LOCUS       NP_001178655             660 aa            linear   ROD 28-APR-2025
DEFINITION  heparan-sulfate 6-O-sulfotransferase 2 [Rattus norvegicus].
ACCESSION   NP_001178655 XP_228681
VERSION     NP_001178655.1
DBSOURCE    REFSEQ: accession NM_001191726.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 660)
  AUTHORS   Habuchi,H., Tanaka,M., Habuchi,O., Yoshida,K., Suzuki,H., Ban,K.
            and Kimata,K.
  TITLE     The occurrence of three isoforms of heparan sulfate
            6-O-sulfotransferase having different specificities for hexuronic
            acid adjacent to the targeted N-sulfoglucosamine
  JOURNAL   J Biol Chem 275 (4), 2859-2868 (2000)
   PUBMED   10644753
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Jul 17, 2010 this sequence version replaced XP_228681.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.33139.1,
                                           SRR26360194.1583346.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMN06621351
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..660
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq36"
     Protein         1..660
                     /product="heparan-sulfate 6-O-sulfotransferase 2"
                     /EC_number="2.8.2.-"
                     /calculated_mol_wt=74383
     Region          225..531
                     /region_name="Sulfotransfer_2"
                     /note="Sulfotransferase family; pfam03567"
                     /db_xref="CDD:427369"
     CDS             1..660
                     /gene="Hs6st2"
                     /gene_synonym="RGD1563872; RGD1564397"
                     /coded_by="NM_001191726.1:1..1983"
                     /db_xref="GeneID:302489"
                     /db_xref="RGD:1564397"
ORIGIN      
        1 malpafaara lgpplqpeqg aparttcprr hsrveaelaa srpgsvaasv ragpprgvsl
       61 gfnspplqdk ppktfsslag alraplfall prgrrrrmhd lrrrwdlgsl cralltrgla
      121 avghslkhvl saifskifgp lasvgnmdek snklllalvm lflfavivlq yvcpgtecql
      181 lrlqafsspv pdpyrsedes sarfvprynf srgdllrkvd fdikgddliv flhiqktggt
      241 tfgrhlvrni qleqpcecrv gqkkctchrp gkretwlfsr fstgwscglh adwteltscv
      301 pavvdgkrda rlrpsrwrif qildaaskdr wgssnfnsga nspsstkprs ttksgknfhy
      361 itilrdpvsr ylsewrhvqr gatwkaslhv cdgrpptsee lpscytgddw sgcplkefmd
      421 cpynlannrq vrmlsdltlv gcynlsvmpe kqrnkvlles aksnlkhmaf fgltefqrkt
      481 qylfektfnm nfispftqyn ttrassvein eeiqkriegl nfldmelysy akdlflqryq
      541 fmrqkehqda rrkrqeqrkf lkgrflqthf qsqsqsqgqs qgqsqgqsqg pgqnlsqnpn
      601 pnpnqnltqn lsqnltqssn pnltqrenhg sqkqgsgqeq sdsstsngtn dyigsvetwr
//
