LOCUS       NM_001100764             894 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus HLF transcription factor, PAR bZIP family member
            (Hlf), mRNA.
ACCESSION   NM_001100764 XM_001073964 XM_003752366
VERSION     NM_001100764.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 894)
  AUTHORS   Hou,J.Y., Wang,Y.G., Ma,S.J., Yang,B.Y. and Li,Q.P.
  TITLE     Identification of a prognostic 5-Gene expression signature for
            gastric cancer
  JOURNAL   J Cancer Res Clin Oncol 143 (4), 619-629 (2017)
   PUBMED   28035468
REFERENCE   2  (bases 1 to 894)
  AUTHORS   Rajan,S., Chu Pham Dang,H., Djambazian,H., Zuzan,H., Fedyshyn,Y.,
            Ketela,T., Moffat,J., Hudson,T.J. and Sladek,R.
  TITLE     Analysis of early C2C12 myogenesis identifies stably and
            differentially expressed transcriptional regulators whose
            knock-down inhibits myoblast differentiation
  JOURNAL   Physiol Genomics 44 (2), 183-197 (2012)
   PUBMED   22147266
REFERENCE   3  (bases 1 to 894)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   4  (bases 1 to 894)
  AUTHORS   Falvey,E., Fleury-Olela,F. and Schibler,U.
  TITLE     The rat hepatic leukemia factor (HLF) gene encodes two
            transcriptional activators with distinct circadian rhythms, tissue
            distributions and target preferences
  JOURNAL   EMBO J 14 (17), 4307-4317 (1995)
   PUBMED   7556072
REFERENCE   5  (bases 1 to 894)
  AUTHORS   Hunger,S.P., Brown,R. and Cleary,M.L.
  TITLE     DNA-binding and transcriptional regulatory properties of hepatic
            leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia
            chimera E2A-HLF
  JOURNAL   Mol Cell Biol 14 (9), 5986-5996 (1994)
   PUBMED   8065331
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On or before Dec 17, 2019 this sequence version replaced
            XM_001073964.4, XM_003752366.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1399562.1,
                                           SRR22582416.1563155.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840116, SAMN16676785
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-115               JAXUCZ010000010.1  75708306-75708420   c
            116-451             JAXUCZ010000010.1  75705910-75706245   c
            452-672             JAXUCZ010000010.1  75660326-75660546   c
            673-894             JAXUCZ010000010.1  75655529-75655750   c
FEATURES             Location/Qualifiers
     source          1..894
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..894
                     /gene="Hlf"
                     /note="HLF transcription factor, PAR bZIP family member"
                     /db_xref="GeneID:690286"
                     /db_xref="RGD:1582828"
     CDS             1..888
                     /gene="Hlf"
                     /note="HLF, PAR bZIP transcription factor"
                     /codon_start=1
                     /product="hepatic leukemia factor"
                     /protein_id="NP_001094234.1"
                     /db_xref="GeneID:690286"
                     /db_xref="RGD:1582828"
                     /translation="MEKMSRQLPLNPTFIPPPYGVLRSLLENPLKLPLHPEDAFSKDR
                     DKGKKLDDGSNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPS
                     QHDHSPHPPGLQPASSTAPSVMDLSSRATAPLHPGIPSPNCMQNPIRPGQLLPANRNT
                     PSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVF
                     IPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRK
                     ELGKCKNILAKYEARHGPL"
     exon            1..115
                     /gene="Hlf"
                     /inference="alignment:Splign:2.1.0"
     exon            116..451
                     /gene="Hlf"
                     /inference="alignment:Splign:2.1.0"
     exon            452..672
                     /gene="Hlf"
                     /inference="alignment:Splign:2.1.0"
     exon            673..894
                     /gene="Hlf"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggagaaaa tgtcccgaca gctccccctg aaccctacct ttatcccgcc tccctacggc
       61 gtgctcaggt ccctgctgga gaacccgctg aagctccccc ttcatcctga agacgcattt
      121 agcaaagaca gagacaaagg taagaagctg gatgatggta gcaacagccc gaccgtcccc
      181 cagtcggcct tcttgggacc caccttatgg gacaaaaccc ttccctatga cggagatact
      241 ttccagttgg aatacatgga cctggaggag tttctgtcag aaaatggcat cccccctagt
      301 ccatcgcagc acgaccacag ccctcaccct cctggtttgc aacctgcttc ctccactgct
      361 ccttcagtca tggatctcag cagccgggcc acggcacccc tccaccctgg catcccgtct
      421 ccgaactgta tgcagaaccc catcagacca ggccagctgt tgccagcaaa ccgaaacaca
      481 ccgagtccca ttgaccccga caccatccag gtcccagtcg ggtatgaacc agaccccgca
      541 gaccttgccc tctccagcat cccggggcag gaaatgtttg accctcgcaa acggaagttc
      601 tccgaggaag aactgaagcc acagcccatg attaagaaag ctcgcaaagt cttcattcct
      661 gatgatttga aggatgacaa gtactgggcg aggcgcagaa agaacaatat ggcggccaag
      721 cgctcccgtg atgcccggcg gctgaaggag aaccagatcg caatccgggc ctcattcctg
      781 gagaaggaga actcggccct ccgccaggag gtggctgatt taaggaagga gctgggcaaa
      841 tgcaagaaca tacttgccaa gtacgaggcc aggcacgggc ccctgtagga tggc
//
