LOCUS       NM_001009684            1323 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus hydroxysteroid (17-beta) dehydrogenase 13
            (Hsd17b13), mRNA.
ACCESSION   NM_001009684 XM_223159
VERSION     NM_001009684.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1323)
  AUTHORS   Su,W., Wang,Y., Jia,X., Wu,W., Li,L., Tian,X., Li,S., Wang,C.,
            Xu,H., Cao,J., Han,Q., Xu,S., Chen,Y., Zhong,Y., Zhang,X., Liu,P.,
            Gustafsson,J.A. and Guan,Y.
  TITLE     Comparative proteomic study reveals 17beta-HSD13 as a pathogenic
            protein in nonalcoholic fatty liver disease
  JOURNAL   Proc Natl Acad Sci U S A 111 (31), 11437-11442 (2014)
   PUBMED   25028495
REFERENCE   2  (bases 1 to 1323)
  AUTHORS   Horiguchi,Y., Araki,M. and Motojima,K.
  TITLE     17beta-Hydroxysteroid dehydrogenase type 13 is a liver-specific
            lipid droplet-associated protein
  JOURNAL   Biochem Biophys Res Commun 370 (2), 235-238 (2008)
   PUBMED   18359291
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088191.1.
            
            On Jan 13, 2005 this sequence version replaced XM_223159.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088191.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1323
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..1323
                     /gene="Hsd17b13"
                     /note="hydroxysteroid (17-beta) dehydrogenase 13"
                     /db_xref="GeneID:305150"
                     /db_xref="RGD:1359553"
     exon            1..280
                     /gene="Hsd17b13"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..973
                     /gene="Hsd17b13"
                     /EC_number="1.1.1.62"
                     /EC_number="1.1.1.105"
                     /note="17-beta-hydroxysteroid dehydrogenase 13;
                     17-beta-HSD 13; short-chain dehydrogenase/reductase 9;
                     hepatic retinol/retinal dehydrogenase"
                     /codon_start=1
                     /product="17-beta-hydroxysteroid dehydrogenase 13
                     precursor"
                     /protein_id="NP_001009684.1"
                     /db_xref="GeneID:305150"
                     /db_xref="RGD:1359553"
                     /translation="MNLILELLLLVGIIIYSYLESLVKFFIPQRRKSVAGQTVLITGA
                     GHGIGRLTAYEFAKQKSRLVLWDISKHGVEETAAKCRKLGAVVHVFVVDCSNRAEIYK
                     SVDQVKKEVGDIEIVVNNAGAIYPADLLSTKDEEITKTFEVNILGHFWIIKALLPSML
                     RRNSGHIVTVASVCGHRVIPYLIPYCSSKFAAVGFHRALTAELDTLGKTGIKTSCLCP
                     VFVNTGFTKNPSTRLWPVLEPDEVARSLIDGILTNKKMIFVPSYINISLIVEMFFPER
                     VLKAINRIQNIQFEAIVGHRTKRK"
     exon            281..388
                     /gene="Hsd17b13"
                     /inference="alignment:Splign:2.1.0"
     exon            389..520
                     /gene="Hsd17b13"
                     /inference="alignment:Splign:2.1.0"
     exon            521..627
                     /gene="Hsd17b13"
                     /inference="alignment:Splign:2.1.0"
     exon            628..765
                     /gene="Hsd17b13"
                     /inference="alignment:Splign:2.1.0"
     exon            766..882
                     /gene="Hsd17b13"
                     /inference="alignment:Splign:2.1.0"
     exon            883..1297
                     /gene="Hsd17b13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctctgtgga gctccgtgcg ggggcatctg ctaggagaac agagtccaag ggagagagca
       61 gctcagagcc atgaacctca tcctggagct tctcttgctg gtgggcatca tcatctactc
      121 ctacctggag tcactggtaa agttcttcat tccccagaga agaaagtctg tggccggaca
      181 gactgttctc atcacaggag ctggacacgg aataggcagg ctgacggctt atgaatttgc
      241 aaagcagaaa agcagattgg tcctgtggga tattagtaag cacggtgttg aggaaaccgc
      301 agccaaatgc aggaaactgg gggctgtcgt gcacgtgttt gtggtggact gcagcaaccg
      361 ggcagagatt tacaagtctg tggatcaggt aaagaaagaa gttggtgaca tagagattgt
      421 ggtaaacaac gctggggcaa tttatccagc cgaccttctt agcaccaagg atgaggagat
      481 caccaagacc ttcgaggtca acatcctagg acatttttgg atcataaaag cactccttcc
      541 atcgatgctg agaagaaact ctggccacat tgtcacagtg gcttcagtgt gtggccacag
      601 agtgattcct tatctcatcc catattgctc cagcaagttc gctgctgtgg gcttccacag
      661 agcactgact gcagaactgg acaccttggg gaaaaccggt atcaaaacct cctgtctctg
      721 ccctgtgttc gtgaatactg gcttcaccaa aaacccaagt accaggttat ggcctgtgtt
      781 agagccggat gaagttgcaa ggagtctgat cgatgggata cttaccaaca agaaaatgat
      841 cttcgttccg tcctatatca atatctctct aatagtggaa atgttttttc ctgaacgtgt
      901 cttaaaagct ataaaccgta tacagaatat tcagtttgaa gcgattgtgg gccacagaac
      961 caagaggaag taacatcttg cgtgcagaga cgtgtggacg ccaatgacgc gaagccaagt
     1021 ttagagcgga cgcgaggctt tctttcgccc gttttagaag tgttccttgt gtttaaaatg
     1081 taggtttggc cctagtagcc atcgagcaaa cgagagtggt caactgtcct tctggtttct
     1141 tatacttaaa ctctcagccc ctggtattgg gttctggaaa tggagctgta gtaagacaat
     1201 gcctgtcgca cagccgagtg aaaagtcatt tggtgtgttt ttactaaaca gaaatgtggg
     1261 agaaagggta agacaataaa atcttggaca aatgctgaaa aaaaaaaaaa aaaaaaaaaa
     1321 aaa
//
