LOCUS       NM_001108116            2734 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus homeo box C5 (Hoxc5), mRNA.
ACCESSION   NM_001108116 XM_235702
VERSION     NM_001108116.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2734)
  AUTHORS   Moon SM, Ahn MY, Kwon SM, Kim SA, Ahn SG and Yoon JH.
  TITLE     Homeobox C5 expression is associated with the progression of
            4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis
  JOURNAL   J Oral Pathol Med 41 (6), 470-476 (2012)
   PUBMED   22385119
  REMARK    GeneRIF: These results indicate that overexpression of HOXC5 is
            correlated with oral carcinogenesis and strongly contributed to the
            development of OSCC. HOXC5 may be a useful biomarker and has an
            emerging therapeutic target of OSCC.
REFERENCE   2  (bases 1 to 2734)
  AUTHORS   McIntyre DC, Rakshit S, Yallowitz AR, Loken L, Jeannotte L,
            Capecchi MR and Wellik DM.
  TITLE     Hox patterning of the vertebrate rib cage
  JOURNAL   Development 134 (16), 2981-2989 (2007)
   PUBMED   17626057
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474035.2.
            
            On Oct 4, 2007 this sequence version replaced XM_235702.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AW530620.1, BF565809.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2734
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..2734
                     /gene="Hoxc5"
                     /note="homeo box C5"
                     /db_xref="GeneID:315341"
                     /db_xref="RGD:1307584"
     exon            1..528
                     /gene="Hoxc5"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..743
                     /gene="Hoxc5"
                     /codon_start=1
                     /product="homeobox protein Hox-C5"
                     /protein_id="NP_001101586.1"
                     /db_xref="GeneID:315341"
                     /db_xref="RGD:1307584"
                     /translation="MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLD
                     LSITFPPPAPSNSLHGVDMAANPRAHPDRPACSAAAAPGHALGRDEAAPLNPGMYSQK
                     AARPALEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQIYPWMTKLHMSHETDGKRSRT
                     SYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKS
                     KEAL"
     exon            529..2734
                     /gene="Hoxc5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccctcaact tcaaagagtc acaaatcacc cttaatcaaa aagggtgcag aaattttttt
       61 gggccctccc cgccatgagc tcctacgtag ccaattcatt ctataagcag agccccaata
      121 tccctgccta taacatgcaa acttgtggga actatggatc ggcctcagag gtgcaggcat
      181 ccaggtactg ctacggcgga ttggacttaa gcatcacttt cccaccgcct gcgccttcca
      241 actctctcca cggggtagac atggctgcca acccccgggc tcaccccgac cgccccgcct
      301 gcagcgctgc ggccgctccg ggacacgctc tgggcagaga cgaagcggct cctctgaacc
      361 ctgggatgta cagtcagaag gcggcccgcc cggcgctgga ggagcgagct aagagcagtg
      421 gggagatcaa agaggagcag gcgcagacag ggcagcctgc cggactgagc cagccaccgg
      481 ccccgccaca gatttacccg tggatgacca aactgcacat gagccacgag acggatggca
      541 agcggtcccg aaccagttac acgcgctacc agaccctgga actcgagaaa gaattccatt
      601 ttaaccgcta cctcactcgc cgcaggcgca tagagatcgc caacaacttg tgtctcaacg
      661 agagacagat caagatctgg ttccagaacc gcaggatgaa gtggaagaaa gattccaaaa
      721 tgaagagcaa agaggctctt tagagcaagc agggagccct cctcagagag caccctggtc
      781 cgctgtggtc cctgcgccct tccttttcgg ttttcctcct tctagatttt gaggcaaagg
      841 ctagagcact ggctcccggc ctcccagaca aaagcgcatt tctttggcat tccgaatccc
      901 catcgaccca gggttctgca ggaccgcctg cactgcctgt cttgcctcag ctcagctgag
      961 caccccaggc ccggggcaca ttcttgtagg gcgggtactg aataagcctc agtctgggtt
     1021 gcctctccca gctctgagcc ctagctcggc taacctgagt taaggtgaga cagactgtaa
     1081 ccccttctcc ccgacctcca cctcaccccc ttctttgttc ctgcctaggc tggccaggct
     1141 gctgaaggct ggttgtgcca ggcagagcct atggccagaa tccggggtgc tttcaactaa
     1201 cctttataac ttctaaactc gtctttgctt attaatgatt tgcatatgaa agagggagat
     1261 aagtgaaagt gggcctgtag ccctggaggt tgtcctatgc tctctaaacc ttccaacccc
     1321 ctccctaaag cccgggatct tccctagcct ggcttgctgc atgcactctc aggttcacag
     1381 tcccagcctg ctagctagct caactattgg ggtctcttgc ctttggaccc tagcaagtgg
     1441 ttctttgaag ctttttgcta tcctatgtat cttgccatga ctttctcacc ttcctgcccc
     1501 cattgcagtt gcccaactat ttattgactc caagtccttc ctgaaactat attttgtcat
     1561 atcaaataaa gccagaaaaa gaacaggact aaagattcaa tgacttctgt ctgtttaggg
     1621 catgcattga gtagatgtgt gtaaataggc tctgagatgt atggggaggc cctgtctcta
     1681 agccacccct ttaaaaatat ttttaagcac gtttaggatc agcaaggata gggaaaaact
     1741 gagtgccttt ttgattcatg gttccaagaa gggcctctgg ggtgaagggg agtacactgg
     1801 agagctcctg tactgttgta ctgtcgtttc cacatgatgt ggggtgtaca aggcacccag
     1861 acttttctat atcttattct catgttggct aaaaagactc gaggcttcta gactttctgt
     1921 agtctgtgct ttatgtcaga gcaaaggaac ttgtggctcc actgacttag attcaggccc
     1981 ttctgggtct aggttatccc tggggttctt ttctggacat ggaagaacgg ctgggtcctc
     2041 agtcttgggc tatgtttgat ctcagaggat tctcagcaat cgtaggcagt acttggtaaa
     2101 ggggttttgg agaagaggag ttgaccttgg tttgagatgt tcttcagctt tctaagacat
     2161 gggatggggc aagggggact agggggacac tgaatgcaac ctgcagtgtg tgcttgcctt
     2221 agagaaaaca tacaaactgc tccctgtctt ctaaggtcta agccaatgca gggcagttaa
     2281 ctggagtaag agcggtgtag accagggcag gatccatgcc tatttgtcat ctatcacagt
     2341 ctctgagatt ttgtataaat ggggagggtg gctgatagga gaggggacac agctaattca
     2401 cagggggcgg ggctggccta ggctcatgct cttgccagct ccactccagg gtccacgaga
     2461 tggaggaggg agtactttac aggagaaaca aatgcggtgt aggtccataa aactttactg
     2521 cacttcctct ccagcttccc acaatggggt gatttcctgg agccaagcct aggcccccca
     2581 ccctggagga gtggggatct gaagccgggc taaaggctgc tctacactag gacagaaaga
     2641 gaacagagta actctgagga ggggcaggga gatttctttt tatgattatt aatgtttatg
     2701 ctctttggat ttattgaagg tctgacttca ctgc
//
