LOCUS       NM_001100497             937 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus homeo box B9 (Hoxb9), mRNA.
ACCESSION   NM_001100497 XM_220887
VERSION     NM_001100497.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 937)
  AUTHORS   Nguyen,D.X., Chiang,A.C., Zhang,X.H., Kim,J.Y., Kris,M.G.,
            Ladanyi,M., Gerald,W.L. and Massague,J.
  TITLE     WNT/TCF signaling through LEF1 and HOXB9 mediates lung
            adenocarcinoma metastasis
  JOURNAL   Cell 138 (1), 51-62 (2009)
   PUBMED   19576624
REFERENCE   2  (bases 1 to 937)
  AUTHORS   Wassef,M.A., Chomette,D., Pouilhe,M., Stedman,A., Havis,E.,
            Desmarquet-Trin Dinh,C., Schneider-Maunoury,S.,
            Gilardi-Hebenstreit,P., Charnay,P. and Ghislain,J.
  TITLE     Rostral hindbrain patterning involves the direct activation of a
            Krox20 transcriptional enhancer by Hox/Pbx and Meis factors
  JOURNAL   Development 135 (20), 3369-3378 (2008)
   PUBMED   18787068
REFERENCE   3  (bases 1 to 937)
  AUTHORS   McIntyre,D.C., Rakshit,S., Yallowitz,A.R., Loken,L., Jeannotte,L.,
            Capecchi,M.R. and Wellik,D.M.
  TITLE     Hox patterning of the vertebrate rib cage
  JOURNAL   Development 134 (16), 2981-2989 (2007)
   PUBMED   17626057
REFERENCE   4  (bases 1 to 937)
  AUTHORS   Medina-Martinez,O., Bradley,A. and Ramirez-Solis,R.
  TITLE     A large targeted deletion of Hoxb1-Hoxb9 produces a series of
            single-segment anterior homeotic transformations
  JOURNAL   Dev Biol 222 (1), 71-83 (2000)
   PUBMED   10885747
REFERENCE   5  (bases 1 to 937)
  AUTHORS   Chen,F. and Capecchi,M.R.
  TITLE     Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function
            together to control development of the mammary gland in response to
            pregnancy
  JOURNAL   Proc Natl Acad Sci U S A 96 (2), 541-546 (1999)
   PUBMED   9892669
REFERENCE   6  (bases 1 to 937)
  AUTHORS   Shen,W.F., Rozenfeld,S., Lawrence,H.J. and Largman,C.
  TITLE     The Abd-B-like Hox homeodomain proteins can be subdivided by the
            ability to form complexes with Pbx1a on a novel DNA target
  JOURNAL   J Biol Chem 272 (13), 8198-8206 (1997)
   PUBMED   9079637
REFERENCE   7  (bases 1 to 937)
  AUTHORS   Chen,F. and Capecchi,M.R.
  TITLE     Targeted mutations in hoxa-9 and hoxb-9 reveal synergistic
            interactions
  JOURNAL   Dev Biol 181 (2), 186-196 (1997)
   PUBMED   9013929
REFERENCE   8  (bases 1 to 937)
  AUTHORS   Iimura,T., Oida,S., Takeda,K., Maruoka,Y. and Sasaki,S.
  TITLE     Changes in homeobox-containing gene expression during ectopic bone
            formation induced by bone morphogenetic protein
  JOURNAL   Biochem Biophys Res Commun 201 (2), 980-987 (1994)
   PUBMED   7911662
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Aug 5, 2007 this sequence version replaced XM_220887.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK481201.1, SRR26643287.25447.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN06680412
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-517               JAXUCZ010000010.1  81733857-81734373
            518-937             JAXUCZ010000010.1  81736944-81737363
FEATURES             Location/Qualifiers
     source          1..937
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..937
                     /gene="Hoxb9"
                     /note="homeo box B9"
                     /db_xref="GeneID:287647"
                     /db_xref="RGD:1306158"
     CDS             1..753
                     /gene="Hoxb9"
                     /codon_start=1
                     /product="homeobox protein Hox-B9"
                     /protein_id="NP_001093967.1"
                     /db_xref="GeneID:287647"
                     /db_xref="RGD:1306158"
                     /translation="MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYANPRQPGHAEH
                     LDFPSCSFQPKAPVFGASWAPLSPHASGSLPSVYHPYLQPQGAPAAESRYLRTWLEPA
                     PRAEAAPGQGQAAVKAEPLLGAPGELLKQGTPEYSLETSAGREAVLSNQRAGYGDNKI
                     CEGSEDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEV
                     ARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE"
     exon            1..517
                     /gene="Hoxb9"
                     /inference="alignment:Splign:2.1.0"
     exon            518..937
                     /gene="Hoxb9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtccattt ctgggacgct tagcagctat tatgtcgact cgatcataag tcacgagagc
       61 gaggacgcgc ctccagccaa gtttccttcg ggccagtacg cgaacccgcg gcagccgggc
      121 cacgccgagc acctggactt cccctcgtgc agcttccagc ccaaagctcc ggtgttcggc
      181 gcctcctggg cgccgctgag cccgcacgct tcggggagcc tgccgtcggt ctaccacccc
      241 tacctgcagc cccagggcgc gccggcggcc gagagcaggt acctccgtac ctggctagag
      301 ccggctcccc gcgccgaggc cgccccgggg cagggccagg cggccgtgaa ggcggagccg
      361 ctgctgggcg cgcccgggga gctgcttaaa cagggcacgc ccgagtacag tttggaaact
      421 tcggcgggca gggaggctgt cctgtctaat caaagagccg gctacgggga caataaaatt
      481 tgcgaaggaa gcgaggacaa agagaggccg gatcaaacca acccctctgc caactggctg
      541 cacgcccgct cttcccggaa aaagcgctgt ccctacacca aataccagac gctggagcta
      601 gagaaggagt ttctattcaa tatgtacctc accagggacc gcaggcacga agtggccaga
      661 ctcctcaatc tgagtgagag acaagtcaaa atctggtttc agaaccggcg gatgaaaatg
      721 aagaagatga ataaggagca gggcaaagag taaagatgac cccacctctc cccagctcac
      781 tcttactatt tatgtgttgg ctggaaaagc cactgctgtc tgggttgtac ccaagtgagt
      841 ggggaagggt atctcctctt taaagcccct catctgcacc tggagcccgg ctcctctcct
      901 ttgcctctct ctctctctct ctctctctct ctctctc
//
