LOCUS       NM_001191903             964 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus homeo box D12 (Hoxd12), mRNA.
ACCESSION   NM_001191903 XM_345373
VERSION     NM_001191903.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 964)
  AUTHORS   Sheth,R., Bastida,M.F. and Ros,M.
  TITLE     Hoxd and Gli3 interactions modulate digit number in the amniote
            limb
  JOURNAL   Dev Biol 310 (2), 430-441 (2007)
   PUBMED   17714700
REFERENCE   2  (bases 1 to 964)
  AUTHORS   Wang,L.L., Jin,C.L., Liu,L.Y., Zhang,X., Ji,S.J. and Sun,K.L.
  TITLE     [Analysis of association between 5' HOXD gene and idiopathic
            congenital talipes equinovarus]
  JOURNAL   Zhonghua Yi Xue Yi Chuan Xue Za Zhi 22 (6), 653-656 (2005)
   PUBMED   16331564
REFERENCE   3  (bases 1 to 964)
  AUTHORS   Shen,W.F., Montgomery,J.C., Rozenfeld,S., Moskow,J.J.,
            Lawrence,H.J., Buchberg,A.M. and Largman,C.
  TITLE     AbdB-like Hox proteins stabilize DNA binding by the Meis1
            homeodomain proteins
  JOURNAL   Mol Cell Biol 17 (11), 6448-6458 (1997)
   PUBMED   9343407
REFERENCE   4  (bases 1 to 964)
  AUTHORS   Zakany,J. and Duboule,D.
  TITLE     Synpolydactyly in mice with a targeted deficiency in the HoxD
            complex
  JOURNAL   Nature 384 (6604), 69-71 (1996)
   PUBMED   8900279
REFERENCE   5  (bases 1 to 964)
  AUTHORS   Davis,A.P. and Capecchi,M.R.
  TITLE     A mutational analysis of the 5' HoxD genes: dissection of genetic
            interactions during limb development in the mouse
  JOURNAL   Development 122 (4), 1175-1185 (1996)
   PUBMED   8620844
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Jul 17, 2010 this sequence version replaced XM_345373.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-643               JAXUCZ010000003.1  79985106-79985748
            644-964             JAXUCZ010000003.1  79985907-79986227
FEATURES             Location/Qualifiers
     source          1..964
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q23"
     gene            1..964
                     /gene="Hoxd12"
                     /note="homeo box D12"
                     /db_xref="GeneID:366082"
                     /db_xref="RGD:1309797"
     exon            1..643
                     /gene="Hoxd12"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..882
                     /gene="Hoxd12"
                     /codon_start=1
                     /product="homeobox protein Hox-D12"
                     /protein_id="NP_001178832.1"
                     /db_xref="GeneID:366082"
                     /db_xref="RGD:1309797"
                     /translation="MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGSQLAALPPISY
                     PRSALPWAATPASCTPAQPTTASAFGGFSQPYLTGSGPIGLQSPGTKDGPEDQVKFYT
                     PDAATASEERSRTRPPFAPESSLVHSALKGTKYDFAGVGRAAPGSVTLLQGAPCASNF
                     KEDTKGPLNLNMAVQVAGVASCLRSSLPDGLPWGAAPGRARKKRKPYTKQQIAELENE
                     FLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVQREQALALY"
     exon            644..964
                     /gene="Hoxd12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctctgagcc ggtcctctta ttccgggttg taactaaata ctgttgctga gcacagccga
       61 ggccctttgt tggagatgtg tgagcgcagt ctctacagag ctggctatgt gggctcgctt
      121 ctgaatttac agtcaccgga ctctttctac ttttctaacc tgcgacccaa tggcagccag
      181 ttggccgcac ttccccccat ctcataccct cgcagcgctc tgccctgggc cgctacgccc
      241 gcctcgtgca cccctgcgca gcctaccacc gcctctgcct ttgggggctt ctctcagccg
      301 tacttgaccg gctctgggcc cattggcctg cagtctccag gcaccaaaga cggacccgaa
      361 gaccaggtca agttctatac gcctgatgcg gccactgcat ctgaggaacg cagccggact
      421 aggccgccct tcgcccccga gtctagcctg gttcactcgg ctctcaaagg caccaagtac
      481 gacttcgcgg gtgtgggccg agccgctcca ggctctgtga ccctgctcca gggggccccc
      541 tgcgcctcca acttcaagga agacaccaaa ggcccgctca acttgaacat ggcagtgcaa
      601 gtggccgggg tggcctcgtg cctgcgatct tcgctgcccg acggcctgcc atggggggcg
      661 gccccgggga gggcccgcaa gaagaggaaa ccatacacaa agcaacagat tgcggagctg
      721 gagaatgaat tcctggtcaa tgaattcatc aaccggcaga aacgtaagga attgtccaac
      781 aggctgaacc tcagcgacca gcaggtcaaa atctggttcc agaaccggcg tatgaagaag
      841 aagcgtgtgg tgcagcgcga gcaagcactg gcgctctact agctgcccac ggggctgagg
      901 ccttgccaag cctgcccttt tggaccgagg cctggctgtg gaggaggtgt tggggctgga
      961 gatt
//
