa ggaagctgct
       61 aagactagaa atcgagtccg caggcagcgc caggggctgg acactcacgg aaagggaagc
      121 ggttcaacgc tggagttgcc tctgctatgg caaaaatcat tttgaggcac ctcatcgaga
      181 ccccagtgcg ttatcaggaa gagtttgaag ctcgaggctt agaagactgc agactggatc
      241 atgctctata cgcactgccc gggccaacca tcgaggacct gaggaaagcc agaggcacac
      301 caaaggctct tgcagaggac tcagactccg ccgagacgcc acctggagaa ggcaaatccc
      361 gtttccagat cttgctggat gtggtccagt tcctgcccga ggacatcatc atccagacct
      421 tcgagggctg gctgctgatc aaggcacagc acggaaccag aatggacgaa cacgggttta
      481 tatcacggag tttcaccaga cagtacaaac tgccagatgg agtcgaaacc aaagatttgt
      541 ctgccatcct ctgtcatgat ggaatcttgg tggtggaagt aaaggatcca ttagagacca
      601 agtgaaaact ttttgattcc tgttcatgcc ataggagaaa gaagaaagcc cgggaattct
      661 taaactcttg agagagactg ctgtaacttg tatgaggatt aaaaatgtat ccacaaaaaa
      721 aaaaaaaaaa aaaaaaaaaa a
//
