LOCUS       NM_001077674            2141 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus H2.0-like homeobox (Hlx), mRNA.
ACCESSION   NM_001077674 XM_001064868 XM_344184
VERSION     NM_001077674.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2141)
  AUTHORS   Bates,M.D., Dunagan,D.T., Welch,L.C., Kaul,A. and Harvey,R.P.
  TITLE     The Hlx homeobox transcription factor is required early in enteric
            nervous system development
  JOURNAL   BMC Dev Biol 6, 33 (2006)
   PUBMED   16854219
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2141)
  AUTHORS   Mikhalkevich,N., Becknell,B., Caligiuri,M.A., Bates,M.D., Harvey,R.
            and Zheng,W.P.
  TITLE     Responsiveness of naive CD4 T cells to polarizing cytokine
            determines the ratio of Th1 and Th2 cell differentiation
  JOURNAL   J Immunol 176 (3), 1553-1560 (2006)
   PUBMED   16424184
REFERENCE   3  (bases 1 to 2141)
  AUTHORS   Quinn,L.M., Johnson,B.V., Nicholl,J., Sutherland,G.R. and
            Kalionis,B.
  TITLE     Isolation and identification of homeobox genes from the human
            placenta including a novel member of the Distal-less family, DLX4
  JOURNAL   Gene 187 (1), 55-61 (1997)
   PUBMED   9073066
REFERENCE   4  (bases 1 to 2141)
  AUTHORS   Hentsch,B., Lyons,I., Li,R., Hartley,L., Lints,T.J., Adams,J.M. and
            Harvey,R.P.
  TITLE     Hlx homeo box gene is essential for an inductive tissue interaction
            that drives expansion of embryonic liver and gut
  JOURNAL   Genes Dev 10 (1), 70-79 (1996)
   PUBMED   8557196
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC127513.1.
            
            On or before Nov 15, 2006 this sequence version replaced
            XM_344184.3, XM_001064868.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC127513.1, SRR8487226.3157.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494, SAMN16676789
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2141
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q26"
     gene            1..2141
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /note="H2.0-like homeobox"
                     /db_xref="GeneID:364069"
                     /db_xref="RGD:1311961"
     exon            1..905
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /inference="alignment:Splign:2.1.0"
     CDS             323..1753
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /note="homeobox protein HLX1; H2.0-like homeo box 1"
                     /codon_start=1
                     /product="H2.0-like homeobox protein"
                     /protein_id="NP_001071142.1"
                     /db_xref="GeneID:364069"
                     /db_xref="RGD:1311961"
                     /translation="MFAAGLAPFYASNFSLWSAAYCSSAGPGGCSFALDPAAVKKPSF
                     CIADILHAGVGEPGPAAEGLVGASAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSE
                     VPAGFPQRLSPLSAAYHQHLPQQPPTQQQQPQQQPPPPPRAGSLQPPTSGTRVVPHHS
                     GSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPTGVHLAGLQPSAG
                     QFFASLDPISEASAILSPLSSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWS
                     RAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEA
                     QAQKDKDKEAGEKPSGGVPAEGEREERSPSRSEGEAESESSDSESLDMAPSDTERTEG
                     TERSLHQTTVIKASAAGALITASSSASGSSFSFSSSSSLGSSNGSAGSASSLGSNCSE
                     LLPSHQPSVTSGPQSPEIAQVPLAGL"
     exon            906..1085
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /inference="alignment:Splign:2.1.0"
     exon            1086..1270
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..2116
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccctgtctcc ccggcttctg cggagtagca gaacgaggcc gcgtccgccg cctcgcccca
       61 gcgccgggcg atcgcctcca tccaccggac ggagagcttg cccgccgcgc cgcctttcaa
      121 gccaagccag gggcccaggc cgtggcgggc ggcgatcggg ccctcgccac gtccctcggt
      181 ggcgctaggg ctcccgggct ggccctccgc ttcggggcga gcggagaagc gaaagcagct
      241 cgggctgggc tgggacaccg cctctccccg agcacccacc cacttcccca ctcacccaag
      301 accccgccgg gatcctgcca ggatgttcgc agccggcctg gctcccttct acgcttccaa
      361 ctttagtctc tggtcagccg cctactgctc ctccgcgggc ccgggcggct gctccttcgc
      421 cttggacccg gccgctgtca agaaaccctc tttctgcatc gcggacatcc tgcacgccgg
      481 cgtcggggag ccgggacccg ctgcagaggg actggtgggg gcctcggcag ccctcaccgc
      541 acacttgggc tccgtgcacc cgcacgcttc cttccaagct gccgccagat ccccgctccg
      601 tcccaccccg gtggtggcgc cctcagaagt cccggctgga ttccctcagc ggctgtctcc
      661 gctctctgcc gcctaccacc agcatctccc gcagcaacca ccaacgcagc aacagcagcc
      721 gcagcaacag cccccgcctc caccccgggc gggctccctg cagccgccga cttcggggac
      781 gcgggtggtc ccccaccata gcggctccgc ccctgccccc tccagcaaag acctcaaatt
      841 tggtattgac cgaattttgt ctgcagaatt tgacccaaaa gtcaaggaag gcaacactct
      901 gagagatctc acatcgctgc taactggtgg gcggcccaca ggggtgcatc tggctggcct
      961 gcagccttcg gcgggacagt tcttcgcatc tctagatccc attagcgagg cgtctgccat
     1021 cctcagcccc ttaagctcca acccaagaaa ttctgttcaa catcaattcc aagacacgtt
     1081 tccaggtccc tatgctgtgc ttaccaagga caccatgcca cagacgtaca agcggaagcg
     1141 ctcctggtcc cgtgctgtct tttccaacct gcaaagaaaa ggcctggaga agaggtttga
     1201 gatccagaag tacgtgacca aaccagatcg aaagcagctg gcggccatgc tgggcctcac
     1261 ggatgcacag gtgaaggtgt ggttccagaa ccggaggatg aagtggcggc attctaagga
     1321 ggcgcaggcg caaaaggaca aggacaagga agcgggcgaa aagccttcgg gcggagtccc
     1381 cgccgaggga gaaagagaag agaggagccc cagccgttcc gagggcgaag ccgagagcga
     1441 gagcagtgac tcggagtccc tggacatggc ccccagcgac acagaacgga ctgagggaac
     1501 agagaggtcc ctgcaccaaa ctacagtcat caaggcctca gccgcgggtg ccctcatcac
     1561 agccagcagc agcgcgagtg ggagcagctt cagcttcagc agctccagca gcctgggtag
     1621 cagcaacggc agcgcgggga gcgccagcag ccttggcagc aactgctcgg agctgcttcc
     1681 ctcgcaccag ccctcagtca ccagcggtcc tcaaagccct gagattgccc aggttccgct
     1741 tgcaggttta tagactggac cgagggcatg gcgtgtagct tccccaacac tggctggaga
     1801 ttgtgcctac tttaagttgg tggcaagggt cgccgagatg ggagccggac gccgtgggca
     1861 gcctctttgg ggttcatgcc ttttctcttg ctgccaaggc tccctaaggc ccacaacccc
     1921 cttccccaca aagagtggag agttttaagg tccctggcca aagaaagaat tcgactgttc
     1981 tccctaccca agcagctcac actgtgaagt gttcggtgga actgttcctc tgagcaccag
     2041 gggtcttggc gtaaggacaa gctgcactta ggaggccttt aacttgtaaa taaaatgttt
     2101 actacggttt gtaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
