LOCUS       NM_001308639            1962 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus homeobox C11 (Hoxc11), mRNA.
ACCESSION   NM_001308639 XM_003750413 XM_003754359
VERSION     NM_001308639.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1962)
  AUTHORS   Koyama,E., Yasuda,T., Minugh-Purvis,N., Kinumatsu,T.,
            Yallowitz,A.R., Wellik,D.M. and Pacifici,M.
  TITLE     Hox11 genes establish synovial joint organization and phylogenetic
            characteristics in developing mouse zeugopod skeletal elements
  JOURNAL   Development 137 (22), 3795-3800 (2010)
   PUBMED   20978074
REFERENCE   2  (bases 1 to 1962)
  AUTHORS   Wellik,D.M. and Capecchi,M.R.
  TITLE     Hox10 and Hox11 genes are required to globally pattern the
            mammalian skeleton
  JOURNAL   Science 301 (5631), 363-367 (2003)
   PUBMED   12869760
REFERENCE   3  (bases 1 to 1962)
  AUTHORS   Wellik,D.M., Hawkes,P.J. and Capecchi,M.R.
  TITLE     Hox11 paralogous genes are essential for metanephric kidney
            induction
  JOURNAL   Genes Dev 16 (11), 1423-1432 (2002)
   PUBMED   12050119
REFERENCE   4  (bases 1 to 1962)
  AUTHORS   Mitchelmore,C., Troelsen,J.T., Sjostrom,H. and Noren,O.
  TITLE     The HOXC11 homeodomain protein interacts with the lactase-phlorizin
            hydrolase promoter and stimulates HNF1alpha-dependent transcription
  JOURNAL   J Biol Chem 273 (21), 13297-13306 (1998)
   PUBMED   9582375
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Mar 8, 2022 this sequence version replaced NM_001308639.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760386,
                              SAMEA5760475 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-729               JAXUCZ010000007.1  135969989-135970717
            730-1962            JAXUCZ010000007.1  135971990-135973222
FEATURES             Location/Qualifiers
     source          1..1962
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..1962
                     /gene="Hoxc11"
                     /gene_synonym="RGD1305450"
                     /note="homeobox C11"
                     /db_xref="GeneID:100911859"
                     /db_xref="RGD:6489991"
     exon            1..729
                     /gene="Hoxc11"
                     /gene_synonym="RGD1305450"
                     /inference="alignment:Splign:2.1.0"
     CDS             48..962
                     /gene="Hoxc11"
                     /gene_synonym="RGD1305450"
                     /note="homeobox protein Hox-C11-like"
                     /codon_start=1
                     /product="homeobox protein Hox-C11"
                     /protein_id="NP_001295568.1"
                     /db_xref="GeneID:100911859"
                     /db_xref="RGD:6489991"
                     /translation="MFNSVNLGNFCSPSRKERGADFGERGSCTSNLYLPSCTYYVPEF
                     STVSSFLPQAPSRQISYPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHR
                     ECLPPSTVTEILMKNEGSYGGHHHPSAPHAAPAGFYSSVNKNSVLPQAFDRFFDNAYC
                     GGGDAPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEAEEENTNPSSSGSSHSAT
                     KEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQV
                     KIWFQNRRMKEKKLSRDRLQYFSGNPLL"
     exon            730..1962
                     /gene="Hoxc11"
                     /gene_synonym="RGD1305450"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agatcgggtc caaaacctcc agccggagga ggcaggagaa gagaacgatg tttaactcgg
       61 tcaacctggg caacttctgc tcgccttcgc gcaaggagag gggcgctgac ttcggcgagc
      121 gagggagctg cacctccaac ctctatctgc ccagttgcac ttactacgtg cccgagttct
      181 ccaccgtctc ctccttcctg ccccaggccc cctctcgtca gatttcttat ccctactcag
      241 cccaagtgcc cccggtccgg gaggtctcct acggcctgga accgtccggg aagtggcacc
      301 atcggaacag ctactcgtct tgttatgcgg cggccgacga gcttatgcac cgggagtgcc
      361 tgcctccttc cacagtcact gagatcctca tgaaaaatga aggctcctac ggcggccacc
      421 accaccccag cgccccgcac gcggcacccg ccggtttcta ctcctcagtg aacaagaaca
      481 gcgtcttgcc ccaagccttc gaccgcttct tcgacaacgc ctactgcggt ggcggagatg
      541 cacccgccga gcccccctgc tccggcaagg gcgaggccaa gggggagcct gaggcgcccc
      601 ccgcctcggg acttgcgtcc cgggcagagg ccggtgctga ggccgaggcc gaggaggaga
      661 acacgaatcc cagctcgtcc ggttcttccc attcggcgac caaggagccg gccaagggag
      721 ccgcccccaa cgccccccga acccgcaaga agcgctgccc ttattcgaaa ttccagatcc
      781 gggaactgga gcgagagttt ttcttcaacg tgtacatcaa caaagagaag cggctgcagc
      841 tgtcccgcat gctgaacctg acagaccgac aagtgaaaat ttggtttcag aacagaagaa
      901 tgaaagaaaa aaaactgagc agagaccggc tgcagtattt ttcaggaaat ccgctgctgt
      961 aactgcagac ttgacccttt ggggtgggag ggagggaaag cgggaaattt attttatttt
     1021 attttatttt taattttcta actctttttt ttccgcgggt ggaaaactgg actgtggcca
     1081 gggctggccc cccactgccg ttactggcac ttccttctag aacttccttg gcctcgagtc
     1141 taattcactg taggggacag agacccggcc tggaaaaagg ggtgagggaa gtgtctgacc
     1201 cgtggttagt ggaccctgtt ggcgccaagg ccccaagact gtttatttaa aagaaaatac
     1261 accttgcaac aaaaccttgc tgctccgatt cggtgagagg aggggcgggc acagtgggcg
     1321 ccagagccga acaatccttg aactcaagct ttccctagcc caagtgaaaa gatccactga
     1381 gccaccttgt ctgcgagacc tcccaggctc cccgccccca ccctaccatg cccctcggtt
     1441 aggggccagc taaatgtgat cctgccttgc tgtgaaattc ctgtacgttt gacctggtgt
     1501 taggtgtgca aagtccaagt cctacctccg tctgcgcctg gccccgcctg agcctagctg
     1561 ttctcaccct aaatatgtag acccttcttt tgaaaactcc tacctggtgc gttgagttgt
     1621 ctgaaccttt ccctaggaag tgtcttgccc ccacccctga ggatttattg ctagtctatg
     1681 cagttcttac ctcttttaaa aagaaacagg attgaggtag aaggggtatg ggaagatggg
     1741 gttggacacc tccctctagc tggggtctgc gtttatgtaa atatttttca taagcctctc
     1801 tacctggaga ggaaggggga ggttgagctg gagtgagatt ctaatcactc atccatgtgc
     1861 gtgagtgcgt gtgtatgtgt gcaatcccca ccctacttct gtctctgagg gattgtgtga
     1921 atttttttgg tggcaaataa agatatttca ctctgttcaa ta
//
