LOCUS       NM_001276434            1961 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus high mobility group nucleosome binding domain 5
            (Hmgn5), mRNA.
ACCESSION   NM_001276434 XM_003752094 XM_003754800
VERSION     NM_001276434.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1961)
  AUTHORS   Ciappio,E.D., Krausz,K.W., Rochman,M., Furusawa,T., Bonzo,J.A.,
            Tessarollo,L., Gonzalez,F.J. and Bustin,M.
  TITLE     Metabolomics reveals a role for the chromatin-binding protein HMGN5
            in glutathione metabolism
  JOURNAL   PLoS One 9 (1), e84583 (2014)
   PUBMED   24392144
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1961)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 1961)
  AUTHORS   Rochman,M., Taher,L., Kurahashi,T., Cherukuri,S., Uversky,V.N.,
            Landsman,D., Ovcharenko,I. and Bustin,M.
  TITLE     Effects of HMGN variants on the cellular transcription profile
  JOURNAL   Nucleic Acids Res 39 (10), 4076-4087 (2011)
   PUBMED   21278158
REFERENCE   4  (bases 1 to 1961)
  AUTHORS   Jiang,N., Zhou,L.Q. and Zhang,X.Y.
  TITLE     Downregulation of the nucleosome-binding protein 1 (NSBP1) gene can
            inhibit the in vitro and in vivo proliferation of prostate cancer
            cells
  JOURNAL   Asian J Androl 12 (5), 709-717 (2010)
   PUBMED   20531280
REFERENCE   5  (bases 1 to 1961)
  AUTHORS   Shirakawa,H., Rochman,M., Furusawa,T., Kuehn,M.R., Horigome,S.,
            Haketa,K., Sugita,Y., Inada,T., Komai,M. and Bustin,M.
  TITLE     The nucleosomal binding protein NSBP1 is highly expressed in the
            placenta and modulates the expression of differentiation markers in
            placental Rcho-1 cells
  JOURNAL   J Cell Biochem 106 (4), 651-658 (2009)
   PUBMED   19160411
REFERENCE   6  (bases 1 to 1961)
  AUTHORS   Shirakawa,H., Landsman,D., Postnikov,Y.V. and Bustin,M.
  TITLE     NBP-45, a novel nucleosomal binding protein with a tissue-specific
            and developmentally regulated expression
  JOURNAL   J Biol Chem 275 (9), 6368-6374 (2000)
   PUBMED   10692437
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On or before Feb 22, 2013 this sequence version replaced
            XM_003754800.1, XM_003752094.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760389
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on computational evidence
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-193               JAXUCZ010000021.1  78169815-78170007   c
            194-217             JAXUCZ010000021.1  78168041-78168064   c
            218-247             JAXUCZ010000021.1  78167465-78167494   c
            248-301             JAXUCZ010000021.1  78167161-78167214   c
            302-436             JAXUCZ010000021.1  78164894-78165028   c
            437-1208            JAXUCZ010000021.1  78162273-78163044   c
            1209-1961           JAXUCZ010000021.1  78161439-78162191   c
FEATURES             Location/Qualifiers
     source          1..1961
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq22"
     gene            1..1961
                     /gene="Hmgn5"
                     /gene_synonym="Nsbp1"
                     /note="high mobility group nucleosome binding domain 5"
                     /db_xref="GeneID:100910616"
                     /db_xref="RGD:6497694"
     exon            1..193
                     /gene="Hmgn5"
                     /gene_synonym="Nsbp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..1387
                     /gene="Hmgn5"
                     /gene_synonym="Nsbp1"
                     /note="nucleosome-binding protein 1"
                     /codon_start=1
                     /product="high mobility group nucleosome-binding
                     domain-containing protein 5"
                     /protein_id="NP_001263363.1"
                     /db_xref="GeneID:100910616"
                     /db_xref="RGD:6497694"
                     /translation="MPKRKAAGDASQEPKRRSARLSAMPVPFTPELKPKRASTSRKTK
                     TTNVVEESKDAGATTIPETKPEVVKGECNMENAENGEAKIIEAPISKMETEEVKEQIN
                     EDTEGDGGEKKEAVVTKGKNDELEANIQDVEKDEDEKEHEDTGEEGEDGEREGGLKEK
                     PDVAEIEDAKEAKDDEEKEDKEKEDDKGGDGKKEEEKDDEGEAETEEEVKEQQKEETE
                     GDDGKCKVEENKEGRKESQHEEEGKEELHEEDGKEDLHEEDGKEDLHEEDGKEDLHEE
                     EGKEDLHEEEGKEDLHEEEGKEDLHEEEGKEDLHEEEGKEDLHEEEGKEDLHEEEGKE
                     DLHEEDGKEGQHEEDGKKKADGNEDRKEEEEQEAATEGNDENKVEVEEEADNKDFKED
                     GEKGEPVSTV"
     exon            194..217
                     /gene="Hmgn5"
                     /gene_synonym="Nsbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            218..247
                     /gene="Hmgn5"
                     /gene_synonym="Nsbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            248..301
                     /gene="Hmgn5"
                     /gene_synonym="Nsbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            302..436
                     /gene="Hmgn5"
                     /gene_synonym="Nsbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            437..1208
                     /gene="Hmgn5"
                     /gene_synonym="Nsbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1961
                     /gene="Hmgn5"
                     /gene_synonym="Nsbp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgtgttta atgttgccaa taacgagaga ttttttttta gggggagggg ggacgcgagt
       61 acatatcgtg ctgcaattag ttcattgaaa actcagtcgc tcgcggagca gtcaggcaga
      121 gactcctctc ggcttttttt ccctcctgcc taaggatctc ctacggagag ctgcaacaat
      181 gcccaaaaga aaggctgcag gtgatgcgag ccaggagcca aagagaagat cggctcgact
      241 gtctgctatg cctgtgccct ttacaccgga gttgaaacct aaaagagcat caacttcaag
      301 gaaaacgaag accacaaatg tcgtggaaga aagcaaagat gcaggtgcca caacaattcc
      361 tgaaaccaag ccagaagttg ttaaaggaga atgcaacatg gaaaatgctg aaaatggaga
      421 agccaaaatt attgaggcac ccatttctaa aatggaaact gaggaagtaa aagaacagat
      481 aaatgaagac actgaaggag atggaggaga aaagaaagaa gcagtggtaa caaaaggcaa
      541 aaatgatgag ctagaagcaa acattcaaga tgtggagaaa gatgaagatg aaaaagagca
      601 cgaagataca ggtgaggagg gagaagatgg ggaaagggaa ggaggcctaa aagagaaacc
      661 agatgtagct gaaatcgaag acgcaaagga ggccaaagat gatgaagaga aggaagacaa
      721 ggaaaaagaa gatgacaaag gaggtgatgg gaagaaggaa gaagagaaag atgatgaggg
      781 ggaagctgaa acagaggaag aagtaaaaga acaacagaaa gaggaaactg agggggatga
      841 tgggaaatgc aaagtagagg aaaacaagga aggcagaaag gaaagtcagc atgaggaaga
      901 aggaaaggaa gagctgcatg aggaagacgg aaaggaagat ctgcatgagg aagacggaaa
      961 ggaagatctg catgaggaag acggaaagga agatctgcat gaggaagaag ggaaggaaga
     1021 tctgcatgag gaagaaggga aggaagatct gcatgaggaa gaagggaagg aagatctgca
     1081 tgaggaagaa gggaaggaag atctgcatga ggaagagggg aaggaagatc tgcatgagga
     1141 agaagggaag gaagatctgc atgaggaaga agggaaggaa gatctgcatg aggaagacgg
     1201 aaaggaaggt cagcatgagg aagacggaaa aaagaaggct gacggaaacg aggatagaaa
     1261 ggaagaagaa gagcaagagg ctgctacaga agggaatgat gaaaacaagg tggaggtgga
     1321 agaagaagct gacaacaaag acttcaaaga agatggagag aaaggggagc ctgtgagcac
     1381 tgtctagatc tgccctctgt gagatcataa tttggtaaca cgtaccttcc tgttgtaatg
     1441 ttaatagaga taaatatttt tatcagatat tttataaaca gtgcttttct ttagcatcat
     1501 tcaatctcag atcatcatca taccagttat tagttgcaaa atacctaaca tgacaccttt
     1561 atacattttg tgattatagt agtgcaaaat aggaaatgta tacttgcaac tttgtgaatt
     1621 tcattgtgtg taagttatgt attaaatctt tgagtttcaa ctttattctt atacgtggta
     1681 attttgcaga gtaagagaat tccaaaagaa agagtttggc acaactttgc tgtagttctc
     1741 taggttgctt ttataaagaa ggtcaactat tttcaggtaa tgccaagagt taggattgcc
     1801 attaccaaat ataactgtat tagtagcttg gaaagaatat aaaattttaa tttcattttt
     1861 gaagaaattt gaatgtttat ttcaggaggg cagttttgac tatatgtgta tgcacaaagt
     1921 tttgctggat ttatcataat aaaacagttc cacaaagata a
//
