LOCUS       NM_001106392            3043 bp    mRNA    linear   ROD 15-NOV-2024
DEFINITION  Rattus norvegicus heparan sulfate-glucosamine 3-sulfotransferase 5
            (Hs3st5), transcript variant 3, mRNA.
ACCESSION   NM_001106392 XM_001061473 XM_228219
VERSION     NM_001106392.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3043)
  AUTHORS   Mochizuki,H., Yoshida,K., Gotoh,M., Sugioka,S., Kikuchi,N.,
            Kwon,Y.D., Tawada,A., Maeyama,K., Inaba,N., Hiruma,T., Kimata,K.
            and Narimatsu,H.
  TITLE     Characterization of a heparan sulfate 3-O-sulfotransferase-5, an
            enzyme synthesizing a tetrasulfated disaccharide
  JOURNAL   J Biol Chem 278 (29), 26780-26787 (2003)
   PUBMED   12740361
REFERENCE   2  (bases 1 to 3043)
  AUTHORS   Xia,G., Chen,J., Tiwari,V., Ju,W., Li,J.P., Malmstrom,A., Shukla,D.
            and Liu,J.
  TITLE     Heparan sulfate 3-O-sulfotransferase isoform 5 generates both an
            antithrombin-binding site and an entry receptor for herpes simplex
            virus, type 1
  JOURNAL   J Biol Chem 277 (40), 37912-37919 (2002)
   PUBMED   12138164
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474051.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_228219.2, XM_001061473.1.
FEATURES             Location/Qualifiers
     source          1..3043
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q12"
     gene            1..3043
                     /gene="Hs3st5"
                     /note="heparan sulfate-glucosamine 3-sulfotransferase 5"
                     /db_xref="GeneID:294449"
                     /db_xref="RGD:1306379"
     exon            1..793
                     /gene="Hs3st5"
                     /inference="alignment:Splign:2.1.0"
     exon            794..852
                     /gene="Hs3st5"
                     /inference="alignment:Splign:2.1.0"
     exon            853..1021
                     /gene="Hs3st5"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1127
                     /gene="Hs3st5"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1266
                     /gene="Hs3st5"
                     /inference="alignment:Splign:2.1.0"
     CDS             1160..2200
                     /gene="Hs3st5"
                     /EC_number="2.8.2.23"
                     /note="heparan sulfate (glucosamine) 3-O-sulfotransferase
                     5"
                     /codon_start=1
                     /product="heparan sulfate glucosamine 3-O-sulfotransferase
                     5"
                     /protein_id="NP_001099862.1"
                     /db_xref="GeneID:294449"
                     /db_xref="RGD:1306379"
                     /translation="MLFKQQVWLRQKLLVLGSLAVGSLLYLVARVGSLDRLQPICPVE
                     SRFGAAHNQAELPLRALQFKRGLLHEFRKGNSSKEQVRLHDLVQQLPKAIIIGVRKGG
                     TRALLEMLNLHPAVVKASQEIHFFDNDENYAKGIEWYRKKMPFSYPQQITIEKSPAYF
                     ITEEVPERIYKMNSSIKLLMIVREPTTRAISDYTQVLEGKERKNKTYYKFEKLAIDPN
                     TCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHIVDGDRLITEPLPELQLVEKFLNLP
                     PRISQYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVDPSVVTKLRKFFHPFNQK
                     FYQITGRTLNWP"
     exon            1267..3043
                     /gene="Hs3st5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgggagggtg tggactggca gccactctgc agctggccgc cggggacctg gtccctcccg
       61 cgagccgaag tgatggaggg gaagagatcc tcttagacac acacgcgcgc gcacatcccg
      121 ctgggcacgt ctccgggagg ctgcagccgg ctcaagcgcg ccggggaccg ggcggcggcc
      181 gtgacagcgc gagcggcggg gagtccgcgg tccgcacagc ttggcacggg tcgcgggagg
      241 acgcccggag ggaagatctc tgccgcgctg actgttgctc ttttgaaggc atctcaaagg
      301 accgagcttc ctgacactat aaccgcggac gccagaggct ctgcccctcg cgtgccgggt
      361 ccgggtcggc gccggtgccc gccgcgggag aggagaatgc gagcctcctc ccgcagagct
      421 cctgcggtcc cctttgcagc gctgactccg gctccagcgg ctgccccaga cgtgcccgcg
      481 ccgcgggagc gcgccctgcc gcacctggct ccagcctcct agggaagtgc gcgaaacgct
      541 ccctaaactc cactacttct cttccccacg tccgcttgcc gctctccgcc ccggacaccg
      601 cagccgccgc tgtcgccgcc ccagagtgga agccgggcta ctgtgctgct tgtttgctct
      661 gcccgccggc tcgctcctag ccgagcatcc caaactactg gacaactgcc actgcgatcg
      721 cgggaaccac tcggtgaccc ggcgcgactg gtctaggctt tccgagccca ggctgtcacc
      781 attagggaca acggtgagga cagagtcaga agacccacaa cagacactca ggacatttca
      841 aactctgaaa tgtgataacc aggtcctact ggcttcagac tggtgctttc agttgcccaa
      901 ctgaggatct acaacagcca gctgacacac tctcggacac tagacaagcc attttgtcat
      961 attcttggaa gtctctcctc tgtatgtaca gaacttcctg gattaacatg aagatgtgaa
     1021 ggtgcttaca aaggaggaac gggacaacca ggaagtgaaa cgaggccatg agacaaccac
     1081 tagccagata atcctgtctg gagtaactga ggcgtgtctg aatgtaggct gctgcagtcc
     1141 tgaaggttga tggagggcca tgctattcaa acagcaggtg tggctaagac agaagctcct
     1201 ggtgcttgga agccttgctg ttgggagcct gctgtatcta gttgccagag ttgggagctt
     1261 ggataggctc cagcccattt gcccggttga aagtcgattt ggtgctgccc acaaccaggc
     1321 tgagctccca ctccgagccc tgcagtttaa aagaggctta ctgcatgagt tccggaaggg
     1381 caactcttcc aaggagcagg tacgcctcca tgacctggtc caacagctcc ccaaagccat
     1441 tatcattggg gtgaggaaag gaggcacaag agccctgcta gagatgttga acctccatcc
     1501 agcagtggtc aaagcttccc aagagatcca cttctttgac aatgacgaaa attatgccaa
     1561 gggcattgag tggtacagga aaaagatgcc tttttcctac cctcagcaaa tcacgatcga
     1621 aaagagcccg gcgtatttca tcaccgaaga ggttccagaa aggatttaca agatgaactc
     1681 atccatcaag ctgttgatga ttgtcaggga gccgaccaca agagcgattt ctgattacac
     1741 tcaggtgcta gaggggaagg agaggaagaa caaaacctac tataagtttg aaaagctggc
     1801 catagaccct aatacctgcg aggtgaacac gaaatacaag gcagttagga ccagcatcta
     1861 cacaaaacat ctggagcgct ggttgaagta ctttcccatt gaacagtttc acatcgtgga
     1921 cggggaccgt ctcatcaccg agcctctgcc agaacttcag ctggtggaga aattcttaaa
     1981 ccttcctccg aggataagtc agtacaattt atatttcaat gctaccagag ggttttactg
     2041 tttgcgattt aacattatct ttaataagtg cctggcgggc agcaaggggc gcatccatcc
     2101 agaggtagac ccctccgtcg ttaccaaatt gcgcaaattc tttcatccct ttaatcaaaa
     2161 attttaccag atcactggga ggacattgaa ctggccctaa aataatatag catacaacac
     2221 catgtgttgt atcttgagac gcatggcgtc ccctctacat taaagtatgc actttcccag
     2281 acacagctcc ccaattcatt tttccacgaa tacttgtaca tatgcagtgt gtgaccaaat
     2341 ataagaccaa ttgtttttct actgaaaatt tacaaataaa taattaagaa attgctttct
     2401 acatagttgc atcttttaag ctatttacag aaagaaaagg aaaaagaaga ggtggtggga
     2461 ctggggaaag tgacgtcaga tattgtcaag ttagtcttcc tttgactcag aacttgtcac
     2521 ccgctattta ttgtcagatt taagccaaaa gatgaatgtg tggaaatgta cctctggcta
     2581 cagagcttca ggaagtaaag gattcagttt aatggttcat gtgttttgtt ttgtttttgt
     2641 cctaagctaa cattggctct ttaattcaaa tacttggatt ggtgccagga aaacagaata
     2701 tgctattttc ttatcatttg aaagaatgtc ttagctcata aaattgacat tgttccaaag
     2761 ttcttgtggt gattttgcac tattgtttcc tcctacggac cacggtgtca tttgtagcat
     2821 gtcagtcacg tgctggagaa ccaccacacc cttcacttcc acgttcgttg tgtgtcaaca
     2881 aagaaaaatg acctgtacat atttgtaaat ggtgtaaata cccgtttcac actaagtaat
     2941 tctattttgt aaactgaata tggctattta atttattgtg aaaattaaat ttattgtggt
     3001 atttaaaatg gaatggatta aaaatacacg atgtgcaact ttc
//
