LOCUS       XM_039108489            3011 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus HPS1, biogenesis of lysosomal
            organelles complex 3 subunit 1 (Hps1), transcript variant X3, mRNA.
ACCESSION   XM_039108489
VERSION     XM_039108489.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039108489.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3011
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3011
                     /gene="Hps1"
                     /gene_synonym="Hps"
                     /note="HPS1, biogenesis of lysosomal organelles complex 3
                     subunit 1; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 mRNAs, 45 ESTs, 2 long SRA
                     reads, 5 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 44 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:114638"
                     /db_xref="RGD:69193"
     CDS             437..2557
                     /gene="Hps1"
                     /gene_synonym="Hps"
                     /codon_start=1
                     /product="BLOC-3 complex member HPS1 isoform X1"
                     /protein_id="XP_038964417.1"
                     /db_xref="GeneID:114638"
                     /db_xref="RGD:69193"
                     /translation="MRCVLVATEGAEVLFYWTDEEFEENLRQKFRQSENEEEELPVLE
                     DQLNTLLAPVIISYMTMLEKLSDTYTCFSTENGDHLYVLHLFGECLFIAINGDHSENE
                     GDLRRKLCVLKYLFEVHFGLVTVDSQLIRKELRPPDLEQRAQVWKHFQRLLGTYSRLR
                     EQEQSFAVEAVERLIHAQLCELSIETLERHVVQAVNSSPERGGEEVLHAFLLVHCKLL
                     AFYSSHVASALRPADLLALILLVQDLQPSQGTTEEEEDGNDGPQPFPHRRPMSSQNIP
                     VQQPRSQSTSVPTRSSKETDTDSISLPEEYFTPAPSPGEQSSGSLVWLDGGTPPSDVL
                     QMAEDTFNGLAPHSPELPRPRRIFLDANIKENYCPLVPHTMYCLPLWPGISMVLLTKS
                     PSTPLALILYQLLDGFSLLEKKLKEGQEAGSALRSQPFVGDLRQKMDKFIKNRVGQEI
                     QNAWLEFKSKAFSRSEPGSSWELLQICGKLKRQLCAIYRLNFLATAPSRGGPHLPQHL
                     QSQAQKLMKERLQDWKDFLLVKSWRNVTIVSYLEDFPGLVHFIYVDRTTGQMVAPSLS
                     PSEKMSSELGKGPLAAFVKAKVWALIRLARRYLQKGCTTLLFQEGDFRCSYFLWFEND
                     MGYKLQMIEVPVLSDDSVPIGVLGGDYYRKLLRYYSKSRPSEPVRCYELLTLHLSVIP
                     TDLLVQQANQLARRLGEASRVTLP"
ORIGIN      
        1 tgctagagtg ctaaacagct gtagggcgga gccacgcagt gacgcggtgc taagtggcgc
       61 ggggagaggc tccctcgtag tccctgctcc tcctggagct tcgcagactg tagtccccac
      121 ccctctcacc catcacccac cccgatactg agcagtgtta ggcgggacag gccactgggg
      181 cagtttgctg gggacagtgg gtgcaggata ttttcacagg atggcccttc tcctcagagc
      241 tacctcattt aagagcaaga aataaggaga acaaaaacca gaaactgagg aacaggtggc
      301 agtaaggacc tgaccctctg tgtgccttca tgccttctct gccttaagca cttgcaggcc
      361 caagcatgcc gcgctgttgt ctgctgaact ggtcagagtc tagctcctgg gaagccccgc
      421 tgtgtgcttt gccaagatga ggtgtgtgtt ggtggccact gagggcgcag aggtcctctt
      481 ctactggacg gatgaggaat ttgaggagaa cctccggcag aagttcaggc agtcagagaa
      541 tgaggaagag gagctccctg tgctggagga ccaactcaac accctcctgg ctccggtcat
      601 catctcttac atgacgatgc tggagaagct ctcggacacg tacacctgct tctcaacaga
      661 aaacggcgac cacctgtatg tcctgcatct gtttggagag tgcctgttca tcgccatcaa
      721 tggagaccac agtgagaacg aaggggacct gcggaggaag ctgtgcgtgc tcaagtacct
      781 gtttgaggtg cacttcgggc tggtgactgt ggacagccag ctcatccgga aggagcttcg
      841 tccccctgac ctggaacagc gtgcccaggt gtggaagcac tttcaaagac tgctggggac
      901 ctacagtcgc ctgcgggaac aggagcagag ctttgctgtg gaggctgtgg agcggctcat
      961 tcacgcccag ctctgcgaac tgagcatcga gaccctggag cgacatgtgg ttcaagcggt
     1021 caactccagc cctgagcggg gcggtgagga ggtcctgcat gccttcctgc ttgtgcactg
     1081 taagctgctg gctttctact ccagccatgt tgcgagcgcc ctgcgccctg cagatctcct
     1141 ggccctcatc cttctggttc aggacctcca gccctcccaa ggcaccaccg aggaggagga
     1201 ggatggcaat gacggccctc agcctttccc ccataggaga cccatgagca gccagaacat
     1261 cccagtccag cagccgagga gccagagcac ctcagttccc accaggagtt ccaaggagac
     1321 agacacagac agcatctccc tccctgagga gtacttcacc cctgctcctt ccccgggcga
     1381 gcagagttca ggtagcctcg tctggctgga tggtggcacc ccgcccagcg acgtccttca
     1441 gatggctgag gacaccttca acgggctggc gccacactcc ccagagcttc ccaggcccag
     1501 aaggatcttc ctggatgcca acataaaaga aaactactgt cccttggtgc cccacaccat
     1561 gtactgcctg cccctgtggc cgggcatcag catggtgctg ctgaccaaga gtcccagcac
     1621 cccactggcc ctgatcctgt accaactgct agatggcttc tcgctactgg agaaaaagct
     1681 gaaggaaggt caggaggccg gaagtgccct gcggtcccag ccctttgttg gagacctgcg
     1741 ccagaagatg gacaagttta tcaagaatcg agttgggcag gagattcaga acgcctggct
     1801 ggagttcaaa agcaaagcct tctctagaag cgaaccagga tcgtcctggg agctgcttca
     1861 gatctgtgga aagctgaagc gacagctgtg tgccatctac cggctaaact tcctggccac
     1921 tgcacccagc aggggaggcc cacacctgcc ccagcacctg caaagccaag cccagaaact
     1981 catgaaggag cgacttcagg actggaagga cttcctgttg gtgaagagct ggagaaatgt
     2041 caccatagtg tcctacctgg aggatttccc aggcctggtc cacttcatct atgtggaccg
     2101 tacgacaggg cagatggtgg ctccttctct cagccccagt gaaaaaatgt cttctgagtt
     2161 gggcaagggg cccctggctg ccttcgtcaa agccaaggtc tgggctctga tccgactggc
     2221 acgcaggtac ctgcagaagg gctgcaccac gctgctattc caggaagggg acttccgctg
     2281 ctcctacttc ctgtggttcg agaacgacat gggatacaaa ctgcagatga tagaggtgcc
     2341 tgtcctctcc gatgactcag tccccattgg cgtgctggga ggtgactact acaggaagct
     2401 ccttcgttac tacagcaaga gccgcccctc ggagccggtc aggtgctatg agctgctgac
     2461 actgcacctg tccgtcatcc ccactgacct gctggtgcag caggccaacc agctcgcccg
     2521 gcgcctgggg gaggcctccc gggtgaccct gccctaggcc ttcttgcttg cagacattca
     2581 ccacagctag gcttcttccg gtcccttctc ccatacccca ctgtggactc ctccacacaa
     2641 gctaatgagc aagccttctc tgaagggagg ggtgccacat ttctgtcggc ccccagaacc
     2701 gtgtggtcag agatggcagc agctgctctg gaaaactgcc cctctgggtg cccagcagag
     2761 cggaaggaag tcttagtact caggctgtgt gaggtcaccg ccctcctgcc gtcctgcaca
     2821 gggtagctgt tttcctaccc tgactggaag gtgctccctc tggctggtct acattccagc
     2881 ttggcccctg cccccttgca actgggccag tgctgtctcc tcacatttga accgacaaca
     2941 cctacctcag ggtggtcagg aggattgctg gacatgctca gatgctcaat aaatgttggc
     3001 tcttgtcatt a
//
