LOCUS       NM_001191726            2394 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus heparan sulfate 6-O-sulfotransferase 2 (Hs6st2),
            mRNA.
ACCESSION   NM_001191726 XM_228681
VERSION     NM_001191726.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2394)
  AUTHORS   Habuchi,H., Tanaka,M., Habuchi,O., Yoshida,K., Suzuki,H., Ban,K.
            and Kimata,K.
  TITLE     The occurrence of three isoforms of heparan sulfate
            6-O-sulfotransferase having different specificities for hexuronic
            acid adjacent to the targeted N-sulfoglucosamine
  JOURNAL   J Biol Chem 275 (4), 2859-2868 (2000)
   PUBMED   10644753
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Jul 17, 2010 this sequence version replaced XM_228681.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.33139.1,
                                           SRR26360194.1583346.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMN06621351
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-428               JAXUCZ010000021.1  136181727-136182154 c
            429-947             JAXUCZ010000021.1  136180413-136180931 c
            948-980             JAXUCZ010000021.1  135964712-135964744 c
            981-1067            JAXUCZ010000021.1  135926108-135926194 c
            1068-2394           JAXUCZ010000021.1  135889062-135890388 c
FEATURES             Location/Qualifiers
     source          1..2394
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq36"
     gene            1..2394
                     /gene="Hs6st2"
                     /gene_synonym="RGD1563872; RGD1564397"
                     /note="heparan sulfate 6-O-sulfotransferase 2"
                     /db_xref="GeneID:302489"
                     /db_xref="RGD:1564397"
     CDS             1..1983
                     /gene="Hs6st2"
                     /gene_synonym="RGD1563872; RGD1564397"
                     /EC_number="2.8.2.-"
                     /codon_start=1
                     /product="heparan-sulfate 6-O-sulfotransferase 2"
                     /protein_id="NP_001178655.1"
                     /db_xref="GeneID:302489"
                     /db_xref="RGD:1564397"
                     /translation="MALPAFAARALGPPLQPEQGAPARTTCPRRHSRVEAELAASRPG
                     SVAASVRAGPPRGVSLGFNSPPLQDKPPKTFSSLAGALRAPLFALLPRGRRRRMHDLR
                     RRWDLGSLCRALLTRGLAAVGHSLKHVLSAIFSKIFGPLASVGNMDEKSNKLLLALVM
                     LFLFAVIVLQYVCPGTECQLLRLQAFSSPVPDPYRSEDESSARFVPRYNFSRGDLLRK
                     VDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETW
                     LFSRFSTGWSCGLHADWTELTSCVPAVVDGKRDARLRPSRWRIFQILDAASKDRWGSS
                     NFNSGANSPSSTKPRSTTKSGKNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCD
                     GRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPE
                     KQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQYNTTRASSVE
                     INEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQDARRKRQEQRKFLKGRFL
                     QTHFQSQSQSQGQSQGQSQGQSQGPGQNLSQNPNPNPNQNLTQNLSQNLTQSSNPNLT
                     QRENHGSQKQGSGQEQSDSSTSNGTNDYIGSVETWR"
     exon            1..428
                     /gene="Hs6st2"
                     /gene_synonym="RGD1563872; RGD1564397"
                     /inference="alignment:Splign:2.1.0"
     exon            429..947
                     /gene="Hs6st2"
                     /gene_synonym="RGD1563872; RGD1564397"
                     /inference="alignment:Splign:2.1.0"
     exon            948..980
                     /gene="Hs6st2"
                     /gene_synonym="RGD1563872; RGD1564397"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1067
                     /gene="Hs6st2"
                     /gene_synonym="RGD1563872; RGD1564397"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..2394
                     /gene="Hs6st2"
                     /gene_synonym="RGD1563872; RGD1564397"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcactgc ctgcatttgc agcccgggcg cttgggccgc cactgcaacc ggagcaagga
       61 gcgcccgccc gcaccacctg tccccgccgg cattccagag tagaggccga attggcagca
      121 agccggcccg ggtctgtcgc cgcctcagtc cgtgccggcc ctcctagggg tgtgtctctc
      181 ggattcaact ccccgccgct ccaggacaag cccccaaaga cattttcttc cttggcggga
      241 gccttgcgcg ccccgctctt cgcgctgctg cctcgaggcc gccgcaggcg gatgcacgac
      301 ctcaggcgac gctgggacct gggctccctc tgccgggccc tgctcactcg gggcctggca
      361 gctgtgggcc actcgctcaa gcacgtgctc agtgcgatct tctccaagat tttcggtccc
      421 ttggccagcg tcgggaacat ggatgagaaa tctaacaagc tgctgctggc tttggtgatg
      481 ctcttcctat ttgccgtgat cgtcctccaa tacgtgtgcc ccggcacaga atgccagctc
      541 ctccgcctgc aggcgttcag ctccccggtg ccggatccgt accgctcgga ggatgagagt
      601 tccgccaggt ttgtaccccg ctacaatttc agccgtggcg atctcctgcg caaggtagac
      661 ttcgacatca agggcgatga cctgatcgtg ttcctgcaca tccagaagac tgggggcacc
      721 actttcggcc gtcacctggt gcgcaacatc cagctggagc agccatgtga gtgccgcgtg
      781 gggcagaaga aatgcacttg ccaccggccg ggtaagaggg agacctggct cttctccagg
      841 ttctccaccg gctggagctg cgggctgcat gccgactgga cggagctcac cagctgcgtg
      901 cccgcagtgg tggatggcaa gcgcgacgcc aggctgagac cttccaggtg gaggattttt
      961 cagattctag atgcagcaag taaagataga tggggttctt caaacttcaa ctcaggtgcc
     1021 aactctccat cctccacaaa gccccggagc acaacgaaga gtgggaagaa cttccattat
     1081 atcaccatcc tcagagaccc agtgtctcgg tacctgagcg aatggagaca tgtccagagg
     1141 ggagcaacat ggaaagcatc cctgcacgtc tgtgatggaa ggcccccgac ctctgaggaa
     1201 ctgcccagct gctacaccgg tgatgactgg tctggatgcc ctctcaaaga gttcatggac
     1261 tgcccctata atctggccaa caaccgccaa gtccgcatgc tgtctgacct gactctagtg
     1321 ggctgctaca acctctctgt catgcctgaa aagcaaagaa acaaagtcct tttggaaagt
     1381 gccaaatcca atctgaagca catggcattc tttggcctca ctgagtttca gcgcaagacc
     1441 cagtacctgt ttgagaagac cttcaacatg aactttattt cgccgtttac ccagtataat
     1501 accactaggg cctctagtgt tgagatcaat gaggaaatcc aaaagcgtat tgagggactg
     1561 aattttctgg atatggagct gtacagctat gctaaagacc tctttctgca aaggtatcag
     1621 ttcatgaggc agaaagagca tcaggatgcc aggcggaagc gtcaggagca acggaaattt
     1681 ctgaagggaa ggttccttca gacccatttc cagagtcaga gtcagagtca gggtcagagc
     1741 cagggtcaga gccagggtca gagccagggt ccaggtcaga atctgagtca gaatccaaat
     1801 cccaacccaa atcagaacct gactcagaat ctgagtcaga atctgactca gagttcaaat
     1861 cccaatttga cccaaaggga gaaccacgga agtcagaagc agggctcagg ccaggagcag
     1921 agtgatagca gcaccagcaa tggcaccaat gactacatag ggagcgtaga gacatggcgc
     1981 taactggctc tcaatggctt gtgcacactg cttctcaaag catcaccaaa aagatggcgt
     2041 gtatcttaca agatgaaaat gtccaaacac atcctgcttc cttcattttg gaagttcaaa
     2101 agaaaagtgt agacgttgcc tttacagttg ccttttgatt cagtgttcta ctgtgtgtgg
     2161 gtaaaacaaa tctcagtgtg taattaaatt gtctgctttg ggatgaacta cttctgaaat
     2221 ccaagagcca aaccagactc accagaaatt gcagtttaga tattttaaga agttcttaaa
     2281 ttaggtatgg gagacacaaa gaaaacatga aatgtggccg tttaaactta tggctaagaa
     2341 acagacttta aatgattccg gatactctgt taaaacccaa tcttgaaagc accc
//
