LOCUS       NM_001191813            2859 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus Holliday junction recognition protein (Hjurp),
            mRNA.
ACCESSION   NM_001191813 XM_237403
VERSION     NM_001191813.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2859)
  AUTHORS   Zasadzinska,E., Barnhart-Dailey,M.C., Kuich,P.H. and Foltz,D.R.
  TITLE     Dimerization of the CENP-A assembly factor HJURP is required for
            centromeric nucleosome deposition
  JOURNAL   EMBO J 32 (15), 2113-2124 (2013)
   PUBMED   23771058
REFERENCE   2  (bases 1 to 2859)
  AUTHORS   Burgess,R.J. and Zhang,Z.
  TITLE     Histone chaperones in nucleosome assembly and human disease
  JOURNAL   Nat Struct Mol Biol 20 (1), 14-22 (2013)
   PUBMED   23288364
  REMARK    Review article
REFERENCE   3  (bases 1 to 2859)
  AUTHORS   Kim,I.S., Lee,M., Park,K.C., Jeon,Y., Park,J.H., Hwang,E.J.,
            Jeon,T.I., Ko,S., Lee,H., Baek,S.H. and Kim,K.I.
  TITLE     Roles of Mis18alpha in epigenetic regulation of centromeric
            chromatin and CENP-A loading
  JOURNAL   Mol Cell 46 (3), 260-273 (2012)
   PUBMED   22516971
REFERENCE   4  (bases 1 to 2859)
  AUTHORS   Hu,H., Liu,Y., Wang,M., Fang,J., Huang,H., Yang,N., Li,Y., Wang,J.,
            Yao,X., Shi,Y., Li,G. and Xu,R.M.
  TITLE     Structure of a CENP-A-histone H4 heterodimer in complex with
            chaperone HJURP
  JOURNAL   Genes Dev 25 (9), 901-906 (2011)
   PUBMED   21478274
REFERENCE   5  (bases 1 to 2859)
  AUTHORS   Dunleavy,E.M., Roche,D., Tagami,H., Lacoste,N., Ray-Gallet,D.,
            Nakamura,Y., Daigo,Y., Nakatani,Y. and Almouzni-Pettinotti,G.
  TITLE     HJURP is a cell-cycle-dependent maintenance and deposition factor
            of CENP-A at centromeres
  JOURNAL   Cell 137 (3), 485-497 (2009)
   PUBMED   19410545
REFERENCE   6  (bases 1 to 2859)
  AUTHORS   Foltz,D.R., Jansen,L.E., Bailey,A.O., Yates,J.R. 3rd, Bassett,E.A.,
            Wood,S., Black,B.E. and Cleveland,D.W.
  TITLE     Centromere-specific assembly of CENP-a nucleosomes is mediated by
            HJURP
  JOURNAL   Cell 137 (3), 472-484 (2009)
   PUBMED   19410544
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            [WARNING] On Jul 25, 2024 this sequence was replaced by
            NM_001191813.2.
            
            On Jul 17, 2010 this sequence version replaced XM_237403.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN12840107 [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-96                JAXUCZ010000009.1  96315363-96315458   c
            97-163              JAXUCZ010000009.1  96315212-96315278   c
            164-219             JAXUCZ010000009.1  96312889-96312944   c
            220-256             JAXUCZ010000009.1  96310161-96310197   c
            257-354             JAXUCZ010000009.1  96308517-96308614   c
            355-447             JAXUCZ010000009.1  96307603-96307695   c
            448-526             JAXUCZ010000009.1  96306224-96306302   c
            527-2859            JAXUCZ010000009.1  96302530-96304862   c
FEATURES             Location/Qualifiers
     source          1..2859
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q35"
     gene            1..2859
                     /gene="Hjurp"
                     /gene_synonym="RGD1305846"
                     /note="Holliday junction recognition protein"
                     /db_xref="GeneID:316602"
                     /db_xref="RGD:1305846"
     CDS             1..2019
                     /gene="Hjurp"
                     /gene_synonym="RGD1305846"
                     /codon_start=1
                     /product="Holliday junction recognition protein"
                     /protein_id="NP_001178742.1"
                     /db_xref="GeneID:316602"
                     /db_xref="RGD:1305846"
                     /translation="MESMNLRDRPLDQRLKESSRRFQTYMQRLIAKYNQPFEDDPLVQ
                     MATLTYETPQGLRVWGGKLIKEEDEEHTQVIGGLSEQAPGGDSDSSGADTSLEEAEWP
                     SCNLTREASGDTGKHQLTVPGNTLKTDLRRKYLTQVDILLQDAEYFKNTQKGDGKDTV
                     TTCFPSWTSPVTPAPGCQDGIPAKSFGGPEGSASSCGDQASSYPCPADMTIVTRNDSF
                     SLLGASSNSVSNQCPEVDDISNVTISDLYEGMMHSMSRLLRSKPSCIISTKTSINRNW
                     KLKRRLSRKHGVHKNTTYCHRSKPFQRSSRKGPLHCSEPRKEARVLRDSKNLPHVDPH
                     KTDKTGLELESVPLEGSKLQVHKLSPAWKELQGLPQKYLGLSTVNHLGREDRVKALQW
                     LISPVKMAPRLRVPPGQVENWYREVKIKFEKLHQECCPSPEKRLRLTGPTQSWAADMY
                     RGGSKSPGSRQSVETHKLSSPLSREKTERPGEAFEDLRGRSVKTNSCLLRRGPSPEDS
                     PSQSPGHSQQRSGHLQEHNSEPIRKAAWPSTAISAPDFPDCGGHYDELKKEFNRLYQK
                     YCLVSPRHAKVTLCGRLSPVKAAAAVPGQTEHLKRLNPDSPLQSSQKWSPSPDWRIRI
                     PQDSTAVEGHRSAQTASAVVRGPWLSTKRRKLSYPAKSPDSSGAAGRL"
     exon            1..96
                     /gene="Hjurp"
                     /gene_synonym="RGD1305846"
                     /inference="alignment:Splign:2.1.0"
     exon            97..163
                     /gene="Hjurp"
                     /gene_synonym="RGD1305846"
                     /inference="alignment:Splign:2.1.0"
     exon            164..219
                     /gene="Hjurp"
                     /gene_synonym="RGD1305846"
                     /inference="alignment:Splign:2.1.0"
     exon            220..256
                     /gene="Hjurp"
                     /gene_synonym="RGD1305846"
                     /inference="alignment:Splign:2.1.0"
     exon            257..354
                     /gene="Hjurp"
                     /gene_synonym="RGD1305846"
                     /inference="alignment:Splign:2.1.0"
     exon            355..447
                     /gene="Hjurp"
                     /gene_synonym="RGD1305846"
                     /inference="alignment:Splign:2.1.0"
     exon            448..526
                     /gene="Hjurp"
                     /gene_synonym="RGD1305846"
                     /inference="alignment:Splign:2.1.0"
     exon            527..2859
                     /gene="Hjurp"
                     /gene_synonym="RGD1305846"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggagtcta tgaatctgcg ggatcgcccg ctggatcagc gtctcaagga aagcagtaga
       61 cgcttccaga cgtacatgca gcggctgata gcgaagtaca accaaccctt tgaggatgac
      121 ccgttggtgc agatggccac gctgacttac gagacgcccc agggattgag agtctgggga
      181 ggaaagctga taaaggaaga agacgaggaa cacactcagg tgattggtgg attaagtgag
      241 caagctccag gaggtgattc cgacagcagc ggtgcagata caagcttaga ggaggcagaa
      301 tggccgtctt gcaacttgac gagagaagct tctggggata ctgggaagca tcagctgaca
      361 gtgcccggaa acaccttgaa aactgattta agaaggaagt acttgaccca ggtggatata
      421 ctgcttcagg acgcagaata ttttaagaac acacagaagg gagatggaaa agacacggtc
      481 acgacttgct ttccttcctg gacgtcacct gtcacaccag cccctggatg ccaggatggt
      541 atccctgcaa agagctttgg tggtcctgaa gggtctgctt catcctgcgg agaccaggct
      601 tcctcatacc cttgcccagc tgacatgacc attgtgacta gaaatgacag cttctcctta
      661 ctaggggcca gcagcaacag tgtaagcaac cagtgccctg aggttgatga catcagcaat
      721 gtgacaatca gcgatctgta tgaaggcatg atgcactcca tgagcaggct gctgcgctca
      781 aagccgtcgt gcatcatctc caccaagacc tccattaaca ggaactggaa gctcaagagg
      841 aggctctcac gaaagcatgg ggtgcacaag aacacgacat actgccacag gagcaaaccc
      901 ttccagagga gctctaggaa ggggcccctg cactgctcag agcccaggaa agaggccaga
      961 gtattaaggg actccaagaa cttgccgcat gttgatcccc acaagacaga caagacaggc
     1021 ttagaactgg aaagtgttcc tcttgaagga agcaaactcc aagtccataa attgagtcca
     1081 gcttggaagg agctccaggg gctgcctcag aagtatttgg gcttaagcac agtaaaccac
     1141 cttgggcgag aagacagggt gaaggcatta cagtggttaa tttcacccgt taaaatggct
     1201 cccaggctga gggtgcctcc aggtcaggta gagaactggt atagagaggt taaaatcaaa
     1261 tttgagaaac tccatcagga atgttgccca tctcctgaga aacggcttcg cctgactggc
     1321 cctacgcagt cttgggctgc agacatgtac agaggtggct ctaaaagccc aggcagccgc
     1381 cagagtgtag aaacccacaa gctgagttca cctttgagca gagagaagac agagaggcca
     1441 ggtgaagctt ttgaagacct gaggggaagg tctgtcaaga caaatagctg tctcctaagg
     1501 aggggccctt ctccagagga cagcccgtca caaagtccag gtcattctca acagaggtct
     1561 ggccatcttc aagaacataa ttctgaacca atcagaaagg cagcatggcc cagtacagcc
     1621 atttcagcac cggactttcc agactgtgga ggtcactatg acgagcttaa aaaagaattc
     1681 aacagacttt atcagaagta ttgtctggtg tcacctcggc atgcgaaggt gactttgtgt
     1741 ggcagactat ctccagtgaa agctgctgca gctgttcccg gtcaaacaga gcacttgaaa
     1801 agattaaatc cagactctcc actccagagt tcccagaaat ggtcgccatc tcctgactgg
     1861 cgcataagaa ttccacagga ttcaactgca gttgagggtc acaggtctgc acagactgct
     1921 agtgctgttg tgagaggccc ttggttgtca acaaagaggc gcaagttgtc atacccggcc
     1981 aagtctccag attcctcggg agcagcaggc cggctctgag tgtcctgact gctggctgcg
     2041 tgtttgtccg ttggacatga tgtgtagtca gtagctgctt tgagggagaa gacttggcag
     2101 acgcttttct ctttggaggt gggcccagag catcaagtgt gctgaacaat ctttcactgc
     2161 agctcccagt agccacttgg cctctgccca gccacctccc ccgcaccata tcacagcgcc
     2221 acctctgttc tgccttgggc ttctccagcc agcctcgaat atgtctctaa atcatattca
     2281 ggggattctc gatggcagtt ttccttttga ctttaactgc ttacattgtc tttgctcccc
     2341 gctccccaca cccatcttca ccttcctctc ttctgctttt gtgtaggtaa gtgcccttct
     2401 ggaggacatg gtgtaagtcc atgggttggg taatagcccg gaccctgctc ccacccgttg
     2461 gcttagtctc aggagctctg gtttgggggt ggggtggggg agatgttttg tttttgaggc
     2521 agtcttacat agcttggtct gaccttgaac tcgttggatg gttgaggtga cttcaagttc
     2581 ctgatcctcc tgcctctgcc tccgtttccc aaattctgag gctaatcttt gttttcggat
     2641 ttatttccat gggtacaaca ctttatgagc tgattgaact gccaagaagg gaagggaccc
     2701 acctggggta gagccatcga tacaaggagc agggccagac ctcagacttc aacaatacta
     2761 gctgggtctc tggtcacctg gtgtggcagg tatccctggc agggtatgcc cgccagcagg
     2821 ctcccttcgc tcttggcctg agctgcttgt ctagctgtc
//
